Solid Oral Dosage Forms Use in Adults with Neurological Disorders and Swallowing Difficulties: A Scoping Review View Full Text


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Article Info

DATE

2021-10-15

AUTHORS

Carolina Justus Buhrer Ferreira-Neto, Rayza Assis de Andrade, Fernanda Stumpf Tonin, Astrid Wiens

ABSTRACT

Swallowing difficulties affects the deglutition of solid oral dosage forms (SODFs) and it is a common problem among neurological disorders. Interventions may improve the use of SODFs in healthcare settings. The aim of this study was to map the available research about the interventions aiming the effective and safe use of SODFs in adults with neurological disorders and swallowing difficulties and to identify potential literature gaps in this scientific field. A scoping review was carried out based on Joanna Briggs Institute guidelines and reported according to the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses Extension for Scoping Reviews, in PubMed, Scopus, and SciELO databases (March 2021). Peer-reviewed observational studies assessed the effectiveness and safety of SODFs in adults with neurological disorders and swallowing difficulties in the healthcare organizations setting were included. 11 studies were included (three case reports, two mixed-methods intervention studies, and six analytic studies). The frequency of women ranged from 49 to 67%, and the age from 57 to 91 years. Most studies (n = 7) included elderly patients, Parkinson (n = 6) and dementia (n = 3). Medication review was the most frequently reported intervention, 35% (9/26). In most studies, interventions were targeted to patients during hospitalization (n = 7) and performed by physicians (n = 8). At least 20 different outcomes were evaluated in the studies. Implementing specific protocols for using SODFs aimed at the swallowing difficulties of this population is not a common practice. Additional studies on interventions aimed at optimizing SODFs are needed to support the safety and efficacy of oral therapy in this patient group. More... »

PAGES

1-14

References to SciGraph publications

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  • 2015-07-24. Swallowing Tablets and Capsules Increases the Risk of Penetration and Aspiration in Patients with Stroke-Induced Dysphagia in DYSPHAGIA
  • 2020-06-07. Dysphagia in neurological diseases: a literature review in NEUROLOGICAL SCIENCES
  • 2010-01-23. Omission of Dysphagia Therapies in Hospital Discharge Communications in DYSPHAGIA
  • 2012-09-29. Difficulties swallowing solid oral dosage forms in a general practice population: prevalence, causes, and relationship to dosage forms in EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
  • 2017-02-20. Assessment of clinical practices for crushing medication in geriatric units in THE JOURNAL OF NUTRITION, HEALTH & AGING
  • 2013-05-01. Thickening agents used for dysphagia management: effect on bioavailability of water, medication and feelings of satiety in NUTRITION JOURNAL
  • 2014-01-28. Inappropriate crushing information on ward lists: cytotoxic drugs, capsules, and modified release formulations are gravely neglected in EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
  • 2015-11-16. Older adults with difficulty swallowing oral medicines: a systematic review of the literature in EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
  • 2013-08-21. Swallowing difficulties with oral drugs among polypharmacy patients attending community pharmacies in INTERNATIONAL JOURNAL OF CLINICAL PHARMACY
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