Analysis of factors associated with patient-reported physical functioning scores at discharge of allogeneic hematopoietic stem cell transplantation patients: a cross-sectional ... View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2021-06-12

AUTHORS

Masanobu Murao, Ryota Hamada, Tadakazu Kondo, Junsuke Miyasaka, Michiko Yoshida, Honami Yonezawa, Yasuyuki Arai, Junya Kanda, Manabu Nankaku, Ryosuke Ikeguchi, Akifumi Takaori-Kondo, Shuichi Matsuda

ABSTRACT

PurposeThe purpose of this study was to clarify the independent factors related to patient-reported physical functioning (PF) scores at discharge of patients who underwent allogeneic hematopoietic stem cell transplantation (allo-HSCT).MethodsA total of 103 patients who underwent allo-HSCT were included in this cross-sectional study. As a screening method, a single regression analysis was conducted with the PF domain in the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 at discharge as the dependent variable, and body mass index, adverse events related to HSCT, and objective physical functions as independent variables. Multiple regression analysis was performed with PF as the dependent variable and variables that passed the screening by single regression analysis and confounders as independent variables.ResultsThe mean PF score at discharge of the patients was 76.5 (standard deviation: 15.2). Based on the results of screening by the single regression analysis, length of stay, infections (+ / −), acute graft-versus-host disease grade, brief fatigue inventory score (BFI), knee extensor strength, and 6-min walk distance (6MWD) were included in the multiple regression analysis. BFI (B = − 11.94, p < 0.001) and 6MWD (per 10 m) (B = 0.56, p = 0.001) were extracted as significant independent variables governing the PF at discharge in the multiple regression model (adjusted R2 = 0.59).ConclusionHigher exercise tolerance and lower fatigue in patients who underwent allo-HSCT were associated independently with patient-reported better PF scores at discharge. More... »

PAGES

7569-7576

References to SciGraph publications

  • 2019-01-14. Graft Versus Host Disease Clinical Trials: Is it Time for Patients Centered Outcomes to Be the Primary Objective? in CURRENT HEMATOLOGIC MALIGNANCY REPORTS
  • 2015-09-14. Physical function and quality of life in patients with chronic GvHD: a summary of preclinical and clinical studies and a call for exercise intervention trials in patients in BONE MARROW TRANSPLANTATION
  • 2019-11-12. Effect of the severity of acute graft-versus-host disease on physical function after allogeneic hematopoietic stem cell transplantation in SUPPORTIVE CARE IN CANCER
  • 2018-01-25. Impaired skeletal muscle oxygenation following allogeneic hematopoietic stem cell transplantation is associated with exercise capacity in SUPPORTIVE CARE IN CANCER
  • 2012-04-12. Prevalence of sarcopenia and relevance of body composition, physiological function, fatigue, and health-related quality of life in patients before allogeneic hematopoietic stem cell transplantation in SUPPORTIVE CARE IN CANCER
  • 2011-05-23. Quality of life in patients before and after haematopoietic stem cell transplantation measured with the European Organization for Research and Treatment of Cancer (EORTC) Quality of Life Core Questionnaire QLQ-C30 in BONE MARROW TRANSPLANTATION
  • 2016-03-21. Recovery of physical function and quality of life in patients undergoing hematopoietic stem cell transplantation: a 1-year follow-up in BONE MARROW TRANSPLANTATION
  • 2011-04-09. Impaired physiological function and health-related QOL in patients before hematopoietic stem-cell transplantation in SUPPORTIVE CARE IN CANCER
  • 2018-02-08. Quality of life trajectories during the first year following hematopoietic cell transplantation: an inception cohort study in SUPPORTIVE CARE IN CANCER
  • 2018-08-30. Fatigue, Muscle Oxygen Consumption and Blood Flow to the Skeletal Muscle After Allogeneic Hematopoietic Stem Cell Transplantation in OXYGEN TRANSPORT TO TISSUE XL
  • 1992-08. Erratum to The MOS 36-item short form health survey (SF-36): I. Conceptual framework in PHARMACOECONOMICS
  • 2011-04-29. Long-term complications and side effects after allogeneic hematopoietic stem cell transplantation: an update in BLOOD CANCER JOURNAL
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s00520-021-06323-5

    DOI

    http://dx.doi.org/10.1007/s00520-021-06323-5

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1138792434

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/34120260


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Medical and Health Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1117", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Public Health and Health Services", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Cross-Sectional Studies", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Graft vs Host Disease", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Hematopoietic Stem Cell Transplantation", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Humans", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Patient Discharge", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Patient Reported Outcome Measures", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Quality of Life", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "affiliation": {
              "alternateName": "Rehabilitation Unit, Kyoto University Hospital, 54 Shogoin-Kawahara-cho, Sakyo-ku, 606-8507, Kyoto, Japan", 
              "id": "http://www.grid.ac/institutes/grid.411217.0", 
              "name": [
                "Rehabilitation Unit, Kyoto University Hospital, 54 Shogoin-Kawahara-cho, Sakyo-ku, 606-8507, Kyoto, Japan"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Murao", 
            "givenName": "Masanobu", 
            "id": "sg:person.016151633437.69", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016151633437.69"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Rehabilitation Unit, Kyoto University Hospital, 54 Shogoin-Kawahara-cho, Sakyo-ku, 606-8507, Kyoto, Japan", 
              "id": "http://www.grid.ac/institutes/grid.411217.0", 
              "name": [
                "Rehabilitation Unit, Kyoto University Hospital, 54 Shogoin-Kawahara-cho, Sakyo-ku, 606-8507, Kyoto, Japan"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Hamada", 
            "givenName": "Ryota", 
            "id": "sg:person.012131144057.36", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012131144057.36"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Hematology and Oncology, Graduate School of Medicine, Kyoto University, Sakyo-ku, Kyoto, Japan", 
              "id": "http://www.grid.ac/institutes/grid.258799.8", 
              "name": [
                "Department of Hematology and Oncology, Graduate School of Medicine, Kyoto University, Sakyo-ku, Kyoto, Japan"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Kondo", 
            "givenName": "Tadakazu", 
            "id": "sg:person.0666225507.36", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0666225507.36"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Rehabilitation Unit, Kyoto University Hospital, 54 Shogoin-Kawahara-cho, Sakyo-ku, 606-8507, Kyoto, Japan", 
              "id": "http://www.grid.ac/institutes/grid.411217.0", 
              "name": [
                "Rehabilitation Unit, Kyoto University Hospital, 54 Shogoin-Kawahara-cho, Sakyo-ku, 606-8507, Kyoto, Japan"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Miyasaka", 
            "givenName": "Junsuke", 
            "id": "sg:person.014555237463.36", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014555237463.36"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Rehabilitation Unit, Kyoto University Hospital, 54 Shogoin-Kawahara-cho, Sakyo-ku, 606-8507, Kyoto, Japan", 
              "id": "http://www.grid.ac/institutes/grid.411217.0", 
              "name": [
                "Rehabilitation Unit, Kyoto University Hospital, 54 Shogoin-Kawahara-cho, Sakyo-ku, 606-8507, Kyoto, Japan"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Yoshida", 
            "givenName": "Michiko", 
            "id": "sg:person.015117046057.73", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015117046057.73"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Rehabilitation Unit, Kyoto University Hospital, 54 Shogoin-Kawahara-cho, Sakyo-ku, 606-8507, Kyoto, Japan", 
              "id": "http://www.grid.ac/institutes/grid.411217.0", 
              "name": [
                "Rehabilitation Unit, Kyoto University Hospital, 54 Shogoin-Kawahara-cho, Sakyo-ku, 606-8507, Kyoto, Japan"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Yonezawa", 
            "givenName": "Honami", 
            "id": "sg:person.012022713634.11", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012022713634.11"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Clinical Laboratory Medicine and Center for Research and Application of Cellular Therapy, Kyoto University, Sakyo-ku, Kyoto, Japan", 
              "id": "http://www.grid.ac/institutes/grid.258799.8", 
              "name": [
                "Department of Hematology and Oncology, Graduate School of Medicine, Kyoto University, Sakyo-ku, Kyoto, Japan", 
                "Department of Clinical Laboratory Medicine and Center for Research and Application of Cellular Therapy, Kyoto University, Sakyo-ku, Kyoto, Japan"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Arai", 
            "givenName": "Yasuyuki", 
            "id": "sg:person.0632351344.47", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0632351344.47"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Hematology and Oncology, Graduate School of Medicine, Kyoto University, Sakyo-ku, Kyoto, Japan", 
              "id": "http://www.grid.ac/institutes/grid.258799.8", 
              "name": [
                "Department of Hematology and Oncology, Graduate School of Medicine, Kyoto University, Sakyo-ku, Kyoto, Japan"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Kanda", 
            "givenName": "Junya", 
            "id": "sg:person.01100640630.10", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01100640630.10"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Rehabilitation Unit, Kyoto University Hospital, 54 Shogoin-Kawahara-cho, Sakyo-ku, 606-8507, Kyoto, Japan", 
              "id": "http://www.grid.ac/institutes/grid.411217.0", 
              "name": [
                "Rehabilitation Unit, Kyoto University Hospital, 54 Shogoin-Kawahara-cho, Sakyo-ku, 606-8507, Kyoto, Japan"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Nankaku", 
            "givenName": "Manabu", 
            "id": "sg:person.01142064403.47", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01142064403.47"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Rehabilitation Unit, Kyoto University Hospital, 54 Shogoin-Kawahara-cho, Sakyo-ku, 606-8507, Kyoto, Japan", 
              "id": "http://www.grid.ac/institutes/grid.411217.0", 
              "name": [
                "Rehabilitation Unit, Kyoto University Hospital, 54 Shogoin-Kawahara-cho, Sakyo-ku, 606-8507, Kyoto, Japan"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Ikeguchi", 
            "givenName": "Ryosuke", 
            "id": "sg:person.01142231372.11", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01142231372.11"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Hematology and Oncology, Graduate School of Medicine, Kyoto University, Sakyo-ku, Kyoto, Japan", 
              "id": "http://www.grid.ac/institutes/grid.258799.8", 
              "name": [
                "Department of Hematology and Oncology, Graduate School of Medicine, Kyoto University, Sakyo-ku, Kyoto, Japan"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Takaori-Kondo", 
            "givenName": "Akifumi", 
            "id": "sg:person.0743352217.37", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0743352217.37"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Rehabilitation Unit, Kyoto University Hospital, 54 Shogoin-Kawahara-cho, Sakyo-ku, 606-8507, Kyoto, Japan", 
              "id": "http://www.grid.ac/institutes/grid.411217.0", 
              "name": [
                "Rehabilitation Unit, Kyoto University Hospital, 54 Shogoin-Kawahara-cho, Sakyo-ku, 606-8507, Kyoto, Japan"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Matsuda", 
            "givenName": "Shuichi", 
            "id": "sg:person.01364270222.38", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01364270222.38"
            ], 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "sg:pub.10.1007/s00520-019-05124-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1122523675", 
              "https://doi.org/10.1007/s00520-019-05124-1"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/978-3-319-91287-5_47", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1106526114", 
              "https://doi.org/10.1007/978-3-319-91287-5_47"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/bmt.2015.195", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1047328320", 
              "https://doi.org/10.1038/bmt.2015.195"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/bcj.2011.14", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1052795845", 
              "https://doi.org/10.1038/bcj.2011.14"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00520-017-4036-6", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1100652698", 
              "https://doi.org/10.1007/s00520-017-4036-6"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00520-018-4059-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1100920294", 
              "https://doi.org/10.1007/s00520-018-4059-7"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/bmt.2011.107", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1014012805", 
              "https://doi.org/10.1038/bmt.2011.107"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf03260127", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015754449", 
              "https://doi.org/10.1007/bf03260127"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s11899-019-0494-x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1111399629", 
              "https://doi.org/10.1007/s11899-019-0494-x"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/bmt.2016.58", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1027099511", 
              "https://doi.org/10.1038/bmt.2016.58"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00520-012-1460-5", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1047749985", 
              "https://doi.org/10.1007/s00520-012-1460-5"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00520-011-1156-2", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1011430643", 
              "https://doi.org/10.1007/s00520-011-1156-2"
            ], 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "2021-06-12", 
        "datePublishedReg": "2021-06-12", 
        "description": "PurposeThe purpose of this study was to clarify the independent factors related to patient-reported physical functioning (PF) scores at discharge of patients who underwent allogeneic hematopoietic stem cell transplantation (allo-HSCT).MethodsA total of 103 patients who underwent allo-HSCT were included in this cross-sectional study. As a screening method, a single regression analysis was conducted with the PF domain in the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 at discharge as the dependent variable, and body mass index, adverse events related to HSCT, and objective physical functions as independent variables. Multiple regression analysis was performed with PF as the dependent variable and variables that passed the screening by single regression analysis and confounders as independent variables.ResultsThe mean PF score at discharge of the patients was 76.5 (standard deviation: 15.2). Based on the results of screening by the single regression analysis, length of stay, infections (+\u2009/\u2009\u2212), acute graft-versus-host disease grade, brief fatigue inventory score (BFI), knee extensor strength, and 6-min walk distance (6MWD) were included in the multiple regression analysis. BFI (B\u2009=\u2009\u2009\u2212\u200911.94, p\u2009<\u20090.001) and 6MWD (per 10\u00a0m) (B\u2009=\u20090.56, p\u2009=\u20090.001) were extracted as significant independent variables governing the PF at discharge in the multiple regression model (adjusted R2\u2009=\u20090.59).ConclusionHigher exercise tolerance and lower fatigue in patients who underwent allo-HSCT were associated independently with patient-reported better PF scores at discharge.", 
        "genre": "article", 
        "id": "sg:pub.10.1007/s00520-021-06323-5", 
        "isAccessibleForFree": true, 
        "isPartOf": [
          {
            "id": "sg:journal.1103473", 
            "issn": [
              "0941-4355", 
              "1433-7339"
            ], 
            "name": "Supportive Care in Cancer", 
            "publisher": "Springer Nature", 
            "type": "Periodical"
          }, 
          {
            "issueNumber": "12", 
            "type": "PublicationIssue"
          }, 
          {
            "type": "PublicationVolume", 
            "volumeNumber": "29"
          }
        ], 
        "keywords": [
          "Brief Fatigue Inventory score", 
          "physical functioning scores", 
          "cross-sectional study", 
          "allo-HSCT", 
          "single regression analysis", 
          "functioning scores", 
          "allogeneic hematopoietic stem cell transplantation patients", 
          "allogeneic hematopoietic stem cell transplantation", 
          "regression analysis", 
          "PF scores", 
          "hematopoietic stem cell transplantation patients", 
          "stem cell transplantation patients", 
          "hematopoietic stem cell transplantation", 
          "Life Questionnaire Core 30", 
          "host disease grade", 
          "cell transplantation patients", 
          "stem cell transplantation", 
          "body mass index", 
          "discharge of patients", 
          "knee extensor strength", 
          "length of stay", 
          "objective physical function", 
          "multiple regression analysis", 
          "acute graft", 
          "transplantation patients", 
          "adverse events", 
          "walk distance", 
          "Cancer Quality", 
          "mass index", 
          "cell transplantation", 
          "Core 30", 
          "physical function", 
          "extensor strength", 
          "disease grade", 
          "independent factors", 
          "patients", 
          "significant independent variables", 
          "PurposeThe purpose", 
          "European Organization", 
          "Inventory scores", 
          "PF domain", 
          "scores", 
          "regression models", 
          "independent variables", 
          "analysis of factors", 
          "multiple regression model", 
          "screening method", 
          "dependent variable", 
          "lower fatigue", 
          "HSCT", 
          "discharge", 
          "transplantation", 
          "stay", 
          "ConclusionHigher", 
          "confounders", 
          "graft", 
          "infection", 
          "study", 
          "factors", 
          "treatment", 
          "total", 
          "screening", 
          "grade", 
          "fatigue", 
          "PF", 
          "variables", 
          "index", 
          "analysis", 
          "events", 
          "tolerance", 
          "purpose", 
          "function", 
          "quality", 
          "length", 
          "results", 
          "research", 
          "method", 
          "organization", 
          "model", 
          "domain", 
          "strength", 
          "distance"
        ], 
        "name": "Analysis of factors associated with patient-reported physical functioning scores at discharge of allogeneic hematopoietic stem cell transplantation patients: a cross-sectional study", 
        "pagination": "7569-7576", 
        "productId": [
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1138792434"
            ]
          }, 
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1007/s00520-021-06323-5"
            ]
          }, 
          {
            "name": "pubmed_id", 
            "type": "PropertyValue", 
            "value": [
              "34120260"
            ]
          }
        ], 
        "sameAs": [
          "https://doi.org/10.1007/s00520-021-06323-5", 
          "https://app.dimensions.ai/details/publication/pub.1138792434"
        ], 
        "sdDataset": "articles", 
        "sdDatePublished": "2022-12-01T06:42", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-springernature-scigraph/baseset/20221201/entities/gbq_results/article/article_890.jsonl", 
        "type": "ScholarlyArticle", 
        "url": "https://doi.org/10.1007/s00520-021-06323-5"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00520-021-06323-5'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00520-021-06323-5'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00520-021-06323-5'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00520-021-06323-5'


     

    This table displays all metadata directly associated to this object as RDF triples.

    301 TRIPLES      21 PREDICATES      126 URIs      106 LITERALS      14 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1007/s00520-021-06323-5 schema:about N250028de3539496c90d33a96ab116b38
    2 N435aae24b73f40cc8bff738bff6bb93d
    3 N73b84d8e0d00441f84ac393c62a2921e
    4 Na2b7d47a6df3402b8e6254db8365e166
    5 Nb5fd65621c1443e48552152f5ace83de
    6 Nd4d6265058054b8ab195fc4d76ab1196
    7 Nf80a0d276d0e486b9c64d002c049d140
    8 anzsrc-for:11
    9 anzsrc-for:1117
    10 schema:author Nbf601284e6694555b4660eb3d2df65a4
    11 schema:citation sg:pub.10.1007/978-3-319-91287-5_47
    12 sg:pub.10.1007/bf03260127
    13 sg:pub.10.1007/s00520-011-1156-2
    14 sg:pub.10.1007/s00520-012-1460-5
    15 sg:pub.10.1007/s00520-017-4036-6
    16 sg:pub.10.1007/s00520-018-4059-7
    17 sg:pub.10.1007/s00520-019-05124-1
    18 sg:pub.10.1007/s11899-019-0494-x
    19 sg:pub.10.1038/bcj.2011.14
    20 sg:pub.10.1038/bmt.2011.107
    21 sg:pub.10.1038/bmt.2015.195
    22 sg:pub.10.1038/bmt.2016.58
    23 schema:datePublished 2021-06-12
    24 schema:datePublishedReg 2021-06-12
    25 schema:description PurposeThe purpose of this study was to clarify the independent factors related to patient-reported physical functioning (PF) scores at discharge of patients who underwent allogeneic hematopoietic stem cell transplantation (allo-HSCT).MethodsA total of 103 patients who underwent allo-HSCT were included in this cross-sectional study. As a screening method, a single regression analysis was conducted with the PF domain in the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 at discharge as the dependent variable, and body mass index, adverse events related to HSCT, and objective physical functions as independent variables. Multiple regression analysis was performed with PF as the dependent variable and variables that passed the screening by single regression analysis and confounders as independent variables.ResultsThe mean PF score at discharge of the patients was 76.5 (standard deviation: 15.2). Based on the results of screening by the single regression analysis, length of stay, infections (+ / −), acute graft-versus-host disease grade, brief fatigue inventory score (BFI), knee extensor strength, and 6-min walk distance (6MWD) were included in the multiple regression analysis. BFI (B =  − 11.94, p < 0.001) and 6MWD (per 10 m) (B = 0.56, p = 0.001) were extracted as significant independent variables governing the PF at discharge in the multiple regression model (adjusted R2 = 0.59).ConclusionHigher exercise tolerance and lower fatigue in patients who underwent allo-HSCT were associated independently with patient-reported better PF scores at discharge.
    26 schema:genre article
    27 schema:isAccessibleForFree true
    28 schema:isPartOf N2ca180003a6048d8adf1da94748f4481
    29 Nb5df18fb4ba14c68b1b255617d36b5e0
    30 sg:journal.1103473
    31 schema:keywords Brief Fatigue Inventory score
    32 Cancer Quality
    33 ConclusionHigher
    34 Core 30
    35 European Organization
    36 HSCT
    37 Inventory scores
    38 Life Questionnaire Core 30
    39 PF
    40 PF domain
    41 PF scores
    42 PurposeThe purpose
    43 acute graft
    44 adverse events
    45 allo-HSCT
    46 allogeneic hematopoietic stem cell transplantation
    47 allogeneic hematopoietic stem cell transplantation patients
    48 analysis
    49 analysis of factors
    50 body mass index
    51 cell transplantation
    52 cell transplantation patients
    53 confounders
    54 cross-sectional study
    55 dependent variable
    56 discharge
    57 discharge of patients
    58 disease grade
    59 distance
    60 domain
    61 events
    62 extensor strength
    63 factors
    64 fatigue
    65 function
    66 functioning scores
    67 grade
    68 graft
    69 hematopoietic stem cell transplantation
    70 hematopoietic stem cell transplantation patients
    71 host disease grade
    72 independent factors
    73 independent variables
    74 index
    75 infection
    76 knee extensor strength
    77 length
    78 length of stay
    79 lower fatigue
    80 mass index
    81 method
    82 model
    83 multiple regression analysis
    84 multiple regression model
    85 objective physical function
    86 organization
    87 patients
    88 physical function
    89 physical functioning scores
    90 purpose
    91 quality
    92 regression analysis
    93 regression models
    94 research
    95 results
    96 scores
    97 screening
    98 screening method
    99 significant independent variables
    100 single regression analysis
    101 stay
    102 stem cell transplantation
    103 stem cell transplantation patients
    104 strength
    105 study
    106 tolerance
    107 total
    108 transplantation
    109 transplantation patients
    110 treatment
    111 variables
    112 walk distance
    113 schema:name Analysis of factors associated with patient-reported physical functioning scores at discharge of allogeneic hematopoietic stem cell transplantation patients: a cross-sectional study
    114 schema:pagination 7569-7576
    115 schema:productId N0046ba2da64d491a9ecff59c3ad28c7e
    116 N175b522cb383479b99e8aa8c57d55f7b
    117 N5a21dd4e96ff4759885b386910e2f029
    118 schema:sameAs https://app.dimensions.ai/details/publication/pub.1138792434
    119 https://doi.org/10.1007/s00520-021-06323-5
    120 schema:sdDatePublished 2022-12-01T06:42
    121 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    122 schema:sdPublisher Ne2923ff25bef47d7824f5196826e4540
    123 schema:url https://doi.org/10.1007/s00520-021-06323-5
    124 sgo:license sg:explorer/license/
    125 sgo:sdDataset articles
    126 rdf:type schema:ScholarlyArticle
    127 N0046ba2da64d491a9ecff59c3ad28c7e schema:name doi
    128 schema:value 10.1007/s00520-021-06323-5
    129 rdf:type schema:PropertyValue
    130 N0a975f2acc4c49059e73ba8da39ce0ca rdf:first sg:person.0666225507.36
    131 rdf:rest Nf1c0a5d3c1d741279aba26a559022787
    132 N175b522cb383479b99e8aa8c57d55f7b schema:name dimensions_id
    133 schema:value pub.1138792434
    134 rdf:type schema:PropertyValue
    135 N250028de3539496c90d33a96ab116b38 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    136 schema:name Patient Discharge
    137 rdf:type schema:DefinedTerm
    138 N2ca180003a6048d8adf1da94748f4481 schema:volumeNumber 29
    139 rdf:type schema:PublicationVolume
    140 N4220ec8a836149ee986a2b2e33dfb639 rdf:first sg:person.015117046057.73
    141 rdf:rest Nae930a9d5a9c4c25a5cc06594426d829
    142 N435aae24b73f40cc8bff738bff6bb93d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    143 schema:name Cross-Sectional Studies
    144 rdf:type schema:DefinedTerm
    145 N50ed51b06cd346d7870a9448dc0ee704 rdf:first sg:person.0743352217.37
    146 rdf:rest N92a20986cd2843bc9a29105f7b9daaa6
    147 N53cdfd36222f44ae8630917474a9279d rdf:first sg:person.012131144057.36
    148 rdf:rest N0a975f2acc4c49059e73ba8da39ce0ca
    149 N5a21dd4e96ff4759885b386910e2f029 schema:name pubmed_id
    150 schema:value 34120260
    151 rdf:type schema:PropertyValue
    152 N6d7b771d6f0a47d7ba69d747f2d774f7 rdf:first sg:person.0632351344.47
    153 rdf:rest Na10c349b163346d28bdf0d8b909e20ee
    154 N73b84d8e0d00441f84ac393c62a2921e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    155 schema:name Quality of Life
    156 rdf:type schema:DefinedTerm
    157 N8d3a8513bada44269af233013186c013 rdf:first sg:person.01142064403.47
    158 rdf:rest Nba0477013e2d4a7a806b7d69a8263e9e
    159 N92a20986cd2843bc9a29105f7b9daaa6 rdf:first sg:person.01364270222.38
    160 rdf:rest rdf:nil
    161 Na10c349b163346d28bdf0d8b909e20ee rdf:first sg:person.01100640630.10
    162 rdf:rest N8d3a8513bada44269af233013186c013
    163 Na2b7d47a6df3402b8e6254db8365e166 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    164 schema:name Patient Reported Outcome Measures
    165 rdf:type schema:DefinedTerm
    166 Nae930a9d5a9c4c25a5cc06594426d829 rdf:first sg:person.012022713634.11
    167 rdf:rest N6d7b771d6f0a47d7ba69d747f2d774f7
    168 Nb5df18fb4ba14c68b1b255617d36b5e0 schema:issueNumber 12
    169 rdf:type schema:PublicationIssue
    170 Nb5fd65621c1443e48552152f5ace83de schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    171 schema:name Hematopoietic Stem Cell Transplantation
    172 rdf:type schema:DefinedTerm
    173 Nba0477013e2d4a7a806b7d69a8263e9e rdf:first sg:person.01142231372.11
    174 rdf:rest N50ed51b06cd346d7870a9448dc0ee704
    175 Nbf601284e6694555b4660eb3d2df65a4 rdf:first sg:person.016151633437.69
    176 rdf:rest N53cdfd36222f44ae8630917474a9279d
    177 Nd4d6265058054b8ab195fc4d76ab1196 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    178 schema:name Graft vs Host Disease
    179 rdf:type schema:DefinedTerm
    180 Ne2923ff25bef47d7824f5196826e4540 schema:name Springer Nature - SN SciGraph project
    181 rdf:type schema:Organization
    182 Nf1c0a5d3c1d741279aba26a559022787 rdf:first sg:person.014555237463.36
    183 rdf:rest N4220ec8a836149ee986a2b2e33dfb639
    184 Nf80a0d276d0e486b9c64d002c049d140 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    185 schema:name Humans
    186 rdf:type schema:DefinedTerm
    187 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
    188 schema:name Medical and Health Sciences
    189 rdf:type schema:DefinedTerm
    190 anzsrc-for:1117 schema:inDefinedTermSet anzsrc-for:
    191 schema:name Public Health and Health Services
    192 rdf:type schema:DefinedTerm
    193 sg:journal.1103473 schema:issn 0941-4355
    194 1433-7339
    195 schema:name Supportive Care in Cancer
    196 schema:publisher Springer Nature
    197 rdf:type schema:Periodical
    198 sg:person.01100640630.10 schema:affiliation grid-institutes:grid.258799.8
    199 schema:familyName Kanda
    200 schema:givenName Junya
    201 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01100640630.10
    202 rdf:type schema:Person
    203 sg:person.01142064403.47 schema:affiliation grid-institutes:grid.411217.0
    204 schema:familyName Nankaku
    205 schema:givenName Manabu
    206 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01142064403.47
    207 rdf:type schema:Person
    208 sg:person.01142231372.11 schema:affiliation grid-institutes:grid.411217.0
    209 schema:familyName Ikeguchi
    210 schema:givenName Ryosuke
    211 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01142231372.11
    212 rdf:type schema:Person
    213 sg:person.012022713634.11 schema:affiliation grid-institutes:grid.411217.0
    214 schema:familyName Yonezawa
    215 schema:givenName Honami
    216 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012022713634.11
    217 rdf:type schema:Person
    218 sg:person.012131144057.36 schema:affiliation grid-institutes:grid.411217.0
    219 schema:familyName Hamada
    220 schema:givenName Ryota
    221 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012131144057.36
    222 rdf:type schema:Person
    223 sg:person.01364270222.38 schema:affiliation grid-institutes:grid.411217.0
    224 schema:familyName Matsuda
    225 schema:givenName Shuichi
    226 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01364270222.38
    227 rdf:type schema:Person
    228 sg:person.014555237463.36 schema:affiliation grid-institutes:grid.411217.0
    229 schema:familyName Miyasaka
    230 schema:givenName Junsuke
    231 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014555237463.36
    232 rdf:type schema:Person
    233 sg:person.015117046057.73 schema:affiliation grid-institutes:grid.411217.0
    234 schema:familyName Yoshida
    235 schema:givenName Michiko
    236 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015117046057.73
    237 rdf:type schema:Person
    238 sg:person.016151633437.69 schema:affiliation grid-institutes:grid.411217.0
    239 schema:familyName Murao
    240 schema:givenName Masanobu
    241 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016151633437.69
    242 rdf:type schema:Person
    243 sg:person.0632351344.47 schema:affiliation grid-institutes:grid.258799.8
    244 schema:familyName Arai
    245 schema:givenName Yasuyuki
    246 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0632351344.47
    247 rdf:type schema:Person
    248 sg:person.0666225507.36 schema:affiliation grid-institutes:grid.258799.8
    249 schema:familyName Kondo
    250 schema:givenName Tadakazu
    251 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0666225507.36
    252 rdf:type schema:Person
    253 sg:person.0743352217.37 schema:affiliation grid-institutes:grid.258799.8
    254 schema:familyName Takaori-Kondo
    255 schema:givenName Akifumi
    256 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0743352217.37
    257 rdf:type schema:Person
    258 sg:pub.10.1007/978-3-319-91287-5_47 schema:sameAs https://app.dimensions.ai/details/publication/pub.1106526114
    259 https://doi.org/10.1007/978-3-319-91287-5_47
    260 rdf:type schema:CreativeWork
    261 sg:pub.10.1007/bf03260127 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015754449
    262 https://doi.org/10.1007/bf03260127
    263 rdf:type schema:CreativeWork
    264 sg:pub.10.1007/s00520-011-1156-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011430643
    265 https://doi.org/10.1007/s00520-011-1156-2
    266 rdf:type schema:CreativeWork
    267 sg:pub.10.1007/s00520-012-1460-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047749985
    268 https://doi.org/10.1007/s00520-012-1460-5
    269 rdf:type schema:CreativeWork
    270 sg:pub.10.1007/s00520-017-4036-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1100652698
    271 https://doi.org/10.1007/s00520-017-4036-6
    272 rdf:type schema:CreativeWork
    273 sg:pub.10.1007/s00520-018-4059-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1100920294
    274 https://doi.org/10.1007/s00520-018-4059-7
    275 rdf:type schema:CreativeWork
    276 sg:pub.10.1007/s00520-019-05124-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1122523675
    277 https://doi.org/10.1007/s00520-019-05124-1
    278 rdf:type schema:CreativeWork
    279 sg:pub.10.1007/s11899-019-0494-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1111399629
    280 https://doi.org/10.1007/s11899-019-0494-x
    281 rdf:type schema:CreativeWork
    282 sg:pub.10.1038/bcj.2011.14 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052795845
    283 https://doi.org/10.1038/bcj.2011.14
    284 rdf:type schema:CreativeWork
    285 sg:pub.10.1038/bmt.2011.107 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014012805
    286 https://doi.org/10.1038/bmt.2011.107
    287 rdf:type schema:CreativeWork
    288 sg:pub.10.1038/bmt.2015.195 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047328320
    289 https://doi.org/10.1038/bmt.2015.195
    290 rdf:type schema:CreativeWork
    291 sg:pub.10.1038/bmt.2016.58 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027099511
    292 https://doi.org/10.1038/bmt.2016.58
    293 rdf:type schema:CreativeWork
    294 grid-institutes:grid.258799.8 schema:alternateName Department of Clinical Laboratory Medicine and Center for Research and Application of Cellular Therapy, Kyoto University, Sakyo-ku, Kyoto, Japan
    295 Department of Hematology and Oncology, Graduate School of Medicine, Kyoto University, Sakyo-ku, Kyoto, Japan
    296 schema:name Department of Clinical Laboratory Medicine and Center for Research and Application of Cellular Therapy, Kyoto University, Sakyo-ku, Kyoto, Japan
    297 Department of Hematology and Oncology, Graduate School of Medicine, Kyoto University, Sakyo-ku, Kyoto, Japan
    298 rdf:type schema:Organization
    299 grid-institutes:grid.411217.0 schema:alternateName Rehabilitation Unit, Kyoto University Hospital, 54 Shogoin-Kawahara-cho, Sakyo-ku, 606-8507, Kyoto, Japan
    300 schema:name Rehabilitation Unit, Kyoto University Hospital, 54 Shogoin-Kawahara-cho, Sakyo-ku, 606-8507, Kyoto, Japan
    301 rdf:type schema:Organization
     




    Preview window. Press ESC to close (or click here)


    ...