Sucrose-enhanced biosynthesis of medicinally important antioxidant secondary metabolites in cell suspension cultures of Artemisia absinthium L. View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2016-12

AUTHORS

Mohammad Ali, Bilal Haider Abbasi, Nisar Ahmad, Syed Shujait Ali, Shahid Ali, Gul Shad Ali

ABSTRACT

Natural products are gaining tremendous importance in pharmaceutical industry and attention has been focused on the applications of in vitro technologies to enhance yield and productivity of such products. In this study, we investigated the accumulation of biomass and antioxidant secondary metabolites in response to different carbohydrate sources (sucrose, maltose, fructose and glucose) and sucrose concentrations (1, 3, 5, 7 and 9 %). Moreover, the effects of 3 % repeated sucrose feeding (day-12, -18 and -24) were also investigated. The results showed the superiority of disaccharides over monosaccharides for maximum biomass and secondary metabolites accumulation. Comparable profiles for maximum biomass were observed in response to sucrose and maltose and initial sucrose concentrations of 3 and 5 %. Maximum total phenolic and total flavonoid contents were displayed by cultures treated with sucrose and maltose; however, initial sucrose concentrations of 5 and 7 % were optimum for both classes of metabolites, respectively. Following 3 % extra sucrose feeding, cultures fed on day-24 (late-log phase) showed higher biomass, total phenolic and total flavonoid contents as compared to control cultures. Highest antioxidant activity was exhibited by maltose-treated cultures. Moreover, sucrose-treated cultures displayed positive correlation of antioxidant activity with total phenolics and total flavonoids production. This work describes the stimulatory role of disaccharides and sucrose feeding strategy for higher accumulation of phenolics and flavonoids, which could be potentially scaled up to bioreactor level for the bulk production of these metabolites in suspension cultures of A. absinthium. More... »

PAGES

1945-1954

References to SciGraph publications

  • 2012-11. Accumulation of rosmarinic, chlorogenic and caffeic acids in in vitro cultures of Eryngium planum L. in ACTA PHYSIOLOGIAE PLANTARUM
  • 1999-01. Shear stress effects on plant cell suspension cultures in a rotating wall vessel bioreactor in JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY
  • 2007-07. Sugars proportionately affect artemisinin production in PLANT CELL REPORTS
  • 2016-03. Sucrose induced osmotic stress and photoperiod regimes enhanced the biomass and production of antioxidant secondary metabolites in shake-flask suspension cultures of Prunella vulgaris L. in PLANT CELL, TISSUE AND ORGAN CULTURE (PCTOC)
  • 2012-03. Sucrose regulated enhanced induction of anthraquinone, phenolics, flavonoids biosynthesis and activities of antioxidant enzymes in adventitious root suspension cultures of Morinda citrifolia (L.) in ACTA PHYSIOLOGIAE PLANTARUM
  • 2015-03. Elicitation of antioxidant secondary metabolites with jasmonates and gibberellic acid in cell suspension cultures of Artemisia absinthium L. in PLANT CELL, TISSUE AND ORGAN CULTURE (PCTOC)
  • 1991-03. Sucrose-dependent H+ transport in plasma-membrane vesicles isolated from sugarbeet leaves (Beta vulgaris L.) in PLANTA
  • 1997-04. Enhanced production of taxol in suspension cultures of Taxus chinensis by controlling inoculum size in BIOTECHNOLOGY LETTERS
  • 2004-11. Alteration of biomass and artemisinin production in Artemisia annua hairy roots by media sterilization method and sugars in PLANT CELL REPORTS
  • 2010-10. Sucrose-induced osmotic stress affects biomass, metabolite, and antioxidant levels in root suspension cultures of Hypericum perforatum L. in PLANT CELL, TISSUE AND ORGAN CULTURE (PCTOC)
  • 2013-09. Production of salidroside and tyrosol in cell suspension cultures of Rhodiola crenulata in PLANT CELL, TISSUE AND ORGAN CULTURE (PCTOC)
  • 2000-08. Sugar utilization and invertase activity in hairy-root and cell-suspension cultures of Symphytum officinale in PLANT CELL, TISSUE AND ORGAN CULTURE (PCTOC)
  • 1998-10. Culture-induced changes in osmolality of tobacco cell suspensions using four exogenous sugars in PLANT CELL, TISSUE AND ORGAN CULTURE (PCTOC)
  • 2006-06. Optimization of culturing conditions for the production of biomass and phenolics from adventitious roots ofEchinacea angustifolia in JOURNAL OF PLANT BIOLOGY
  • 2012-07. Artemisia absinthium (AA): a novel potential complementary and alternative medicine for breast cancer in MOLECULAR BIOLOGY REPORTS
  • 2007-02. Differential sugar uptake by cell suspension cultures of Rudgea jasminoides, a tropical woody Rubiaceae in IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY - PLANT
  • 2012-12. Evaluation of antioxidant and cytoprotective activities of Arnica montana L. and Artemisia absinthiumL. ethanolic extracts in CHEMISTRY CENTRAL JOURNAL
  • 2013-07. Culture medium optimization for camptothecin production in cell suspension cultures of Nothapodytes nimmoniana (J. Grah.) Mabberley in PLANT BIOTECHNOLOGY REPORTS
  • 1990-04. Effect of carbon and nitrogen sources on growth and solasodine production in batch suspension cultures of Solanum eleagnifolium Cav. in PLANT CELL, TISSUE AND ORGAN CULTURE (PCTOC)
  • 2002-08. Effect of sucrose on adventitious root regeneration in apple in PLANT CELL, TISSUE AND ORGAN CULTURE (PCTOC)
  • 2010-06. Shoot regeneration and free-radical scavenging activity in Silybum marianum L. in PLANT CELL, TISSUE AND ORGAN CULTURE (PCTOC)
  • 1995-01. Production of taxol and related taxanes in Taxus brevifolia cell cultures: Effect of sugar in BIOTECHNOLOGY LETTERS
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s00449-016-1668-8

    DOI

    http://dx.doi.org/10.1007/s00449-016-1668-8

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1047837183

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/27515537


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1115", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Pharmacology and Pharmaceutical Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Medical and Health Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Antioxidants", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Artemisia absinthium", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Flavonoids", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Plant Cells", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Sucrose", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "affiliation": {
              "alternateName": "University of Swat", 
              "id": "https://www.grid.ac/institutes/grid.449683.4", 
              "name": [
                "Department of Biotechnology, Faculty of Biological Sciences, Quaid-i-Azam University, 45320, Islamabad, Pakistan", 
                "Center for Biotechnology and Microbiology, University of Swat, 19200, Swat, Pakistan"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Ali", 
            "givenName": "Mohammad", 
            "id": "sg:person.01011136722.23", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01011136722.23"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Quaid-i-Azam University", 
              "id": "https://www.grid.ac/institutes/grid.412621.2", 
              "name": [
                "Department of Biotechnology, Faculty of Biological Sciences, Quaid-i-Azam University, 45320, Islamabad, Pakistan"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Abbasi", 
            "givenName": "Bilal Haider", 
            "id": "sg:person.0605500545.25", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0605500545.25"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Swat", 
              "id": "https://www.grid.ac/institutes/grid.449683.4", 
              "name": [
                "Center for Biotechnology and Microbiology, University of Swat, 19200, Swat, Pakistan"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Ahmad", 
            "givenName": "Nisar", 
            "id": "sg:person.01214656245.79", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01214656245.79"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Swat", 
              "id": "https://www.grid.ac/institutes/grid.449683.4", 
              "name": [
                "Center for Biotechnology and Microbiology, University of Swat, 19200, Swat, Pakistan"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Ali", 
            "givenName": "Syed Shujait", 
            "id": "sg:person.01240452675.58", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01240452675.58"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Swat", 
              "id": "https://www.grid.ac/institutes/grid.449683.4", 
              "name": [
                "Center for Biotechnology and Microbiology, University of Swat, 19200, Swat, Pakistan"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Ali", 
            "givenName": "Shahid", 
            "id": "sg:person.0626435151.00", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0626435151.00"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Florida", 
              "id": "https://www.grid.ac/institutes/grid.15276.37", 
              "name": [
                "Mid-Florida Research and Education Center and Department of Plant Pathology, University of Florida/Institute of Food and Agricultural Sciences, 2725 Binion Rd, 32703, Apopka, FL, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Ali", 
            "givenName": "Gul Shad", 
            "id": "sg:person.01301657501.38", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01301657501.38"
            ], 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "sg:pub.10.1023/a:1026506426420", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002502012", 
              "https://doi.org/10.1023/a:1026506426420"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.procbio.2005.09.005", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003777905"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.procbio.2005.09.005", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003777905"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.5897/ajpp12.945", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1007862401"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0141-0229(95)00033-x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008243291"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.biortech.2008.09.028", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1011027140"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.procbio.2006.09.008", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1011175371"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf00034492", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1013226533", 
              "https://doi.org/10.1007/bf00034492"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf00034492", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1013226533", 
              "https://doi.org/10.1007/bf00034492"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf00194280", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1016153691", 
              "https://doi.org/10.1007/bf00194280"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/1752-153x-6-97", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1017722208", 
              "https://doi.org/10.1186/1752-153x-6-97"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1104/pp.105.072579", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018120339"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.biortech.2010.03.078", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018528849"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1146/annurev.arplant.47.1.509", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1020396519"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf03030532", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1020516142", 
              "https://doi.org/10.1007/bf03030532"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s11240-010-9692-x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021931568", 
              "https://doi.org/10.1007/s11240-010-9692-x"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s11240-010-9692-x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021931568", 
              "https://doi.org/10.1007/s11240-010-9692-x"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/jsfa.1950", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1023024264"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1399-3054.1962.tb08052.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1023703429"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00299-006-0295-2", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024385831", 
              "https://doi.org/10.1007/s00299-006-0295-2"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00299-006-0295-2", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024385831", 
              "https://doi.org/10.1007/s00299-006-0295-2"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00299-006-0295-2", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024385831", 
              "https://doi.org/10.1007/s00299-006-0295-2"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s11738-011-0837-2", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024570303", 
              "https://doi.org/10.1007/s11738-011-0837-2"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s11816-012-0270-z", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1025329712", 
              "https://doi.org/10.1007/s11816-012-0270-z"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s11240-015-0915-z", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1025376396", 
              "https://doi.org/10.1007/s11240-015-0915-z"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1023/a:1026472527872", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1026068177", 
              "https://doi.org/10.1023/a:1026472527872"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.plaphy.2005.02.011", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1029608101"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s11738-012-1011-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031621848", 
              "https://doi.org/10.1007/s11738-012-1011-1"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s11738-012-1011-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031621848", 
              "https://doi.org/10.1007/s11738-012-1011-1"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.phytochem.2008.02.014", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1032386991"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s11240-014-0666-2", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1032588869", 
              "https://doi.org/10.1007/s11240-014-0666-2"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0168-1656(96)01560-x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034322193"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/bp0001359", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036220535"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/sj.jim.2900600", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036235223", 
              "https://doi.org/10.1038/sj.jim.2900600"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s11627-006-9001-x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036875974", 
              "https://doi.org/10.1007/s11627-006-9001-x"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s11240-013-0325-z", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1037782588", 
              "https://doi.org/10.1007/s11240-013-0325-z"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00299-004-0837-4", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038316092", 
              "https://doi.org/10.1007/s00299-004-0837-4"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00299-004-0837-4", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038316092", 
              "https://doi.org/10.1007/s00299-004-0837-4"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00299-004-0837-4", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038316092", 
              "https://doi.org/10.1007/s00299-004-0837-4"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s11240-010-9747-z", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039213008", 
              "https://doi.org/10.1007/s11240-010-9747-z"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s11240-010-9747-z", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039213008", 
              "https://doi.org/10.1007/s11240-010-9747-z"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1177/1082013211399495", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040875118"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1177/1082013211399495", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040875118"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.indcrop.2013.05.033", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1041123082"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s11033-012-1569-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043617465", 
              "https://doi.org/10.1007/s11033-012-1569-0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.phymed.2009.10.013", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1044823483"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1146/annurev.arplant.57.032905.105441", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1044874917"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.jphotobiol.2014.08.008", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1045799107"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0032-9592(99)00094-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048267696"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1515/znc-2009-1-212", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048668239"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1023/a:1018355002041", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048997245", 
              "https://doi.org/10.1023/a:1018355002041"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf00134204", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050375018", 
              "https://doi.org/10.1007/bf00134204"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf00134204", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050375018", 
              "https://doi.org/10.1007/bf00134204"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1023/a:1016356123367", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1052147173", 
              "https://doi.org/10.1023/a:1016356123367"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/jf9801973", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1055930243"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/jf9801973", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1055930243"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/jm010359d", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1055946658"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/jm010359d", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1055946658"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1055/s-2003-37714", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1057420319"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1105/tpc.010455", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1075064431"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1078417735", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1078456478", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1078882817", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.18388/abp.2014_1922", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1078882817"
            ], 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "2016-12", 
        "datePublishedReg": "2016-12-01", 
        "description": "Natural products are gaining tremendous importance in pharmaceutical industry and attention has been focused on the applications of in vitro technologies to enhance yield and productivity of such products. In this study, we investigated the accumulation of biomass and antioxidant secondary metabolites in response to different carbohydrate sources (sucrose, maltose, fructose and glucose) and sucrose concentrations (1, 3, 5, 7 and 9\u00a0%). Moreover, the effects of 3\u00a0% repeated sucrose feeding (day-12, -18 and -24) were also investigated. The results showed the superiority of disaccharides over monosaccharides for maximum biomass and secondary metabolites accumulation. Comparable profiles for maximum biomass were observed in response to sucrose and maltose and initial sucrose concentrations of 3 and 5\u00a0%. Maximum total phenolic and total flavonoid contents were displayed by cultures treated with sucrose and maltose; however, initial sucrose concentrations of 5 and 7\u00a0% were optimum for both classes of metabolites, respectively. Following 3\u00a0% extra sucrose feeding, cultures fed on day-24 (late-log phase) showed higher biomass, total phenolic and total flavonoid contents as compared to control cultures. Highest antioxidant activity was exhibited by maltose-treated cultures. Moreover, sucrose-treated cultures displayed positive correlation of antioxidant activity with total phenolics and total flavonoids production. This work describes the stimulatory role of disaccharides and sucrose feeding strategy for higher accumulation of phenolics and flavonoids, which could be potentially scaled up to bioreactor level for the bulk production of these metabolites in suspension cultures of A. absinthium.", 
        "genre": "research_article", 
        "id": "sg:pub.10.1007/s00449-016-1668-8", 
        "inLanguage": [
          "en"
        ], 
        "isAccessibleForFree": false, 
        "isPartOf": [
          {
            "id": "sg:journal.1297453", 
            "issn": [
              "1615-7591", 
              "1615-7605"
            ], 
            "name": "Bioprocess and Biosystems Engineering", 
            "type": "Periodical"
          }, 
          {
            "issueNumber": "12", 
            "type": "PublicationIssue"
          }, 
          {
            "type": "PublicationVolume", 
            "volumeNumber": "39"
          }
        ], 
        "name": "Sucrose-enhanced biosynthesis of medicinally important antioxidant secondary metabolites in cell suspension cultures of Artemisia absinthium L.", 
        "pagination": "1945-1954", 
        "productId": [
          {
            "name": "readcube_id", 
            "type": "PropertyValue", 
            "value": [
              "e3e26504378fb5e2cdb74a3317a4243f469c8883e025c4bb63598771599f8db6"
            ]
          }, 
          {
            "name": "pubmed_id", 
            "type": "PropertyValue", 
            "value": [
              "27515537"
            ]
          }, 
          {
            "name": "nlm_unique_id", 
            "type": "PropertyValue", 
            "value": [
              "101088505"
            ]
          }, 
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1007/s00449-016-1668-8"
            ]
          }, 
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1047837183"
            ]
          }
        ], 
        "sameAs": [
          "https://doi.org/10.1007/s00449-016-1668-8", 
          "https://app.dimensions.ai/details/publication/pub.1047837183"
        ], 
        "sdDataset": "articles", 
        "sdDatePublished": "2019-04-11T12:35", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000363_0000000363/records_70027_00000002.jsonl", 
        "type": "ScholarlyArticle", 
        "url": "https://link.springer.com/10.1007%2Fs00449-016-1668-8"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00449-016-1668-8'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00449-016-1668-8'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00449-016-1668-8'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00449-016-1668-8'


     

    This table displays all metadata directly associated to this object as RDF triples.

    303 TRIPLES      21 PREDICATES      85 URIs      26 LITERALS      14 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1007/s00449-016-1668-8 schema:about N234b770a0e2a442697c5bc0884e363ab
    2 N3a3ce6e0bf2a4965bf2424e8b47e3b25
    3 N67ed9c0ff32b4112a621915b76acd7fe
    4 Na6fe966db41d40fe9b0f56c946ce6e49
    5 Nf2d0980646a245329322bae519ee65bb
    6 anzsrc-for:11
    7 anzsrc-for:1115
    8 schema:author Ndf489403e89f43a8ab66191ecca17f95
    9 schema:citation sg:pub.10.1007/bf00034492
    10 sg:pub.10.1007/bf00134204
    11 sg:pub.10.1007/bf00194280
    12 sg:pub.10.1007/bf03030532
    13 sg:pub.10.1007/s00299-004-0837-4
    14 sg:pub.10.1007/s00299-006-0295-2
    15 sg:pub.10.1007/s11033-012-1569-0
    16 sg:pub.10.1007/s11240-010-9692-x
    17 sg:pub.10.1007/s11240-010-9747-z
    18 sg:pub.10.1007/s11240-013-0325-z
    19 sg:pub.10.1007/s11240-014-0666-2
    20 sg:pub.10.1007/s11240-015-0915-z
    21 sg:pub.10.1007/s11627-006-9001-x
    22 sg:pub.10.1007/s11738-011-0837-2
    23 sg:pub.10.1007/s11738-012-1011-1
    24 sg:pub.10.1007/s11816-012-0270-z
    25 sg:pub.10.1023/a:1016356123367
    26 sg:pub.10.1023/a:1018355002041
    27 sg:pub.10.1023/a:1026472527872
    28 sg:pub.10.1023/a:1026506426420
    29 sg:pub.10.1038/sj.jim.2900600
    30 sg:pub.10.1186/1752-153x-6-97
    31 https://app.dimensions.ai/details/publication/pub.1078417735
    32 https://app.dimensions.ai/details/publication/pub.1078456478
    33 https://app.dimensions.ai/details/publication/pub.1078882817
    34 https://doi.org/10.1002/jsfa.1950
    35 https://doi.org/10.1016/0141-0229(95)00033-x
    36 https://doi.org/10.1016/0168-1656(96)01560-x
    37 https://doi.org/10.1016/j.biortech.2008.09.028
    38 https://doi.org/10.1016/j.biortech.2010.03.078
    39 https://doi.org/10.1016/j.indcrop.2013.05.033
    40 https://doi.org/10.1016/j.jphotobiol.2014.08.008
    41 https://doi.org/10.1016/j.phymed.2009.10.013
    42 https://doi.org/10.1016/j.phytochem.2008.02.014
    43 https://doi.org/10.1016/j.plaphy.2005.02.011
    44 https://doi.org/10.1016/j.procbio.2005.09.005
    45 https://doi.org/10.1016/j.procbio.2006.09.008
    46 https://doi.org/10.1016/s0032-9592(99)00094-1
    47 https://doi.org/10.1021/bp0001359
    48 https://doi.org/10.1021/jf9801973
    49 https://doi.org/10.1021/jm010359d
    50 https://doi.org/10.1055/s-2003-37714
    51 https://doi.org/10.1104/pp.105.072579
    52 https://doi.org/10.1105/tpc.010455
    53 https://doi.org/10.1111/j.1399-3054.1962.tb08052.x
    54 https://doi.org/10.1146/annurev.arplant.47.1.509
    55 https://doi.org/10.1146/annurev.arplant.57.032905.105441
    56 https://doi.org/10.1177/1082013211399495
    57 https://doi.org/10.1515/znc-2009-1-212
    58 https://doi.org/10.18388/abp.2014_1922
    59 https://doi.org/10.5897/ajpp12.945
    60 schema:datePublished 2016-12
    61 schema:datePublishedReg 2016-12-01
    62 schema:description Natural products are gaining tremendous importance in pharmaceutical industry and attention has been focused on the applications of in vitro technologies to enhance yield and productivity of such products. In this study, we investigated the accumulation of biomass and antioxidant secondary metabolites in response to different carbohydrate sources (sucrose, maltose, fructose and glucose) and sucrose concentrations (1, 3, 5, 7 and 9 %). Moreover, the effects of 3 % repeated sucrose feeding (day-12, -18 and -24) were also investigated. The results showed the superiority of disaccharides over monosaccharides for maximum biomass and secondary metabolites accumulation. Comparable profiles for maximum biomass were observed in response to sucrose and maltose and initial sucrose concentrations of 3 and 5 %. Maximum total phenolic and total flavonoid contents were displayed by cultures treated with sucrose and maltose; however, initial sucrose concentrations of 5 and 7 % were optimum for both classes of metabolites, respectively. Following 3 % extra sucrose feeding, cultures fed on day-24 (late-log phase) showed higher biomass, total phenolic and total flavonoid contents as compared to control cultures. Highest antioxidant activity was exhibited by maltose-treated cultures. Moreover, sucrose-treated cultures displayed positive correlation of antioxidant activity with total phenolics and total flavonoids production. This work describes the stimulatory role of disaccharides and sucrose feeding strategy for higher accumulation of phenolics and flavonoids, which could be potentially scaled up to bioreactor level for the bulk production of these metabolites in suspension cultures of A. absinthium.
    63 schema:genre research_article
    64 schema:inLanguage en
    65 schema:isAccessibleForFree false
    66 schema:isPartOf N7fdf73d3547a41dd87a156ad90ffa221
    67 N9e7857859f2e424484f06f5302febfc0
    68 sg:journal.1297453
    69 schema:name Sucrose-enhanced biosynthesis of medicinally important antioxidant secondary metabolites in cell suspension cultures of Artemisia absinthium L.
    70 schema:pagination 1945-1954
    71 schema:productId N7b4990a0970d4edb9eea883dc05b9e93
    72 N934efbfcf0a14220af12a75e9fa251f9
    73 Nb6dcdc522b214e41ab3e7e5a29b23450
    74 Ncf68c52bd2e94e5d8c8c7b864cfe397e
    75 Nff1e5672446d498a944323f54a290e5a
    76 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047837183
    77 https://doi.org/10.1007/s00449-016-1668-8
    78 schema:sdDatePublished 2019-04-11T12:35
    79 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    80 schema:sdPublisher N5d4548cd3dc644cabdc818c10fd4a350
    81 schema:url https://link.springer.com/10.1007%2Fs00449-016-1668-8
    82 sgo:license sg:explorer/license/
    83 sgo:sdDataset articles
    84 rdf:type schema:ScholarlyArticle
    85 N234b770a0e2a442697c5bc0884e363ab schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    86 schema:name Sucrose
    87 rdf:type schema:DefinedTerm
    88 N3a3ce6e0bf2a4965bf2424e8b47e3b25 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    89 schema:name Artemisia absinthium
    90 rdf:type schema:DefinedTerm
    91 N3ebadf893d744ada8af9b2e4ca73ce49 rdf:first sg:person.01214656245.79
    92 rdf:rest N618a1c9729714d78bdb3fccc07443a75
    93 N5d4548cd3dc644cabdc818c10fd4a350 schema:name Springer Nature - SN SciGraph project
    94 rdf:type schema:Organization
    95 N618a1c9729714d78bdb3fccc07443a75 rdf:first sg:person.01240452675.58
    96 rdf:rest Nbbbbae0e7ed7485a8c497f2badb4083a
    97 N67ed9c0ff32b4112a621915b76acd7fe schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    98 schema:name Plant Cells
    99 rdf:type schema:DefinedTerm
    100 N7b4990a0970d4edb9eea883dc05b9e93 schema:name readcube_id
    101 schema:value e3e26504378fb5e2cdb74a3317a4243f469c8883e025c4bb63598771599f8db6
    102 rdf:type schema:PropertyValue
    103 N7fdf73d3547a41dd87a156ad90ffa221 schema:issueNumber 12
    104 rdf:type schema:PublicationIssue
    105 N934efbfcf0a14220af12a75e9fa251f9 schema:name nlm_unique_id
    106 schema:value 101088505
    107 rdf:type schema:PropertyValue
    108 N9e7857859f2e424484f06f5302febfc0 schema:volumeNumber 39
    109 rdf:type schema:PublicationVolume
    110 Na6fe966db41d40fe9b0f56c946ce6e49 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    111 schema:name Antioxidants
    112 rdf:type schema:DefinedTerm
    113 Nb6dcdc522b214e41ab3e7e5a29b23450 schema:name pubmed_id
    114 schema:value 27515537
    115 rdf:type schema:PropertyValue
    116 Nbbbbae0e7ed7485a8c497f2badb4083a rdf:first sg:person.0626435151.00
    117 rdf:rest Ne025873261234c9c9133e89b0cd47b7f
    118 Ncf68c52bd2e94e5d8c8c7b864cfe397e schema:name dimensions_id
    119 schema:value pub.1047837183
    120 rdf:type schema:PropertyValue
    121 Ndf489403e89f43a8ab66191ecca17f95 rdf:first sg:person.01011136722.23
    122 rdf:rest Nef501459771847f08abe9b4bb5feded1
    123 Ne025873261234c9c9133e89b0cd47b7f rdf:first sg:person.01301657501.38
    124 rdf:rest rdf:nil
    125 Nef501459771847f08abe9b4bb5feded1 rdf:first sg:person.0605500545.25
    126 rdf:rest N3ebadf893d744ada8af9b2e4ca73ce49
    127 Nf2d0980646a245329322bae519ee65bb schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    128 schema:name Flavonoids
    129 rdf:type schema:DefinedTerm
    130 Nff1e5672446d498a944323f54a290e5a schema:name doi
    131 schema:value 10.1007/s00449-016-1668-8
    132 rdf:type schema:PropertyValue
    133 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
    134 schema:name Medical and Health Sciences
    135 rdf:type schema:DefinedTerm
    136 anzsrc-for:1115 schema:inDefinedTermSet anzsrc-for:
    137 schema:name Pharmacology and Pharmaceutical Sciences
    138 rdf:type schema:DefinedTerm
    139 sg:journal.1297453 schema:issn 1615-7591
    140 1615-7605
    141 schema:name Bioprocess and Biosystems Engineering
    142 rdf:type schema:Periodical
    143 sg:person.01011136722.23 schema:affiliation https://www.grid.ac/institutes/grid.449683.4
    144 schema:familyName Ali
    145 schema:givenName Mohammad
    146 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01011136722.23
    147 rdf:type schema:Person
    148 sg:person.01214656245.79 schema:affiliation https://www.grid.ac/institutes/grid.449683.4
    149 schema:familyName Ahmad
    150 schema:givenName Nisar
    151 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01214656245.79
    152 rdf:type schema:Person
    153 sg:person.01240452675.58 schema:affiliation https://www.grid.ac/institutes/grid.449683.4
    154 schema:familyName Ali
    155 schema:givenName Syed Shujait
    156 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01240452675.58
    157 rdf:type schema:Person
    158 sg:person.01301657501.38 schema:affiliation https://www.grid.ac/institutes/grid.15276.37
    159 schema:familyName Ali
    160 schema:givenName Gul Shad
    161 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01301657501.38
    162 rdf:type schema:Person
    163 sg:person.0605500545.25 schema:affiliation https://www.grid.ac/institutes/grid.412621.2
    164 schema:familyName Abbasi
    165 schema:givenName Bilal Haider
    166 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0605500545.25
    167 rdf:type schema:Person
    168 sg:person.0626435151.00 schema:affiliation https://www.grid.ac/institutes/grid.449683.4
    169 schema:familyName Ali
    170 schema:givenName Shahid
    171 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0626435151.00
    172 rdf:type schema:Person
    173 sg:pub.10.1007/bf00034492 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013226533
    174 https://doi.org/10.1007/bf00034492
    175 rdf:type schema:CreativeWork
    176 sg:pub.10.1007/bf00134204 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050375018
    177 https://doi.org/10.1007/bf00134204
    178 rdf:type schema:CreativeWork
    179 sg:pub.10.1007/bf00194280 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016153691
    180 https://doi.org/10.1007/bf00194280
    181 rdf:type schema:CreativeWork
    182 sg:pub.10.1007/bf03030532 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020516142
    183 https://doi.org/10.1007/bf03030532
    184 rdf:type schema:CreativeWork
    185 sg:pub.10.1007/s00299-004-0837-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038316092
    186 https://doi.org/10.1007/s00299-004-0837-4
    187 rdf:type schema:CreativeWork
    188 sg:pub.10.1007/s00299-006-0295-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024385831
    189 https://doi.org/10.1007/s00299-006-0295-2
    190 rdf:type schema:CreativeWork
    191 sg:pub.10.1007/s11033-012-1569-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043617465
    192 https://doi.org/10.1007/s11033-012-1569-0
    193 rdf:type schema:CreativeWork
    194 sg:pub.10.1007/s11240-010-9692-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1021931568
    195 https://doi.org/10.1007/s11240-010-9692-x
    196 rdf:type schema:CreativeWork
    197 sg:pub.10.1007/s11240-010-9747-z schema:sameAs https://app.dimensions.ai/details/publication/pub.1039213008
    198 https://doi.org/10.1007/s11240-010-9747-z
    199 rdf:type schema:CreativeWork
    200 sg:pub.10.1007/s11240-013-0325-z schema:sameAs https://app.dimensions.ai/details/publication/pub.1037782588
    201 https://doi.org/10.1007/s11240-013-0325-z
    202 rdf:type schema:CreativeWork
    203 sg:pub.10.1007/s11240-014-0666-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032588869
    204 https://doi.org/10.1007/s11240-014-0666-2
    205 rdf:type schema:CreativeWork
    206 sg:pub.10.1007/s11240-015-0915-z schema:sameAs https://app.dimensions.ai/details/publication/pub.1025376396
    207 https://doi.org/10.1007/s11240-015-0915-z
    208 rdf:type schema:CreativeWork
    209 sg:pub.10.1007/s11627-006-9001-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1036875974
    210 https://doi.org/10.1007/s11627-006-9001-x
    211 rdf:type schema:CreativeWork
    212 sg:pub.10.1007/s11738-011-0837-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024570303
    213 https://doi.org/10.1007/s11738-011-0837-2
    214 rdf:type schema:CreativeWork
    215 sg:pub.10.1007/s11738-012-1011-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031621848
    216 https://doi.org/10.1007/s11738-012-1011-1
    217 rdf:type schema:CreativeWork
    218 sg:pub.10.1007/s11816-012-0270-z schema:sameAs https://app.dimensions.ai/details/publication/pub.1025329712
    219 https://doi.org/10.1007/s11816-012-0270-z
    220 rdf:type schema:CreativeWork
    221 sg:pub.10.1023/a:1016356123367 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052147173
    222 https://doi.org/10.1023/a:1016356123367
    223 rdf:type schema:CreativeWork
    224 sg:pub.10.1023/a:1018355002041 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048997245
    225 https://doi.org/10.1023/a:1018355002041
    226 rdf:type schema:CreativeWork
    227 sg:pub.10.1023/a:1026472527872 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026068177
    228 https://doi.org/10.1023/a:1026472527872
    229 rdf:type schema:CreativeWork
    230 sg:pub.10.1023/a:1026506426420 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002502012
    231 https://doi.org/10.1023/a:1026506426420
    232 rdf:type schema:CreativeWork
    233 sg:pub.10.1038/sj.jim.2900600 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036235223
    234 https://doi.org/10.1038/sj.jim.2900600
    235 rdf:type schema:CreativeWork
    236 sg:pub.10.1186/1752-153x-6-97 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017722208
    237 https://doi.org/10.1186/1752-153x-6-97
    238 rdf:type schema:CreativeWork
    239 https://app.dimensions.ai/details/publication/pub.1078417735 schema:CreativeWork
    240 https://app.dimensions.ai/details/publication/pub.1078456478 schema:CreativeWork
    241 https://app.dimensions.ai/details/publication/pub.1078882817 schema:CreativeWork
    242 https://doi.org/10.1002/jsfa.1950 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023024264
    243 rdf:type schema:CreativeWork
    244 https://doi.org/10.1016/0141-0229(95)00033-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1008243291
    245 rdf:type schema:CreativeWork
    246 https://doi.org/10.1016/0168-1656(96)01560-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1034322193
    247 rdf:type schema:CreativeWork
    248 https://doi.org/10.1016/j.biortech.2008.09.028 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011027140
    249 rdf:type schema:CreativeWork
    250 https://doi.org/10.1016/j.biortech.2010.03.078 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018528849
    251 rdf:type schema:CreativeWork
    252 https://doi.org/10.1016/j.indcrop.2013.05.033 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041123082
    253 rdf:type schema:CreativeWork
    254 https://doi.org/10.1016/j.jphotobiol.2014.08.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045799107
    255 rdf:type schema:CreativeWork
    256 https://doi.org/10.1016/j.phymed.2009.10.013 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044823483
    257 rdf:type schema:CreativeWork
    258 https://doi.org/10.1016/j.phytochem.2008.02.014 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032386991
    259 rdf:type schema:CreativeWork
    260 https://doi.org/10.1016/j.plaphy.2005.02.011 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029608101
    261 rdf:type schema:CreativeWork
    262 https://doi.org/10.1016/j.procbio.2005.09.005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003777905
    263 rdf:type schema:CreativeWork
    264 https://doi.org/10.1016/j.procbio.2006.09.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011175371
    265 rdf:type schema:CreativeWork
    266 https://doi.org/10.1016/s0032-9592(99)00094-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048267696
    267 rdf:type schema:CreativeWork
    268 https://doi.org/10.1021/bp0001359 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036220535
    269 rdf:type schema:CreativeWork
    270 https://doi.org/10.1021/jf9801973 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055930243
    271 rdf:type schema:CreativeWork
    272 https://doi.org/10.1021/jm010359d schema:sameAs https://app.dimensions.ai/details/publication/pub.1055946658
    273 rdf:type schema:CreativeWork
    274 https://doi.org/10.1055/s-2003-37714 schema:sameAs https://app.dimensions.ai/details/publication/pub.1057420319
    275 rdf:type schema:CreativeWork
    276 https://doi.org/10.1104/pp.105.072579 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018120339
    277 rdf:type schema:CreativeWork
    278 https://doi.org/10.1105/tpc.010455 schema:sameAs https://app.dimensions.ai/details/publication/pub.1075064431
    279 rdf:type schema:CreativeWork
    280 https://doi.org/10.1111/j.1399-3054.1962.tb08052.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1023703429
    281 rdf:type schema:CreativeWork
    282 https://doi.org/10.1146/annurev.arplant.47.1.509 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020396519
    283 rdf:type schema:CreativeWork
    284 https://doi.org/10.1146/annurev.arplant.57.032905.105441 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044874917
    285 rdf:type schema:CreativeWork
    286 https://doi.org/10.1177/1082013211399495 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040875118
    287 rdf:type schema:CreativeWork
    288 https://doi.org/10.1515/znc-2009-1-212 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048668239
    289 rdf:type schema:CreativeWork
    290 https://doi.org/10.18388/abp.2014_1922 schema:sameAs https://app.dimensions.ai/details/publication/pub.1078882817
    291 rdf:type schema:CreativeWork
    292 https://doi.org/10.5897/ajpp12.945 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007862401
    293 rdf:type schema:CreativeWork
    294 https://www.grid.ac/institutes/grid.15276.37 schema:alternateName University of Florida
    295 schema:name Mid-Florida Research and Education Center and Department of Plant Pathology, University of Florida/Institute of Food and Agricultural Sciences, 2725 Binion Rd, 32703, Apopka, FL, USA
    296 rdf:type schema:Organization
    297 https://www.grid.ac/institutes/grid.412621.2 schema:alternateName Quaid-i-Azam University
    298 schema:name Department of Biotechnology, Faculty of Biological Sciences, Quaid-i-Azam University, 45320, Islamabad, Pakistan
    299 rdf:type schema:Organization
    300 https://www.grid.ac/institutes/grid.449683.4 schema:alternateName University of Swat
    301 schema:name Center for Biotechnology and Microbiology, University of Swat, 19200, Swat, Pakistan
    302 Department of Biotechnology, Faculty of Biological Sciences, Quaid-i-Azam University, 45320, Islamabad, Pakistan
    303 rdf:type schema:Organization
     




    Preview window. Press ESC to close (or click here)


    ...