The importance of ambulatory blood pressure monitoring for diagnosing masked hypertension in patients with renal parenchymal scarring View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2022-09-26

AUTHORS

Deniz Karakaya, Evrim Kargın Çakıcı, Fatma Yazılıtaş, Tülin Güngör, Evra Çelikkaya, Esra Bağlan, Mehmet Bülbül

ABSTRACT

Background The most well-known and common long-term complication in children with renal parenchymal scarring (RPS) is hypertension (HT). The present study aimed to evaluate the presence of HT in children with RPS based on ambulatory blood pressure monitoring (ABPM) and to compare the patients’ blood pressure (BP) to that in healthy controls matched for age, gender, and BMI.MethodsThe study included 55 patients aged < 18 years diagnosed with RPS who were followed up for ≥ 1 year and 48 healthy controls matched for age, gender, and BMI.ResultsMean age in the RPS group was 12.8 ± 3.3 years, and 49.1% of the group were female. Among the RPS patients, 28 were diagnosed with HT based on ABPM, of which 18 (32.7%) had an office BP < 90th percentile for age, gender, and height; seven had an office BP between the 90–95th percentiles for age, gender, and height; and three had an office BP > 95 percentile for age, gender, and height. The difference in detection of HT based on ABPM between the two groups was significant (P = 0.00).ConclusionsEarly diagnosis of HT via ABPM can help prevent development of kidney failure and cardiovascular disease in patients with RPS, significantly reducing the rates of morbidity and mortality. All children with RPS should be evaluated via ABPM, even if office BP measurements are normal.Graphical abstract"A higher resolution version of the Graphical abstract is available as Supplementary information" More... »

PAGES

1-8

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00467-022-05754-4

DOI

http://dx.doi.org/10.1007/s00467-022-05754-4

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1151328754

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/36156734


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