Serosal invasion in TNM staging of mass-forming intrahepatic cholangiocarcinoma View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2005-12

AUTHORS

Takahiro Uenishi, Osamu Yamazaki, Takatsugu Yamamoto, Kazuhiro Hirohashi, Hiromu Tanaka, Shogo Tanaka, Seikan Hai, Shoji Kubo

ABSTRACT

BACKGROUND/PURPOSE: The Liver Cancer Study Group of Japan established a tumor-nodule-metastasis (TNM) staging system for mass-forming intrahepatic cholangiocarcinoma, with T determined by tumor number and size and vascular or serosal invasion. Serosal invasion is not considered in the designation established by the International Union Against Cancer. METHODS: Sixty-three patients who underwent hepatic resection for mass-forming intrahepatic cholangiocarcinoma were investigated retrospectively, with the investigation including univariate and multivariate analyses of potential prognostic factors. RESULTS: By log-rank test, tumor size more than 3.0 cm, vascular invasion, lymph node metastasis, intrahepatic metastasis, and involved resection margin, but not serosal invasion, were associated significantly with poor prognosis. Even in patients with serosal invasion, the postoperative outcome was much better in those without than in those with vascular invasion. Multivariate analysis identified vascular invasion, lymph node metastasis, and an involved resection margin as independent prognostic factors. When serosal invasion was excluded from tumor staging, the 5-year survival rates became more clearly stratified: 100% in those with stage I disease, 62% in those with stage II, 25% in those with stage III, and 7% for patients with stage IV. CONCLUSIONS: Serosal invasion showed no survival impact after hepatic resection for mass-forming intrahepatic cholangiocarcinoma. When serosal invasion was omitted from the TNM staging proposed by the Liver Cancer Study Group of Japan, stratification of postoperative survival between stages was more effective. More... »

PAGES

479-483

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00534-005-1026-8

DOI

http://dx.doi.org/10.1007/s00534-005-1026-8

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1018861064

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/16365823


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1112", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Oncology and Carcinogenesis", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adult", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged, 80 and over", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Bile Duct Neoplasms", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Bile Ducts, Intrahepatic", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cholangiocarcinoma", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Lymphatic Metastasis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Middle Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Multivariate Analysis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Neoplasm Staging", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Prognosis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Retrospective Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Survival Analysis", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Osaka City University", 
          "id": "https://www.grid.ac/institutes/grid.261445.0", 
          "name": [
            "Department of Hepato-Biliary-Pancreatic Surgery, Osaka City University Graduate School of Medicine, 1-4-3 Asahimachi, Abeno-ku, 545-8585, Osaka, Japan", 
            "Department of Surgery, Ishikiri Seiki Hospital, Osaka, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Uenishi", 
        "givenName": "Takahiro", 
        "id": "sg:person.0724313236.18", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0724313236.18"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Osaka City General Hospital", 
          "id": "https://www.grid.ac/institutes/grid.416948.6", 
          "name": [
            "Department of Gastrointestinal Surgery, Osaka City General Hospital, Osaka, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Yamazaki", 
        "givenName": "Osamu", 
        "id": "sg:person.01237566315.05", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01237566315.05"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Surgery, Ishikiri Seiki Hospital, Osaka, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Yamamoto", 
        "givenName": "Takatsugu", 
        "id": "sg:person.013612630514.29", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013612630514.29"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Osaka City University", 
          "id": "https://www.grid.ac/institutes/grid.261445.0", 
          "name": [
            "Department of Hepato-Biliary-Pancreatic Surgery, Osaka City University Graduate School of Medicine, 1-4-3 Asahimachi, Abeno-ku, 545-8585, Osaka, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hirohashi", 
        "givenName": "Kazuhiro", 
        "id": "sg:person.01131736114.10", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01131736114.10"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Osaka City University", 
          "id": "https://www.grid.ac/institutes/grid.261445.0", 
          "name": [
            "Department of Hepato-Biliary-Pancreatic Surgery, Osaka City University Graduate School of Medicine, 1-4-3 Asahimachi, Abeno-ku, 545-8585, Osaka, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Tanaka", 
        "givenName": "Hiromu", 
        "id": "sg:person.01021350614.43", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01021350614.43"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Osaka City University", 
          "id": "https://www.grid.ac/institutes/grid.261445.0", 
          "name": [
            "Department of Hepato-Biliary-Pancreatic Surgery, Osaka City University Graduate School of Medicine, 1-4-3 Asahimachi, Abeno-ku, 545-8585, Osaka, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Tanaka", 
        "givenName": "Shogo", 
        "id": "sg:person.07717522224.30", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07717522224.30"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Osaka City University", 
          "id": "https://www.grid.ac/institutes/grid.261445.0", 
          "name": [
            "Department of Hepato-Biliary-Pancreatic Surgery, Osaka City University Graduate School of Medicine, 1-4-3 Asahimachi, Abeno-ku, 545-8585, Osaka, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hai", 
        "givenName": "Seikan", 
        "id": "sg:person.0667653540.55", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0667653540.55"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Osaka City University", 
          "id": "https://www.grid.ac/institutes/grid.261445.0", 
          "name": [
            "Department of Hepato-Biliary-Pancreatic Surgery, Osaka City University Graduate School of Medicine, 1-4-3 Asahimachi, Abeno-ku, 545-8585, Osaka, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kubo", 
        "givenName": "Shoji", 
        "id": "sg:person.0761414122.21", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0761414122.21"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1016/s0002-9610(01)00628-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002674965"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/hep.510270201", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004378271"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00268-001-0291-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004801848", 
          "https://doi.org/10.1007/s00268-001-0291-1"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00268-001-0291-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004801848", 
          "https://doi.org/10.1007/s00268-001-0291-1"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0002-9610(02)00853-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010968994"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1159/000439101", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013268622"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00534-002-0724-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013700745", 
          "https://doi.org/10.1007/s00534-002-0724-8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s005340050092", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014759806", 
          "https://doi.org/10.1007/s005340050092"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/bjs.1800831108", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017704377"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1046/j.0007-1323.2001.01879.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021376410"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1067/msy.2000.104673", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021547795"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/(sici)1097-0142(19981101)83:9<1923::aid-cncr7>3.0.co;2-#", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024123175"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/archsurg.1995.01430100051011", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026507049"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00534-002-0732-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026602769", 
          "https://doi.org/10.1007/s00534-002-0732-8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/hep.1840180109", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027281080"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/(sici)1096-9098(199811)69:3<162::aid-jso8>3.0.co;2-l", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027559248"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1046/j.0007-1323.2001.01784.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028872040"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/1097-0142(20011101)92:9<2374::aid-cncr1585>3.0.co;2-l", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039653095"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/archsurg.1995.01430030040006", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044113937"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/1097-0142(19911201)68:11<2411::aid-cncr2820681114>3.0.co;2-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045036745"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/1097-0142(19870915)60:6<1400::aid-cncr2820600639>3.0.co;2-w", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049716811"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1046/j.1365-2168.2002.02268.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051571188"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1159/000018770", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051601482"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00534-002-0842-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052520170", 
          "https://doi.org/10.1007/s00534-002-0842-3"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s1072-7515(97)00088-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1054680256"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00000658-199801000-00011", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060134679"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00000658-199801000-00011", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060134679"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00000658-199801000-00011", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060134679"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00000658-199801000-00011", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060134679"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1075047533", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1078393934", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2005-12", 
    "datePublishedReg": "2005-12-01", 
    "description": "BACKGROUND/PURPOSE: The Liver Cancer Study Group of Japan established a tumor-nodule-metastasis (TNM) staging system for mass-forming intrahepatic cholangiocarcinoma, with T determined by tumor number and size and vascular or serosal invasion. Serosal invasion is not considered in the designation established by the International Union Against Cancer.\nMETHODS: Sixty-three patients who underwent hepatic resection for mass-forming intrahepatic cholangiocarcinoma were investigated retrospectively, with the investigation including univariate and multivariate analyses of potential prognostic factors.\nRESULTS: By log-rank test, tumor size more than 3.0 cm, vascular invasion, lymph node metastasis, intrahepatic metastasis, and involved resection margin, but not serosal invasion, were associated significantly with poor prognosis. Even in patients with serosal invasion, the postoperative outcome was much better in those without than in those with vascular invasion. Multivariate analysis identified vascular invasion, lymph node metastasis, and an involved resection margin as independent prognostic factors. When serosal invasion was excluded from tumor staging, the 5-year survival rates became more clearly stratified: 100% in those with stage I disease, 62% in those with stage II, 25% in those with stage III, and 7% for patients with stage IV.\nCONCLUSIONS: Serosal invasion showed no survival impact after hepatic resection for mass-forming intrahepatic cholangiocarcinoma. When serosal invasion was omitted from the TNM staging proposed by the Liver Cancer Study Group of Japan, stratification of postoperative survival between stages was more effective.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s00534-005-1026-8", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1043285", 
        "issn": [
          "1868-6974", 
          "1868-6982"
        ], 
        "name": "Journal of Hepato-Biliary-Pancreatic Sciences", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "6", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "12"
      }
    ], 
    "name": "Serosal invasion in TNM staging of mass-forming intrahepatic cholangiocarcinoma", 
    "pagination": "479-483", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "59dde8ce9bf8a4125fe1105ac65009f4ffe1affd56dbce61b919a5887d3bff16"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "16365823"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "9431940"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s00534-005-1026-8"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1018861064"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s00534-005-1026-8", 
      "https://app.dimensions.ai/details/publication/pub.1018861064"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T12:39", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000363_0000000363/records_70046_00000000.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1007%2Fs00534-005-1026-8"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00534-005-1026-8'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00534-005-1026-8'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00534-005-1026-8'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00534-005-1026-8'


 

This table displays all metadata directly associated to this object as RDF triples.

272 TRIPLES      21 PREDICATES      72 URIs      37 LITERALS      25 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s00534-005-1026-8 schema:about N02e9026c5f944c49b80c740c3c047446
2 N257b4e7834404099a9e61af5f34c4c18
3 N3239d6aa3be940d7a4737cb7cc87aba0
4 N350b91f631fb4dd4aebf29b3cead79d1
5 N3b2b43b35df24b259878ee57db1b48cd
6 N3e342ce57c2d40eda33cdedfd255a167
7 N486a9b7440aa4881a23b9bfadca4ac86
8 N501f0d5717d140a7a01e6538aab216e2
9 N5361130a7c8c4cdc8a4a624a9baaf501
10 N6765514a0da743649a77b798292e6820
11 N6a3ba11c5ed14467a2ed823bfb6c6088
12 N7e3f0b5f10374e6b843a0bf272165ab2
13 Nc35f2ad9ba6d4c0e8d4e9d54acd18fd6
14 Ndf5c99a3072944afbc8cb96e0240f7c6
15 Ne9399be2180c456c8126d56cb573dfac
16 Nef49e31604d6433c80a4d7de44d52088
17 anzsrc-for:11
18 anzsrc-for:1112
19 schema:author Nd0f636ac21c544daaaf367d4d05df349
20 schema:citation sg:pub.10.1007/s00268-001-0291-1
21 sg:pub.10.1007/s00534-002-0724-8
22 sg:pub.10.1007/s00534-002-0732-8
23 sg:pub.10.1007/s00534-002-0842-3
24 sg:pub.10.1007/s005340050092
25 https://app.dimensions.ai/details/publication/pub.1075047533
26 https://app.dimensions.ai/details/publication/pub.1078393934
27 https://doi.org/10.1001/archsurg.1995.01430030040006
28 https://doi.org/10.1001/archsurg.1995.01430100051011
29 https://doi.org/10.1002/(sici)1096-9098(199811)69:3<162::aid-jso8>3.0.co;2-l
30 https://doi.org/10.1002/(sici)1097-0142(19981101)83:9<1923::aid-cncr7>3.0.co;2-#
31 https://doi.org/10.1002/1097-0142(19870915)60:6<1400::aid-cncr2820600639>3.0.co;2-w
32 https://doi.org/10.1002/1097-0142(19911201)68:11<2411::aid-cncr2820681114>3.0.co;2-0
33 https://doi.org/10.1002/1097-0142(20011101)92:9<2374::aid-cncr1585>3.0.co;2-l
34 https://doi.org/10.1002/bjs.1800831108
35 https://doi.org/10.1002/hep.1840180109
36 https://doi.org/10.1002/hep.510270201
37 https://doi.org/10.1016/s0002-9610(01)00628-6
38 https://doi.org/10.1016/s0002-9610(02)00853-x
39 https://doi.org/10.1016/s1072-7515(97)00088-4
40 https://doi.org/10.1046/j.0007-1323.2001.01784.x
41 https://doi.org/10.1046/j.0007-1323.2001.01879.x
42 https://doi.org/10.1046/j.1365-2168.2002.02268.x
43 https://doi.org/10.1067/msy.2000.104673
44 https://doi.org/10.1097/00000658-199801000-00011
45 https://doi.org/10.1159/000018770
46 https://doi.org/10.1159/000439101
47 schema:datePublished 2005-12
48 schema:datePublishedReg 2005-12-01
49 schema:description BACKGROUND/PURPOSE: The Liver Cancer Study Group of Japan established a tumor-nodule-metastasis (TNM) staging system for mass-forming intrahepatic cholangiocarcinoma, with T determined by tumor number and size and vascular or serosal invasion. Serosal invasion is not considered in the designation established by the International Union Against Cancer. METHODS: Sixty-three patients who underwent hepatic resection for mass-forming intrahepatic cholangiocarcinoma were investigated retrospectively, with the investigation including univariate and multivariate analyses of potential prognostic factors. RESULTS: By log-rank test, tumor size more than 3.0 cm, vascular invasion, lymph node metastasis, intrahepatic metastasis, and involved resection margin, but not serosal invasion, were associated significantly with poor prognosis. Even in patients with serosal invasion, the postoperative outcome was much better in those without than in those with vascular invasion. Multivariate analysis identified vascular invasion, lymph node metastasis, and an involved resection margin as independent prognostic factors. When serosal invasion was excluded from tumor staging, the 5-year survival rates became more clearly stratified: 100% in those with stage I disease, 62% in those with stage II, 25% in those with stage III, and 7% for patients with stage IV. CONCLUSIONS: Serosal invasion showed no survival impact after hepatic resection for mass-forming intrahepatic cholangiocarcinoma. When serosal invasion was omitted from the TNM staging proposed by the Liver Cancer Study Group of Japan, stratification of postoperative survival between stages was more effective.
50 schema:genre research_article
51 schema:inLanguage en
52 schema:isAccessibleForFree false
53 schema:isPartOf N89785d07fc6747d1bca76f206b8343e6
54 Ncf5ccd8193904d06927f082429b98912
55 sg:journal.1043285
56 schema:name Serosal invasion in TNM staging of mass-forming intrahepatic cholangiocarcinoma
57 schema:pagination 479-483
58 schema:productId N186e95a6968e40ae92de16a73480ae65
59 N78629851c5af45b38deb92d854155342
60 N8d2485266b4e454bbaa03a8dc5fcdac4
61 N99203c4173d248d4a59ad2b4e184794f
62 Ne543e0edb5ac48d49e157f46f1a37fac
63 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018861064
64 https://doi.org/10.1007/s00534-005-1026-8
65 schema:sdDatePublished 2019-04-11T12:39
66 schema:sdLicense https://scigraph.springernature.com/explorer/license/
67 schema:sdPublisher Nf0a5e342ba964559a4e4290a81326522
68 schema:url http://link.springer.com/10.1007%2Fs00534-005-1026-8
69 sgo:license sg:explorer/license/
70 sgo:sdDataset articles
71 rdf:type schema:ScholarlyArticle
72 N02e9026c5f944c49b80c740c3c047446 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
73 schema:name Aged
74 rdf:type schema:DefinedTerm
75 N186e95a6968e40ae92de16a73480ae65 schema:name doi
76 schema:value 10.1007/s00534-005-1026-8
77 rdf:type schema:PropertyValue
78 N1dc7c0f0c340489a92a0aa17d1080ce7 rdf:first sg:person.0761414122.21
79 rdf:rest rdf:nil
80 N257b4e7834404099a9e61af5f34c4c18 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
81 schema:name Male
82 rdf:type schema:DefinedTerm
83 N3239d6aa3be940d7a4737cb7cc87aba0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
84 schema:name Female
85 rdf:type schema:DefinedTerm
86 N350b91f631fb4dd4aebf29b3cead79d1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
87 schema:name Cholangiocarcinoma
88 rdf:type schema:DefinedTerm
89 N3b2b43b35df24b259878ee57db1b48cd schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
90 schema:name Neoplasm Staging
91 rdf:type schema:DefinedTerm
92 N3e342ce57c2d40eda33cdedfd255a167 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
93 schema:name Bile Ducts, Intrahepatic
94 rdf:type schema:DefinedTerm
95 N486a9b7440aa4881a23b9bfadca4ac86 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
96 schema:name Lymphatic Metastasis
97 rdf:type schema:DefinedTerm
98 N501f0d5717d140a7a01e6538aab216e2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
99 schema:name Aged, 80 and over
100 rdf:type schema:DefinedTerm
101 N5361130a7c8c4cdc8a4a624a9baaf501 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
102 schema:name Retrospective Studies
103 rdf:type schema:DefinedTerm
104 N616ead62e2ec44e382c093f28dfc2119 rdf:first sg:person.01131736114.10
105 rdf:rest Ne805a4a2e5b7491190f805d2dc7c0949
106 N6765514a0da743649a77b798292e6820 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
107 schema:name Multivariate Analysis
108 rdf:type schema:DefinedTerm
109 N6a3ba11c5ed14467a2ed823bfb6c6088 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
110 schema:name Bile Duct Neoplasms
111 rdf:type schema:DefinedTerm
112 N78629851c5af45b38deb92d854155342 schema:name nlm_unique_id
113 schema:value 9431940
114 rdf:type schema:PropertyValue
115 N7e3f0b5f10374e6b843a0bf272165ab2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
116 schema:name Humans
117 rdf:type schema:DefinedTerm
118 N89785d07fc6747d1bca76f206b8343e6 schema:issueNumber 6
119 rdf:type schema:PublicationIssue
120 N8979a63a4e7e44129f0e4a0d585318c4 rdf:first sg:person.01237566315.05
121 rdf:rest N993e956143dd4e5b806909ca3c18af10
122 N8d2485266b4e454bbaa03a8dc5fcdac4 schema:name pubmed_id
123 schema:value 16365823
124 rdf:type schema:PropertyValue
125 N99203c4173d248d4a59ad2b4e184794f schema:name readcube_id
126 schema:value 59dde8ce9bf8a4125fe1105ac65009f4ffe1affd56dbce61b919a5887d3bff16
127 rdf:type schema:PropertyValue
128 N993e956143dd4e5b806909ca3c18af10 rdf:first sg:person.013612630514.29
129 rdf:rest N616ead62e2ec44e382c093f28dfc2119
130 Nb7a2a6f528304e268aee2cf509056acd rdf:first sg:person.07717522224.30
131 rdf:rest Ndcd7e66ef82b46d5b94a78d3d15bc88e
132 Nc35f2ad9ba6d4c0e8d4e9d54acd18fd6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
133 schema:name Survival Analysis
134 rdf:type schema:DefinedTerm
135 Ncf5ccd8193904d06927f082429b98912 schema:volumeNumber 12
136 rdf:type schema:PublicationVolume
137 Nd0f636ac21c544daaaf367d4d05df349 rdf:first sg:person.0724313236.18
138 rdf:rest N8979a63a4e7e44129f0e4a0d585318c4
139 Nd73d604463ef46bb9590747c0df40cc4 schema:name Department of Surgery, Ishikiri Seiki Hospital, Osaka, Japan
140 rdf:type schema:Organization
141 Ndcd7e66ef82b46d5b94a78d3d15bc88e rdf:first sg:person.0667653540.55
142 rdf:rest N1dc7c0f0c340489a92a0aa17d1080ce7
143 Ndf5c99a3072944afbc8cb96e0240f7c6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
144 schema:name Middle Aged
145 rdf:type schema:DefinedTerm
146 Ne543e0edb5ac48d49e157f46f1a37fac schema:name dimensions_id
147 schema:value pub.1018861064
148 rdf:type schema:PropertyValue
149 Ne805a4a2e5b7491190f805d2dc7c0949 rdf:first sg:person.01021350614.43
150 rdf:rest Nb7a2a6f528304e268aee2cf509056acd
151 Ne9399be2180c456c8126d56cb573dfac schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
152 schema:name Adult
153 rdf:type schema:DefinedTerm
154 Nef49e31604d6433c80a4d7de44d52088 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
155 schema:name Prognosis
156 rdf:type schema:DefinedTerm
157 Nf0a5e342ba964559a4e4290a81326522 schema:name Springer Nature - SN SciGraph project
158 rdf:type schema:Organization
159 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
160 schema:name Medical and Health Sciences
161 rdf:type schema:DefinedTerm
162 anzsrc-for:1112 schema:inDefinedTermSet anzsrc-for:
163 schema:name Oncology and Carcinogenesis
164 rdf:type schema:DefinedTerm
165 sg:journal.1043285 schema:issn 1868-6974
166 1868-6982
167 schema:name Journal of Hepato-Biliary-Pancreatic Sciences
168 rdf:type schema:Periodical
169 sg:person.01021350614.43 schema:affiliation https://www.grid.ac/institutes/grid.261445.0
170 schema:familyName Tanaka
171 schema:givenName Hiromu
172 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01021350614.43
173 rdf:type schema:Person
174 sg:person.01131736114.10 schema:affiliation https://www.grid.ac/institutes/grid.261445.0
175 schema:familyName Hirohashi
176 schema:givenName Kazuhiro
177 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01131736114.10
178 rdf:type schema:Person
179 sg:person.01237566315.05 schema:affiliation https://www.grid.ac/institutes/grid.416948.6
180 schema:familyName Yamazaki
181 schema:givenName Osamu
182 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01237566315.05
183 rdf:type schema:Person
184 sg:person.013612630514.29 schema:affiliation Nd73d604463ef46bb9590747c0df40cc4
185 schema:familyName Yamamoto
186 schema:givenName Takatsugu
187 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013612630514.29
188 rdf:type schema:Person
189 sg:person.0667653540.55 schema:affiliation https://www.grid.ac/institutes/grid.261445.0
190 schema:familyName Hai
191 schema:givenName Seikan
192 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0667653540.55
193 rdf:type schema:Person
194 sg:person.0724313236.18 schema:affiliation https://www.grid.ac/institutes/grid.261445.0
195 schema:familyName Uenishi
196 schema:givenName Takahiro
197 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0724313236.18
198 rdf:type schema:Person
199 sg:person.0761414122.21 schema:affiliation https://www.grid.ac/institutes/grid.261445.0
200 schema:familyName Kubo
201 schema:givenName Shoji
202 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0761414122.21
203 rdf:type schema:Person
204 sg:person.07717522224.30 schema:affiliation https://www.grid.ac/institutes/grid.261445.0
205 schema:familyName Tanaka
206 schema:givenName Shogo
207 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07717522224.30
208 rdf:type schema:Person
209 sg:pub.10.1007/s00268-001-0291-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004801848
210 https://doi.org/10.1007/s00268-001-0291-1
211 rdf:type schema:CreativeWork
212 sg:pub.10.1007/s00534-002-0724-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013700745
213 https://doi.org/10.1007/s00534-002-0724-8
214 rdf:type schema:CreativeWork
215 sg:pub.10.1007/s00534-002-0732-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026602769
216 https://doi.org/10.1007/s00534-002-0732-8
217 rdf:type schema:CreativeWork
218 sg:pub.10.1007/s00534-002-0842-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052520170
219 https://doi.org/10.1007/s00534-002-0842-3
220 rdf:type schema:CreativeWork
221 sg:pub.10.1007/s005340050092 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014759806
222 https://doi.org/10.1007/s005340050092
223 rdf:type schema:CreativeWork
224 https://app.dimensions.ai/details/publication/pub.1075047533 schema:CreativeWork
225 https://app.dimensions.ai/details/publication/pub.1078393934 schema:CreativeWork
226 https://doi.org/10.1001/archsurg.1995.01430030040006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044113937
227 rdf:type schema:CreativeWork
228 https://doi.org/10.1001/archsurg.1995.01430100051011 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026507049
229 rdf:type schema:CreativeWork
230 https://doi.org/10.1002/(sici)1096-9098(199811)69:3<162::aid-jso8>3.0.co;2-l schema:sameAs https://app.dimensions.ai/details/publication/pub.1027559248
231 rdf:type schema:CreativeWork
232 https://doi.org/10.1002/(sici)1097-0142(19981101)83:9<1923::aid-cncr7>3.0.co;2-# schema:sameAs https://app.dimensions.ai/details/publication/pub.1024123175
233 rdf:type schema:CreativeWork
234 https://doi.org/10.1002/1097-0142(19870915)60:6<1400::aid-cncr2820600639>3.0.co;2-w schema:sameAs https://app.dimensions.ai/details/publication/pub.1049716811
235 rdf:type schema:CreativeWork
236 https://doi.org/10.1002/1097-0142(19911201)68:11<2411::aid-cncr2820681114>3.0.co;2-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045036745
237 rdf:type schema:CreativeWork
238 https://doi.org/10.1002/1097-0142(20011101)92:9<2374::aid-cncr1585>3.0.co;2-l schema:sameAs https://app.dimensions.ai/details/publication/pub.1039653095
239 rdf:type schema:CreativeWork
240 https://doi.org/10.1002/bjs.1800831108 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017704377
241 rdf:type schema:CreativeWork
242 https://doi.org/10.1002/hep.1840180109 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027281080
243 rdf:type schema:CreativeWork
244 https://doi.org/10.1002/hep.510270201 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004378271
245 rdf:type schema:CreativeWork
246 https://doi.org/10.1016/s0002-9610(01)00628-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002674965
247 rdf:type schema:CreativeWork
248 https://doi.org/10.1016/s0002-9610(02)00853-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1010968994
249 rdf:type schema:CreativeWork
250 https://doi.org/10.1016/s1072-7515(97)00088-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1054680256
251 rdf:type schema:CreativeWork
252 https://doi.org/10.1046/j.0007-1323.2001.01784.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1028872040
253 rdf:type schema:CreativeWork
254 https://doi.org/10.1046/j.0007-1323.2001.01879.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1021376410
255 rdf:type schema:CreativeWork
256 https://doi.org/10.1046/j.1365-2168.2002.02268.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1051571188
257 rdf:type schema:CreativeWork
258 https://doi.org/10.1067/msy.2000.104673 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021547795
259 rdf:type schema:CreativeWork
260 https://doi.org/10.1097/00000658-199801000-00011 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060134679
261 rdf:type schema:CreativeWork
262 https://doi.org/10.1159/000018770 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051601482
263 rdf:type schema:CreativeWork
264 https://doi.org/10.1159/000439101 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013268622
265 rdf:type schema:CreativeWork
266 https://www.grid.ac/institutes/grid.261445.0 schema:alternateName Osaka City University
267 schema:name Department of Hepato-Biliary-Pancreatic Surgery, Osaka City University Graduate School of Medicine, 1-4-3 Asahimachi, Abeno-ku, 545-8585, Osaka, Japan
268 Department of Surgery, Ishikiri Seiki Hospital, Osaka, Japan
269 rdf:type schema:Organization
270 https://www.grid.ac/institutes/grid.416948.6 schema:alternateName Osaka City General Hospital
271 schema:name Department of Gastrointestinal Surgery, Osaka City General Hospital, Osaka, Japan
272 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...