Predictors of anxiety and depression in people with colorectal cancer View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2014-02

AUTHORS

Nicola M. Gray, Susan J. Hall, Susan Browne, Marie Johnston, Amanda J. Lee, Una Macleod, Elizabeth D. Mitchell, Leslie Samuel, Neil C. Campbell

ABSTRACT

BACKGROUND: People living with colorectal cancer are at risk of anxiety and depression. We investigated what factors were most highly associated with these. METHODS: Four hundred and ninety-six people with colorectal cancer completed the Hospital Anxiety and Depression Scale (HADS). Data on functioning, symptoms, illness perceptions and social difficulties were collected by questionnaire. Case-note-identified disease, treatment and co-morbidity data were recorded. Multiple logistic regression identified factors independently predictive of anxiety and depression caseness. RESULTS: Self-reported history of anxiety/depression predicted anxiety but not depression caseness. Depression caseness predicted anxiety caseness (p = 0.043), as did poorer self-reported cognitive functioning (p = 0.001), dyspnoea (p = 0.015) or diarrhoea (p = 0.021), reporting a high negative life and emotional impact (p < 0.001) and having difficulties with finance (p = 0.007). Having neo-adjuvant radiotherapy increased the odds of depression caseness (p = 0.007), as did poorer physical (p = 0.007), cognitive (p < 0.001) and social (p < 0.001) functioning, having constipation (p = 0.011), reporting a high negative life and emotional impact (p < 0.001), having difficulties with personal care (p = 0.022) and communicating with others (p = 0.014). CONCLUSION: Levels of anxiety caseness were similar to those of non-clinical samples, but depression caseness was higher, particularly in those who had received neo-adjuvant radiotherapy. Most factors associated with possible or probable depression may be modified with appropriate intervention. More... »

PAGES

307-314

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  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s00520-013-1963-8

    DOI

    http://dx.doi.org/10.1007/s00520-013-1963-8

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1017124641

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/24077745


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