Efficacy of low-dose daily versus alternate-day prednisolone in frequently relapsing nephrotic syndrome: an open-label randomized controlled trial View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2019-05

AUTHORS

Menka Yadav, Aditi Sinha, Priyanka Khandelwal, Pankaj Hari, Arvind Bagga

ABSTRACT

BACKGROUND: While patients with frequently relapsing nephrotic syndrome (FRNS) are initially treated with long-term alternate-day prednisolone, relapses and adverse effects are common. In an open-label randomized controlled trial, we compared the efficacy of therapy with low-dose daily to standard alternate-day prednisolone in reducing relapse rates over 12-month follow-up. METHODS: Consecutive patients, aged 2-18 years, with FRNS were included. Following therapy of relapse, prednisolone was tapered to 0.75 mg/kg on alternate days. Stratifying for steroid dependence, patients were randomly assigned to prednisolone at 0.2-0.3 mg/kg daily or 0.5-0.7 mg/kg alternate day for 12 months. Relapses were treated with daily prednisolone, followed by return to intervention. Primary outcome was the incidence of relapses. Proportion with therapy failure (≥ 2 relapses in any 6 months or significant steroid toxicity) and sustained remission, cumulative prednisolone intake and adverse events were evaluated. RESULTS: Patients receiving daily prednisolone (n = 30) showed significantly fewer relapses than those on alternate-day therapy (n = 31) (0.55 relapses/person-year versus 1.94 relapses/person-year; incidence rate ratio 0.28; 95% CI 0.15, 0.52). Daily therapy was associated with higher rates of sustained remission at 6 months (73.3 versus 48.4%) and 1 year (60 versus 31.6%; log rank p = 0.013), lower rates of treatment failure at 6 months (3.3 versus 32.8%) and 1 year (6.7 versus 57.4%; p < 0.0001), and lower prednisolone use (0.27 ± 0.07 versus 0.39 ± 0.19 mg/kg/day; p = 0.003). Three and two patients need to receive the study intervention to enable sustained remission and prevent treatment failure, respectively. CONCLUSIONS: In patients with FRNS, daily administration of low-dose prednisolone is more effective than standard-dose alternate day therapy in lowering relapse rates, sustaining remission, and enabling steroid sparing. More... »

PAGES

829-835

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00467-018-4071-7

DOI

http://dx.doi.org/10.1007/s00467-018-4071-7

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1106835738

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30194663


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "All India Institute of Medical Sciences", 
          "id": "https://www.grid.ac/institutes/grid.413618.9", 
          "name": [
            "Division of Nephrology, Department of Pediatrics, All India Institute of Medical Sciences, 110029, New Delhi, India"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Yadav", 
        "givenName": "Menka", 
        "id": "sg:person.010351151207.27", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010351151207.27"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "All India Institute of Medical Sciences", 
          "id": "https://www.grid.ac/institutes/grid.413618.9", 
          "name": [
            "Division of Nephrology, Department of Pediatrics, All India Institute of Medical Sciences, 110029, New Delhi, India"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sinha", 
        "givenName": "Aditi", 
        "id": "sg:person.01050672111.97", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01050672111.97"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "All India Institute of Medical Sciences", 
          "id": "https://www.grid.ac/institutes/grid.413618.9", 
          "name": [
            "Division of Nephrology, Department of Pediatrics, All India Institute of Medical Sciences, 110029, New Delhi, India"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Khandelwal", 
        "givenName": "Priyanka", 
        "id": "sg:person.01011760110.30", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01011760110.30"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "All India Institute of Medical Sciences", 
          "id": "https://www.grid.ac/institutes/grid.413618.9", 
          "name": [
            "Division of Nephrology, Department of Pediatrics, All India Institute of Medical Sciences, 110029, New Delhi, India"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hari", 
        "givenName": "Pankaj", 
        "id": "sg:person.01165120511.94", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01165120511.94"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "All India Institute of Medical Sciences", 
          "id": "https://www.grid.ac/institutes/grid.413618.9", 
          "name": [
            "Division of Nephrology, Department of Pediatrics, All India Institute of Medical Sciences, 110029, New Delhi, India"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Bagga", 
        "givenName": "Arvind", 
        "id": "sg:person.0672171411.29", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0672171411.29"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1136/adc.2007.116079", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001746701"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0022-3476(79)80660-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005613490"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s13312-012-0220-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005682648", 
          "https://doi.org/10.1007/s13312-012-0220-4"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/14651858.cd001533.pub5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013626740"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0022-3476(83)80260-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013687934"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/kisup.2012.16", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013813359", 
          "https://doi.org/10.1038/kisup.2012.16"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(77)90726-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014745494"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(77)90726-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014745494"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2215/cjn.01850310", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016397841"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1681/asn.2008030287", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017212383"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1681/asn.2008030287", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017212383"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00431-014-2479-z", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017961393", 
          "https://doi.org/10.1007/s00431-014-2479-z"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s13052-015-0123-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020313390", 
          "https://doi.org/10.1186/s13052-015-0123-9"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s13052-015-0123-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020313390", 
          "https://doi.org/10.1186/s13052-015-0123-9"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/adc.2006.108985", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027020822"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00442096", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027728225", 
          "https://doi.org/10.1007/bf00442096"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00442096", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027728225", 
          "https://doi.org/10.1007/bf00442096"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1651-2227.1990.tb11461.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030146675"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2215/cjn.05691108", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031173083"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/adc.70.2.151", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035346680"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1159/000045684", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044470042"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/bmj.1.6117.892", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045432536"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00467-003-1176-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046076042", 
          "https://doi.org/10.1007/s00467-003-1176-3"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0022-3476(83)80582-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046274753"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00878359", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046342582", 
          "https://doi.org/10.1007/bf00878359"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1177/000992288802700807", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1063564261"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1177/000992288802700807", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1063564261"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1542/peds.114.2.s2.555", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1067822962"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2471/blt.07.043497", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1070836960"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1077624588", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1077955865", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1081644781", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2019-05", 
    "datePublishedReg": "2019-05-01", 
    "description": "BACKGROUND: While patients with frequently relapsing nephrotic syndrome (FRNS) are initially treated with long-term alternate-day prednisolone, relapses and adverse effects are common. In an open-label randomized controlled trial, we compared the efficacy of therapy with low-dose daily to standard alternate-day prednisolone in reducing relapse rates over 12-month follow-up.\nMETHODS: Consecutive patients, aged 2-18\u00a0years, with FRNS were included. Following therapy of relapse, prednisolone was tapered to 0.75\u00a0mg/kg on alternate days. Stratifying for steroid dependence, patients were randomly assigned to prednisolone at 0.2-0.3\u00a0mg/kg daily or 0.5-0.7\u00a0mg/kg alternate day for 12\u00a0months. Relapses were treated with daily prednisolone, followed by return to intervention. Primary outcome was the incidence of relapses. Proportion with therapy failure (\u2265\u20092 relapses in any 6\u00a0months or significant steroid toxicity) and sustained remission, cumulative prednisolone intake and adverse events were evaluated.\nRESULTS: Patients receiving daily prednisolone (n\u2009=\u200930) showed significantly fewer relapses than those on alternate-day therapy (n\u2009=\u200931) (0.55 relapses/person-year versus 1.94 relapses/person-year; incidence rate ratio 0.28; 95% CI 0.15, 0.52). Daily therapy was associated with higher rates of sustained remission at 6\u00a0months (73.3 versus 48.4%) and 1\u00a0year (60 versus 31.6%; log rank p\u2009=\u20090.013), lower rates of treatment failure at 6\u00a0months (3.3 versus 32.8%) and 1\u00a0year (6.7 versus 57.4%; p\u2009<\u20090.0001), and lower prednisolone use (0.27\u2009\u00b1\u20090.07 versus 0.39\u2009\u00b1\u20090.19\u00a0mg/kg/day; p\u2009=\u20090.003). Three and two patients need to receive the study intervention to enable sustained remission and prevent treatment failure, respectively.\nCONCLUSIONS: In patients with FRNS, daily administration of low-dose prednisolone is more effective than standard-dose alternate day therapy in lowering relapse rates, sustaining remission, and enabling steroid sparing.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s00467-018-4071-7", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1097267", 
        "issn": [
          "0931-041X", 
          "1432-198X"
        ], 
        "name": "Pediatric Nephrology", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "5", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "34"
      }
    ], 
    "name": "Efficacy of low-dose daily versus alternate-day prednisolone in frequently relapsing nephrotic syndrome: an open-label randomized controlled trial", 
    "pagination": "829-835", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "112aa145b81fca6f3f927281e26f9e736e8a80d1837d1749fd0a3c8c0b401faa"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "30194663"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "8708728"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s00467-018-4071-7"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1106835738"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s00467-018-4071-7", 
      "https://app.dimensions.ai/details/publication/pub.1106835738"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T13:19", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000368_0000000368/records_78956_00000001.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://link.springer.com/10.1007%2Fs00467-018-4071-7"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00467-018-4071-7'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00467-018-4071-7'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00467-018-4071-7'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00467-018-4071-7'


 

This table displays all metadata directly associated to this object as RDF triples.

182 TRIPLES      21 PREDICATES      56 URIs      21 LITERALS      9 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s00467-018-4071-7 schema:about anzsrc-for:11
2 anzsrc-for:1103
3 schema:author Na3346eabf91f43218eeb4ac49f45a16b
4 schema:citation sg:pub.10.1007/bf00442096
5 sg:pub.10.1007/bf00878359
6 sg:pub.10.1007/s00431-014-2479-z
7 sg:pub.10.1007/s00467-003-1176-3
8 sg:pub.10.1007/s13312-012-0220-4
9 sg:pub.10.1038/kisup.2012.16
10 sg:pub.10.1186/s13052-015-0123-9
11 https://app.dimensions.ai/details/publication/pub.1077624588
12 https://app.dimensions.ai/details/publication/pub.1077955865
13 https://app.dimensions.ai/details/publication/pub.1081644781
14 https://doi.org/10.1002/14651858.cd001533.pub5
15 https://doi.org/10.1016/s0022-3476(79)80660-5
16 https://doi.org/10.1016/s0022-3476(83)80260-1
17 https://doi.org/10.1016/s0022-3476(83)80582-4
18 https://doi.org/10.1016/s0140-6736(77)90726-7
19 https://doi.org/10.1111/j.1651-2227.1990.tb11461.x
20 https://doi.org/10.1136/adc.2006.108985
21 https://doi.org/10.1136/adc.2007.116079
22 https://doi.org/10.1136/adc.70.2.151
23 https://doi.org/10.1136/bmj.1.6117.892
24 https://doi.org/10.1159/000045684
25 https://doi.org/10.1177/000992288802700807
26 https://doi.org/10.1542/peds.114.2.s2.555
27 https://doi.org/10.1681/asn.2008030287
28 https://doi.org/10.2215/cjn.01850310
29 https://doi.org/10.2215/cjn.05691108
30 https://doi.org/10.2471/blt.07.043497
31 schema:datePublished 2019-05
32 schema:datePublishedReg 2019-05-01
33 schema:description BACKGROUND: While patients with frequently relapsing nephrotic syndrome (FRNS) are initially treated with long-term alternate-day prednisolone, relapses and adverse effects are common. In an open-label randomized controlled trial, we compared the efficacy of therapy with low-dose daily to standard alternate-day prednisolone in reducing relapse rates over 12-month follow-up. METHODS: Consecutive patients, aged 2-18 years, with FRNS were included. Following therapy of relapse, prednisolone was tapered to 0.75 mg/kg on alternate days. Stratifying for steroid dependence, patients were randomly assigned to prednisolone at 0.2-0.3 mg/kg daily or 0.5-0.7 mg/kg alternate day for 12 months. Relapses were treated with daily prednisolone, followed by return to intervention. Primary outcome was the incidence of relapses. Proportion with therapy failure (≥ 2 relapses in any 6 months or significant steroid toxicity) and sustained remission, cumulative prednisolone intake and adverse events were evaluated. RESULTS: Patients receiving daily prednisolone (n = 30) showed significantly fewer relapses than those on alternate-day therapy (n = 31) (0.55 relapses/person-year versus 1.94 relapses/person-year; incidence rate ratio 0.28; 95% CI 0.15, 0.52). Daily therapy was associated with higher rates of sustained remission at 6 months (73.3 versus 48.4%) and 1 year (60 versus 31.6%; log rank p = 0.013), lower rates of treatment failure at 6 months (3.3 versus 32.8%) and 1 year (6.7 versus 57.4%; p < 0.0001), and lower prednisolone use (0.27 ± 0.07 versus 0.39 ± 0.19 mg/kg/day; p = 0.003). Three and two patients need to receive the study intervention to enable sustained remission and prevent treatment failure, respectively. CONCLUSIONS: In patients with FRNS, daily administration of low-dose prednisolone is more effective than standard-dose alternate day therapy in lowering relapse rates, sustaining remission, and enabling steroid sparing.
34 schema:genre research_article
35 schema:inLanguage en
36 schema:isAccessibleForFree false
37 schema:isPartOf N10425939343f401a8701ab4b9b921222
38 Nda883d7095a948c19fdea165023aeca1
39 sg:journal.1097267
40 schema:name Efficacy of low-dose daily versus alternate-day prednisolone in frequently relapsing nephrotic syndrome: an open-label randomized controlled trial
41 schema:pagination 829-835
42 schema:productId N2677cc1e60484af8ab15aec375bea055
43 N5725f1242dae4f96a4c62db455ff9beb
44 N9d22b35534934b0b99ec3783327c4a3b
45 Na4ef4f1f3352416e9174f51cb79cbca0
46 Na95329f5635046d48ff9be71c098aa96
47 schema:sameAs https://app.dimensions.ai/details/publication/pub.1106835738
48 https://doi.org/10.1007/s00467-018-4071-7
49 schema:sdDatePublished 2019-04-11T13:19
50 schema:sdLicense https://scigraph.springernature.com/explorer/license/
51 schema:sdPublisher N9023e58a2fe44eaeafec8ea906b0f9cc
52 schema:url https://link.springer.com/10.1007%2Fs00467-018-4071-7
53 sgo:license sg:explorer/license/
54 sgo:sdDataset articles
55 rdf:type schema:ScholarlyArticle
56 N040dbfd7b058496aadaf53dbf309a131 rdf:first sg:person.0672171411.29
57 rdf:rest rdf:nil
58 N10425939343f401a8701ab4b9b921222 schema:issueNumber 5
59 rdf:type schema:PublicationIssue
60 N2677cc1e60484af8ab15aec375bea055 schema:name dimensions_id
61 schema:value pub.1106835738
62 rdf:type schema:PropertyValue
63 N4c19d6eb7c6b448d8012f2d4d79c8605 rdf:first sg:person.01165120511.94
64 rdf:rest N040dbfd7b058496aadaf53dbf309a131
65 N5725f1242dae4f96a4c62db455ff9beb schema:name readcube_id
66 schema:value 112aa145b81fca6f3f927281e26f9e736e8a80d1837d1749fd0a3c8c0b401faa
67 rdf:type schema:PropertyValue
68 N80d10e8f2d254f99975b20e549aeeed2 rdf:first sg:person.01011760110.30
69 rdf:rest N4c19d6eb7c6b448d8012f2d4d79c8605
70 N9023e58a2fe44eaeafec8ea906b0f9cc schema:name Springer Nature - SN SciGraph project
71 rdf:type schema:Organization
72 N9d22b35534934b0b99ec3783327c4a3b schema:name pubmed_id
73 schema:value 30194663
74 rdf:type schema:PropertyValue
75 Na3346eabf91f43218eeb4ac49f45a16b rdf:first sg:person.010351151207.27
76 rdf:rest Nfecd1bd684c24ebf9cd86a6e1832be86
77 Na4ef4f1f3352416e9174f51cb79cbca0 schema:name nlm_unique_id
78 schema:value 8708728
79 rdf:type schema:PropertyValue
80 Na95329f5635046d48ff9be71c098aa96 schema:name doi
81 schema:value 10.1007/s00467-018-4071-7
82 rdf:type schema:PropertyValue
83 Nda883d7095a948c19fdea165023aeca1 schema:volumeNumber 34
84 rdf:type schema:PublicationVolume
85 Nfecd1bd684c24ebf9cd86a6e1832be86 rdf:first sg:person.01050672111.97
86 rdf:rest N80d10e8f2d254f99975b20e549aeeed2
87 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
88 schema:name Medical and Health Sciences
89 rdf:type schema:DefinedTerm
90 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
91 schema:name Clinical Sciences
92 rdf:type schema:DefinedTerm
93 sg:journal.1097267 schema:issn 0931-041X
94 1432-198X
95 schema:name Pediatric Nephrology
96 rdf:type schema:Periodical
97 sg:person.01011760110.30 schema:affiliation https://www.grid.ac/institutes/grid.413618.9
98 schema:familyName Khandelwal
99 schema:givenName Priyanka
100 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01011760110.30
101 rdf:type schema:Person
102 sg:person.010351151207.27 schema:affiliation https://www.grid.ac/institutes/grid.413618.9
103 schema:familyName Yadav
104 schema:givenName Menka
105 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010351151207.27
106 rdf:type schema:Person
107 sg:person.01050672111.97 schema:affiliation https://www.grid.ac/institutes/grid.413618.9
108 schema:familyName Sinha
109 schema:givenName Aditi
110 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01050672111.97
111 rdf:type schema:Person
112 sg:person.01165120511.94 schema:affiliation https://www.grid.ac/institutes/grid.413618.9
113 schema:familyName Hari
114 schema:givenName Pankaj
115 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01165120511.94
116 rdf:type schema:Person
117 sg:person.0672171411.29 schema:affiliation https://www.grid.ac/institutes/grid.413618.9
118 schema:familyName Bagga
119 schema:givenName Arvind
120 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0672171411.29
121 rdf:type schema:Person
122 sg:pub.10.1007/bf00442096 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027728225
123 https://doi.org/10.1007/bf00442096
124 rdf:type schema:CreativeWork
125 sg:pub.10.1007/bf00878359 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046342582
126 https://doi.org/10.1007/bf00878359
127 rdf:type schema:CreativeWork
128 sg:pub.10.1007/s00431-014-2479-z schema:sameAs https://app.dimensions.ai/details/publication/pub.1017961393
129 https://doi.org/10.1007/s00431-014-2479-z
130 rdf:type schema:CreativeWork
131 sg:pub.10.1007/s00467-003-1176-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046076042
132 https://doi.org/10.1007/s00467-003-1176-3
133 rdf:type schema:CreativeWork
134 sg:pub.10.1007/s13312-012-0220-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005682648
135 https://doi.org/10.1007/s13312-012-0220-4
136 rdf:type schema:CreativeWork
137 sg:pub.10.1038/kisup.2012.16 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013813359
138 https://doi.org/10.1038/kisup.2012.16
139 rdf:type schema:CreativeWork
140 sg:pub.10.1186/s13052-015-0123-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020313390
141 https://doi.org/10.1186/s13052-015-0123-9
142 rdf:type schema:CreativeWork
143 https://app.dimensions.ai/details/publication/pub.1077624588 schema:CreativeWork
144 https://app.dimensions.ai/details/publication/pub.1077955865 schema:CreativeWork
145 https://app.dimensions.ai/details/publication/pub.1081644781 schema:CreativeWork
146 https://doi.org/10.1002/14651858.cd001533.pub5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013626740
147 rdf:type schema:CreativeWork
148 https://doi.org/10.1016/s0022-3476(79)80660-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005613490
149 rdf:type schema:CreativeWork
150 https://doi.org/10.1016/s0022-3476(83)80260-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013687934
151 rdf:type schema:CreativeWork
152 https://doi.org/10.1016/s0022-3476(83)80582-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046274753
153 rdf:type schema:CreativeWork
154 https://doi.org/10.1016/s0140-6736(77)90726-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014745494
155 rdf:type schema:CreativeWork
156 https://doi.org/10.1111/j.1651-2227.1990.tb11461.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1030146675
157 rdf:type schema:CreativeWork
158 https://doi.org/10.1136/adc.2006.108985 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027020822
159 rdf:type schema:CreativeWork
160 https://doi.org/10.1136/adc.2007.116079 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001746701
161 rdf:type schema:CreativeWork
162 https://doi.org/10.1136/adc.70.2.151 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035346680
163 rdf:type schema:CreativeWork
164 https://doi.org/10.1136/bmj.1.6117.892 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045432536
165 rdf:type schema:CreativeWork
166 https://doi.org/10.1159/000045684 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044470042
167 rdf:type schema:CreativeWork
168 https://doi.org/10.1177/000992288802700807 schema:sameAs https://app.dimensions.ai/details/publication/pub.1063564261
169 rdf:type schema:CreativeWork
170 https://doi.org/10.1542/peds.114.2.s2.555 schema:sameAs https://app.dimensions.ai/details/publication/pub.1067822962
171 rdf:type schema:CreativeWork
172 https://doi.org/10.1681/asn.2008030287 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017212383
173 rdf:type schema:CreativeWork
174 https://doi.org/10.2215/cjn.01850310 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016397841
175 rdf:type schema:CreativeWork
176 https://doi.org/10.2215/cjn.05691108 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031173083
177 rdf:type schema:CreativeWork
178 https://doi.org/10.2471/blt.07.043497 schema:sameAs https://app.dimensions.ai/details/publication/pub.1070836960
179 rdf:type schema:CreativeWork
180 https://www.grid.ac/institutes/grid.413618.9 schema:alternateName All India Institute of Medical Sciences
181 schema:name Division of Nephrology, Department of Pediatrics, All India Institute of Medical Sciences, 110029, New Delhi, India
182 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...