Hypertension and childhood stroke View Full Text


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Article Info

DATE

2020-04-29

AUTHORS

Juan C. Kupferman, Marc B. Lande, Stella Stabouli, Dimitrios I. Zafeiriou, Steven G. Pavlakis

ABSTRACT

Cerebrovascular disease (stroke) is one of the ten leading causes of death in children and adolescents. Multiple etiologies, from arteriopathies to prothrombic states, can cause stroke in youth. In adult stroke, hypertension has been shown to be the single most important modifiable risk factor. Although hypertension has not been strongly identified as a risk factor in childhood stroke to date, there is preliminary evidence that suggests that hypertension may also be associated with stroke in children. In this review, we summarize the literature that may link hypertension to stroke in the young. We have identified a series of barriers and limitations in the fields of pediatric hypertension and pediatric neurology that might explain why hypertension has been overlooked in childhood stroke. We suggest that hypertension may be a relevant risk factor that, alone or in combination with other multiple factors, contributes to the development of stroke in children. Currently, there are no consensus guidelines for the management of post-stroke hypertension in children. Thus, we recommend that blood pressure be assessed carefully in every child presenting with acute stroke in order to better understand the effects of hypertension in the development and the outcome of childhood stroke. We suggest a treatment algorithm to help practitioners manage hypertension after a stroke. More... »

PAGES

809-823

References to SciGraph publications

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  • 2012-06-13. Primary hypertension and neurocognitive and executive functioning in school-age children in PEDIATRIC NEPHROLOGY
  • 2011-03-08. Challenges in the diagnosis and treatment of pediatric stroke in NATURE REVIEWS NEUROLOGY
  • 2016-06-27. Hypertension, Stroke and Abdominal Bruit: A Cryptic Extracranial Moyamoya! in INDIAN JOURNAL OF PEDIATRICS
  • 2012-08-11. Masked hypertension is prevalent in children with sickle cell disease: a Midwest Pediatric Nephrology Consortium study in PEDIATRIC NEPHROLOGY
  • 2014-01-04. Arterial Ischemic Stroke in Children: Risk Factors and Etiologies in CURRENT NEUROLOGY AND NEUROSCIENCE REPORTS
  • 2010-04-15. Improvement of left ventricular mass with antihypertensive therapy in children with hypertension in PEDIATRIC NEPHROLOGY
  • 2015-10-27. Hypertension in late adolescence and cardiovascular mortality in midlife: a cohort study of 2.3 million 16- to 19-year-old examinees in PEDIATRIC NEPHROLOGY
  • 2015-09-28. Can office blood pressure readings predict masked hypertension? in PEDIATRIC NEPHROLOGY
  • 2004-08-19. A 4-year-old girl with autosomal dominant polycystic kidney disease complicated by a ruptured intracranial aneurysm in EUROPEAN JOURNAL OF PEDIATRICS
  • 2001-07-01. Moyamoya disease associated with renovascular disease in a young African-Brazilian patient in JOURNAL OF HUMAN HYPERTENSION
  • 2020-02-24. Increased history of ischemic stroke and decreased neurocognitive performance in children with chronic kidney disease in PEDIATRIC NEPHROLOGY
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s00467-020-04550-2

    DOI

    http://dx.doi.org/10.1007/s00467-020-04550-2

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1127246943

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/32350664


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