A boy with consecutive development of SLE and Wegener granulomatosis View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2004-01-23

AUTHORS

Özlem Erdoğan, Ayşe Őner, Gülay Demircin, Mehmet Bülbül, Leyla Memiş, Çiğdem Üner, Nural Kiper

ABSTRACT

An 11-year-old boy with consecutive development of systemic lupus erythematosus (SLE) and Wegener granulomatosis (WG) is presented. He was first admitted to the hospital with the findings of SLE, including crescentic glomerulonephritis, Coombs′ test-positive hemolytic anemia, hypocomplementemia, antinuclear antibody (ANA) positivity, and elevated levels of anti-double-stranded (ds) DNA antibodies. He was treated successfully with steroids, cyclophosphamide, and peritoneal dialysis. One month after his discharge he developed an apparent viral infection. Three weeks afterwards he was readmitted with the findings of lower respiratory tract involvement, maxillary sinusitis, nasal septum perforation, p- and c-antineutrophil cytoplasmic antibody (ANCA) positivity, but normal complement, ANA, and anti-ds DNA levels, suggesting the diagnosis of WG. He did not respond to anti-infectious and immunosuppressive treatment, and he died of Pseudomonas sepsis. More... »

PAGES

438-441

References to SciGraph publications

  • 2002-08-08. Clinical features in 17 paediatric patients with Wegener granulomatosis in PEDIATRIC NEPHROLOGY
  • 1993-08. Vasculitis in childhood in PEDIATRIC NEPHROLOGY
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s00467-003-1365-0

    DOI

    http://dx.doi.org/10.1007/s00467-003-1365-0

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1002308404

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/14740284


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