Long-term outcomes of endoscopic resection followed by additional surgery after non-curative resection in undifferentiated-type early gastric cancer: a nationwide multi-center ... View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2021-04-06

AUTHORS

Jie-Hyun Kim, Young-Il Kim, Ji Yong Ahn, Woon Geon Shin, Hyo-Joon Yang, Su Youn Nam, Byung-Hoon Min, Jae-Young Jang, Joo Hyun Lim, Wan Sik Lee, Bong Eun Lee, Moon Kyung Joo, Jae Myung Park, Hang Lak Lee, Tae-Geun Gweon, Moo In Park, Jeongmin Choi, Chung Hyun Tae, Young-Woo Kim, Boram Park, Il Ju Choi

ABSTRACT

BackgroundUndifferentiated-type early gastric cancer (UD EGC) shows lower curative resection rates after endoscopic submucosal dissection (ESD). Additional surgery is recommended after non-curative resection. We evaluated the long-term outcomes of ESD followed by additional surgery after non-curative resection in UD EGC compared to those for surgery as initial treatment.MethodsWe reviewed 1139 UD EGC patients who underwent ESD at 18 hospitals and 1956 patients who underwent surgery at two hospitals between February 2005 and May 2015. We enrolled 636 patients with non-curative ESD and 1429 surgery subjects beyond the curative ESD criteria. Among them, 133 patients with additional surgery after ESD (ESD + OP group) and 252 patients without additional surgery (ESD-only group) were matched 1:1 using propensity scores to patients with surgery as initial treatment (surgery group). Overall survival (OS) and recurrence-free survival (RFS) were compared.ResultsSignet ring cell carcinoma and poorly differentiated adenocarcinoma (PDA) were observed in 939 and 1126 cases, respectively. OS was significantly longer in the surgery group than in the ESD + OP group, especially for PDA. However, RFS was shorter in the ESD-only group than those in the ESD + OP and surgery groups. RFS did not differ significantly between the ESD + OP and surgery groups. Compared to the surgery group, the ESD-only and ESD + OP groups had an overall hazard ratio for RFS of 3.58 (95% confidence interval 1.44–8.88) and 0.46 (0.10–2.20), respectively.ConclusionsESD followed by additional surgery after non-curative resection showed comparable cancer-specific outcomes to initial surgery in UD EGC. More... »

PAGES

1847-1856

Journal

TITLE

Surgical Endoscopy

ISSUE

3

VOLUME

36

Author Affiliations

  • Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea
  • Center for Gastric Cancer, National Cancer Center, 323 Ilsan-ro, Ilsandong-gu, 10408, Goyang, Gyeonggi, South Korea
  • Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea
  • Department of Internal Medicine, Hallym University College of Medicine, Seoul, Korea
  • Department of Internal Medicine and Gastrointestinal Cancer Center, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea
  • Gastroenterology, Kyungpook National University Hospital, School of Medicine, Kyungpook National University, Daegu, Korea
  • Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
  • Department of Internal Medicine, College of Medicine, Kyung Hee University, Seoul, Korea
  • Department of Internal Medicine, Healthcare Research Institute, Healthcare System Gangnam Center, Seoul National University Hospital, Seoul, Korea
  • Department of Internal Medicine, Chonnam National University Medical School, Gwangju, Korea
  • Department of Internal Medicine, Pusan National University School of Medicine, Busan, Korea
  • Department of Internal Medicine, Korea University Guro Hospital, Korea University College of Medicine, Seoul, Korea
  • Department of Internal Medicine, Seoul St. Mary’s Hospital, The Catholic University of Korea, Seoul, Korea
  • Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea
  • Department of Internal Medicine, Incheon St. Mary’s Hospital, The Catholic University of Korea, College of Medicine, Incheon, Korea
  • Department of Internal Medicine, Kosin University College of Medicine, Busan, Korea
  • Department of Internal Medicine, Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Korea
  • Department of Internal Medicine, Ewha Womans University College of Medicine, Seoul, Korea
  • Biostatistics Collaboration Team, Research Core Center, Research Institute, National Cancer Center, Goyang, Korea
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s00464-021-08464-4

    DOI

    http://dx.doi.org/10.1007/s00464-021-08464-4

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1136956521

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/33825017


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Medical and Health Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1112", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Oncology and Carcinogenesis", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Carcinoma, Signet Ring Cell", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Endoscopic Mucosal Resection", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Gastric Mucosa", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Humans", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Retrospective Studies", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Stomach Neoplasms", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Treatment Outcome", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "affiliation": {
              "alternateName": "Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea", 
              "id": "http://www.grid.ac/institutes/grid.15444.30", 
              "name": [
                "Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Kim", 
            "givenName": "Jie-Hyun", 
            "id": "sg:person.014010425671.78", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014010425671.78"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Center for Gastric Cancer, National Cancer Center, 323 Ilsan-ro, Ilsandong-gu, 10408, Goyang, Gyeonggi, South Korea", 
              "id": "http://www.grid.ac/institutes/grid.410914.9", 
              "name": [
                "Center for Gastric Cancer, National Cancer Center, 323 Ilsan-ro, Ilsandong-gu, 10408, Goyang, Gyeonggi, South Korea"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Kim", 
            "givenName": "Young-Il", 
            "id": "sg:person.01077021270.28", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01077021270.28"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea", 
              "id": "http://www.grid.ac/institutes/grid.413967.e", 
              "name": [
                "Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Ahn", 
            "givenName": "Ji Yong", 
            "id": "sg:person.0625476022.66", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0625476022.66"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Internal Medicine, Hallym University College of Medicine, Seoul, Korea", 
              "id": "http://www.grid.ac/institutes/grid.256753.0", 
              "name": [
                "Department of Internal Medicine, Hallym University College of Medicine, Seoul, Korea"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Shin", 
            "givenName": "Woon Geon", 
            "id": "sg:person.01015043242.65", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01015043242.65"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Internal Medicine and Gastrointestinal Cancer Center, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea", 
              "id": "http://www.grid.ac/institutes/grid.415735.1", 
              "name": [
                "Department of Internal Medicine and Gastrointestinal Cancer Center, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Yang", 
            "givenName": "Hyo-Joon", 
            "id": "sg:person.0663162715.10", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0663162715.10"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Gastroenterology, Kyungpook National University Hospital, School of Medicine, Kyungpook National University, Daegu, Korea", 
              "id": "http://www.grid.ac/institutes/grid.411235.0", 
              "name": [
                "Gastroenterology, Kyungpook National University Hospital, School of Medicine, Kyungpook National University, Daegu, Korea"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Nam", 
            "givenName": "Su Youn", 
            "id": "sg:person.0734070654.02", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0734070654.02"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea", 
              "id": "http://www.grid.ac/institutes/grid.414964.a", 
              "name": [
                "Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Min", 
            "givenName": "Byung-Hoon", 
            "id": "sg:person.0735431177.39", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0735431177.39"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Internal Medicine, College of Medicine, Kyung Hee University, Seoul, Korea", 
              "id": "http://www.grid.ac/institutes/grid.289247.2", 
              "name": [
                "Department of Internal Medicine, College of Medicine, Kyung Hee University, Seoul, Korea"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Jang", 
            "givenName": "Jae-Young", 
            "id": "sg:person.011767610027.34", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011767610027.34"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Internal Medicine, Healthcare Research Institute, Healthcare System Gangnam Center, Seoul National University Hospital, Seoul, Korea", 
              "id": "http://www.grid.ac/institutes/grid.412484.f", 
              "name": [
                "Department of Internal Medicine, Healthcare Research Institute, Healthcare System Gangnam Center, Seoul National University Hospital, Seoul, Korea"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Lim", 
            "givenName": "Joo Hyun", 
            "id": "sg:person.01170270217.84", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01170270217.84"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Internal Medicine, Chonnam National University Medical School, Gwangju, Korea", 
              "id": "http://www.grid.ac/institutes/grid.14005.30", 
              "name": [
                "Department of Internal Medicine, Chonnam National University Medical School, Gwangju, Korea"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Lee", 
            "givenName": "Wan Sik", 
            "id": "sg:person.0675644341.18", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0675644341.18"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Internal Medicine, Pusan National University School of Medicine, Busan, Korea", 
              "id": "http://www.grid.ac/institutes/grid.262229.f", 
              "name": [
                "Department of Internal Medicine, Pusan National University School of Medicine, Busan, Korea"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Lee", 
            "givenName": "Bong Eun", 
            "id": "sg:person.0602112265.10", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0602112265.10"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Internal Medicine, Korea University Guro Hospital, Korea University College of Medicine, Seoul, Korea", 
              "id": "http://www.grid.ac/institutes/grid.222754.4", 
              "name": [
                "Department of Internal Medicine, Korea University Guro Hospital, Korea University College of Medicine, Seoul, Korea"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Joo", 
            "givenName": "Moon Kyung", 
            "id": "sg:person.01141371237.29", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01141371237.29"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Internal Medicine, Seoul St. Mary\u2019s Hospital, The Catholic University of Korea, Seoul, Korea", 
              "id": "http://www.grid.ac/institutes/grid.411947.e", 
              "name": [
                "Department of Internal Medicine, Seoul St. Mary\u2019s Hospital, The Catholic University of Korea, Seoul, Korea"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Park", 
            "givenName": "Jae Myung", 
            "id": "sg:person.0576362564.08", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0576362564.08"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea", 
              "id": "http://www.grid.ac/institutes/grid.49606.3d", 
              "name": [
                "Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Lee", 
            "givenName": "Hang Lak", 
            "id": "sg:person.01302057506.67", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01302057506.67"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Internal Medicine, Incheon St. Mary\u2019s Hospital, The Catholic University of Korea, College of Medicine, Incheon, Korea", 
              "id": "http://www.grid.ac/institutes/grid.464585.e", 
              "name": [
                "Department of Internal Medicine, Incheon St. Mary\u2019s Hospital, The Catholic University of Korea, College of Medicine, Incheon, Korea"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Gweon", 
            "givenName": "Tae-Geun", 
            "id": "sg:person.0740475105.05", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0740475105.05"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Internal Medicine, Kosin University College of Medicine, Busan, Korea", 
              "id": "http://www.grid.ac/institutes/grid.411144.5", 
              "name": [
                "Department of Internal Medicine, Kosin University College of Medicine, Busan, Korea"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Park", 
            "givenName": "Moo In", 
            "id": "sg:person.0737355231.42", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0737355231.42"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Internal Medicine, Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Korea", 
              "id": "http://www.grid.ac/institutes/grid.411627.7", 
              "name": [
                "Department of Internal Medicine, Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Korea"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Choi", 
            "givenName": "Jeongmin", 
            "id": "sg:person.01304516617.27", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01304516617.27"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Internal Medicine, Ewha Womans University College of Medicine, Seoul, Korea", 
              "id": "http://www.grid.ac/institutes/grid.255649.9", 
              "name": [
                "Department of Internal Medicine, Ewha Womans University College of Medicine, Seoul, Korea"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Tae", 
            "givenName": "Chung Hyun", 
            "id": "sg:person.01133340375.90", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01133340375.90"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Center for Gastric Cancer, National Cancer Center, 323 Ilsan-ro, Ilsandong-gu, 10408, Goyang, Gyeonggi, South Korea", 
              "id": "http://www.grid.ac/institutes/grid.410914.9", 
              "name": [
                "Center for Gastric Cancer, National Cancer Center, 323 Ilsan-ro, Ilsandong-gu, 10408, Goyang, Gyeonggi, South Korea"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Kim", 
            "givenName": "Young-Woo", 
            "id": "sg:person.015640317335.85", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015640317335.85"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Biostatistics Collaboration Team, Research Core Center, Research Institute, National Cancer Center, Goyang, Korea", 
              "id": "http://www.grid.ac/institutes/grid.410914.9", 
              "name": [
                "Biostatistics Collaboration Team, Research Core Center, Research Institute, National Cancer Center, Goyang, Korea"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Park", 
            "givenName": "Boram", 
            "id": "sg:person.0667061434.28", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0667061434.28"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Center for Gastric Cancer, National Cancer Center, 323 Ilsan-ro, Ilsandong-gu, 10408, Goyang, Gyeonggi, South Korea", 
              "id": "http://www.grid.ac/institutes/grid.410914.9", 
              "name": [
                "Center for Gastric Cancer, National Cancer Center, 323 Ilsan-ro, Ilsandong-gu, 10408, Goyang, Gyeonggi, South Korea"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Choi", 
            "givenName": "Il Ju", 
            "id": "sg:person.01123522666.07", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01123522666.07"
            ], 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "sg:pub.10.1245/s10434-017-6039-4", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1091133464", 
              "https://doi.org/10.1245/s10434-017-6039-4"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10120-020-01042-y", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1124870346", 
              "https://doi.org/10.1007/s10120-020-01042-y"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10120-016-0622-4", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1005167644", 
              "https://doi.org/10.1007/s10120-016-0622-4"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10120-015-0538-4", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1023951554", 
              "https://doi.org/10.1007/s10120-015-0538-4"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00464-017-5892-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1092274954", 
              "https://doi.org/10.1007/s00464-017-5892-3"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00464-014-3514-x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1044190428", 
              "https://doi.org/10.1007/s00464-014-3514-x"
            ], 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "2021-04-06", 
        "datePublishedReg": "2021-04-06", 
        "description": "BackgroundUndifferentiated-type early gastric cancer (UD EGC) shows lower curative resection rates after endoscopic submucosal dissection (ESD). Additional surgery is recommended after non-curative resection. We evaluated the long-term outcomes of ESD followed by additional surgery after non-curative resection in UD EGC compared to those for surgery as initial treatment.MethodsWe reviewed 1139 UD EGC patients who underwent ESD at 18 hospitals and 1956 patients who underwent surgery at two hospitals between February 2005 and May 2015. We enrolled 636 patients with non-curative ESD and 1429 surgery subjects beyond the curative ESD criteria. Among them, 133 patients with additional surgery after ESD (ESD\u2009+\u2009OP group) and 252 patients without additional surgery (ESD-only group) were matched 1:1 using propensity scores to patients with surgery as initial treatment (surgery group). Overall survival (OS) and recurrence-free survival (RFS) were compared.ResultsSignet ring cell carcinoma and poorly differentiated adenocarcinoma (PDA) were observed in 939 and 1126 cases, respectively. OS was significantly longer in the surgery group than in the ESD\u2009+\u2009OP group, especially for PDA. However, RFS was shorter in the ESD-only group than those in the ESD\u2009+\u2009OP and surgery groups. RFS did not differ significantly between the ESD\u2009+\u2009OP and surgery groups. Compared to the surgery group, the ESD-only and ESD\u2009+\u2009OP groups had an overall hazard ratio for RFS of 3.58 (95% confidence interval 1.44\u20138.88) and 0.46 (0.10\u20132.20), respectively.ConclusionsESD followed by additional surgery after non-curative resection showed comparable cancer-specific outcomes to initial surgery in UD EGC.", 
        "genre": "article", 
        "id": "sg:pub.10.1007/s00464-021-08464-4", 
        "isAccessibleForFree": false, 
        "isPartOf": [
          {
            "id": "sg:journal.1098220", 
            "issn": [
              "0930-2794", 
              "1432-2218"
            ], 
            "name": "Surgical Endoscopy", 
            "publisher": "Springer Nature", 
            "type": "Periodical"
          }, 
          {
            "issueNumber": "3", 
            "type": "PublicationIssue"
          }, 
          {
            "type": "PublicationVolume", 
            "volumeNumber": "36"
          }
        ], 
        "keywords": [
          "recurrence-free survival", 
          "non-curative resection", 
          "endoscopic submucosal dissection", 
          "additional surgery", 
          "long-term outcomes", 
          "early gastric cancer", 
          "surgery group", 
          "overall survival", 
          "initial treatment", 
          "OP group", 
          "gastric cancer", 
          "UD-EGC", 
          "non-curative endoscopic submucosal dissection", 
          "undifferentiated-type early gastric cancer", 
          "nationwide multi-center study", 
          "curative resection rate", 
          "overall hazard ratio", 
          "cancer-specific outcomes", 
          "multi-center study", 
          "ESD criteria", 
          "resection rate", 
          "initial surgery", 
          "hazard ratio", 
          "endoscopic resection", 
          "EGC patients", 
          "cell carcinoma", 
          "submucosal dissection", 
          "resection", 
          "surgery", 
          "patients", 
          "surgery subjects", 
          "propensity score", 
          "hospital", 
          "outcomes", 
          "cancer", 
          "survival", 
          "treatment", 
          "group", 
          "ConclusionsESD", 
          "adenocarcinoma", 
          "carcinoma", 
          "MethodsWe", 
          "dissection", 
          "scores", 
          "EGC", 
          "OP", 
          "subjects", 
          "criteria", 
          "cases", 
          "study", 
          "rate", 
          "ratio", 
          "PDA"
        ], 
        "name": "Long-term outcomes of endoscopic resection followed by additional surgery after non-curative resection in undifferentiated-type early gastric cancer: a nationwide multi-center study", 
        "pagination": "1847-1856", 
        "productId": [
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1136956521"
            ]
          }, 
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1007/s00464-021-08464-4"
            ]
          }, 
          {
            "name": "pubmed_id", 
            "type": "PropertyValue", 
            "value": [
              "33825017"
            ]
          }
        ], 
        "sameAs": [
          "https://doi.org/10.1007/s00464-021-08464-4", 
          "https://app.dimensions.ai/details/publication/pub.1136956521"
        ], 
        "sdDataset": "articles", 
        "sdDatePublished": "2022-10-01T06:49", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-springernature-scigraph/baseset/20221001/entities/gbq_results/article/article_899.jsonl", 
        "type": "ScholarlyArticle", 
        "url": "https://doi.org/10.1007/s00464-021-08464-4"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00464-021-08464-4'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00464-021-08464-4'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00464-021-08464-4'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00464-021-08464-4'


     

    This table displays all metadata directly associated to this object as RDF triples.

    359 TRIPLES      21 PREDICATES      91 URIs      77 LITERALS      14 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1007/s00464-021-08464-4 schema:about N067324c9a8ea4d85a582f175dbdff5e7
    2 N33801892ec284caa8acd1a39c17cd076
    3 N56e6c06d80f646e2ac63839534812991
    4 N7dc56c735c164366a6c456d1f3b34b27
    5 Nbe9a63eae86f4bd1b9d9408c15bf4c15
    6 Ncc893d3828a8423e84dc30698204cff1
    7 Ned7b7ef35751462290a98ae763567dad
    8 anzsrc-for:11
    9 anzsrc-for:1112
    10 schema:author Nfaa8a6dcaacd499897e42f8fd189c0fa
    11 schema:citation sg:pub.10.1007/s00464-014-3514-x
    12 sg:pub.10.1007/s00464-017-5892-3
    13 sg:pub.10.1007/s10120-015-0538-4
    14 sg:pub.10.1007/s10120-016-0622-4
    15 sg:pub.10.1007/s10120-020-01042-y
    16 sg:pub.10.1245/s10434-017-6039-4
    17 schema:datePublished 2021-04-06
    18 schema:datePublishedReg 2021-04-06
    19 schema:description BackgroundUndifferentiated-type early gastric cancer (UD EGC) shows lower curative resection rates after endoscopic submucosal dissection (ESD). Additional surgery is recommended after non-curative resection. We evaluated the long-term outcomes of ESD followed by additional surgery after non-curative resection in UD EGC compared to those for surgery as initial treatment.MethodsWe reviewed 1139 UD EGC patients who underwent ESD at 18 hospitals and 1956 patients who underwent surgery at two hospitals between February 2005 and May 2015. We enrolled 636 patients with non-curative ESD and 1429 surgery subjects beyond the curative ESD criteria. Among them, 133 patients with additional surgery after ESD (ESD + OP group) and 252 patients without additional surgery (ESD-only group) were matched 1:1 using propensity scores to patients with surgery as initial treatment (surgery group). Overall survival (OS) and recurrence-free survival (RFS) were compared.ResultsSignet ring cell carcinoma and poorly differentiated adenocarcinoma (PDA) were observed in 939 and 1126 cases, respectively. OS was significantly longer in the surgery group than in the ESD + OP group, especially for PDA. However, RFS was shorter in the ESD-only group than those in the ESD + OP and surgery groups. RFS did not differ significantly between the ESD + OP and surgery groups. Compared to the surgery group, the ESD-only and ESD + OP groups had an overall hazard ratio for RFS of 3.58 (95% confidence interval 1.44–8.88) and 0.46 (0.10–2.20), respectively.ConclusionsESD followed by additional surgery after non-curative resection showed comparable cancer-specific outcomes to initial surgery in UD EGC.
    20 schema:genre article
    21 schema:isAccessibleForFree false
    22 schema:isPartOf N40505044762b46a98f407dff10cc74dc
    23 Nf136b4bebc73410ebd9c559b987f2553
    24 sg:journal.1098220
    25 schema:keywords ConclusionsESD
    26 EGC
    27 EGC patients
    28 ESD criteria
    29 MethodsWe
    30 OP
    31 OP group
    32 PDA
    33 UD-EGC
    34 additional surgery
    35 adenocarcinoma
    36 cancer
    37 cancer-specific outcomes
    38 carcinoma
    39 cases
    40 cell carcinoma
    41 criteria
    42 curative resection rate
    43 dissection
    44 early gastric cancer
    45 endoscopic resection
    46 endoscopic submucosal dissection
    47 gastric cancer
    48 group
    49 hazard ratio
    50 hospital
    51 initial surgery
    52 initial treatment
    53 long-term outcomes
    54 multi-center study
    55 nationwide multi-center study
    56 non-curative endoscopic submucosal dissection
    57 non-curative resection
    58 outcomes
    59 overall hazard ratio
    60 overall survival
    61 patients
    62 propensity score
    63 rate
    64 ratio
    65 recurrence-free survival
    66 resection
    67 resection rate
    68 scores
    69 study
    70 subjects
    71 submucosal dissection
    72 surgery
    73 surgery group
    74 surgery subjects
    75 survival
    76 treatment
    77 undifferentiated-type early gastric cancer
    78 schema:name Long-term outcomes of endoscopic resection followed by additional surgery after non-curative resection in undifferentiated-type early gastric cancer: a nationwide multi-center study
    79 schema:pagination 1847-1856
    80 schema:productId N00c46c3a241d43bfa6fc271eb346ba61
    81 N624f84d327ca4e4f936d2cd33042865d
    82 N6cb9e918b747470884dba3f805154fb0
    83 schema:sameAs https://app.dimensions.ai/details/publication/pub.1136956521
    84 https://doi.org/10.1007/s00464-021-08464-4
    85 schema:sdDatePublished 2022-10-01T06:49
    86 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    87 schema:sdPublisher N342810ddc7f144429a796c48d3d43da1
    88 schema:url https://doi.org/10.1007/s00464-021-08464-4
    89 sgo:license sg:explorer/license/
    90 sgo:sdDataset articles
    91 rdf:type schema:ScholarlyArticle
    92 N00c46c3a241d43bfa6fc271eb346ba61 schema:name dimensions_id
    93 schema:value pub.1136956521
    94 rdf:type schema:PropertyValue
    95 N0139012adc3644eb9e567c24f7ea2455 rdf:first sg:person.01302057506.67
    96 rdf:rest N12eddd799673415189d3b47d90fcf50d
    97 N067324c9a8ea4d85a582f175dbdff5e7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    98 schema:name Carcinoma, Signet Ring Cell
    99 rdf:type schema:DefinedTerm
    100 N12eddd799673415189d3b47d90fcf50d rdf:first sg:person.0740475105.05
    101 rdf:rest N2ce643b25b9e4a408829f83d6c53c4b5
    102 N28ef0cca330e4c98bb13f8391e1a18ad rdf:first sg:person.01133340375.90
    103 rdf:rest N794e07a2fbf24f469cb14560c07fbb56
    104 N2ce643b25b9e4a408829f83d6c53c4b5 rdf:first sg:person.0737355231.42
    105 rdf:rest Na6b002b125c742889e56d14e92babc2e
    106 N32ed6e0ca7744ad4b8ffec9f87d34f3b rdf:first sg:person.0602112265.10
    107 rdf:rest N3c9dd28db9e540ddb1e4061cc56d5a6a
    108 N33801892ec284caa8acd1a39c17cd076 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    109 schema:name Gastric Mucosa
    110 rdf:type schema:DefinedTerm
    111 N342810ddc7f144429a796c48d3d43da1 schema:name Springer Nature - SN SciGraph project
    112 rdf:type schema:Organization
    113 N3c9dd28db9e540ddb1e4061cc56d5a6a rdf:first sg:person.01141371237.29
    114 rdf:rest Nd1ed2861df26445c97bcec59d5be7325
    115 N40505044762b46a98f407dff10cc74dc schema:issueNumber 3
    116 rdf:type schema:PublicationIssue
    117 N431a4356bf2f4c55b71383062e347281 rdf:first sg:person.01015043242.65
    118 rdf:rest N738ee34432af4c1980d5f2086b2e13b8
    119 N4902d5d9a11a4b3996a12a820be51b97 rdf:first sg:person.0735431177.39
    120 rdf:rest N8b0b4008eaab404b985d97d1f6b5ddc6
    121 N56e6c06d80f646e2ac63839534812991 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    122 schema:name Retrospective Studies
    123 rdf:type schema:DefinedTerm
    124 N624f84d327ca4e4f936d2cd33042865d schema:name pubmed_id
    125 schema:value 33825017
    126 rdf:type schema:PropertyValue
    127 N6cb9e918b747470884dba3f805154fb0 schema:name doi
    128 schema:value 10.1007/s00464-021-08464-4
    129 rdf:type schema:PropertyValue
    130 N738ee34432af4c1980d5f2086b2e13b8 rdf:first sg:person.0663162715.10
    131 rdf:rest N7432c6fd91f446248b981c4365174c46
    132 N7432c6fd91f446248b981c4365174c46 rdf:first sg:person.0734070654.02
    133 rdf:rest N4902d5d9a11a4b3996a12a820be51b97
    134 N794e07a2fbf24f469cb14560c07fbb56 rdf:first sg:person.015640317335.85
    135 rdf:rest Nae0d42619eec45c0aeded545a77206d7
    136 N7dc56c735c164366a6c456d1f3b34b27 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    137 schema:name Humans
    138 rdf:type schema:DefinedTerm
    139 N86282f5a78874410ad8fd9e1c427b515 rdf:first sg:person.01077021270.28
    140 rdf:rest Nd18d37cced054e3b8c19ac40d793fc55
    141 N8b0b4008eaab404b985d97d1f6b5ddc6 rdf:first sg:person.011767610027.34
    142 rdf:rest N9d9c332c858349b1ba2707a370b9013c
    143 N9cf265f11b8f4b65860bd8127a05cf8f rdf:first sg:person.01123522666.07
    144 rdf:rest rdf:nil
    145 N9d9c332c858349b1ba2707a370b9013c rdf:first sg:person.01170270217.84
    146 rdf:rest Nab5c14d88ec144eba105e8f7eb97976e
    147 Na6b002b125c742889e56d14e92babc2e rdf:first sg:person.01304516617.27
    148 rdf:rest N28ef0cca330e4c98bb13f8391e1a18ad
    149 Nab5c14d88ec144eba105e8f7eb97976e rdf:first sg:person.0675644341.18
    150 rdf:rest N32ed6e0ca7744ad4b8ffec9f87d34f3b
    151 Nae0d42619eec45c0aeded545a77206d7 rdf:first sg:person.0667061434.28
    152 rdf:rest N9cf265f11b8f4b65860bd8127a05cf8f
    153 Nbe9a63eae86f4bd1b9d9408c15bf4c15 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    154 schema:name Treatment Outcome
    155 rdf:type schema:DefinedTerm
    156 Ncc893d3828a8423e84dc30698204cff1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    157 schema:name Endoscopic Mucosal Resection
    158 rdf:type schema:DefinedTerm
    159 Nd18d37cced054e3b8c19ac40d793fc55 rdf:first sg:person.0625476022.66
    160 rdf:rest N431a4356bf2f4c55b71383062e347281
    161 Nd1ed2861df26445c97bcec59d5be7325 rdf:first sg:person.0576362564.08
    162 rdf:rest N0139012adc3644eb9e567c24f7ea2455
    163 Ned7b7ef35751462290a98ae763567dad schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    164 schema:name Stomach Neoplasms
    165 rdf:type schema:DefinedTerm
    166 Nf136b4bebc73410ebd9c559b987f2553 schema:volumeNumber 36
    167 rdf:type schema:PublicationVolume
    168 Nfaa8a6dcaacd499897e42f8fd189c0fa rdf:first sg:person.014010425671.78
    169 rdf:rest N86282f5a78874410ad8fd9e1c427b515
    170 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
    171 schema:name Medical and Health Sciences
    172 rdf:type schema:DefinedTerm
    173 anzsrc-for:1112 schema:inDefinedTermSet anzsrc-for:
    174 schema:name Oncology and Carcinogenesis
    175 rdf:type schema:DefinedTerm
    176 sg:journal.1098220 schema:issn 0930-2794
    177 1432-2218
    178 schema:name Surgical Endoscopy
    179 schema:publisher Springer Nature
    180 rdf:type schema:Periodical
    181 sg:person.01015043242.65 schema:affiliation grid-institutes:grid.256753.0
    182 schema:familyName Shin
    183 schema:givenName Woon Geon
    184 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01015043242.65
    185 rdf:type schema:Person
    186 sg:person.01077021270.28 schema:affiliation grid-institutes:grid.410914.9
    187 schema:familyName Kim
    188 schema:givenName Young-Il
    189 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01077021270.28
    190 rdf:type schema:Person
    191 sg:person.01123522666.07 schema:affiliation grid-institutes:grid.410914.9
    192 schema:familyName Choi
    193 schema:givenName Il Ju
    194 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01123522666.07
    195 rdf:type schema:Person
    196 sg:person.01133340375.90 schema:affiliation grid-institutes:grid.255649.9
    197 schema:familyName Tae
    198 schema:givenName Chung Hyun
    199 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01133340375.90
    200 rdf:type schema:Person
    201 sg:person.01141371237.29 schema:affiliation grid-institutes:grid.222754.4
    202 schema:familyName Joo
    203 schema:givenName Moon Kyung
    204 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01141371237.29
    205 rdf:type schema:Person
    206 sg:person.01170270217.84 schema:affiliation grid-institutes:grid.412484.f
    207 schema:familyName Lim
    208 schema:givenName Joo Hyun
    209 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01170270217.84
    210 rdf:type schema:Person
    211 sg:person.011767610027.34 schema:affiliation grid-institutes:grid.289247.2
    212 schema:familyName Jang
    213 schema:givenName Jae-Young
    214 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011767610027.34
    215 rdf:type schema:Person
    216 sg:person.01302057506.67 schema:affiliation grid-institutes:grid.49606.3d
    217 schema:familyName Lee
    218 schema:givenName Hang Lak
    219 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01302057506.67
    220 rdf:type schema:Person
    221 sg:person.01304516617.27 schema:affiliation grid-institutes:grid.411627.7
    222 schema:familyName Choi
    223 schema:givenName Jeongmin
    224 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01304516617.27
    225 rdf:type schema:Person
    226 sg:person.014010425671.78 schema:affiliation grid-institutes:grid.15444.30
    227 schema:familyName Kim
    228 schema:givenName Jie-Hyun
    229 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014010425671.78
    230 rdf:type schema:Person
    231 sg:person.015640317335.85 schema:affiliation grid-institutes:grid.410914.9
    232 schema:familyName Kim
    233 schema:givenName Young-Woo
    234 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015640317335.85
    235 rdf:type schema:Person
    236 sg:person.0576362564.08 schema:affiliation grid-institutes:grid.411947.e
    237 schema:familyName Park
    238 schema:givenName Jae Myung
    239 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0576362564.08
    240 rdf:type schema:Person
    241 sg:person.0602112265.10 schema:affiliation grid-institutes:grid.262229.f
    242 schema:familyName Lee
    243 schema:givenName Bong Eun
    244 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0602112265.10
    245 rdf:type schema:Person
    246 sg:person.0625476022.66 schema:affiliation grid-institutes:grid.413967.e
    247 schema:familyName Ahn
    248 schema:givenName Ji Yong
    249 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0625476022.66
    250 rdf:type schema:Person
    251 sg:person.0663162715.10 schema:affiliation grid-institutes:grid.415735.1
    252 schema:familyName Yang
    253 schema:givenName Hyo-Joon
    254 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0663162715.10
    255 rdf:type schema:Person
    256 sg:person.0667061434.28 schema:affiliation grid-institutes:grid.410914.9
    257 schema:familyName Park
    258 schema:givenName Boram
    259 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0667061434.28
    260 rdf:type schema:Person
    261 sg:person.0675644341.18 schema:affiliation grid-institutes:grid.14005.30
    262 schema:familyName Lee
    263 schema:givenName Wan Sik
    264 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0675644341.18
    265 rdf:type schema:Person
    266 sg:person.0734070654.02 schema:affiliation grid-institutes:grid.411235.0
    267 schema:familyName Nam
    268 schema:givenName Su Youn
    269 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0734070654.02
    270 rdf:type schema:Person
    271 sg:person.0735431177.39 schema:affiliation grid-institutes:grid.414964.a
    272 schema:familyName Min
    273 schema:givenName Byung-Hoon
    274 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0735431177.39
    275 rdf:type schema:Person
    276 sg:person.0737355231.42 schema:affiliation grid-institutes:grid.411144.5
    277 schema:familyName Park
    278 schema:givenName Moo In
    279 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0737355231.42
    280 rdf:type schema:Person
    281 sg:person.0740475105.05 schema:affiliation grid-institutes:grid.464585.e
    282 schema:familyName Gweon
    283 schema:givenName Tae-Geun
    284 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0740475105.05
    285 rdf:type schema:Person
    286 sg:pub.10.1007/s00464-014-3514-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1044190428
    287 https://doi.org/10.1007/s00464-014-3514-x
    288 rdf:type schema:CreativeWork
    289 sg:pub.10.1007/s00464-017-5892-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1092274954
    290 https://doi.org/10.1007/s00464-017-5892-3
    291 rdf:type schema:CreativeWork
    292 sg:pub.10.1007/s10120-015-0538-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023951554
    293 https://doi.org/10.1007/s10120-015-0538-4
    294 rdf:type schema:CreativeWork
    295 sg:pub.10.1007/s10120-016-0622-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005167644
    296 https://doi.org/10.1007/s10120-016-0622-4
    297 rdf:type schema:CreativeWork
    298 sg:pub.10.1007/s10120-020-01042-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1124870346
    299 https://doi.org/10.1007/s10120-020-01042-y
    300 rdf:type schema:CreativeWork
    301 sg:pub.10.1245/s10434-017-6039-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1091133464
    302 https://doi.org/10.1245/s10434-017-6039-4
    303 rdf:type schema:CreativeWork
    304 grid-institutes:grid.14005.30 schema:alternateName Department of Internal Medicine, Chonnam National University Medical School, Gwangju, Korea
    305 schema:name Department of Internal Medicine, Chonnam National University Medical School, Gwangju, Korea
    306 rdf:type schema:Organization
    307 grid-institutes:grid.15444.30 schema:alternateName Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea
    308 schema:name Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea
    309 rdf:type schema:Organization
    310 grid-institutes:grid.222754.4 schema:alternateName Department of Internal Medicine, Korea University Guro Hospital, Korea University College of Medicine, Seoul, Korea
    311 schema:name Department of Internal Medicine, Korea University Guro Hospital, Korea University College of Medicine, Seoul, Korea
    312 rdf:type schema:Organization
    313 grid-institutes:grid.255649.9 schema:alternateName Department of Internal Medicine, Ewha Womans University College of Medicine, Seoul, Korea
    314 schema:name Department of Internal Medicine, Ewha Womans University College of Medicine, Seoul, Korea
    315 rdf:type schema:Organization
    316 grid-institutes:grid.256753.0 schema:alternateName Department of Internal Medicine, Hallym University College of Medicine, Seoul, Korea
    317 schema:name Department of Internal Medicine, Hallym University College of Medicine, Seoul, Korea
    318 rdf:type schema:Organization
    319 grid-institutes:grid.262229.f schema:alternateName Department of Internal Medicine, Pusan National University School of Medicine, Busan, Korea
    320 schema:name Department of Internal Medicine, Pusan National University School of Medicine, Busan, Korea
    321 rdf:type schema:Organization
    322 grid-institutes:grid.289247.2 schema:alternateName Department of Internal Medicine, College of Medicine, Kyung Hee University, Seoul, Korea
    323 schema:name Department of Internal Medicine, College of Medicine, Kyung Hee University, Seoul, Korea
    324 rdf:type schema:Organization
    325 grid-institutes:grid.410914.9 schema:alternateName Biostatistics Collaboration Team, Research Core Center, Research Institute, National Cancer Center, Goyang, Korea
    326 Center for Gastric Cancer, National Cancer Center, 323 Ilsan-ro, Ilsandong-gu, 10408, Goyang, Gyeonggi, South Korea
    327 schema:name Biostatistics Collaboration Team, Research Core Center, Research Institute, National Cancer Center, Goyang, Korea
    328 Center for Gastric Cancer, National Cancer Center, 323 Ilsan-ro, Ilsandong-gu, 10408, Goyang, Gyeonggi, South Korea
    329 rdf:type schema:Organization
    330 grid-institutes:grid.411144.5 schema:alternateName Department of Internal Medicine, Kosin University College of Medicine, Busan, Korea
    331 schema:name Department of Internal Medicine, Kosin University College of Medicine, Busan, Korea
    332 rdf:type schema:Organization
    333 grid-institutes:grid.411235.0 schema:alternateName Gastroenterology, Kyungpook National University Hospital, School of Medicine, Kyungpook National University, Daegu, Korea
    334 schema:name Gastroenterology, Kyungpook National University Hospital, School of Medicine, Kyungpook National University, Daegu, Korea
    335 rdf:type schema:Organization
    336 grid-institutes:grid.411627.7 schema:alternateName Department of Internal Medicine, Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Korea
    337 schema:name Department of Internal Medicine, Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Korea
    338 rdf:type schema:Organization
    339 grid-institutes:grid.411947.e schema:alternateName Department of Internal Medicine, Seoul St. Mary’s Hospital, The Catholic University of Korea, Seoul, Korea
    340 schema:name Department of Internal Medicine, Seoul St. Mary’s Hospital, The Catholic University of Korea, Seoul, Korea
    341 rdf:type schema:Organization
    342 grid-institutes:grid.412484.f schema:alternateName Department of Internal Medicine, Healthcare Research Institute, Healthcare System Gangnam Center, Seoul National University Hospital, Seoul, Korea
    343 schema:name Department of Internal Medicine, Healthcare Research Institute, Healthcare System Gangnam Center, Seoul National University Hospital, Seoul, Korea
    344 rdf:type schema:Organization
    345 grid-institutes:grid.413967.e schema:alternateName Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea
    346 schema:name Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea
    347 rdf:type schema:Organization
    348 grid-institutes:grid.414964.a schema:alternateName Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    349 schema:name Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    350 rdf:type schema:Organization
    351 grid-institutes:grid.415735.1 schema:alternateName Department of Internal Medicine and Gastrointestinal Cancer Center, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea
    352 schema:name Department of Internal Medicine and Gastrointestinal Cancer Center, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea
    353 rdf:type schema:Organization
    354 grid-institutes:grid.464585.e schema:alternateName Department of Internal Medicine, Incheon St. Mary’s Hospital, The Catholic University of Korea, College of Medicine, Incheon, Korea
    355 schema:name Department of Internal Medicine, Incheon St. Mary’s Hospital, The Catholic University of Korea, College of Medicine, Incheon, Korea
    356 rdf:type schema:Organization
    357 grid-institutes:grid.49606.3d schema:alternateName Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea
    358 schema:name Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea
    359 rdf:type schema:Organization
     




    Preview window. Press ESC to close (or click here)


    ...