Clinical features of negative pathologic results after gastric endoscopic submucosal dissection View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2016-07-12

AUTHORS

Dong Il Jeong, Hyung Wook Kim, Cheol Woong Choi, Dae Hwan Kang, Su Bum Park, Su Jin Kim, Hyeong Seok Nam

ABSTRACT

BackgroundEndoscopic submucosal dissection (ESD) is widely used for the treatment of gastric superficial neoplasms. Negative pathologic results after ESD can confuse the endoscopists and patients. The aim of this study was to evaluate the reasons for and the factors associated with negative pathologic results after ESD.Patients and methodsFrom December 2008 to July 2015, a total of 1379 lesions diagnosed as definite dysplasia or adenocarcinoma by endoscopic forceps biopsy (EFB) were removed with an ESD procedure. The initial endoscopic and pathologic findings were analyzed.ResultsThe incidence of negative pathology after ESD was 2.0 % (28/1379). Compared with positive pathologic lesions, negative pathologic lesions were smaller and had less surface area (P < 0.001). The reasons for negative pathologic lesions after ESD were complete removal by EFB (n = 20), over-estimations of the EFB specimen (n = 5), and different ESD site (n = 3).ConclusionSmall tumor size and surface area are associated with negative pathologic results after ESD. When negative pathologic results are reported after ESD, we should review the previous endoscopic biopsy tissue specimen and compare the previous EFB site to the ESD site. Thereafter, regular endoscopic examination of the lesion is needed. More... »

PAGES

1163-1171

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00464-016-5086-4

DOI

http://dx.doi.org/10.1007/s00464-016-5086-4

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1017274841

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/27405480


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