Histochemical and immunohistochemical study of the glomerular development in human fetuses View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2007-11-08

AUTHORS

Mara Lúcia Fonseca Ferraz, Aline Mara dos Santos, Camila Lourencini Cavellani, Renata Calciolari Rossi, Rosana Rosa Miranda Corrêa, Marlene Antônia dos Reis, Vicente de Paula Antunes Teixeira, Eumenia Costa da Cunha Castro

ABSTRACT

Few studies exist that establish the normal morphological patterns of glomerular development, though this is one of the organs that continues to evolve morphologically during the postnatal period up to 4 weeks after birth. In our study one kidney from each autopsy of a total of 86 autopsies was analyzed [15 weeks to 40 weeks of gestational age (GA)]. We examined the variation in the nephrogenic zone thickness, the area and diameter of the glomerular tuft, the area and diameter of the glomerular capsule, and the immunohistochemical markers, anti-CD31 and anti-CD34 antibodies, which accompany the development of the glomerular microvasculature. Periodic acid–methenamine silver (PAMS) stain was used for the morphological and morphometrical analyses, and it was particularly useful in fetuses in which autolysis had occurred. The length of the nephrogenic zone (NZ) decreased with the increase of the GA (P < 0.001) according to the formula: \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${\text{GA}} = 36.5 - {\left( {0.05 \times {\text{length of NZ}}} \right)}$$\end{document}. The areas of the Bowman capsule (P < 0.0001), the capillary tuft (P < 0.0001), and the capillary tuft diameter (P = 0.00393) of the intermediary glomeruli increased with the advance of GA, with a positive significant correlation. The same parameters of the juxtamedullary and superficial glomeruli had no correlation with the advance of GA. The cells of the primary structures in the “S” shape of the primitive nephrons were negative for CD31 and CD34. Staining for both antibodies was found, for all GAs, in the endothelial cells of the mature glomeruli tuft and in the renal interstitial vessels. The data obtained in this work contribute to the evaluation of renal maturity in autopsied fetuses and are particularly important in fetuses when autolysis has occurred, to which the parameters used in this study can also be applied. The establishment of normal morphometric and immunohistochemical parameters for the evaluation of renal maturity increases the diagnostic precision of renal pathological alterations in aborted material and perinatal autopsy. More... »

PAGES

257-262

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00467-007-0654-4

DOI

http://dx.doi.org/10.1007/s00467-007-0654-4

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1034165342

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/17990004


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Biomarkers", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Fetal Development", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Fluorescent Antibody Technique, Indirect", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Gestational Age", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Glycogen", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Kidney", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Kidney Glomerulus", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Periodic Acid-Schiff Reaction", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Retrospective Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Silver Staining", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Biological Sciences Department, General Pathology Discipline, Tri\u00e2ngulo Mineiro Federal University, Rua Frei Paulino 30, Bairro Abadia. Cep 38025-180, Uberaba, Minas Gerais, Brazil", 
          "id": "http://www.grid.ac/institutes/grid.411281.f", 
          "name": [
            "Biological Sciences Department, General Pathology Discipline, Tri\u00e2ngulo Mineiro Federal University, Rua Frei Paulino 30, Bairro Abadia. Cep 38025-180, Uberaba, Minas Gerais, Brazil"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Fonseca Ferraz", 
        "givenName": "Mara L\u00facia", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Biological Sciences Department, General Pathology Discipline, Tri\u00e2ngulo Mineiro Federal University, Rua Frei Paulino 30, Bairro Abadia. Cep 38025-180, Uberaba, Minas Gerais, Brazil", 
          "id": "http://www.grid.ac/institutes/grid.411281.f", 
          "name": [
            "Biological Sciences Department, General Pathology Discipline, Tri\u00e2ngulo Mineiro Federal University, Rua Frei Paulino 30, Bairro Abadia. Cep 38025-180, Uberaba, Minas Gerais, Brazil"
          ], 
          "type": "Organization"
        }, 
        "familyName": "dos Santos", 
        "givenName": "Aline Mara", 
        "id": "sg:person.0773451024.09", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0773451024.09"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Biological Sciences Department, General Pathology Discipline, Tri\u00e2ngulo Mineiro Federal University, Rua Frei Paulino 30, Bairro Abadia. Cep 38025-180, Uberaba, Minas Gerais, Brazil", 
          "id": "http://www.grid.ac/institutes/grid.411281.f", 
          "name": [
            "Biological Sciences Department, General Pathology Discipline, Tri\u00e2ngulo Mineiro Federal University, Rua Frei Paulino 30, Bairro Abadia. Cep 38025-180, Uberaba, Minas Gerais, Brazil"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Cavellani", 
        "givenName": "Camila Lourencini", 
        "id": "sg:person.01041564224.95", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01041564224.95"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Biological Sciences Department, General Pathology Discipline, Tri\u00e2ngulo Mineiro Federal University, Rua Frei Paulino 30, Bairro Abadia. Cep 38025-180, Uberaba, Minas Gerais, Brazil", 
          "id": "http://www.grid.ac/institutes/grid.411281.f", 
          "name": [
            "Biological Sciences Department, General Pathology Discipline, Tri\u00e2ngulo Mineiro Federal University, Rua Frei Paulino 30, Bairro Abadia. Cep 38025-180, Uberaba, Minas Gerais, Brazil"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Rossi", 
        "givenName": "Renata Calciolari", 
        "id": "sg:person.01272273127.73", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01272273127.73"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Biological Sciences Department, General Pathology Discipline, Tri\u00e2ngulo Mineiro Federal University, Rua Frei Paulino 30, Bairro Abadia. Cep 38025-180, Uberaba, Minas Gerais, Brazil", 
          "id": "http://www.grid.ac/institutes/grid.411281.f", 
          "name": [
            "Biological Sciences Department, General Pathology Discipline, Tri\u00e2ngulo Mineiro Federal University, Rua Frei Paulino 30, Bairro Abadia. Cep 38025-180, Uberaba, Minas Gerais, Brazil"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Corr\u00eaa", 
        "givenName": "Rosana Rosa Miranda", 
        "id": "sg:person.01035121507.51", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01035121507.51"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Biological Sciences Department, General Pathology Discipline, Tri\u00e2ngulo Mineiro Federal University, Rua Frei Paulino 30, Bairro Abadia. Cep 38025-180, Uberaba, Minas Gerais, Brazil", 
          "id": "http://www.grid.ac/institutes/grid.411281.f", 
          "name": [
            "Biological Sciences Department, General Pathology Discipline, Tri\u00e2ngulo Mineiro Federal University, Rua Frei Paulino 30, Bairro Abadia. Cep 38025-180, Uberaba, Minas Gerais, Brazil"
          ], 
          "type": "Organization"
        }, 
        "familyName": "dos Reis", 
        "givenName": "Marlene Ant\u00f4nia", 
        "id": "sg:person.01224126024.60", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01224126024.60"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Biological Sciences Department, General Pathology Discipline, Tri\u00e2ngulo Mineiro Federal University, Rua Frei Paulino 30, Bairro Abadia. Cep 38025-180, Uberaba, Minas Gerais, Brazil", 
          "id": "http://www.grid.ac/institutes/grid.411281.f", 
          "name": [
            "Biological Sciences Department, General Pathology Discipline, Tri\u00e2ngulo Mineiro Federal University, Rua Frei Paulino 30, Bairro Abadia. Cep 38025-180, Uberaba, Minas Gerais, Brazil"
          ], 
          "type": "Organization"
        }, 
        "familyName": "de Paula Antunes Teixeira", 
        "givenName": "Vicente", 
        "id": "sg:person.014127114354.44", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014127114354.44"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Biological Sciences Department, General Pathology Discipline, Tri\u00e2ngulo Mineiro Federal University, Rua Frei Paulino 30, Bairro Abadia. Cep 38025-180, Uberaba, Minas Gerais, Brazil", 
          "id": "http://www.grid.ac/institutes/grid.411281.f", 
          "name": [
            "Biological Sciences Department, General Pathology Discipline, Tri\u00e2ngulo Mineiro Federal University, Rua Frei Paulino 30, Bairro Abadia. Cep 38025-180, Uberaba, Minas Gerais, Brazil"
          ], 
          "type": "Organization"
        }, 
        "familyName": "da Cunha Castro", 
        "givenName": "Eumenia Costa", 
        "id": "sg:person.014255222026.69", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014255222026.69"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1038/sj.jp.7211608", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002222470", 
          "https://doi.org/10.1038/sj.jp.7211608"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s002040050165", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017889105", 
          "https://doi.org/10.1007/s002040050165"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf02898441", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038864066", 
          "https://doi.org/10.1007/bf02898441"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2007-11-08", 
    "datePublishedReg": "2007-11-08", 
    "description": "Few studies exist that establish the normal morphological patterns of glomerular development, though this is one of the organs that continues to evolve morphologically during the postnatal period up to 4\u00a0weeks after birth. In our study one kidney from each autopsy of a total of 86 autopsies was analyzed [15\u00a0weeks to 40\u00a0weeks of gestational age (GA)]. We examined the variation in the nephrogenic zone thickness, the area and diameter of the glomerular tuft, the area and diameter of the glomerular capsule, and the immunohistochemical markers, anti-CD31 and anti-CD34 antibodies, which accompany the development of the glomerular microvasculature. Periodic acid\u2013methenamine silver (PAMS) stain was used for the morphological and morphometrical analyses, and it was particularly useful in fetuses in which autolysis had occurred. The length of the nephrogenic zone (NZ) decreased with the increase of the GA (P\u2009<\u20090.001) according to the formula: \\documentclass[12pt]{minimal}\n\t\t\t\t\\usepackage{amsmath}\n\t\t\t\t\\usepackage{wasysym}\n\t\t\t\t\\usepackage{amsfonts}\n\t\t\t\t\\usepackage{amssymb}\n\t\t\t\t\\usepackage{amsbsy}\n\t\t\t\t\\usepackage{mathrsfs}\n\t\t\t\t\\usepackage{upgreek}\n\t\t\t\t\\setlength{\\oddsidemargin}{-69pt}\n\t\t\t\t\\begin{document}$${\\text{GA}} = 36.5 - {\\left( {0.05 \\times {\\text{length of NZ}}} \\right)}$$\\end{document}. The areas of the Bowman capsule (P\u2009<\u20090.0001), the capillary tuft (P\u2009<\u20090.0001), and the capillary tuft diameter (P\u2009=\u20090.00393) of the intermediary glomeruli increased with the advance of GA, with a positive significant correlation. The same parameters of the juxtamedullary and superficial glomeruli had no correlation with the advance of GA. The cells of the primary structures in the \u201cS\u201d shape of the primitive nephrons were negative for CD31 and CD34. Staining for both antibodies was found, for all GAs, in the endothelial cells of the mature glomeruli tuft and in the renal interstitial vessels. The data obtained in this work contribute to the evaluation of renal maturity in autopsied fetuses and are particularly important in fetuses when autolysis has occurred, to which the parameters used in this study can also be applied. The establishment of normal morphometric and immunohistochemical parameters for the evaluation of renal maturity increases the diagnostic precision of renal pathological alterations in aborted material and perinatal autopsy.", 
    "genre": "article", 
    "id": "sg:pub.10.1007/s00467-007-0654-4", 
    "inLanguage": "en", 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1097267", 
        "issn": [
          "0931-041X", 
          "1432-198X"
        ], 
        "name": "Pediatric Nephrology", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "2", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "23"
      }
    ], 
    "keywords": [
      "renal maturity", 
      "renal pathological alterations", 
      "nephrogenic zone", 
      "anti-CD34 antibody", 
      "normal morphological pattern", 
      "glomerular development", 
      "one-kidney", 
      "autopsied fetuses", 
      "glomerular microvasculature", 
      "immunohistochemical parameters", 
      "immunohistochemical study", 
      "immunohistochemical markers", 
      "postnatal period", 
      "glomerular capsule", 
      "glomerular tuft", 
      "Bowman's capsule", 
      "superficial glomeruli", 
      "primitive nephrons", 
      "pathological alterations", 
      "interstitial vessels", 
      "human fetuses", 
      "periodic acid-methenamine silver stain", 
      "capillary tuft", 
      "fetuses", 
      "diagnostic precision", 
      "endothelial cells", 
      "positive significant correlation", 
      "significant correlation", 
      "silver stain", 
      "glomeruli", 
      "morphometrical analysis", 
      "antibodies", 
      "tuft diameter", 
      "capsule", 
      "morphological patterns", 
      "tufts", 
      "cells", 
      "autopsies", 
      "kidney", 
      "CD31", 
      "microvasculature", 
      "CD34", 
      "nephron", 
      "weeks", 
      "study", 
      "birth", 
      "total", 
      "same parameters", 
      "evaluation", 
      "organs", 
      "markers", 
      "alterations", 
      "stain", 
      "correlation", 
      "vessels", 
      "development", 
      "advances", 
      "autolysis", 
      "period", 
      "diameter", 
      "area", 
      "increase", 
      "patterns", 
      "data", 
      "primary structure", 
      "analysis", 
      "length", 
      "maturity", 
      "parameters", 
      "establishment", 
      "thickness", 
      "materials", 
      "variation", 
      "zone", 
      "zone thickness", 
      "precision", 
      "work", 
      "formula", 
      "structure", 
      "shape", 
      "gas", 
      "study one kidney", 
      "nephrogenic zone thickness", 
      "acid\u2013methenamine silver (PAMS) stain", 
      "capillary tuft diameter", 
      "intermediary glomeruli", 
      "advance of GA", 
      "mature glomeruli tuft", 
      "glomeruli tuft", 
      "renal interstitial vessels"
    ], 
    "name": "Histochemical and immunohistochemical study of the glomerular development in human fetuses", 
    "pagination": "257-262", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1034165342"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s00467-007-0654-4"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "17990004"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s00467-007-0654-4", 
      "https://app.dimensions.ai/details/publication/pub.1034165342"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2021-11-01T18:11", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20211101/entities/gbq_results/article/article_449.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1007/s00467-007-0654-4"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00467-007-0654-4'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00467-007-0654-4'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00467-007-0654-4'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00467-007-0654-4'


 

This table displays all metadata directly associated to this object as RDF triples.

256 TRIPLES      22 PREDICATES      130 URIs      119 LITERALS      18 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s00467-007-0654-4 schema:about N16f582b9533b4ad8acce6a3c9c6b2d69
2 N53cd0e4575a34d4888c7f00594a9423f
3 N56ce99db3e594456a14bdb1f2d012934
4 N583d78cb61694f2e9b96299e468174ca
5 N62a92b559a834868be009e2654f02ba1
6 N76cf487461cc48c8aa69a293182b4f7e
7 N7ae27ab4a97e4124ba05458139d77705
8 N8a41071e5d644cbfbaa10145847c8ff9
9 Nbf8656b1246247cd850a0672ba258e06
10 Nc11324436940490c838ff2d3772276af
11 Ndf81fc0b59fd4d3cabb33f5052ac091a
12 anzsrc-for:11
13 anzsrc-for:1103
14 schema:author N402b9fcb4f204069b65bfd2e7a564d2b
15 schema:citation sg:pub.10.1007/bf02898441
16 sg:pub.10.1007/s002040050165
17 sg:pub.10.1038/sj.jp.7211608
18 schema:datePublished 2007-11-08
19 schema:datePublishedReg 2007-11-08
20 schema:description Few studies exist that establish the normal morphological patterns of glomerular development, though this is one of the organs that continues to evolve morphologically during the postnatal period up to 4 weeks after birth. In our study one kidney from each autopsy of a total of 86 autopsies was analyzed [15 weeks to 40 weeks of gestational age (GA)]. We examined the variation in the nephrogenic zone thickness, the area and diameter of the glomerular tuft, the area and diameter of the glomerular capsule, and the immunohistochemical markers, anti-CD31 and anti-CD34 antibodies, which accompany the development of the glomerular microvasculature. Periodic acid–methenamine silver (PAMS) stain was used for the morphological and morphometrical analyses, and it was particularly useful in fetuses in which autolysis had occurred. The length of the nephrogenic zone (NZ) decreased with the increase of the GA (P < 0.001) according to the formula: \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${\text{GA}} = 36.5 - {\left( {0.05 \times {\text{length of NZ}}} \right)}$$\end{document}. The areas of the Bowman capsule (P < 0.0001), the capillary tuft (P < 0.0001), and the capillary tuft diameter (P = 0.00393) of the intermediary glomeruli increased with the advance of GA, with a positive significant correlation. The same parameters of the juxtamedullary and superficial glomeruli had no correlation with the advance of GA. The cells of the primary structures in the “S” shape of the primitive nephrons were negative for CD31 and CD34. Staining for both antibodies was found, for all GAs, in the endothelial cells of the mature glomeruli tuft and in the renal interstitial vessels. The data obtained in this work contribute to the evaluation of renal maturity in autopsied fetuses and are particularly important in fetuses when autolysis has occurred, to which the parameters used in this study can also be applied. The establishment of normal morphometric and immunohistochemical parameters for the evaluation of renal maturity increases the diagnostic precision of renal pathological alterations in aborted material and perinatal autopsy.
21 schema:genre article
22 schema:inLanguage en
23 schema:isAccessibleForFree false
24 schema:isPartOf N4a8f3e18b1c440fea4e58620aca27f21
25 Nb020fbb28e2a407ca4e4638f0f657246
26 sg:journal.1097267
27 schema:keywords Bowman's capsule
28 CD31
29 CD34
30 acid–methenamine silver (PAMS) stain
31 advance of GA
32 advances
33 alterations
34 analysis
35 anti-CD34 antibody
36 antibodies
37 area
38 autolysis
39 autopsied fetuses
40 autopsies
41 birth
42 capillary tuft
43 capillary tuft diameter
44 capsule
45 cells
46 correlation
47 data
48 development
49 diagnostic precision
50 diameter
51 endothelial cells
52 establishment
53 evaluation
54 fetuses
55 formula
56 gas
57 glomerular capsule
58 glomerular development
59 glomerular microvasculature
60 glomerular tuft
61 glomeruli
62 glomeruli tuft
63 human fetuses
64 immunohistochemical markers
65 immunohistochemical parameters
66 immunohistochemical study
67 increase
68 intermediary glomeruli
69 interstitial vessels
70 kidney
71 length
72 markers
73 materials
74 mature glomeruli tuft
75 maturity
76 microvasculature
77 morphological patterns
78 morphometrical analysis
79 nephrogenic zone
80 nephrogenic zone thickness
81 nephron
82 normal morphological pattern
83 one-kidney
84 organs
85 parameters
86 pathological alterations
87 patterns
88 period
89 periodic acid-methenamine silver stain
90 positive significant correlation
91 postnatal period
92 precision
93 primary structure
94 primitive nephrons
95 renal interstitial vessels
96 renal maturity
97 renal pathological alterations
98 same parameters
99 shape
100 significant correlation
101 silver stain
102 stain
103 structure
104 study
105 study one kidney
106 superficial glomeruli
107 thickness
108 total
109 tuft diameter
110 tufts
111 variation
112 vessels
113 weeks
114 work
115 zone
116 zone thickness
117 schema:name Histochemical and immunohistochemical study of the glomerular development in human fetuses
118 schema:pagination 257-262
119 schema:productId N9a6fc376515746ffa4b4706bbb62c900
120 Na6b88cf3fe734184bf2a5be6c5bf87f4
121 Ne6e07913400548a0a09ffd3a049634ca
122 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034165342
123 https://doi.org/10.1007/s00467-007-0654-4
124 schema:sdDatePublished 2021-11-01T18:11
125 schema:sdLicense https://scigraph.springernature.com/explorer/license/
126 schema:sdPublisher N538662f1c86c45809203fa677fc46df6
127 schema:url https://doi.org/10.1007/s00467-007-0654-4
128 sgo:license sg:explorer/license/
129 sgo:sdDataset articles
130 rdf:type schema:ScholarlyArticle
131 N16f582b9533b4ad8acce6a3c9c6b2d69 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
132 schema:name Humans
133 rdf:type schema:DefinedTerm
134 N338eb32e9b48432282140490d542a22f rdf:first sg:person.01035121507.51
135 rdf:rest N48c94fd5b6494036b1430726043e0abd
136 N402b9fcb4f204069b65bfd2e7a564d2b rdf:first Nb61a5ebef0354db6823f77e6b8a92702
137 rdf:rest N639cf3a100874c1d9e6685b750fd86dd
138 N48c94fd5b6494036b1430726043e0abd rdf:first sg:person.01224126024.60
139 rdf:rest N752dde1b958f42ffa12bee543dbfa82a
140 N4a8f3e18b1c440fea4e58620aca27f21 schema:volumeNumber 23
141 rdf:type schema:PublicationVolume
142 N538662f1c86c45809203fa677fc46df6 schema:name Springer Nature - SN SciGraph project
143 rdf:type schema:Organization
144 N53cd0e4575a34d4888c7f00594a9423f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
145 schema:name Gestational Age
146 rdf:type schema:DefinedTerm
147 N56ce99db3e594456a14bdb1f2d012934 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
148 schema:name Fetal Development
149 rdf:type schema:DefinedTerm
150 N583d78cb61694f2e9b96299e468174ca schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
151 schema:name Silver Staining
152 rdf:type schema:DefinedTerm
153 N62a92b559a834868be009e2654f02ba1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
154 schema:name Periodic Acid-Schiff Reaction
155 rdf:type schema:DefinedTerm
156 N639cf3a100874c1d9e6685b750fd86dd rdf:first sg:person.0773451024.09
157 rdf:rest N940fd26b984647d7ad5d5d7337957f2e
158 N752dde1b958f42ffa12bee543dbfa82a rdf:first sg:person.014127114354.44
159 rdf:rest Nfc5864d3c0f9474fa0972a091e2b32f7
160 N76cf487461cc48c8aa69a293182b4f7e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
161 schema:name Kidney Glomerulus
162 rdf:type schema:DefinedTerm
163 N7ae27ab4a97e4124ba05458139d77705 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
164 schema:name Kidney
165 rdf:type schema:DefinedTerm
166 N8a41071e5d644cbfbaa10145847c8ff9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
167 schema:name Retrospective Studies
168 rdf:type schema:DefinedTerm
169 N940fd26b984647d7ad5d5d7337957f2e rdf:first sg:person.01041564224.95
170 rdf:rest Nc6f5234076774cf7a35fdffe363e3a3e
171 N9a6fc376515746ffa4b4706bbb62c900 schema:name doi
172 schema:value 10.1007/s00467-007-0654-4
173 rdf:type schema:PropertyValue
174 Na6b88cf3fe734184bf2a5be6c5bf87f4 schema:name dimensions_id
175 schema:value pub.1034165342
176 rdf:type schema:PropertyValue
177 Nb020fbb28e2a407ca4e4638f0f657246 schema:issueNumber 2
178 rdf:type schema:PublicationIssue
179 Nb61a5ebef0354db6823f77e6b8a92702 schema:affiliation grid-institutes:grid.411281.f
180 schema:familyName Fonseca Ferraz
181 schema:givenName Mara Lúcia
182 rdf:type schema:Person
183 Nbf8656b1246247cd850a0672ba258e06 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
184 schema:name Biomarkers
185 rdf:type schema:DefinedTerm
186 Nc11324436940490c838ff2d3772276af schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
187 schema:name Fluorescent Antibody Technique, Indirect
188 rdf:type schema:DefinedTerm
189 Nc6f5234076774cf7a35fdffe363e3a3e rdf:first sg:person.01272273127.73
190 rdf:rest N338eb32e9b48432282140490d542a22f
191 Ndf81fc0b59fd4d3cabb33f5052ac091a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
192 schema:name Glycogen
193 rdf:type schema:DefinedTerm
194 Ne6e07913400548a0a09ffd3a049634ca schema:name pubmed_id
195 schema:value 17990004
196 rdf:type schema:PropertyValue
197 Nfc5864d3c0f9474fa0972a091e2b32f7 rdf:first sg:person.014255222026.69
198 rdf:rest rdf:nil
199 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
200 schema:name Medical and Health Sciences
201 rdf:type schema:DefinedTerm
202 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
203 schema:name Clinical Sciences
204 rdf:type schema:DefinedTerm
205 sg:journal.1097267 schema:issn 0931-041X
206 1432-198X
207 schema:name Pediatric Nephrology
208 schema:publisher Springer Nature
209 rdf:type schema:Periodical
210 sg:person.01035121507.51 schema:affiliation grid-institutes:grid.411281.f
211 schema:familyName Corrêa
212 schema:givenName Rosana Rosa Miranda
213 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01035121507.51
214 rdf:type schema:Person
215 sg:person.01041564224.95 schema:affiliation grid-institutes:grid.411281.f
216 schema:familyName Cavellani
217 schema:givenName Camila Lourencini
218 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01041564224.95
219 rdf:type schema:Person
220 sg:person.01224126024.60 schema:affiliation grid-institutes:grid.411281.f
221 schema:familyName dos Reis
222 schema:givenName Marlene Antônia
223 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01224126024.60
224 rdf:type schema:Person
225 sg:person.01272273127.73 schema:affiliation grid-institutes:grid.411281.f
226 schema:familyName Rossi
227 schema:givenName Renata Calciolari
228 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01272273127.73
229 rdf:type schema:Person
230 sg:person.014127114354.44 schema:affiliation grid-institutes:grid.411281.f
231 schema:familyName de Paula Antunes Teixeira
232 schema:givenName Vicente
233 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014127114354.44
234 rdf:type schema:Person
235 sg:person.014255222026.69 schema:affiliation grid-institutes:grid.411281.f
236 schema:familyName da Cunha Castro
237 schema:givenName Eumenia Costa
238 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014255222026.69
239 rdf:type schema:Person
240 sg:person.0773451024.09 schema:affiliation grid-institutes:grid.411281.f
241 schema:familyName dos Santos
242 schema:givenName Aline Mara
243 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0773451024.09
244 rdf:type schema:Person
245 sg:pub.10.1007/bf02898441 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038864066
246 https://doi.org/10.1007/bf02898441
247 rdf:type schema:CreativeWork
248 sg:pub.10.1007/s002040050165 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017889105
249 https://doi.org/10.1007/s002040050165
250 rdf:type schema:CreativeWork
251 sg:pub.10.1038/sj.jp.7211608 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002222470
252 https://doi.org/10.1038/sj.jp.7211608
253 rdf:type schema:CreativeWork
254 grid-institutes:grid.411281.f schema:alternateName Biological Sciences Department, General Pathology Discipline, Triângulo Mineiro Federal University, Rua Frei Paulino 30, Bairro Abadia. Cep 38025-180, Uberaba, Minas Gerais, Brazil
255 schema:name Biological Sciences Department, General Pathology Discipline, Triângulo Mineiro Federal University, Rua Frei Paulino 30, Bairro Abadia. Cep 38025-180, Uberaba, Minas Gerais, Brazil
256 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...