Pathomechanisms and the diagnosis of arterial hypertension in pediatric renal allograft recipients View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2004-11

AUTHORS

Rainer Büscher, Udo Vester, A.-M. Wingen, Peter F. Hoyer

ABSTRACT

Arterial hypertension is common in pediatric renal allograft recipients. While the causes are multifactorial, including chronic graft rejection, immunosuppressive therapy, and renal vascular disorders, the effect of hypertension on renal allograft function is detrimental. As in adults, if not treated early and aggressively, hypertension may lead to cardiovascular damage and graft failure. Pathophysiological changes in the arteries and kidney af-ter renal transplantation and the impact of receptor regulation have not been studied extensively in children. For identifying children with hypertension following renal transplantation casual blood pressure measurements do not accurately reflect average arterial blood pressure and circadian blood pressure rhythm. Ambulatory 24-h blood pressure monitoring should regularly be applied in trans-plant patients. The purpose of this review is to analyze pathophysiological aspects of risk factors for arterial hypertension and underline the importance of regular blood pressure monitoring and early therapeutic intervention. More... »

PAGES

1202-1211

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00467-004-1601-2

DOI

http://dx.doi.org/10.1007/s00467-004-1601-2

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1029556293

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/15365804


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