Prune-belly syndrome diagnosed at 14 weeks’ gestation with severe urethral obstruction but normal kidneys View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1999-03

AUTHORS

Midori Shigeta, M. Nagata, Hiroaki Shimoyamada, Sawako Shibata, Suzuka Okuno, Hiromi Hamada, Teruo Watanabe

ABSTRACT

A fetus was diagnosed with prune-belly syndrome (PBS) found by ultrasound demonstration of cystomegaly at 12 weeks’ gestation. Fetal urinary electrolyte and β2-microglobulin concentrations at 14 weeks’ gestation indicated a poor renal prognosis. The pregnancy was therefore terminated. An autopsy showed defects of the abdominal wall muscles and megalocystis caused by severe urethral obstruction. However, the kidneys were histologically normal. Together with previous reports, the present case suggests that renal dysplasia in PBS with severe uretheral obstruction may develop after 14 weeks’ gestation. We discuss the possibility of preventing the development of renal dysplasia in PBS by early prenatal decompression of the obstructed fetal urinary tract. More... »

PAGES

135-137

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s004670050580

DOI

http://dx.doi.org/10.1007/s004670050580

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1041604558

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/10229001


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