Effect of shear rate on hybridoma cell metabolism View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1997-05

AUTHORS

N. Shiragami

ABSTRACT

The effect of shear rate on cell growth and monoclonal antibody production of hybridoma cells was studied. The dependence of agitation rate on antibody production is discussed by measuring the amount of monoclonal antibody in cells cultured by a spinner vessel. The effect of shear rate is also studied by exposing a homogeneous shear flow to hybridoma cells in a cone-and-plate viscometer. The dependence of shear rate on hybridoma cells was observed and the increase of antibody production was arised from the increase of secretion from cells. More... »

PAGES

345-347

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s004490050333

DOI

http://dx.doi.org/10.1007/s004490050333

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1007068959


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