Ontology type: schema:ScholarlyArticle
2017-12-06
AUTHORSDae Hwan Kang, Cheol Woong Choi, Hyung Wook Kim, Su Bum Park, Su Jin Kim, Hyeong Seok Nam, Dae Gon Ryu
ABSTRACTBackgroundThe optimal management of precursor lesions such as gastric low-grade dysplasia is crucial in order to improve gastric cancer-related mortality. However, there are no universally accepted management guidelines regarding which lesions should be resected or should be monitored by follow-up visits.Patients and methodsWe retrospectively analyzed data from 1006 gastric low-grade dysplasia lesions that had been resected via endoscopic submucosal dissection. We also evaluated the endoscopic risk factors associated with upstage diagnosis from low-grade dysplasia to high-grade dysplasia or gastric cancer.ResultsThe mean age of our patients was 63.7 ± 9.1 years and 70.3% of our study population included men. The predominant location and gross type of lesions was the lower third of the stomach (78.6%) and the elevated type (57.8%), respectively. The rates of pathological concordance, upstage, and downstage diagnosis were 85.3, 12.1, and 2.6%, respectively. Multivariate analysis, after adjusting for age and sex, showed that a lesion size ≥ 10 mm (Odds ratio [OR] 2.231; p = 0.003), erythema (OR 7.315; p < 0.001), nodularity (OR 5.589; p < 0.001), depression (OR 3.024; p = 0.002), and erosion (OR 7.680; p < 0.001) were all factors significantly associated with upstage diagnosis. Furthermore, an increasing number of risk factors was associated with an increasing frequency of upstage diagnosis; if there were no risk factors, then there was no upstage diagnosis.ConclusionsThis study identified several risk factors that were significantly associated with the upstage diagnosis of gastric low-grade dysplasia: lesion size ≥ 10 mm and a variety of surface changes (erythema, nodularity, depression, and erosion). Our data indicate that if there is no evidence of these endoscopic risk factors, then regular follow-up may be considered, according to the patient’s combined comorbid conditions. More... »
PAGES2732-2738
http://scigraph.springernature.com/pub.10.1007/s00464-017-5971-5
DOIhttp://dx.doi.org/10.1007/s00464-017-5971-5
DIMENSIONShttps://app.dimensions.ai/details/publication/pub.1099694716
PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/29214514
JSON-LD is the canonical representation for SciGraph data.
TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT
[
{
"@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json",
"about": [
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Medical and Health Sciences",
"type": "DefinedTerm"
},
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1117",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Public Health and Health Services",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Biopsy",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Carcinoma in Situ",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Endoscopic Mucosal Resection",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Female",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Gastric Mucosa",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Gastroscopy",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Humans",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Male",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Middle Aged",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Neoplasm Staging",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Odds Ratio",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Retrospective Studies",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Risk Factors",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Stomach Neoplasms",
"type": "DefinedTerm"
}
],
"author": [
{
"affiliation": {
"alternateName": "Department of Internal Medicine, Pusan National University School of Medicine and Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan, South Korea",
"id": "http://www.grid.ac/institutes/grid.412591.a",
"name": [
"Department of Internal Medicine, Pusan National University School of Medicine and Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan, South Korea"
],
"type": "Organization"
},
"familyName": "Kang",
"givenName": "Dae Hwan",
"id": "sg:person.01217676577.29",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01217676577.29"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Department of Internal Medicine, Medical Research Institute, Pusan National University School of Medicine and Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, 20, Geumo-ro, Mulgeum-eup, Yangsan-si, Gyeongsangnam-do, 50612, Yangsan, South Korea",
"id": "http://www.grid.ac/institutes/grid.412591.a",
"name": [
"Department of Internal Medicine, Pusan National University School of Medicine and Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan, South Korea",
"Department of Internal Medicine, Medical Research Institute, Pusan National University School of Medicine and Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, 20, Geumo-ro, Mulgeum-eup, Yangsan-si, Gyeongsangnam-do, 50612, Yangsan, South Korea"
],
"type": "Organization"
},
"familyName": "Choi",
"givenName": "Cheol Woong",
"id": "sg:person.0731760511.13",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0731760511.13"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Department of Internal Medicine, Pusan National University School of Medicine and Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan, South Korea",
"id": "http://www.grid.ac/institutes/grid.412591.a",
"name": [
"Department of Internal Medicine, Pusan National University School of Medicine and Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan, South Korea"
],
"type": "Organization"
},
"familyName": "Kim",
"givenName": "Hyung Wook",
"id": "sg:person.01046207111.77",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01046207111.77"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Department of Internal Medicine, Pusan National University School of Medicine and Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan, South Korea",
"id": "http://www.grid.ac/institutes/grid.412591.a",
"name": [
"Department of Internal Medicine, Pusan National University School of Medicine and Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan, South Korea"
],
"type": "Organization"
},
"familyName": "Park",
"givenName": "Su Bum",
"id": "sg:person.01022177256.90",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01022177256.90"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Department of Internal Medicine, Pusan National University School of Medicine and Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan, South Korea",
"id": "http://www.grid.ac/institutes/grid.412591.a",
"name": [
"Department of Internal Medicine, Pusan National University School of Medicine and Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan, South Korea"
],
"type": "Organization"
},
"familyName": "Kim",
"givenName": "Su Jin",
"id": "sg:person.01341524512.60",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01341524512.60"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Department of Internal Medicine, Pusan National University School of Medicine and Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan, South Korea",
"id": "http://www.grid.ac/institutes/grid.412591.a",
"name": [
"Department of Internal Medicine, Pusan National University School of Medicine and Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan, South Korea"
],
"type": "Organization"
},
"familyName": "Nam",
"givenName": "Hyeong Seok",
"id": "sg:person.01036062671.42",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01036062671.42"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Department of Internal Medicine, Pusan National University School of Medicine and Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan, South Korea",
"id": "http://www.grid.ac/institutes/grid.412591.a",
"name": [
"Department of Internal Medicine, Pusan National University School of Medicine and Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan, South Korea"
],
"type": "Organization"
},
"familyName": "Ryu",
"givenName": "Dae Gon",
"id": "sg:person.01071176670.17",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01071176670.17"
],
"type": "Person"
}
],
"citation": [
{
"id": "sg:pub.10.1007/s00464-015-4248-0",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1043030572",
"https://doi.org/10.1007/s00464-015-4248-0"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s10620-013-2874-8",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1038578415",
"https://doi.org/10.1007/s10620-013-2874-8"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/ajg.2016.188",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1031706697",
"https://doi.org/10.1038/ajg.2016.188"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s10120-011-0041-5",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1016436945",
"https://doi.org/10.1007/s10120-011-0041-5"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s00464-016-5086-4",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1017274841",
"https://doi.org/10.1007/s00464-016-5086-4"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s10620-013-2805-8",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1025456843",
"https://doi.org/10.1007/s10620-013-2805-8"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s00464-014-3457-2",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1026811320",
"https://doi.org/10.1007/s00464-014-3457-2"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s00535-010-0289-2",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1032761200",
"https://doi.org/10.1007/s00535-010-0289-2"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s10120-013-0322-2",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1035300574",
"https://doi.org/10.1007/s10120-013-0322-2"
],
"type": "CreativeWork"
}
],
"datePublished": "2017-12-06",
"datePublishedReg": "2017-12-06",
"description": "BackgroundThe optimal management of precursor lesions such as gastric low-grade dysplasia is crucial in order to improve gastric cancer-related mortality. However, there are no universally accepted management guidelines regarding which lesions should be resected or should be monitored by follow-up visits.Patients and methodsWe retrospectively analyzed data from 1006 gastric low-grade dysplasia lesions that had been resected via endoscopic submucosal dissection. We also evaluated the endoscopic risk factors associated with upstage diagnosis from low-grade dysplasia to high-grade dysplasia or gastric cancer.ResultsThe mean age of our patients was 63.7\u2009\u00b1\u20099.1\u00a0years and 70.3% of our study population included men. The predominant location and gross type of lesions was the lower third of the stomach (78.6%) and the elevated type (57.8%), respectively. The rates of pathological concordance, upstage, and downstage diagnosis were 85.3, 12.1, and 2.6%, respectively. Multivariate analysis, after adjusting for age and sex, showed that a lesion size\u2009\u2265\u200910\u00a0mm (Odds ratio [OR] 2.231; p\u2009=\u20090.003), erythema (OR 7.315; p\u2009<\u20090.001), nodularity (OR 5.589; p\u2009<\u20090.001), depression (OR 3.024; p\u2009=\u20090.002), and erosion (OR 7.680; p\u2009<\u20090.001) were all factors significantly associated with upstage diagnosis. Furthermore, an increasing number of risk factors was associated with an increasing frequency of upstage diagnosis; if there were no risk factors, then there was no upstage diagnosis.ConclusionsThis study identified several risk factors that were significantly associated with the upstage diagnosis of gastric low-grade dysplasia: lesion size\u2009\u2265\u200910\u00a0mm and a variety of surface changes (erythema, nodularity, depression, and erosion). Our data indicate that if there is no evidence of these endoscopic risk factors, then regular follow-up may be considered, according to the patient\u2019s combined comorbid conditions.",
"genre": "article",
"id": "sg:pub.10.1007/s00464-017-5971-5",
"inLanguage": "en",
"isAccessibleForFree": false,
"isPartOf": [
{
"id": "sg:journal.1098220",
"issn": [
"0930-2794",
"1432-2218"
],
"name": "Surgical Endoscopy",
"publisher": "Springer Nature",
"type": "Periodical"
},
{
"issueNumber": "6",
"type": "PublicationIssue"
},
{
"type": "PublicationVolume",
"volumeNumber": "32"
}
],
"keywords": [
"gastric low-grade dysplasia",
"low-grade dysplasia",
"risk factors",
"endoscopic risk factors",
"lesion size",
"low-grade dysplasia lesions",
"ResultsThe mean age",
"gastric cancer-related mortality",
"cancer-related mortality",
"high-grade dysplasia",
"endoscopic submucosal dissection",
"endoscopic resection",
"comorbid conditions",
"mean age",
"submucosal dissection",
"gross type",
"precursor lesions",
"elevated type",
"gastric cancer",
"study population",
"dysplasia lesions",
"pathological concordance",
"multivariate analysis",
"dysplasia",
"optimal management",
"lesions",
"diagnosis",
"management guidelines",
"predominant location",
"ConclusionsThis study",
"patients",
"age",
"factors",
"resection",
"erythema",
"mortality",
"cancer",
"MethodsWe",
"stomach",
"nodularity",
"visits",
"dissection",
"upstage",
"depression",
"men",
"sex",
"predictors",
"concordance",
"guidelines",
"years",
"population",
"evidence",
"management",
"data",
"study",
"types",
"rate",
"changes",
"surface changes",
"frequency",
"number",
"size",
"analysis",
"variety",
"location",
"conditions",
"erosion",
"order"
],
"name": "Predictors of upstage diagnosis after endoscopic resection of gastric low-grade dysplasia",
"pagination": "2732-2738",
"productId": [
{
"name": "dimensions_id",
"type": "PropertyValue",
"value": [
"pub.1099694716"
]
},
{
"name": "doi",
"type": "PropertyValue",
"value": [
"10.1007/s00464-017-5971-5"
]
},
{
"name": "pubmed_id",
"type": "PropertyValue",
"value": [
"29214514"
]
}
],
"sameAs": [
"https://doi.org/10.1007/s00464-017-5971-5",
"https://app.dimensions.ai/details/publication/pub.1099694716"
],
"sdDataset": "articles",
"sdDatePublished": "2022-05-20T07:33",
"sdLicense": "https://scigraph.springernature.com/explorer/license/",
"sdPublisher": {
"name": "Springer Nature - SN SciGraph project",
"type": "Organization"
},
"sdSource": "s3://com-springernature-scigraph/baseset/20220519/entities/gbq_results/article/article_731.jsonl",
"type": "ScholarlyArticle",
"url": "https://doi.org/10.1007/s00464-017-5971-5"
}
]Download the RDF metadata as: json-ld nt turtle xml License info
JSON-LD is a popular format for linked data which is fully compatible with JSON.
curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00464-017-5971-5'
N-Triples is a line-based linked data format ideal for batch operations.
curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00464-017-5971-5'
Turtle is a human-readable linked data format.
curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00464-017-5971-5'
RDF/XML is a standard XML format for linked data.
curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00464-017-5971-5'
This table displays all metadata directly associated to this object as RDF triples.
266 TRIPLES
22 PREDICATES
117 URIs
100 LITERALS
21 BLANK NODES