Predictive factors associated with postoperative pancreatic fistula after laparoscopic distal pancreatectomy: a 10-year single-institution experience View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2015-06-20

AUTHORS

Arturo S. Mendoza, Ho-Seong Han, Soyeon Ahn, Yoo-Seok Yoon, Jai Young Cho, YoungRok Choi

ABSTRACT

BackgroundLaparoscopic distal pancreatectomy (LDP) is a treatment option for benign and borderline pancreatic tumors. However, pancreatic fistula (PF) remains a significant morbidity, contributing to the length of hospital stay and overall costs. In a consecutive series of 143 patients at a single institution, the predictive factors associated with PF after LDP were identified.MethodsA retrospective study of patients who had undergone LDP between January 2003 and December 2013 was conducted. Patient demographic data and clinicopathological parameters were analyzed to evaluate their correlation with the incidence of PF.ResultsAmong the 143 patients, the indications for surgery were benign disease in 117 (82 %) and malignant tumors in 26 (18 %). PF occurred in 25 (17 %) patients, 10 (40 %) of whom had clinically significant (grade B) PF. No grade C PF was observed. Multivariable analysis showed that pancreatic thickness was a significant predictive factor for PF (P < 0.001). A 12-mm cutoff value was based on the median pancreatic thickness in this series. Pancreatic texture alone was not a significant risk factor (P = 0.30); however, it became significant in patients with pancreatic thickness exceeding 12 mm (P = 0.005).ConclusionsPancreatic thickness exceeding 12 mm significantly increases the likelihood of PF after LDP. Pancreatic texture alone is not an independent risk factor for PF, but when combined with a thick parenchyma (>12 mm), a soft pancreas is predictive of PF. More... »

PAGES

649-656

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00464-015-4255-1

DOI

http://dx.doi.org/10.1007/s00464-015-4255-1

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1029770114

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/26091993


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