Cryptogenic organizing pneumonia due to amiodarone: long-term follow-up after corticosteroid treatment View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2010-08-02

AUTHORS

Katja Schindler, Wolfgang Schima, Josef F. Kaliman

ABSTRACT

Cryptogenic organizing pneumonia (formerly known as bronchiolitis obliterans organizing pneumonia) is a clinicopathological entity with characteristical radiographic findings such as bilateral, asymmetrical, sometimes migrating, patchy infiltrates in chest radiograph and ground-glass opacities in computed tomography. The disease has been observed in the context of gastrointestinal disorders, certain lung infections, autoimmune-mediated diseases (such as Wegener granulomatosis), inhalation of toxic fumes, bone marrow transplantation and administration of drugs. The benzofuran amiodarone, a commonly used antiarrythmic drug for atrial fibrillation, can exhibit several pulmonary adverse effects, amongst them cryptogenic organizing pneumonia as a rarely diagnosed and published one. We report a case of cryptogenic organizing pneumonia secondary to amiodarone treatment, its clinical course with significant improvement of clinical symptoms within a few days after discontinuation of amiodarone treatment and administration of corticosteroids. Also the infiltrations found in chest X-ray and computed tomography responded well and showed remarkable resolution tendency quickly. During 5 months of corticoid therapy pulmonary abnormalities gradually resolved almost completely and remained equal during the 8 months follow-up after corticoid termination. More... »

PAGES

511-514

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00508-010-1412-3

DOI

http://dx.doi.org/10.1007/s00508-010-1412-3

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1027784722

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/20668958


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