Risk factors for post-nephrectomy hypotension in pediatric patients View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2021-05-14

AUTHORS

Kentaro Nishi, Koichi Kamei, Masao Ogura, Mai Sato, Sho Ishiwa, Yoko Shioda, Chikako Kiyotani, Kimikazu Matsumoto, Kandai Nozu, Kenji Ishikura, Shuichi Ito

ABSTRACT

BackgroundAlthough hypotension is a life-threatening complication of nephrectomy in children, risk factors for its development remain unknown. We evaluated the incidence, clinical course, and associated risk factors of pediatric post-nephrectomy hypotension in an observational study.MethodsThis retrospective observational study included the clinical data of children who underwent nephrectomy in our center between 2002 and 2020. Patients undergoing nephrectomy at kidney transplantation and those who developed hypotension before nephrectomy were excluded.ResultsThe study included 55 nephrectomies in 51 patients, including 42 unilateral, 4 two-stage bilateral, and 5 simultaneous bilateral nephrectomies. The diagnoses were isolated Wilms tumor, neuroblastoma, congenital nephrotic syndrome, Denys-Drash syndrome, WAGR (Wilms tumor, aniridia, genitourinary malformations, and mental retardation) syndrome, and autosomal recessive polycystic kidney disease in 24, 10, 9, 6, 1, and 1 patient, respectively. Post-nephrectomy hypotension developed in 11 (20%) patients. Two patients (3.6%) had persistent hypotension; both had their kidneys resected, and one patient (1.8%) died. Male sex, kidney disease, resection of both kidneys, low estimated glomerular filtration rate, increased left ventricular posterior wall thickness in diastole, hypertension before nephrectomy, antihypertensive use, hyperreninemia, and hyperaldosteronism were significantly associated with post-nephrectomy hypotension. Multivariate logistic regression analysis revealed that hypertension before nephrectomy was the only significant risk factor for post-nephrectomy hypotension (P = 0.04).ConclusionsHypertension before nephrectomy is a significant risk factor for pediatric post-nephrectomy hypotension. Life-threatening hypotension, which might occur after bilateral nephrectomy in infants, should be considered, especially in children with higher risks. More... »

PAGES

3699-3709

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00467-021-05115-7

DOI

http://dx.doi.org/10.1007/s00467-021-05115-7

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1138067817

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/33988732


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Child", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Hypotension", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Nephrectomy", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Retrospective Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Risk Factors", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Division of Nephrology and Rheumatology, National Center for Child Health and Development, 2-10-1, Okura, Setagaya-ku, 157-8535, Tokyo, Japan", 
          "id": "http://www.grid.ac/institutes/grid.63906.3a", 
          "name": [
            "Division of Nephrology and Rheumatology, National Center for Child Health and Development, 2-10-1, Okura, Setagaya-ku, 157-8535, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Nishi", 
        "givenName": "Kentaro", 
        "id": "sg:person.010612274451.16", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010612274451.16"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Division of Nephrology and Rheumatology, National Center for Child Health and Development, 2-10-1, Okura, Setagaya-ku, 157-8535, Tokyo, Japan", 
          "id": "http://www.grid.ac/institutes/grid.63906.3a", 
          "name": [
            "Division of Nephrology and Rheumatology, National Center for Child Health and Development, 2-10-1, Okura, Setagaya-ku, 157-8535, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kamei", 
        "givenName": "Koichi", 
        "id": "sg:person.01316365041.17", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01316365041.17"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Division of Nephrology and Rheumatology, National Center for Child Health and Development, 2-10-1, Okura, Setagaya-ku, 157-8535, Tokyo, Japan", 
          "id": "http://www.grid.ac/institutes/grid.63906.3a", 
          "name": [
            "Division of Nephrology and Rheumatology, National Center for Child Health and Development, 2-10-1, Okura, Setagaya-ku, 157-8535, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ogura", 
        "givenName": "Masao", 
        "id": "sg:person.01174574062.16", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01174574062.16"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Division of Nephrology and Rheumatology, National Center for Child Health and Development, 2-10-1, Okura, Setagaya-ku, 157-8535, Tokyo, Japan", 
          "id": "http://www.grid.ac/institutes/grid.63906.3a", 
          "name": [
            "Division of Nephrology and Rheumatology, National Center for Child Health and Development, 2-10-1, Okura, Setagaya-ku, 157-8535, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sato", 
        "givenName": "Mai", 
        "id": "sg:person.01060345462.48", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01060345462.48"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Pediatric Nephrology, Tokyo Women\u2019s Medical University, Tokyo, Japan", 
          "id": "http://www.grid.ac/institutes/grid.410818.4", 
          "name": [
            "Division of Nephrology and Rheumatology, National Center for Child Health and Development, 2-10-1, Okura, Setagaya-ku, 157-8535, Tokyo, Japan", 
            "Department of Pediatric Nephrology, Tokyo Women\u2019s Medical University, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ishiwa", 
        "givenName": "Sho", 
        "id": "sg:person.015722404651.24", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015722404651.24"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Children\u2019s Cancer Center, National Center for Child Health and Development, Tokyo, Japan", 
          "id": "http://www.grid.ac/institutes/grid.63906.3a", 
          "name": [
            "Children\u2019s Cancer Center, National Center for Child Health and Development, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Shioda", 
        "givenName": "Yoko", 
        "id": "sg:person.01305716526.82", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01305716526.82"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Children\u2019s Cancer Center, National Center for Child Health and Development, Tokyo, Japan", 
          "id": "http://www.grid.ac/institutes/grid.63906.3a", 
          "name": [
            "Children\u2019s Cancer Center, National Center for Child Health and Development, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kiyotani", 
        "givenName": "Chikako", 
        "id": "sg:person.01227352602.17", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01227352602.17"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Children\u2019s Cancer Center, National Center for Child Health and Development, Tokyo, Japan", 
          "id": "http://www.grid.ac/institutes/grid.63906.3a", 
          "name": [
            "Children\u2019s Cancer Center, National Center for Child Health and Development, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Matsumoto", 
        "givenName": "Kimikazu", 
        "id": "sg:person.01214356060.39", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01214356060.39"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Pediatrics, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan", 
          "id": "http://www.grid.ac/institutes/grid.31432.37", 
          "name": [
            "Department of Pediatrics, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Nozu", 
        "givenName": "Kandai", 
        "id": "sg:person.0717317506.56", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0717317506.56"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Pediatrics, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan", 
          "id": "http://www.grid.ac/institutes/grid.410786.c", 
          "name": [
            "Division of Nephrology and Rheumatology, National Center for Child Health and Development, 2-10-1, Okura, Setagaya-ku, 157-8535, Tokyo, Japan", 
            "Department of Pediatrics, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ishikura", 
        "givenName": "Kenji", 
        "id": "sg:person.01112735663.13", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01112735663.13"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Pediatrics, Yokohama City University Graduate School of Medicine, Yokohama, Kanagawa, Japan", 
          "id": "http://www.grid.ac/institutes/grid.268441.d", 
          "name": [
            "Division of Nephrology and Rheumatology, National Center for Child Health and Development, 2-10-1, Okura, Setagaya-ku, 157-8535, Tokyo, Japan", 
            "Department of Pediatrics, Yokohama City University Graduate School of Medicine, Yokohama, Kanagawa, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ito", 
        "givenName": "Shuichi", 
        "id": "sg:person.012302533312.63", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012302533312.63"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/bf00445660", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044024908", 
          "https://doi.org/10.1007/bf00445660"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/s41598-020-71956-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1131251858", 
          "https://doi.org/10.1038/s41598-020-71956-1"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s004670100599", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027652486", 
          "https://doi.org/10.1007/s004670100599"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00467-010-1656-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008902248", 
          "https://doi.org/10.1007/s00467-010-1656-1"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00467-020-04578-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1127413042", 
          "https://doi.org/10.1007/s00467-020-04578-4"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00467-003-1131-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1075267267", 
          "https://doi.org/10.1007/s00467-003-1131-3"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00467-012-2311-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046710337", 
          "https://doi.org/10.1007/s00467-012-2311-9"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10157-019-01732-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1113301048", 
          "https://doi.org/10.1007/s10157-019-01732-7"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00858984", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008028111", 
          "https://doi.org/10.1007/bf00858984"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2021-05-14", 
    "datePublishedReg": "2021-05-14", 
    "description": "BackgroundAlthough hypotension is a life-threatening complication of nephrectomy in children, risk factors for its development remain unknown. We evaluated the incidence, clinical course, and associated risk factors of pediatric post-nephrectomy hypotension in an observational study.MethodsThis retrospective observational study included the clinical data of children who underwent nephrectomy in our center between 2002 and 2020. Patients undergoing nephrectomy at kidney transplantation and those who developed hypotension before nephrectomy were excluded.ResultsThe study included 55 nephrectomies in 51 patients, including 42 unilateral, 4 two-stage bilateral, and 5 simultaneous bilateral nephrectomies. The diagnoses were isolated Wilms tumor, neuroblastoma, congenital nephrotic syndrome, Denys-Drash syndrome, WAGR (Wilms tumor, aniridia, genitourinary malformations, and mental retardation) syndrome, and autosomal recessive polycystic kidney disease in 24, 10, 9, 6, 1, and 1 patient, respectively. Post-nephrectomy hypotension developed in 11 (20%) patients. Two patients (3.6%) had persistent hypotension; both had their kidneys resected, and one patient (1.8%) died. Male sex, kidney disease, resection of both kidneys, low estimated glomerular filtration rate, increased left ventricular posterior wall thickness in diastole, hypertension before nephrectomy, antihypertensive use, hyperreninemia, and hyperaldosteronism were significantly associated with post-nephrectomy hypotension. Multivariate logistic regression analysis revealed that hypertension before nephrectomy was the only significant risk factor for post-nephrectomy hypotension (P = 0.04).ConclusionsHypertension before nephrectomy is a significant risk factor for pediatric post-nephrectomy hypotension. Life-threatening hypotension, which might occur after bilateral nephrectomy in infants, should be considered, especially in children with higher risks.", 
    "genre": "article", 
    "id": "sg:pub.10.1007/s00467-021-05115-7", 
    "inLanguage": "en", 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1097267", 
        "issn": [
          "0931-041X", 
          "1432-198X"
        ], 
        "name": "Pediatric Nephrology", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "11", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "36"
      }
    ], 
    "keywords": [
      "significant risk factors", 
      "risk factors", 
      "bilateral nephrectomy", 
      "kidney disease", 
      "observational study", 
      "low estimated glomerular filtration rate", 
      "left ventricular posterior wall thickness", 
      "MethodsThis retrospective observational study", 
      "estimated glomerular filtration rate", 
      "only significant risk factor", 
      "ventricular posterior wall thickness", 
      "multivariate logistic regression analysis", 
      "simultaneous bilateral nephrectomy", 
      "life-threatening hypotension", 
      "life-threatening complications", 
      "retrospective observational study", 
      "autosomal recessive polycystic kidney disease", 
      "glomerular filtration rate", 
      "posterior wall thickness", 
      "recessive polycystic kidney disease", 
      "logistic regression analysis", 
      "congenital nephrotic syndrome", 
      "polycystic kidney disease", 
      "persistent hypotension", 
      "antihypertensive use", 
      "kidney transplantation", 
      "clinical course", 
      "pediatric patients", 
      "nephrotic syndrome", 
      "male sex", 
      "filtration rate", 
      "hypotension", 
      "clinical data", 
      "ResultsThe study", 
      "nephrectomy", 
      "high risk", 
      "patients", 
      "Denys-Drash syndrome", 
      "syndrome", 
      "Wilms tumor", 
      "hypertension", 
      "regression analysis", 
      "kidney", 
      "disease", 
      "children", 
      "WAGR syndrome", 
      "wall thickness", 
      "ConclusionsHypertension", 
      "hyperreninemia", 
      "hyperaldosteronism", 
      "resection", 
      "complications", 
      "factors", 
      "transplantation", 
      "neuroblastoma", 
      "infants", 
      "tumors", 
      "incidence", 
      "diagnosis", 
      "diastole", 
      "study", 
      "Bilateral", 
      "sex", 
      "risk", 
      "course", 
      "center", 
      "rate", 
      "use", 
      "data", 
      "development", 
      "analysis", 
      "thickness"
    ], 
    "name": "Risk factors for post-nephrectomy hypotension in pediatric patients", 
    "pagination": "3699-3709", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1138067817"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s00467-021-05115-7"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "33988732"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s00467-021-05115-7", 
      "https://app.dimensions.ai/details/publication/pub.1138067817"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-05-10T10:30", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20220509/entities/gbq_results/article/article_890.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1007/s00467-021-05115-7"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00467-021-05115-7'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00467-021-05115-7'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00467-021-05115-7'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00467-021-05115-7'


 

This table displays all metadata directly associated to this object as RDF triples.

289 TRIPLES      22 PREDICATES      115 URIs      98 LITERALS      15 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s00467-021-05115-7 schema:about N43084d1f63834dcc968994f32d7a781e
2 N47e3583b2f4c4e9ebc873d4062260cc4
3 N4faa36fca97146798ac1124d1e70be76
4 N5c5ea04b942d400f9d45b9c6fc98fc52
5 N966d97b9d61e4031ac4f4df542597b85
6 Nabd1f919da134689bd681a1b68488362
7 Nc3233b2d49ec4fe68cd168178d9cd9db
8 Nc6aa0c3b199a4a1dbec2e77a4131078c
9 anzsrc-for:11
10 anzsrc-for:1103
11 schema:author N09c9672f3bd641a3be7d31525039b1cc
12 schema:citation sg:pub.10.1007/bf00445660
13 sg:pub.10.1007/bf00858984
14 sg:pub.10.1007/s00467-003-1131-3
15 sg:pub.10.1007/s00467-010-1656-1
16 sg:pub.10.1007/s00467-012-2311-9
17 sg:pub.10.1007/s00467-020-04578-4
18 sg:pub.10.1007/s004670100599
19 sg:pub.10.1007/s10157-019-01732-7
20 sg:pub.10.1038/s41598-020-71956-1
21 schema:datePublished 2021-05-14
22 schema:datePublishedReg 2021-05-14
23 schema:description BackgroundAlthough hypotension is a life-threatening complication of nephrectomy in children, risk factors for its development remain unknown. We evaluated the incidence, clinical course, and associated risk factors of pediatric post-nephrectomy hypotension in an observational study.MethodsThis retrospective observational study included the clinical data of children who underwent nephrectomy in our center between 2002 and 2020. Patients undergoing nephrectomy at kidney transplantation and those who developed hypotension before nephrectomy were excluded.ResultsThe study included 55 nephrectomies in 51 patients, including 42 unilateral, 4 two-stage bilateral, and 5 simultaneous bilateral nephrectomies. The diagnoses were isolated Wilms tumor, neuroblastoma, congenital nephrotic syndrome, Denys-Drash syndrome, WAGR (Wilms tumor, aniridia, genitourinary malformations, and mental retardation) syndrome, and autosomal recessive polycystic kidney disease in 24, 10, 9, 6, 1, and 1 patient, respectively. Post-nephrectomy hypotension developed in 11 (20%) patients. Two patients (3.6%) had persistent hypotension; both had their kidneys resected, and one patient (1.8%) died. Male sex, kidney disease, resection of both kidneys, low estimated glomerular filtration rate, increased left ventricular posterior wall thickness in diastole, hypertension before nephrectomy, antihypertensive use, hyperreninemia, and hyperaldosteronism were significantly associated with post-nephrectomy hypotension. Multivariate logistic regression analysis revealed that hypertension before nephrectomy was the only significant risk factor for post-nephrectomy hypotension (P = 0.04).ConclusionsHypertension before nephrectomy is a significant risk factor for pediatric post-nephrectomy hypotension. Life-threatening hypotension, which might occur after bilateral nephrectomy in infants, should be considered, especially in children with higher risks.
24 schema:genre article
25 schema:inLanguage en
26 schema:isAccessibleForFree false
27 schema:isPartOf Ndf3dfc7c29454646903ef154493c6322
28 Nfded7e04380e415892d32cd6243edbc8
29 sg:journal.1097267
30 schema:keywords Bilateral
31 ConclusionsHypertension
32 Denys-Drash syndrome
33 MethodsThis retrospective observational study
34 ResultsThe study
35 WAGR syndrome
36 Wilms tumor
37 analysis
38 antihypertensive use
39 autosomal recessive polycystic kidney disease
40 bilateral nephrectomy
41 center
42 children
43 clinical course
44 clinical data
45 complications
46 congenital nephrotic syndrome
47 course
48 data
49 development
50 diagnosis
51 diastole
52 disease
53 estimated glomerular filtration rate
54 factors
55 filtration rate
56 glomerular filtration rate
57 high risk
58 hyperaldosteronism
59 hyperreninemia
60 hypertension
61 hypotension
62 incidence
63 infants
64 kidney
65 kidney disease
66 kidney transplantation
67 left ventricular posterior wall thickness
68 life-threatening complications
69 life-threatening hypotension
70 logistic regression analysis
71 low estimated glomerular filtration rate
72 male sex
73 multivariate logistic regression analysis
74 nephrectomy
75 nephrotic syndrome
76 neuroblastoma
77 observational study
78 only significant risk factor
79 patients
80 pediatric patients
81 persistent hypotension
82 polycystic kidney disease
83 posterior wall thickness
84 rate
85 recessive polycystic kidney disease
86 regression analysis
87 resection
88 retrospective observational study
89 risk
90 risk factors
91 sex
92 significant risk factors
93 simultaneous bilateral nephrectomy
94 study
95 syndrome
96 thickness
97 transplantation
98 tumors
99 use
100 ventricular posterior wall thickness
101 wall thickness
102 schema:name Risk factors for post-nephrectomy hypotension in pediatric patients
103 schema:pagination 3699-3709
104 schema:productId N589e063bbf904b8d9b8d66b3d02ae970
105 N7978791f87e14943898ac04e05f579b0
106 Nc1fa818649eb4bc8b7173ab02d222466
107 schema:sameAs https://app.dimensions.ai/details/publication/pub.1138067817
108 https://doi.org/10.1007/s00467-021-05115-7
109 schema:sdDatePublished 2022-05-10T10:30
110 schema:sdLicense https://scigraph.springernature.com/explorer/license/
111 schema:sdPublisher Nc40b06233ddb446d80b4a8ba06d87353
112 schema:url https://doi.org/10.1007/s00467-021-05115-7
113 sgo:license sg:explorer/license/
114 sgo:sdDataset articles
115 rdf:type schema:ScholarlyArticle
116 N01108a82091849fa8da0fa8281cd17ba rdf:first sg:person.012302533312.63
117 rdf:rest rdf:nil
118 N016dfe5de61740409426147a102ebbd9 rdf:first sg:person.01112735663.13
119 rdf:rest N01108a82091849fa8da0fa8281cd17ba
120 N09c9672f3bd641a3be7d31525039b1cc rdf:first sg:person.010612274451.16
121 rdf:rest N0b1419bf7035401fab0136ee6da06a30
122 N0b1419bf7035401fab0136ee6da06a30 rdf:first sg:person.01316365041.17
123 rdf:rest Ne6a314e2fca444b5b8ef05a4f105219d
124 N13707957949946a689ae0631d2c8001e rdf:first sg:person.01060345462.48
125 rdf:rest Na79882dc6e6e49a7a98ae98ccb58ccbe
126 N43084d1f63834dcc968994f32d7a781e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
127 schema:name Child
128 rdf:type schema:DefinedTerm
129 N47e3583b2f4c4e9ebc873d4062260cc4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
130 schema:name Humans
131 rdf:type schema:DefinedTerm
132 N4faa36fca97146798ac1124d1e70be76 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
133 schema:name Male
134 rdf:type schema:DefinedTerm
135 N589e063bbf904b8d9b8d66b3d02ae970 schema:name dimensions_id
136 schema:value pub.1138067817
137 rdf:type schema:PropertyValue
138 N5c5ea04b942d400f9d45b9c6fc98fc52 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
139 schema:name Risk Factors
140 rdf:type schema:DefinedTerm
141 N7978791f87e14943898ac04e05f579b0 schema:name pubmed_id
142 schema:value 33988732
143 rdf:type schema:PropertyValue
144 N888e0bc365624333a9353ddbfe271bb6 rdf:first sg:person.01227352602.17
145 rdf:rest N8a2e26a563fa407e8094c610285d4bce
146 N8a2e26a563fa407e8094c610285d4bce rdf:first sg:person.01214356060.39
147 rdf:rest Nf8991c6713eb48608b450fd875f7188f
148 N966d97b9d61e4031ac4f4df542597b85 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
149 schema:name Nephrectomy
150 rdf:type schema:DefinedTerm
151 Na79882dc6e6e49a7a98ae98ccb58ccbe rdf:first sg:person.015722404651.24
152 rdf:rest Nf77dfce7fe0b478db32f344f4595af37
153 Nabd1f919da134689bd681a1b68488362 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
154 schema:name Retrospective Studies
155 rdf:type schema:DefinedTerm
156 Nc1fa818649eb4bc8b7173ab02d222466 schema:name doi
157 schema:value 10.1007/s00467-021-05115-7
158 rdf:type schema:PropertyValue
159 Nc3233b2d49ec4fe68cd168178d9cd9db schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
160 schema:name Female
161 rdf:type schema:DefinedTerm
162 Nc40b06233ddb446d80b4a8ba06d87353 schema:name Springer Nature - SN SciGraph project
163 rdf:type schema:Organization
164 Nc6aa0c3b199a4a1dbec2e77a4131078c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
165 schema:name Hypotension
166 rdf:type schema:DefinedTerm
167 Ndf3dfc7c29454646903ef154493c6322 schema:issueNumber 11
168 rdf:type schema:PublicationIssue
169 Ne6a314e2fca444b5b8ef05a4f105219d rdf:first sg:person.01174574062.16
170 rdf:rest N13707957949946a689ae0631d2c8001e
171 Nf77dfce7fe0b478db32f344f4595af37 rdf:first sg:person.01305716526.82
172 rdf:rest N888e0bc365624333a9353ddbfe271bb6
173 Nf8991c6713eb48608b450fd875f7188f rdf:first sg:person.0717317506.56
174 rdf:rest N016dfe5de61740409426147a102ebbd9
175 Nfded7e04380e415892d32cd6243edbc8 schema:volumeNumber 36
176 rdf:type schema:PublicationVolume
177 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
178 schema:name Medical and Health Sciences
179 rdf:type schema:DefinedTerm
180 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
181 schema:name Clinical Sciences
182 rdf:type schema:DefinedTerm
183 sg:journal.1097267 schema:issn 0931-041X
184 1432-198X
185 schema:name Pediatric Nephrology
186 schema:publisher Springer Nature
187 rdf:type schema:Periodical
188 sg:person.01060345462.48 schema:affiliation grid-institutes:grid.63906.3a
189 schema:familyName Sato
190 schema:givenName Mai
191 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01060345462.48
192 rdf:type schema:Person
193 sg:person.010612274451.16 schema:affiliation grid-institutes:grid.63906.3a
194 schema:familyName Nishi
195 schema:givenName Kentaro
196 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010612274451.16
197 rdf:type schema:Person
198 sg:person.01112735663.13 schema:affiliation grid-institutes:grid.410786.c
199 schema:familyName Ishikura
200 schema:givenName Kenji
201 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01112735663.13
202 rdf:type schema:Person
203 sg:person.01174574062.16 schema:affiliation grid-institutes:grid.63906.3a
204 schema:familyName Ogura
205 schema:givenName Masao
206 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01174574062.16
207 rdf:type schema:Person
208 sg:person.01214356060.39 schema:affiliation grid-institutes:grid.63906.3a
209 schema:familyName Matsumoto
210 schema:givenName Kimikazu
211 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01214356060.39
212 rdf:type schema:Person
213 sg:person.01227352602.17 schema:affiliation grid-institutes:grid.63906.3a
214 schema:familyName Kiyotani
215 schema:givenName Chikako
216 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01227352602.17
217 rdf:type schema:Person
218 sg:person.012302533312.63 schema:affiliation grid-institutes:grid.268441.d
219 schema:familyName Ito
220 schema:givenName Shuichi
221 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012302533312.63
222 rdf:type schema:Person
223 sg:person.01305716526.82 schema:affiliation grid-institutes:grid.63906.3a
224 schema:familyName Shioda
225 schema:givenName Yoko
226 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01305716526.82
227 rdf:type schema:Person
228 sg:person.01316365041.17 schema:affiliation grid-institutes:grid.63906.3a
229 schema:familyName Kamei
230 schema:givenName Koichi
231 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01316365041.17
232 rdf:type schema:Person
233 sg:person.015722404651.24 schema:affiliation grid-institutes:grid.410818.4
234 schema:familyName Ishiwa
235 schema:givenName Sho
236 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015722404651.24
237 rdf:type schema:Person
238 sg:person.0717317506.56 schema:affiliation grid-institutes:grid.31432.37
239 schema:familyName Nozu
240 schema:givenName Kandai
241 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0717317506.56
242 rdf:type schema:Person
243 sg:pub.10.1007/bf00445660 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044024908
244 https://doi.org/10.1007/bf00445660
245 rdf:type schema:CreativeWork
246 sg:pub.10.1007/bf00858984 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008028111
247 https://doi.org/10.1007/bf00858984
248 rdf:type schema:CreativeWork
249 sg:pub.10.1007/s00467-003-1131-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1075267267
250 https://doi.org/10.1007/s00467-003-1131-3
251 rdf:type schema:CreativeWork
252 sg:pub.10.1007/s00467-010-1656-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008902248
253 https://doi.org/10.1007/s00467-010-1656-1
254 rdf:type schema:CreativeWork
255 sg:pub.10.1007/s00467-012-2311-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046710337
256 https://doi.org/10.1007/s00467-012-2311-9
257 rdf:type schema:CreativeWork
258 sg:pub.10.1007/s00467-020-04578-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1127413042
259 https://doi.org/10.1007/s00467-020-04578-4
260 rdf:type schema:CreativeWork
261 sg:pub.10.1007/s004670100599 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027652486
262 https://doi.org/10.1007/s004670100599
263 rdf:type schema:CreativeWork
264 sg:pub.10.1007/s10157-019-01732-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1113301048
265 https://doi.org/10.1007/s10157-019-01732-7
266 rdf:type schema:CreativeWork
267 sg:pub.10.1038/s41598-020-71956-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1131251858
268 https://doi.org/10.1038/s41598-020-71956-1
269 rdf:type schema:CreativeWork
270 grid-institutes:grid.268441.d schema:alternateName Department of Pediatrics, Yokohama City University Graduate School of Medicine, Yokohama, Kanagawa, Japan
271 schema:name Department of Pediatrics, Yokohama City University Graduate School of Medicine, Yokohama, Kanagawa, Japan
272 Division of Nephrology and Rheumatology, National Center for Child Health and Development, 2-10-1, Okura, Setagaya-ku, 157-8535, Tokyo, Japan
273 rdf:type schema:Organization
274 grid-institutes:grid.31432.37 schema:alternateName Department of Pediatrics, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan
275 schema:name Department of Pediatrics, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan
276 rdf:type schema:Organization
277 grid-institutes:grid.410786.c schema:alternateName Department of Pediatrics, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan
278 schema:name Department of Pediatrics, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan
279 Division of Nephrology and Rheumatology, National Center for Child Health and Development, 2-10-1, Okura, Setagaya-ku, 157-8535, Tokyo, Japan
280 rdf:type schema:Organization
281 grid-institutes:grid.410818.4 schema:alternateName Department of Pediatric Nephrology, Tokyo Women’s Medical University, Tokyo, Japan
282 schema:name Department of Pediatric Nephrology, Tokyo Women’s Medical University, Tokyo, Japan
283 Division of Nephrology and Rheumatology, National Center for Child Health and Development, 2-10-1, Okura, Setagaya-ku, 157-8535, Tokyo, Japan
284 rdf:type schema:Organization
285 grid-institutes:grid.63906.3a schema:alternateName Children’s Cancer Center, National Center for Child Health and Development, Tokyo, Japan
286 Division of Nephrology and Rheumatology, National Center for Child Health and Development, 2-10-1, Okura, Setagaya-ku, 157-8535, Tokyo, Japan
287 schema:name Children’s Cancer Center, National Center for Child Health and Development, Tokyo, Japan
288 Division of Nephrology and Rheumatology, National Center for Child Health and Development, 2-10-1, Okura, Setagaya-ku, 157-8535, Tokyo, Japan
289 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...