Mechanisms responsible for recurrent gastroesophageal reflux in neurologically impaired children who underwent laparoscopic Nissen fundoplication View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2002-02-08

AUTHORS

H. Kawahara, K. Nakajima, M. Yagi, H. Okuyama, A. Kubota, A. Okada

ABSTRACT

BackgroundIn this study, we attempted to define the lower esophageal sphincter (LES) motor events associated with the occurrence of gastroesophageal reflux (GER) in neurologically impaired children in whom of GER disease recurred after laparoscopic Nissen fundoplication (LNF).MethodsOf 45 neurologically impaired children who had previously undergone LNF, six children in whom recurrence of GER disease was documented by 24-h esophageal pH monitoring were studied. Concurrent esophageal manometry and pH monitoring were conducted for 1 h both before and after the administration of apple juice (10 ml/kg).ResultsA total of 89 reflux episodes were recorded in the course of the study. Of these, 51 episodes (57%) were associated with transient LES relaxation. In the remainder, reflux occurred across a contracted LES in 21 episodes (24%) and during absent basal LES tone in 15 episodes (17%). In four of six patients, transient LES relaxation was responsible for more than half of the reflux episodes.ConclusionTransient LES relaxation is the predominant mechanism of reflux in neurologically impaired children with recurrent GER after LNF. More... »

PAGES

767-771

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00464-001-8228-1

DOI

http://dx.doi.org/10.1007/s00464-001-8228-1

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1008337217

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/11997818


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