Regulatory molecules in kidney development View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2000-02

AUTHORS

C.R. Burrow

ABSTRACT

The molecular regulation of the complex inductive events associated with formation of the vertebrate excretory system has been progressively elucidated as a result of both genetic and tissue culture approaches. Kidney organogenesis is initiated and maintained by a series of reciprocal inductive interactions between different tissues derived from the intermediolateral mesoderm to form the nephrons and collecting system of the metanephric kidney. Recent progress in this area has resulted in the identification of regulatory systems controlling branching morphogenesis of the ureteric bud, formation of the early renal vesicle and the glomerulus. These events are controlled by genes that regulate pattern formation, cellular proliferation, and differentiation in other tissues. Although it is not yet possible to completely identify a complete genetic pathway required for any one of the many steps in nephrogenesis, it is now evident that pathways previously identified in studies of mesenchymal-epithelial inductive mechanisms in limb bud, neural tissues, lung, and gut have direct relevance to the study of these processes in kidney development. For instance, a primary system for pattern formation involving retinoic acid, homeobox genes, sonic hedgehog, fibroblast growth factor (FGF), and an FGF receptor all appear to function in limb, lung, and kidney organogenesis. A major challenge is determining how this common cast of signalling molecules plays a specific role in kidney development essential to nephrogenesis, which results in the unique structural organization of the adult kidney. From this more-sophisticated understanding will come important insights relevant to understanding the molecular basis of developmental malformations of the kidney necessary for the prevention and treatment of these disorders. More... »

PAGES

240-253

References to SciGraph publications

  • 1996-07. Renal agenesis and the absence of enteric neurons in mice lacking GDNF in NATURE
  • 1997-05. Altered cell differentiation and proliferation in mice lacking p57KIP2 indicates a role in Beckwith–Wiedemann syndrome in NATURE
  • 1997-06. Neurturin responsiveness requires a GPI-linked receptor and the Ret receptor tyrosine kinase in NATURE
  • 1997-06. A GPI-linked protein that interacts with Ret to form a candidate neurturin receptor in NATURE
  • 1996-07. Defects in enteric innervation and kidney development in mice lacking GDNF in NATURE
  • 1996-12. Neurturin, a relative of glial-cell-line-derived neurotrophic factor in NATURE
  • 1998-01. Induction of epithelial tubules by growth factor HGF depends on the STAT pathway in NATURE
  • 1994-12. Epithelial transformation of metanephric mesenchyme in the developing kidney regulated by Wnt-4 in NATURE
  • 1996-05. Metanephros organogenesis is highly stimulated by vitamin A derivatives in organ culture in KIDNEY INTERNATIONAL
  • 1998-05. Limb and kidney defects in Lmx1b mutant mice suggest an involvement of LMX1B in human nail patella syndrome in NATURE GENETICS
  • 1994-01. Defects in the kidney and enteric nervous system of mice lacking the tyrosine kinase receptor Ret in NATURE
  • 1997-12. Donor splice-site mutations in WT1 are responsible for Frasier syndrome in NATURE GENETICS
  • 1997-10. Perinatal lethality with kidney and pancreas defects in mice with a targetted Pkd1 mutation in NATURE GENETICS
  • 1998-01. Loss of WT1 function leads to ectopic myogenesis in Wilms' tumour in NATURE GENETICS
  • 1996-03. Mutations in GPC3, a glypican gene, cause the Simpson-Golabi-Behmel overgrowth syndrome in NATURE GENETICS
  • 1998-09. A lungful of transcription factors in NATURE GENETICS
  • 1995-02. Apert syndrome results from localized mutations of FGFR2 and is allelic with Crouzon syndrome in NATURE GENETICS
  • 1998-11. Mild vitamin A deficiency leads to inborn nephron deficit in the rat in KIDNEY INTERNATIONAL
  • 1998-01. Mutations in the SALL1 putative transcription factor gene cause Townes-Brocks syndrome in NATURE GENETICS
  • 1995-03. Requirement for LIml in head-organizer function in NATURE
  • 1997-05. Molecular bases of human kidney malformations in PEDIATRIC NEPHROLOGY
  • 1995-06. Absence of radius and ulna in mice lacking hoxa-11 andhoxd-11 in NATURE
  • 1997-10. A novel gene encoding an SH3 domain protein is mutated in nephronophthisis type 1 in NATURE GENETICS
  • 1995-02. Scatter factor/hepatocyte growth factor is essential for liver development in NATURE
  • 1998-05. Mutations in LMX1B cause abnormal skeletal patterning and renal dysplasia in nail patella syndrome in NATURE GENETICS
  • 1998-09. Origins and formation of microvasculature in the developing kidney in KIDNEY INTERNATIONAL
  • 1998-09. Role of angiotensin in renal vascular development in KIDNEY INTERNATIONAL
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s004670050049

    DOI

    http://dx.doi.org/10.1007/s004670050049

    DIMENSIONS

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    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/10752765


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