Organic hyperinsulinism and endoscopic surgery View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2005-01-01

AUTHORS

Klaus Kaczirek, Reza Asari, Christian Scheuba, Bruno Niederle

ABSTRACT

BACKGROUND: Experience with minimally invasive surgery for organic hyperinsulinism is limited. No criteria for patient selection with special regard to sporadic, hereditary, multiple and malignant tumors have been defined. METHODS: The estimated success rate of endoscopic surgery was retrospectively calculated by analysing 34 consecutive patients with organic hyperinsulinism operated on by open surgery. A literature search was undertaken to better define indications for endoscopic procedures. Differences in postoperative outcome (morbidity) between endoscopic and open procedures were analysed. RESULTS: Twenty-eight of 31 patients (90%) with solitary insulinomas and one of three patients with multiple insulinomas were correctly localized preoperatively. Twenty-six enucleations (76%) and eight distal resections (24%) including one endoscopic tail resection were performed. Theoretically only 14 out of 34 patients (41%) would have been suitable for endoscopic surgery (8 enucleations and 6 patients for distal resections which were enucleated using an open approach). Pancreatic fistulas were documented in three patients (9%). Reviewing 34 publications, 49 enucleations, 36 distal resections and 15 conversions to open surgery were performed, showing a higher proportion of distal resections in endoscopic surgery. The spleen was preserved in 88% of cases. Fourteen fistulas occurred after enucleations. CONCLUSIONS: Only solitary insulinomas localized in the pancreatic tail or superficially in the body or head may be candidates for endoscopic procedures. Patients with multiple insulinomas, MEN-1 syndrome or malignancy should undergo open surgery. More... »

PAGES

19-25

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00508-004-0287-6

DOI

http://dx.doi.org/10.1007/s00508-004-0287-6

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1040733162

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/15986586


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Endoscopy, Digestive System", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Hyperinsulinism", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Insulinoma", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Minimally Invasive Surgical Procedures", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Pancreatic Neoplasms", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Patient Selection", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Prognosis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Reoperation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Retrospective Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Treatment Outcome", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Section Endocrine Surgery, Division of General Surgery, Department of Surgery, Medical University of Vienna, Vienna, Austria", 
          "id": "http://www.grid.ac/institutes/grid.22937.3d", 
          "name": [
            "Section Endocrine Surgery, Division of General Surgery, Department of Surgery, Medical University of Vienna, Vienna, Austria"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kaczirek", 
        "givenName": "Klaus", 
        "id": "sg:person.01163404744.70", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01163404744.70"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Section Endocrine Surgery, Division of General Surgery, Department of Surgery, Medical University of Vienna, Vienna, Austria", 
          "id": "http://www.grid.ac/institutes/grid.22937.3d", 
          "name": [
            "Section Endocrine Surgery, Division of General Surgery, Department of Surgery, Medical University of Vienna, Vienna, Austria"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Asari", 
        "givenName": "Reza", 
        "id": "sg:person.01275773331.80", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01275773331.80"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Section Endocrine Surgery, Division of General Surgery, Department of Surgery, Medical University of Vienna, Vienna, Austria", 
          "id": "http://www.grid.ac/institutes/grid.22937.3d", 
          "name": [
            "Section Endocrine Surgery, Division of General Surgery, Department of Surgery, Medical University of Vienna, Vienna, Austria"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Scheuba", 
        "givenName": "Christian", 
        "id": "sg:person.0617351314.15", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0617351314.15"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Section Endocrine Surgery, Division of General Surgery, Department of Surgery, Medical University of Vienna, Vienna, Austria", 
          "id": "http://www.grid.ac/institutes/grid.22937.3d", 
          "name": [
            "Section Endocrine Surgery, Division of General Surgery, Department of Surgery, Medical University of Vienna, Vienna, Austria"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Niederle", 
        "givenName": "Bruno", 
        "id": "sg:person.0671724636.94", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0671724636.94"
        ], 
        "type": "Person"
      }
    ], 
    "datePublished": "2005-01-01", 
    "datePublishedReg": "2005-01-01", 
    "description": "BACKGROUND: Experience with minimally invasive surgery for organic hyperinsulinism is limited. No criteria for patient selection with special regard to sporadic, hereditary, multiple and malignant tumors have been defined. METHODS: The estimated success rate of endoscopic surgery was retrospectively calculated by analysing 34 consecutive patients with organic hyperinsulinism operated on by open surgery. A literature search was undertaken to better define indications for endoscopic procedures. Differences in postoperative outcome (morbidity) between endoscopic and open procedures were analysed. RESULTS: Twenty-eight of 31 patients (90%) with solitary insulinomas and one of three patients with multiple insulinomas were correctly localized preoperatively. Twenty-six enucleations (76%) and eight distal resections (24%) including one endoscopic tail resection were performed. Theoretically only 14 out of 34 patients (41%) would have been suitable for endoscopic surgery (8 enucleations and 6 patients for distal resections which were enucleated using an open approach). Pancreatic fistulas were documented in three patients (9%). Reviewing 34 publications, 49 enucleations, 36 distal resections and 15 conversions to open surgery were performed, showing a higher proportion of distal resections in endoscopic surgery. The spleen was preserved in 88% of cases. Fourteen fistulas occurred after enucleations. CONCLUSIONS: Only solitary insulinomas localized in the pancreatic tail or superficially in the body or head may be candidates for endoscopic procedures. Patients with multiple insulinomas, MEN-1 syndrome or malignancy should undergo open surgery.", 
    "genre": "article", 
    "id": "sg:pub.10.1007/s00508-004-0287-6", 
    "inLanguage": "en", 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1070586", 
        "issn": [
          "1026-4906", 
          "1563-2571"
        ], 
        "name": "Wiener klinische Wochenschrift", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1-2", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "117"
      }
    ], 
    "keywords": [
      "organic hyperinsulinism", 
      "distal resection", 
      "endoscopic surgery", 
      "solitary insulinomas", 
      "multiple insulinomas", 
      "open surgery", 
      "endoscopic procedures", 
      "MEN-1 syndrome", 
      "postoperative outcomes", 
      "pancreatic fistula", 
      "consecutive patients", 
      "pancreatic tail", 
      "patient selection", 
      "tail resection", 
      "open procedure", 
      "malignant tumors", 
      "surgery", 
      "patients", 
      "resection", 
      "insulinoma", 
      "hyperinsulinism", 
      "literature search", 
      "invasive surgery", 
      "enucleation", 
      "success rate", 
      "fistula", 
      "higher proportion", 
      "special regard", 
      "malignancy", 
      "syndrome", 
      "tumors", 
      "spleen", 
      "outcomes", 
      "procedure", 
      "indications", 
      "head", 
      "proportion", 
      "differences", 
      "criteria", 
      "cases", 
      "rate", 
      "experience", 
      "regard", 
      "body", 
      "candidates", 
      "search", 
      "publications", 
      "selection", 
      "tail", 
      "conversion", 
      "endoscopic tail resection"
    ], 
    "name": "Organic hyperinsulinism and endoscopic surgery", 
    "pagination": "19-25", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1040733162"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s00508-004-0287-6"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "15986586"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s00508-004-0287-6", 
      "https://app.dimensions.ai/details/publication/pub.1040733162"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2021-11-01T18:08", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20211101/entities/gbq_results/article/article_410.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1007/s00508-004-0287-6"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00508-004-0287-6'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00508-004-0287-6'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00508-004-0287-6'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00508-004-0287-6'


 

This table displays all metadata directly associated to this object as RDF triples.

178 TRIPLES      21 PREDICATES      88 URIs      80 LITERALS      18 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s00508-004-0287-6 schema:about N0ff6e12135694fd78e43a0e900285a96
2 N34c6b954cd124d2894e83b7e01ea9001
3 N3b5679b05ff6428b935317b985cf3c1f
4 N44e3519213fd4280934cb853eed4b2a2
5 N4b4cf3e1d4ff4eeea3bc1d9892ad9f8c
6 N8cb0d218f0774805b9ea20f61c82d0f8
7 Na33931c1251642e1a3426694d27ab45d
8 Na57d4f24bdf44d7c918ecbbefe3c7b28
9 Na6b0c735b3744d159047a84fe474f0af
10 Nc4a43710912d4c649b9cd4de45505160
11 Nf9d3140a36964a9cabd8f1a3624294e8
12 anzsrc-for:11
13 anzsrc-for:1103
14 schema:author Nd4050624168c4e708994bf6243d1ed74
15 schema:datePublished 2005-01-01
16 schema:datePublishedReg 2005-01-01
17 schema:description BACKGROUND: Experience with minimally invasive surgery for organic hyperinsulinism is limited. No criteria for patient selection with special regard to sporadic, hereditary, multiple and malignant tumors have been defined. METHODS: The estimated success rate of endoscopic surgery was retrospectively calculated by analysing 34 consecutive patients with organic hyperinsulinism operated on by open surgery. A literature search was undertaken to better define indications for endoscopic procedures. Differences in postoperative outcome (morbidity) between endoscopic and open procedures were analysed. RESULTS: Twenty-eight of 31 patients (90%) with solitary insulinomas and one of three patients with multiple insulinomas were correctly localized preoperatively. Twenty-six enucleations (76%) and eight distal resections (24%) including one endoscopic tail resection were performed. Theoretically only 14 out of 34 patients (41%) would have been suitable for endoscopic surgery (8 enucleations and 6 patients for distal resections which were enucleated using an open approach). Pancreatic fistulas were documented in three patients (9%). Reviewing 34 publications, 49 enucleations, 36 distal resections and 15 conversions to open surgery were performed, showing a higher proportion of distal resections in endoscopic surgery. The spleen was preserved in 88% of cases. Fourteen fistulas occurred after enucleations. CONCLUSIONS: Only solitary insulinomas localized in the pancreatic tail or superficially in the body or head may be candidates for endoscopic procedures. Patients with multiple insulinomas, MEN-1 syndrome or malignancy should undergo open surgery.
18 schema:genre article
19 schema:inLanguage en
20 schema:isAccessibleForFree false
21 schema:isPartOf N0319eb87c91a4a9cbd138ea3944836ba
22 N03fd0104cdd74864ba91acc33d154f11
23 sg:journal.1070586
24 schema:keywords MEN-1 syndrome
25 body
26 candidates
27 cases
28 consecutive patients
29 conversion
30 criteria
31 differences
32 distal resection
33 endoscopic procedures
34 endoscopic surgery
35 endoscopic tail resection
36 enucleation
37 experience
38 fistula
39 head
40 higher proportion
41 hyperinsulinism
42 indications
43 insulinoma
44 invasive surgery
45 literature search
46 malignancy
47 malignant tumors
48 multiple insulinomas
49 open procedure
50 open surgery
51 organic hyperinsulinism
52 outcomes
53 pancreatic fistula
54 pancreatic tail
55 patient selection
56 patients
57 postoperative outcomes
58 procedure
59 proportion
60 publications
61 rate
62 regard
63 resection
64 search
65 selection
66 solitary insulinomas
67 special regard
68 spleen
69 success rate
70 surgery
71 syndrome
72 tail
73 tail resection
74 tumors
75 schema:name Organic hyperinsulinism and endoscopic surgery
76 schema:pagination 19-25
77 schema:productId N18cfd477c28a45d99b6c7e60f02810e6
78 N19ad261d44644b75bfe7866565f19c05
79 Nc2118dbd4d634557a1c643099fa3594c
80 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040733162
81 https://doi.org/10.1007/s00508-004-0287-6
82 schema:sdDatePublished 2021-11-01T18:08
83 schema:sdLicense https://scigraph.springernature.com/explorer/license/
84 schema:sdPublisher N239183be23ba4e638c189800efe00f05
85 schema:url https://doi.org/10.1007/s00508-004-0287-6
86 sgo:license sg:explorer/license/
87 sgo:sdDataset articles
88 rdf:type schema:ScholarlyArticle
89 N0319eb87c91a4a9cbd138ea3944836ba schema:issueNumber 1-2
90 rdf:type schema:PublicationIssue
91 N03fd0104cdd74864ba91acc33d154f11 schema:volumeNumber 117
92 rdf:type schema:PublicationVolume
93 N0ff6e12135694fd78e43a0e900285a96 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
94 schema:name Reoperation
95 rdf:type schema:DefinedTerm
96 N110e2177e8df4506b5e1d823fd5e6902 rdf:first sg:person.0671724636.94
97 rdf:rest rdf:nil
98 N18cfd477c28a45d99b6c7e60f02810e6 schema:name pubmed_id
99 schema:value 15986586
100 rdf:type schema:PropertyValue
101 N19972d145ae94328b3621aa0437a0529 rdf:first sg:person.0617351314.15
102 rdf:rest N110e2177e8df4506b5e1d823fd5e6902
103 N19ad261d44644b75bfe7866565f19c05 schema:name dimensions_id
104 schema:value pub.1040733162
105 rdf:type schema:PropertyValue
106 N239183be23ba4e638c189800efe00f05 schema:name Springer Nature - SN SciGraph project
107 rdf:type schema:Organization
108 N34c6b954cd124d2894e83b7e01ea9001 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
109 schema:name Insulinoma
110 rdf:type schema:DefinedTerm
111 N3b5679b05ff6428b935317b985cf3c1f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
112 schema:name Retrospective Studies
113 rdf:type schema:DefinedTerm
114 N44e3519213fd4280934cb853eed4b2a2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
115 schema:name Pancreatic Neoplasms
116 rdf:type schema:DefinedTerm
117 N4b4cf3e1d4ff4eeea3bc1d9892ad9f8c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
118 schema:name Hyperinsulinism
119 rdf:type schema:DefinedTerm
120 N6a9790b272584eba83aad3073452ba4e rdf:first sg:person.01275773331.80
121 rdf:rest N19972d145ae94328b3621aa0437a0529
122 N8cb0d218f0774805b9ea20f61c82d0f8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
123 schema:name Treatment Outcome
124 rdf:type schema:DefinedTerm
125 Na33931c1251642e1a3426694d27ab45d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
126 schema:name Prognosis
127 rdf:type schema:DefinedTerm
128 Na57d4f24bdf44d7c918ecbbefe3c7b28 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
129 schema:name Endoscopy, Digestive System
130 rdf:type schema:DefinedTerm
131 Na6b0c735b3744d159047a84fe474f0af schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
132 schema:name Humans
133 rdf:type schema:DefinedTerm
134 Nc2118dbd4d634557a1c643099fa3594c schema:name doi
135 schema:value 10.1007/s00508-004-0287-6
136 rdf:type schema:PropertyValue
137 Nc4a43710912d4c649b9cd4de45505160 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
138 schema:name Patient Selection
139 rdf:type schema:DefinedTerm
140 Nd4050624168c4e708994bf6243d1ed74 rdf:first sg:person.01163404744.70
141 rdf:rest N6a9790b272584eba83aad3073452ba4e
142 Nf9d3140a36964a9cabd8f1a3624294e8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
143 schema:name Minimally Invasive Surgical Procedures
144 rdf:type schema:DefinedTerm
145 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
146 schema:name Medical and Health Sciences
147 rdf:type schema:DefinedTerm
148 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
149 schema:name Clinical Sciences
150 rdf:type schema:DefinedTerm
151 sg:journal.1070586 schema:issn 1026-4906
152 1563-2571
153 schema:name Wiener klinische Wochenschrift
154 schema:publisher Springer Nature
155 rdf:type schema:Periodical
156 sg:person.01163404744.70 schema:affiliation grid-institutes:grid.22937.3d
157 schema:familyName Kaczirek
158 schema:givenName Klaus
159 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01163404744.70
160 rdf:type schema:Person
161 sg:person.01275773331.80 schema:affiliation grid-institutes:grid.22937.3d
162 schema:familyName Asari
163 schema:givenName Reza
164 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01275773331.80
165 rdf:type schema:Person
166 sg:person.0617351314.15 schema:affiliation grid-institutes:grid.22937.3d
167 schema:familyName Scheuba
168 schema:givenName Christian
169 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0617351314.15
170 rdf:type schema:Person
171 sg:person.0671724636.94 schema:affiliation grid-institutes:grid.22937.3d
172 schema:familyName Niederle
173 schema:givenName Bruno
174 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0671724636.94
175 rdf:type schema:Person
176 grid-institutes:grid.22937.3d schema:alternateName Section Endocrine Surgery, Division of General Surgery, Department of Surgery, Medical University of Vienna, Vienna, Austria
177 schema:name Section Endocrine Surgery, Division of General Surgery, Department of Surgery, Medical University of Vienna, Vienna, Austria
178 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...