Ontology type: schema:ScholarlyArticle Open Access: True
2017-02
AUTHORSJ. Hunter Mehaffey, Mathew G. Mullen, Rachel L. Mehaffey, Florence E. Turrentine, Steven K. Malin, Jennifer L. Kirby, Bruce Schirmer, Peter T. Hallowell
ABSTRACTOBJECTIVE(S): Roux-en-Y Gastric Bypass (RYGB) is well known to ameliorate type 2 diabetes mellitus (T2DM), and recent work suggests that the preoperative DiaREM model predicts successful remission up to 1 year post-RYGB. However, no data exist for long-term validity. Therefore, we sought to determine the utility of this score on long-term RYGB effectiveness for T2DM resolution at 2 and 10 years, respectively. METHODS: T2DM patients (Age: 48, BMI: 49, HbA1C: 8.1) undergoing RYGB at the University of Virginia between 2004-2006 (n = 42) and 2012-2014 (n = 59) were evaluated prospectively to assess preoperative DiaREM score, defined from insulin use, age, HbA1C, and type of antidiabetic medication. T2DM partial remission status was based on the American Diabetes Association guidelines (HbA1C < 6.5 % and fasting glycemia <125 mg/dL, and no anti-diabetic medications). Chi-square test was used to compare patient's T2DM status to their DiaREM probability of remission. RESULTS: Among RYGB patients with 2-year postoperative data, 2 were lost (n = 1 no follow-up and n = 1 died) resulting in 57 patients for analysis. For the 10-year postoperative data, 11 were lost (n = 6 no follow-up and n = 5 died), thereby resulting in only 31 patients for analysis. Patients were distributed by DiaREM score to correlate with the predicted probability of remission as follows: 0-2 (Predicted 94 %, 2-year 100 % p = 0.61, 10-year 100 % p = 0.72), 3-7 (Predicted 76 %, 2-year 94 % p = 0.08, 10-year 83 % p = 0.57), 8-12 (Predicted 36 %, 2-year 47 % p = 0.38, 10-year 43 % p = 0.72), 13-17 (Predicted 22 %, 2-year 20 % p = 0.92, 10-year 33 % p = 0.64), and 18-22 (Predicted 9 %, 2-year 15 % p = 0.40, 10-year 14 % p = 0.64). CONCLUSIONS: Preoperative DiaREM scores are a good tool for predicting both short- and long-term T2DM remissions following RYGB. This study highlights the need to identify strategies that improve T2DM remission in those at highest risk. More... »
PAGES538-542
http://scigraph.springernature.com/pub.10.1007/s00464-016-4964-0
DOIhttp://dx.doi.org/10.1007/s00464-016-4964-0
DIMENSIONShttps://app.dimensions.ai/details/publication/pub.1031136402
PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/27177952
JSON-LD is the canonical representation for SciGraph data.
TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT
[
{
"@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json",
"about": [
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Clinical Sciences",
"type": "DefinedTerm"
},
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Medical and Health Sciences",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Adult",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Aged",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Aged, 80 and over",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Databases, Factual",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Decision Support Techniques",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Diabetes Mellitus, Type 2",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Female",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Follow-Up Studies",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Gastric Bypass",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Health Status Indicators",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Humans",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Male",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Middle Aged",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Retrospective Studies",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Treatment Outcome",
"type": "DefinedTerm"
}
],
"author": [
{
"affiliation": {
"alternateName": "University of Virginia",
"id": "https://www.grid.ac/institutes/grid.27755.32",
"name": [
"Department of Surgery, University of Virginia, Box 800709, 22903, Charlottesville, VA, USA"
],
"type": "Organization"
},
"familyName": "Mehaffey",
"givenName": "J. Hunter",
"id": "sg:person.0774241531.56",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0774241531.56"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Virginia",
"id": "https://www.grid.ac/institutes/grid.27755.32",
"name": [
"Department of Surgery, University of Virginia, Box 800709, 22903, Charlottesville, VA, USA"
],
"type": "Organization"
},
"familyName": "Mullen",
"givenName": "Mathew G.",
"id": "sg:person.013470052075.80",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013470052075.80"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Virginia",
"id": "https://www.grid.ac/institutes/grid.27755.32",
"name": [
"Department of Internal Medicine, University of Virginia, Box 800709, 22903, Charlottesville, VA, USA"
],
"type": "Organization"
},
"familyName": "Mehaffey",
"givenName": "Rachel L.",
"id": "sg:person.014265432475.36",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014265432475.36"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Virginia",
"id": "https://www.grid.ac/institutes/grid.27755.32",
"name": [
"Department of Surgery, University of Virginia, Box 800709, 22903, Charlottesville, VA, USA"
],
"type": "Organization"
},
"familyName": "Turrentine",
"givenName": "Florence E.",
"id": "sg:person.0742300777.09",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0742300777.09"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Virginia",
"id": "https://www.grid.ac/institutes/grid.27755.32",
"name": [
"Department of Kinesiology, University of Virginia, Box 800709, 22903, Charlottesville, VA, USA",
"Division of Endocrinology and Metabolism, University of Virginia, Box 800709, 22903, Charlottesville, VA, USA"
],
"type": "Organization"
},
"familyName": "Malin",
"givenName": "Steven K.",
"id": "sg:person.01064545154.58",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01064545154.58"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Virginia",
"id": "https://www.grid.ac/institutes/grid.27755.32",
"name": [
"Department of Internal Medicine, University of Virginia, Box 800709, 22903, Charlottesville, VA, USA",
"Division of Endocrinology and Metabolism, University of Virginia, Box 800709, 22903, Charlottesville, VA, USA"
],
"type": "Organization"
},
"familyName": "Kirby",
"givenName": "Jennifer L.",
"id": "sg:person.01047615510.48",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01047615510.48"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Virginia",
"id": "https://www.grid.ac/institutes/grid.27755.32",
"name": [
"Department of Surgery, University of Virginia, Box 800709, 22903, Charlottesville, VA, USA"
],
"type": "Organization"
},
"familyName": "Schirmer",
"givenName": "Bruce",
"id": "sg:person.01273031731.58",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01273031731.58"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Virginia",
"id": "https://www.grid.ac/institutes/grid.27755.32",
"name": [
"Department of Surgery, University of Virginia, Box 800709, 22903, Charlottesville, VA, USA"
],
"type": "Organization"
},
"familyName": "Hallowell",
"givenName": "Peter T.",
"id": "sg:person.01030045032.66",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01030045032.66"
],
"type": "Person"
}
],
"citation": [
{
"id": "sg:pub.10.1007/s11892-015-0590-9",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1000747601",
"https://doi.org/10.1007/s11892-015-0590-9"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s11695-013-1121-x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1001059215",
"https://doi.org/10.1007/s11695-013-1121-x"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s11695-015-1603-0",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1002817990",
"https://doi.org/10.1007/s11695-015-1603-0"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s11695-015-1662-2",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1003422434",
"https://doi.org/10.1007/s11695-015-1662-2"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s2213-8587(13)70202-x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1006686178"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/sla.0000000000001544",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1011431204"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/sla.0000000000001544",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1011431204"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s2213-8587(13)70070-6",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1012218613"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1001/jamasurg.2015.3231",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1014035926"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/oby.21021",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1015755904"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/oby.21021",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1015755904"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s11695-014-1511-8",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1019224538",
"https://doi.org/10.1007/s11695-014-1511-8"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s11695-016-2122-3",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1020419635",
"https://doi.org/10.1007/s11695-016-2122-3"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/dom.12376",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1020950944"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1001/archinte.163.18.2146",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1022076323"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1056/nejmoa1401329",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1022919270"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0140-6736(11)60814-3",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1025087671"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.2337/dc12-s011",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1026975709"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1001/jama.286.10.1195",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1028638756"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s11695-015-1823-3",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1029299618",
"https://doi.org/10.1007/s11695-015-1823-3"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.suc.2011.04.008",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1030526820"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.2337/dc12-1596",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1035048348"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/00000658-198709000-00009",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1036366460"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/00000658-198709000-00009",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1036366460"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.jamcollsurg.2005.03.021",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1037932755"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.jamcollsurg.2005.03.021",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1037932755"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1001/jama.2014.5988",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1039396191"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.amjsurg.2009.11.007",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1039871146"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/sla.0000000000000863",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1046639590"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/sla.0000000000000863",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1046639590"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.3748/wjg.v19.i39.6590",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1071369798"
],
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1077373871",
"type": "CreativeWork"
}
],
"datePublished": "2017-02",
"datePublishedReg": "2017-02-01",
"description": "OBJECTIVE(S): Roux-en-Y Gastric Bypass (RYGB) is well known to ameliorate type 2 diabetes mellitus (T2DM), and recent work suggests that the preoperative DiaREM model predicts successful remission up to 1\u00a0year post-RYGB. However, no data exist for long-term validity. Therefore, we sought to determine the utility of this score on long-term RYGB effectiveness for T2DM resolution at 2 and 10\u00a0years, respectively.\nMETHODS: T2DM patients (Age: 48, BMI: 49, HbA1C: 8.1) undergoing RYGB at the University of Virginia between 2004-2006 (n\u00a0=\u00a042) and 2012-2014 (n\u00a0=\u00a059) were evaluated prospectively to assess preoperative DiaREM score, defined from insulin use, age, HbA1C, and type of antidiabetic medication. T2DM partial remission status was based on the American Diabetes Association guidelines (HbA1C\u00a0<\u00a06.5\u00a0% and fasting glycemia <125\u00a0mg/dL, and no anti-diabetic medications). Chi-square test was used to compare patient's T2DM status to their DiaREM probability of remission.\nRESULTS: Among RYGB patients with 2-year postoperative data, 2 were lost (n\u00a0=\u00a01 no follow-up and n\u00a0=\u00a01 died) resulting in 57 patients for analysis. For the 10-year postoperative data, 11 were lost (n\u00a0=\u00a06 no follow-up and n\u00a0=\u00a05 died), thereby resulting in only 31 patients for analysis. Patients were distributed by DiaREM score to correlate with the predicted probability of remission as follows: 0-2 (Predicted 94\u00a0%, 2-year 100\u00a0% p\u00a0=\u00a00.61, 10-year 100\u00a0% p\u00a0=\u00a00.72), 3-7 (Predicted 76\u00a0%, 2-year 94\u00a0% p\u00a0=\u00a00.08, 10-year 83\u00a0% p\u00a0=\u00a00.57), 8-12 (Predicted 36\u00a0%, 2-year 47\u00a0% p\u00a0=\u00a00.38, 10-year 43\u00a0% p\u00a0=\u00a00.72), 13-17 (Predicted 22\u00a0%, 2-year 20\u00a0% p\u00a0=\u00a00.92, 10-year 33\u00a0% p\u00a0=\u00a00.64), and 18-22 (Predicted 9\u00a0%, 2-year 15\u00a0% p\u00a0=\u00a00.40, 10-year 14\u00a0% p\u00a0=\u00a00.64).\nCONCLUSIONS: Preoperative DiaREM scores are a good tool for predicting both short- and long-term T2DM remissions following RYGB. This study highlights the need to identify strategies that improve T2DM remission in those at highest risk.",
"genre": "research_article",
"id": "sg:pub.10.1007/s00464-016-4964-0",
"inLanguage": [
"en"
],
"isAccessibleForFree": true,
"isFundedItemOf": [
{
"id": "sg:grant.2684851",
"type": "MonetaryGrant"
}
],
"isPartOf": [
{
"id": "sg:journal.1098220",
"issn": [
"0930-2794",
"1432-2218"
],
"name": "Surgical Endoscopy",
"type": "Periodical"
},
{
"issueNumber": "2",
"type": "PublicationIssue"
},
{
"type": "PublicationVolume",
"volumeNumber": "31"
}
],
"name": "Type 2 diabetes remission following gastric bypass: does diarem stand the test of time?",
"pagination": "538-542",
"productId": [
{
"name": "readcube_id",
"type": "PropertyValue",
"value": [
"94549c001d267aaeac6e19727ed11b6b05c6ef6fd2ff88c4f7abab212a7fb712"
]
},
{
"name": "pubmed_id",
"type": "PropertyValue",
"value": [
"27177952"
]
},
{
"name": "nlm_unique_id",
"type": "PropertyValue",
"value": [
"8806653"
]
},
{
"name": "doi",
"type": "PropertyValue",
"value": [
"10.1007/s00464-016-4964-0"
]
},
{
"name": "dimensions_id",
"type": "PropertyValue",
"value": [
"pub.1031136402"
]
}
],
"sameAs": [
"https://doi.org/10.1007/s00464-016-4964-0",
"https://app.dimensions.ai/details/publication/pub.1031136402"
],
"sdDataset": "articles",
"sdDatePublished": "2019-04-10T17:26",
"sdLicense": "https://scigraph.springernature.com/explorer/license/",
"sdPublisher": {
"name": "Springer Nature - SN SciGraph project",
"type": "Organization"
},
"sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8672_00000489.jsonl",
"type": "ScholarlyArticle",
"url": "http://link.springer.com/10.1007/s00464-016-4964-0"
}
]Download the RDF metadata as: json-ld nt turtle xml License info
JSON-LD is a popular format for linked data which is fully compatible with JSON.
curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00464-016-4964-0'
N-Triples is a line-based linked data format ideal for batch operations.
curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00464-016-4964-0'
Turtle is a human-readable linked data format.
curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00464-016-4964-0'
RDF/XML is a standard XML format for linked data.
curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00464-016-4964-0'
This table displays all metadata directly associated to this object as RDF triples.
270 TRIPLES
21 PREDICATES
71 URIs
36 LITERALS
24 BLANK NODES