Clinical outcomes of re-stenting in patients with stent malfunction in malignant gastric outlet obstruction View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2015-07-03

AUTHORS

Eun Hyo Jin, Sang Gyun Kim, Ji Yeon Seo, Jong Pil Im, Joo Sung Kim, Hyun Chae Jung

ABSTRACT

Background and aimsSelf-expanding metal stents (SEMS) have been used for the palliative treatment of malignant gastric outlet obstruction (GOO). The aim of this study was to evaluate the clinical outcomes of salvage SEMS for stent malfunction and to identify the prognostic factors for a longer patency.MethodsA total of 108 patients who underwent a secondary salvage SEMS placement for a primary stent malfunction were retrospectively reviewed at the Seoul National University Hospital between August 2004 and May 2013. The duration of patency for salvage SEMS was defined as the time between salvage SEMS placement and the recurrence of obstructive symptoms that were confirmed either endoscopically or radiologically.ResultsThe technical and clinical success rates for salvage SEMS were 100 and 82.4 % (95 % confidence interval [CI] 74.0–89.0), respectively. A salvage SEMS malfunction occurred in 29 (26.9 %) of the 108 patients. The median duration of patency for salvage SEMS was 59.5 days (range 3–928, 95 % CI 73.7–118.3). Longer SEMS patencies of more than 60 days were significantly associated with palliative chemotherapy (odds ratio = 2.539, 95 % CI 1.031–6.252, p = .043). For salvage SEMS, covered–uncovered stents had a longer patency duration, as compared with other combinations of primary and salvage stent types.ConclusionsLonger patency durations for salvage SEMS were associated with palliative chemotherapy after salvage SEMS insertion. Salvage SEMS could be a feasible and effective treatment for primary stent malfunction in malignant GOO. More... »

PAGES

1372-1379

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00464-015-4338-z

DOI

http://dx.doi.org/10.1007/s00464-015-4338-z

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1006460023

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/26139493


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