Safety of oral hydration after cisplatin infusion in an outpatient lung cancer unit View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2019-05

AUTHORS

Florent Puisset, Laurence Bigay-Game, Marie Noëlle Paludetto, Audrey Martel, Sophie Perriat, Audrey Rabeau, Jean Marie Canonge, Julien Mazieres

ABSTRACT

PURPOSE: Hydration is needed before and after cisplatin infusion for reducing the risk of nephrotoxicity. Even though there is no standard regimen, patients receive mostly intravenous hydration before and after cisplatin leading hospitalization during at least one night. Since the feasibility has been published, oral hydration after cisplatin was implemented in our practice. The safety of this new way of hydration needs to be assessed in clinical practice. METHODS: We collected medical records from patients treated by cisplatin for lung cancer in our unit between 2010 and 2016. We retrospectively analyzed the incidence of cisplatin induced nephrotoxicity between after and before the change of hydration regimen. RESULTS: Our patient cohort included 241 patients hydrated by intravenous regimen (IV/IV group) and 276 patient hydrated by intravenous and oral regimen (IV/PO group). Grade ≥ 1 nephrotoxicity occurred in 39.4 and 25.7% in the IV/IV and IV/PO groups respectively (p = 0.001). Age over 70 at baseline was a predictive factor for nephrotoxicity, but not estimated glomerular filtration rate nor cisplatin-associated drugs. After a multivariate analysis, age remained a predictive factor for nephrotoxicity and IV/PO hydration associated with a decrease in nephrotoxic risk. CONCLUSION: The implementation of oral hydration in our practice was not associated with an increase in nephrotoxicity. Our observation based on large data from clinical practice shows that oral hydration after cisplatin is safe. More... »

PAGES

1-8

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00520-018-4415-7

DOI

http://dx.doi.org/10.1007/s00520-018-4415-7

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1106156549

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30120556


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Institut Claudius Regaud", 
          "id": "https://www.grid.ac/institutes/grid.417829.1", 
          "name": [
            "Pharmacy department IUCT (Institut Universitaire du Cancer) Oncopole, Institut Claudius Regaud, Toulouse, France", 
            "CRCT (Cancer Research Centre of Toulouse), Universit\u00e9 de Toulouse, Inserm UMR 1037, Universit\u00e9 Paul Sabatier, 31059, Toulouse Cedex 9, France", 
            "Pharmacie, Institut Universitaire du Cancer Toulousain-Oncopole, 1 Avenue Ir\u00e8ne Joliot-Curie, 31059, Toulouse Cedex 9, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Puisset", 
        "givenName": "Florent", 
        "id": "sg:person.01154017640.30", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01154017640.30"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Centre Hospitalier Universitaire de Toulouse", 
          "id": "https://www.grid.ac/institutes/grid.411175.7", 
          "name": [
            "Thoracic Oncology Department, Larrey Hospital, University Hospital Toulouse, Toulouse, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Bigay-Game", 
        "givenName": "Laurence", 
        "id": "sg:person.01247665100.49", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01247665100.49"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institut Claudius Regaud", 
          "id": "https://www.grid.ac/institutes/grid.417829.1", 
          "name": [
            "Pharmacy department IUCT (Institut Universitaire du Cancer) Oncopole, Institut Claudius Regaud, Toulouse, France", 
            "CRCT (Cancer Research Centre of Toulouse), Universit\u00e9 de Toulouse, Inserm UMR 1037, Universit\u00e9 Paul Sabatier, 31059, Toulouse Cedex 9, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Paludetto", 
        "givenName": "Marie No\u00eblle", 
        "id": "sg:person.0665671770.68", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0665671770.68"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institut Claudius Regaud", 
          "id": "https://www.grid.ac/institutes/grid.417829.1", 
          "name": [
            "Pharmacy department IUCT (Institut Universitaire du Cancer) Oncopole, Institut Claudius Regaud, Toulouse, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Martel", 
        "givenName": "Audrey", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Centre Hospitalier Universitaire de Toulouse", 
          "id": "https://www.grid.ac/institutes/grid.411175.7", 
          "name": [
            "Pharmacy department IUCT (Institut Universitaire du Cancer) Oncopole, University Hospital Toulouse, Toulouse, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Perriat", 
        "givenName": "Sophie", 
        "id": "sg:person.07610551733.51", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07610551733.51"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Centre Hospitalier Universitaire de Toulouse", 
          "id": "https://www.grid.ac/institutes/grid.411175.7", 
          "name": [
            "Thoracic Oncology Department, Larrey Hospital, University Hospital Toulouse, Toulouse, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Rabeau", 
        "givenName": "Audrey", 
        "id": "sg:person.015677260711.19", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015677260711.19"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Centre Hospitalier Universitaire de Toulouse", 
          "id": "https://www.grid.ac/institutes/grid.411175.7", 
          "name": [
            "Pharmacy department IUCT (Institut Universitaire du Cancer) Oncopole, University Hospital Toulouse, Toulouse, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Canonge", 
        "givenName": "Jean Marie", 
        "id": "sg:person.0622072064.23", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0622072064.23"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Paul Sabatier University", 
          "id": "https://www.grid.ac/institutes/grid.15781.3a", 
          "name": [
            "Thoracic Oncology Department, Larrey Hospital, University Hospital Toulouse, Toulouse, France", 
            "Universit\u00e9 Paul Sabatier, Toulouse, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Mazieres", 
        "givenName": "Julien", 
        "id": "sg:person.01256505713.01", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01256505713.01"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1093/jjco/hyt128", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000564964"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0002-9343(78)90825-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002090217"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1365-2354.2011.01284.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003432630"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0895-4356(88)90164-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011323639"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2009.23.5622", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012862395"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s12885-016-2271-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018065825", 
          "https://doi.org/10.1186/s12885-016-2271-8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s12885-016-2271-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018065825", 
          "https://doi.org/10.1186/s12885-016-2271-8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00520-016-3512-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019714388", 
          "https://doi.org/10.1007/s00520-016-3512-8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00520-016-3512-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019714388", 
          "https://doi.org/10.1007/s00520-016-3512-8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/bjc.1986.147", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022790208", 
          "https://doi.org/10.1038/bjc.1986.147"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/bjc.1986.147", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022790208", 
          "https://doi.org/10.1038/bjc.1986.147"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1155/2014/767652", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023957722"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/jjco/hyt122", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026212157"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s40780-016-0041-z", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028325415", 
          "https://doi.org/10.1186/s40780-016-0041-z"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s002800050661", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028812650", 
          "https://doi.org/10.1007/s002800050661"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/cc2872", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031071552", 
          "https://doi.org/10.1186/cc2872"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/cc2872", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031071552", 
          "https://doi.org/10.1186/cc2872"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1517/14656566.2014.957180", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031191846"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.lungcan.2015.05.005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032599322"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.5049/ebp.2014.12.2.55", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033288694"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00280-008-0711-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033938765", 
          "https://doi.org/10.1007/s00280-008-0711-0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00280-008-0711-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033938765", 
          "https://doi.org/10.1007/s00280-008-0711-0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3390/toxins2112490", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036992715"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10147-015-0860-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037887700", 
          "https://doi.org/10.1007/s10147-015-0860-1"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2015.62.1342", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043437482"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ejca.2008.08.005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044303559"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.ki.5002786", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044663570", 
          "https://doi.org/10.1038/sj.ki.5002786"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/jjco/hyw097", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1059803117"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.7326/0003-4819-130-6-199903160-00002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1073703194"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1177/030089160709300205", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1077429754"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1177/030089160709300205", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1077429754"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1684/bdc.2012.1555", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1078537947"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.1987.5.2.304", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1079961774"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ejmech.2017.07.063", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1090956681"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s13318-017-0436-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1091770573", 
          "https://doi.org/10.1007/s13318-017-0436-8"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2019-05", 
    "datePublishedReg": "2019-05-01", 
    "description": "PURPOSE: Hydration is needed before and after cisplatin infusion for reducing the risk of nephrotoxicity. Even though there is no standard regimen, patients receive mostly intravenous hydration before and after cisplatin leading hospitalization during at least one night. Since the feasibility has been published, oral hydration after cisplatin was implemented in our practice. The safety of this new way of hydration needs to be assessed in clinical practice.\nMETHODS: We collected medical records from patients treated by cisplatin for lung cancer in our unit between 2010 and 2016. We retrospectively analyzed the incidence of cisplatin induced nephrotoxicity between after and before the change of hydration regimen.\nRESULTS: Our patient cohort included 241 patients hydrated by intravenous regimen (IV/IV group) and 276 patient hydrated by intravenous and oral regimen (IV/PO group). Grade \u2265\u00a01 nephrotoxicity occurred in 39.4 and 25.7% in the IV/IV and IV/PO groups respectively (p\u2009=\u20090.001). Age over 70 at baseline was a predictive factor for nephrotoxicity, but not estimated glomerular filtration rate nor cisplatin-associated drugs. After a multivariate analysis, age remained a predictive factor for nephrotoxicity and IV/PO hydration associated with a decrease in nephrotoxic risk.\nCONCLUSION: The implementation of oral hydration in our practice was not associated with an increase in nephrotoxicity. Our observation based on large data from clinical practice shows that oral hydration after cisplatin is safe.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s00520-018-4415-7", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1103473", 
        "issn": [
          "0941-4355", 
          "1433-7339"
        ], 
        "name": "Supportive Care in Cancer", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "5", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "27"
      }
    ], 
    "name": "Safety of oral hydration after cisplatin infusion in an outpatient lung cancer unit", 
    "pagination": "1-8", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "9f60a661daf449c6614c002053e4d699a67c45e067089b16db2efef7ba8e11b9"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "30120556"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "9302957"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s00520-018-4415-7"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1106156549"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s00520-018-4415-7", 
      "https://app.dimensions.ai/details/publication/pub.1106156549"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T14:29", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000373_0000000373/records_13084_00000002.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1007%2Fs00520-018-4415-7"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00520-018-4415-7'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00520-018-4415-7'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00520-018-4415-7'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00520-018-4415-7'


 

This table displays all metadata directly associated to this object as RDF triples.

224 TRIPLES      21 PREDICATES      58 URIs      21 LITERALS      9 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s00520-018-4415-7 schema:about anzsrc-for:11
2 anzsrc-for:1103
3 schema:author N6e86965271954f05a6920a1631ee2dcb
4 schema:citation sg:pub.10.1007/s00280-008-0711-0
5 sg:pub.10.1007/s002800050661
6 sg:pub.10.1007/s00520-016-3512-8
7 sg:pub.10.1007/s10147-015-0860-1
8 sg:pub.10.1007/s13318-017-0436-8
9 sg:pub.10.1038/bjc.1986.147
10 sg:pub.10.1038/sj.ki.5002786
11 sg:pub.10.1186/cc2872
12 sg:pub.10.1186/s12885-016-2271-8
13 sg:pub.10.1186/s40780-016-0041-z
14 https://doi.org/10.1016/0002-9343(78)90825-2
15 https://doi.org/10.1016/0895-4356(88)90164-3
16 https://doi.org/10.1016/j.ejca.2008.08.005
17 https://doi.org/10.1016/j.ejmech.2017.07.063
18 https://doi.org/10.1016/j.lungcan.2015.05.005
19 https://doi.org/10.1093/jjco/hyt122
20 https://doi.org/10.1093/jjco/hyt128
21 https://doi.org/10.1093/jjco/hyw097
22 https://doi.org/10.1111/j.1365-2354.2011.01284.x
23 https://doi.org/10.1155/2014/767652
24 https://doi.org/10.1177/030089160709300205
25 https://doi.org/10.1200/jco.1987.5.2.304
26 https://doi.org/10.1200/jco.2009.23.5622
27 https://doi.org/10.1200/jco.2015.62.1342
28 https://doi.org/10.1517/14656566.2014.957180
29 https://doi.org/10.1684/bdc.2012.1555
30 https://doi.org/10.3390/toxins2112490
31 https://doi.org/10.5049/ebp.2014.12.2.55
32 https://doi.org/10.7326/0003-4819-130-6-199903160-00002
33 schema:datePublished 2019-05
34 schema:datePublishedReg 2019-05-01
35 schema:description PURPOSE: Hydration is needed before and after cisplatin infusion for reducing the risk of nephrotoxicity. Even though there is no standard regimen, patients receive mostly intravenous hydration before and after cisplatin leading hospitalization during at least one night. Since the feasibility has been published, oral hydration after cisplatin was implemented in our practice. The safety of this new way of hydration needs to be assessed in clinical practice. METHODS: We collected medical records from patients treated by cisplatin for lung cancer in our unit between 2010 and 2016. We retrospectively analyzed the incidence of cisplatin induced nephrotoxicity between after and before the change of hydration regimen. RESULTS: Our patient cohort included 241 patients hydrated by intravenous regimen (IV/IV group) and 276 patient hydrated by intravenous and oral regimen (IV/PO group). Grade ≥ 1 nephrotoxicity occurred in 39.4 and 25.7% in the IV/IV and IV/PO groups respectively (p = 0.001). Age over 70 at baseline was a predictive factor for nephrotoxicity, but not estimated glomerular filtration rate nor cisplatin-associated drugs. After a multivariate analysis, age remained a predictive factor for nephrotoxicity and IV/PO hydration associated with a decrease in nephrotoxic risk. CONCLUSION: The implementation of oral hydration in our practice was not associated with an increase in nephrotoxicity. Our observation based on large data from clinical practice shows that oral hydration after cisplatin is safe.
36 schema:genre research_article
37 schema:inLanguage en
38 schema:isAccessibleForFree false
39 schema:isPartOf N63e585e2f7384dd69395abdfb345612a
40 Nae3b06065d5d4819beebc92d9eaa03b1
41 sg:journal.1103473
42 schema:name Safety of oral hydration after cisplatin infusion in an outpatient lung cancer unit
43 schema:pagination 1-8
44 schema:productId N019d03f0957d4f649976578cf17485dd
45 N444f9ce9a4de446797b93e6f36afd6ea
46 N81a4524e60ea42038f353545131e532c
47 Neb0b3d2dad3c449ba1e9fbadf012b92d
48 Nfb9f8ef933644bcab8b52b14d420457f
49 schema:sameAs https://app.dimensions.ai/details/publication/pub.1106156549
50 https://doi.org/10.1007/s00520-018-4415-7
51 schema:sdDatePublished 2019-04-11T14:29
52 schema:sdLicense https://scigraph.springernature.com/explorer/license/
53 schema:sdPublisher N295c804f76bc4f98ae38cdd96cbb3679
54 schema:url http://link.springer.com/10.1007%2Fs00520-018-4415-7
55 sgo:license sg:explorer/license/
56 sgo:sdDataset articles
57 rdf:type schema:ScholarlyArticle
58 N019d03f0957d4f649976578cf17485dd schema:name nlm_unique_id
59 schema:value 9302957
60 rdf:type schema:PropertyValue
61 N11ddf9e764b54dd8bed98a65c83b6cec rdf:first Ne735d5e7e1f44ecfb126e7281d041b0d
62 rdf:rest N3ca362bb8cbe48fc939100d3ffed1e06
63 N143b9a6da72049519e928ad61049f7b8 rdf:first sg:person.015677260711.19
64 rdf:rest N8eceb3d8b5844e2daa2ea0bccd13485a
65 N295c804f76bc4f98ae38cdd96cbb3679 schema:name Springer Nature - SN SciGraph project
66 rdf:type schema:Organization
67 N3ca362bb8cbe48fc939100d3ffed1e06 rdf:first sg:person.07610551733.51
68 rdf:rest N143b9a6da72049519e928ad61049f7b8
69 N444f9ce9a4de446797b93e6f36afd6ea schema:name dimensions_id
70 schema:value pub.1106156549
71 rdf:type schema:PropertyValue
72 N63e585e2f7384dd69395abdfb345612a schema:volumeNumber 27
73 rdf:type schema:PublicationVolume
74 N6e86965271954f05a6920a1631ee2dcb rdf:first sg:person.01154017640.30
75 rdf:rest Nceb1c095f19a42a780ab6ced40647cab
76 N784d3b7cce90403797674b06ce671985 rdf:first sg:person.01256505713.01
77 rdf:rest rdf:nil
78 N81a4524e60ea42038f353545131e532c schema:name readcube_id
79 schema:value 9f60a661daf449c6614c002053e4d699a67c45e067089b16db2efef7ba8e11b9
80 rdf:type schema:PropertyValue
81 N8eceb3d8b5844e2daa2ea0bccd13485a rdf:first sg:person.0622072064.23
82 rdf:rest N784d3b7cce90403797674b06ce671985
83 N9ef9356c6db74b95a358c4e83e07d9d7 rdf:first sg:person.0665671770.68
84 rdf:rest N11ddf9e764b54dd8bed98a65c83b6cec
85 Nae3b06065d5d4819beebc92d9eaa03b1 schema:issueNumber 5
86 rdf:type schema:PublicationIssue
87 Nceb1c095f19a42a780ab6ced40647cab rdf:first sg:person.01247665100.49
88 rdf:rest N9ef9356c6db74b95a358c4e83e07d9d7
89 Ne735d5e7e1f44ecfb126e7281d041b0d schema:affiliation https://www.grid.ac/institutes/grid.417829.1
90 schema:familyName Martel
91 schema:givenName Audrey
92 rdf:type schema:Person
93 Neb0b3d2dad3c449ba1e9fbadf012b92d schema:name pubmed_id
94 schema:value 30120556
95 rdf:type schema:PropertyValue
96 Nfb9f8ef933644bcab8b52b14d420457f schema:name doi
97 schema:value 10.1007/s00520-018-4415-7
98 rdf:type schema:PropertyValue
99 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
100 schema:name Medical and Health Sciences
101 rdf:type schema:DefinedTerm
102 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
103 schema:name Clinical Sciences
104 rdf:type schema:DefinedTerm
105 sg:journal.1103473 schema:issn 0941-4355
106 1433-7339
107 schema:name Supportive Care in Cancer
108 rdf:type schema:Periodical
109 sg:person.01154017640.30 schema:affiliation https://www.grid.ac/institutes/grid.417829.1
110 schema:familyName Puisset
111 schema:givenName Florent
112 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01154017640.30
113 rdf:type schema:Person
114 sg:person.01247665100.49 schema:affiliation https://www.grid.ac/institutes/grid.411175.7
115 schema:familyName Bigay-Game
116 schema:givenName Laurence
117 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01247665100.49
118 rdf:type schema:Person
119 sg:person.01256505713.01 schema:affiliation https://www.grid.ac/institutes/grid.15781.3a
120 schema:familyName Mazieres
121 schema:givenName Julien
122 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01256505713.01
123 rdf:type schema:Person
124 sg:person.015677260711.19 schema:affiliation https://www.grid.ac/institutes/grid.411175.7
125 schema:familyName Rabeau
126 schema:givenName Audrey
127 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015677260711.19
128 rdf:type schema:Person
129 sg:person.0622072064.23 schema:affiliation https://www.grid.ac/institutes/grid.411175.7
130 schema:familyName Canonge
131 schema:givenName Jean Marie
132 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0622072064.23
133 rdf:type schema:Person
134 sg:person.0665671770.68 schema:affiliation https://www.grid.ac/institutes/grid.417829.1
135 schema:familyName Paludetto
136 schema:givenName Marie Noëlle
137 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0665671770.68
138 rdf:type schema:Person
139 sg:person.07610551733.51 schema:affiliation https://www.grid.ac/institutes/grid.411175.7
140 schema:familyName Perriat
141 schema:givenName Sophie
142 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07610551733.51
143 rdf:type schema:Person
144 sg:pub.10.1007/s00280-008-0711-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033938765
145 https://doi.org/10.1007/s00280-008-0711-0
146 rdf:type schema:CreativeWork
147 sg:pub.10.1007/s002800050661 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028812650
148 https://doi.org/10.1007/s002800050661
149 rdf:type schema:CreativeWork
150 sg:pub.10.1007/s00520-016-3512-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019714388
151 https://doi.org/10.1007/s00520-016-3512-8
152 rdf:type schema:CreativeWork
153 sg:pub.10.1007/s10147-015-0860-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037887700
154 https://doi.org/10.1007/s10147-015-0860-1
155 rdf:type schema:CreativeWork
156 sg:pub.10.1007/s13318-017-0436-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1091770573
157 https://doi.org/10.1007/s13318-017-0436-8
158 rdf:type schema:CreativeWork
159 sg:pub.10.1038/bjc.1986.147 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022790208
160 https://doi.org/10.1038/bjc.1986.147
161 rdf:type schema:CreativeWork
162 sg:pub.10.1038/sj.ki.5002786 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044663570
163 https://doi.org/10.1038/sj.ki.5002786
164 rdf:type schema:CreativeWork
165 sg:pub.10.1186/cc2872 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031071552
166 https://doi.org/10.1186/cc2872
167 rdf:type schema:CreativeWork
168 sg:pub.10.1186/s12885-016-2271-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018065825
169 https://doi.org/10.1186/s12885-016-2271-8
170 rdf:type schema:CreativeWork
171 sg:pub.10.1186/s40780-016-0041-z schema:sameAs https://app.dimensions.ai/details/publication/pub.1028325415
172 https://doi.org/10.1186/s40780-016-0041-z
173 rdf:type schema:CreativeWork
174 https://doi.org/10.1016/0002-9343(78)90825-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002090217
175 rdf:type schema:CreativeWork
176 https://doi.org/10.1016/0895-4356(88)90164-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011323639
177 rdf:type schema:CreativeWork
178 https://doi.org/10.1016/j.ejca.2008.08.005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044303559
179 rdf:type schema:CreativeWork
180 https://doi.org/10.1016/j.ejmech.2017.07.063 schema:sameAs https://app.dimensions.ai/details/publication/pub.1090956681
181 rdf:type schema:CreativeWork
182 https://doi.org/10.1016/j.lungcan.2015.05.005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032599322
183 rdf:type schema:CreativeWork
184 https://doi.org/10.1093/jjco/hyt122 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026212157
185 rdf:type schema:CreativeWork
186 https://doi.org/10.1093/jjco/hyt128 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000564964
187 rdf:type schema:CreativeWork
188 https://doi.org/10.1093/jjco/hyw097 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059803117
189 rdf:type schema:CreativeWork
190 https://doi.org/10.1111/j.1365-2354.2011.01284.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1003432630
191 rdf:type schema:CreativeWork
192 https://doi.org/10.1155/2014/767652 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023957722
193 rdf:type schema:CreativeWork
194 https://doi.org/10.1177/030089160709300205 schema:sameAs https://app.dimensions.ai/details/publication/pub.1077429754
195 rdf:type schema:CreativeWork
196 https://doi.org/10.1200/jco.1987.5.2.304 schema:sameAs https://app.dimensions.ai/details/publication/pub.1079961774
197 rdf:type schema:CreativeWork
198 https://doi.org/10.1200/jco.2009.23.5622 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012862395
199 rdf:type schema:CreativeWork
200 https://doi.org/10.1200/jco.2015.62.1342 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043437482
201 rdf:type schema:CreativeWork
202 https://doi.org/10.1517/14656566.2014.957180 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031191846
203 rdf:type schema:CreativeWork
204 https://doi.org/10.1684/bdc.2012.1555 schema:sameAs https://app.dimensions.ai/details/publication/pub.1078537947
205 rdf:type schema:CreativeWork
206 https://doi.org/10.3390/toxins2112490 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036992715
207 rdf:type schema:CreativeWork
208 https://doi.org/10.5049/ebp.2014.12.2.55 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033288694
209 rdf:type schema:CreativeWork
210 https://doi.org/10.7326/0003-4819-130-6-199903160-00002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1073703194
211 rdf:type schema:CreativeWork
212 https://www.grid.ac/institutes/grid.15781.3a schema:alternateName Paul Sabatier University
213 schema:name Thoracic Oncology Department, Larrey Hospital, University Hospital Toulouse, Toulouse, France
214 Université Paul Sabatier, Toulouse, France
215 rdf:type schema:Organization
216 https://www.grid.ac/institutes/grid.411175.7 schema:alternateName Centre Hospitalier Universitaire de Toulouse
217 schema:name Pharmacy department IUCT (Institut Universitaire du Cancer) Oncopole, University Hospital Toulouse, Toulouse, France
218 Thoracic Oncology Department, Larrey Hospital, University Hospital Toulouse, Toulouse, France
219 rdf:type schema:Organization
220 https://www.grid.ac/institutes/grid.417829.1 schema:alternateName Institut Claudius Regaud
221 schema:name CRCT (Cancer Research Centre of Toulouse), Université de Toulouse, Inserm UMR 1037, Université Paul Sabatier, 31059, Toulouse Cedex 9, France
222 Pharmacie, Institut Universitaire du Cancer Toulousain-Oncopole, 1 Avenue Irène Joliot-Curie, 31059, Toulouse Cedex 9, France
223 Pharmacy department IUCT (Institut Universitaire du Cancer) Oncopole, Institut Claudius Regaud, Toulouse, France
224 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...