Comparative repair capacity of knee osteochondral defects using regenerated silk fiber scaffolds and fibrin glue with/without autologous chondrocytes during 36 ... View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2016-06

AUTHORS

Somaieh Kazemnejad, Manijeh Khanmohammadi, Sahba Mobini, Masoud Taghizadeh-Jahed, Sayeh Khanjani, Shaghayegh Arasteh, Hannaneh Golshahi, Giti Torkaman, Roya Ravanbod, Hamed Heidari-Vala, Ali Moshiri, Mohammad-Naghi Tahmasebi, Mohammad-Mehdi Akhondi

ABSTRACT

The reconstruction capability of osteochondral (OCD) defects using silk-based scaffolds has been demonstrated in a few studies. However, improvement in the mechanical properties of natural scaffolds is still challengeable. Here, we investigate the in vivo repair capacity of OCD defects using a novel Bombyx mori silk-based composite scaffold with great mechanical properties and porosity during 36 weeks. After evaluation of the in vivo biocompatibility and degradation rate of these scaffolds, we examined the effectiveness of these fabricated scaffolds accompanied with/without autologous chondrocytes in the repair of OCD lesions of rabbit knees after 12 and 36 weeks. Moreover, the efficiency of these scaffolds was compared with fibrin glue (FG) as a natural carrier of chondrocytes using parallel clinical, histopathological and mechanical examinations. The data on subcutaneous implantation in mice showed that the designed scaffolds have a suitable in vivo degradation rate and regenerative capacity. The repair ability of chondrocyte-seeded scaffolds was typically higher than the scaffolds alone. After 36 weeks of implantation, most parts of the defects reconstructed by chondrocytes-seeded silk scaffolds (SFC) were hyaline-like cartilage. However, spontaneous healing and filling with a scaffold alone did not eventuate in typical repair. We could not find significant differences between quantitative histopathological and mechanical data of SFC and FGC. The fabricated constructs consisting of regenerated silk fiber scaffolds and chondrocytes are safe and suitable for in vivo repair of OCD defects and promising for future clinical trial studies. More... »

PAGES

559-572

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00441-015-2355-9

DOI

http://dx.doi.org/10.1007/s00441-015-2355-9

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1032028622

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/26822846


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Biomechanical Phenomena", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cartilage, Articular", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Chondrocytes", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Collagen Type II", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Disease Models, Animal", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Fibrin Tissue Adhesive", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Hindlimb", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Immunohistochemistry", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mice, Inbred C57BL", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Prosthesis Implantation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Rabbits", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Regeneration", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Silk", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Subcutaneous Tissue", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Tissue Scaffolds", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Transplantation, Autologous", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Wound Healing", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Academic Center for Education, Culture and Research", 
          "id": "https://www.grid.ac/institutes/grid.417689.5", 
          "name": [
            "Reproductive Biotechnology Research Center, Avicenna Research Institute, Academic Center for Education, Culture and Research (ACECR), P.O. Box: 19615-1177, Tehran, Iran"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kazemnejad", 
        "givenName": "Somaieh", 
        "id": "sg:person.0641532123.05", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0641532123.05"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Academic Center for Education, Culture and Research", 
          "id": "https://www.grid.ac/institutes/grid.417689.5", 
          "name": [
            "Reproductive Biotechnology Research Center, Avicenna Research Institute, Academic Center for Education, Culture and Research (ACECR), P.O. Box: 19615-1177, Tehran, Iran"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Khanmohammadi", 
        "givenName": "Manijeh", 
        "id": "sg:person.01235511471.73", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01235511471.73"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Academic Center for Education, Culture and Research", 
          "id": "https://www.grid.ac/institutes/grid.417689.5", 
          "name": [
            "Reproductive Biotechnology Research Center, Avicenna Research Institute, Academic Center for Education, Culture and Research (ACECR), P.O. Box: 19615-1177, Tehran, Iran"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Mobini", 
        "givenName": "Sahba", 
        "id": "sg:person.01244541061.29", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01244541061.29"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Academic Center for Education, Culture and Research", 
          "id": "https://www.grid.ac/institutes/grid.417689.5", 
          "name": [
            "Reproductive Biotechnology Research Center, Avicenna Research Institute, Academic Center for Education, Culture and Research (ACECR), P.O. Box: 19615-1177, Tehran, Iran"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Taghizadeh-Jahed", 
        "givenName": "Masoud", 
        "id": "sg:person.01230426730.15", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01230426730.15"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Academic Center for Education, Culture and Research", 
          "id": "https://www.grid.ac/institutes/grid.417689.5", 
          "name": [
            "Reproductive Biotechnology Research Center, Avicenna Research Institute, Academic Center for Education, Culture and Research (ACECR), P.O. Box: 19615-1177, Tehran, Iran"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Khanjani", 
        "givenName": "Sayeh", 
        "id": "sg:person.01157671667.76", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01157671667.76"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Academic Center for Education, Culture and Research", 
          "id": "https://www.grid.ac/institutes/grid.417689.5", 
          "name": [
            "Reproductive Biotechnology Research Center, Avicenna Research Institute, Academic Center for Education, Culture and Research (ACECR), P.O. Box: 19615-1177, Tehran, Iran"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Arasteh", 
        "givenName": "Shaghayegh", 
        "id": "sg:person.01026002725.63", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01026002725.63"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Tehran", 
          "id": "https://www.grid.ac/institutes/grid.46072.37", 
          "name": [
            "Department of Pathology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Golshahi", 
        "givenName": "Hannaneh", 
        "id": "sg:person.01036167467.17", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01036167467.17"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Tarbiat Modares University", 
          "id": "https://www.grid.ac/institutes/grid.412266.5", 
          "name": [
            "Department of Physical Therapy, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Torkaman", 
        "givenName": "Giti", 
        "id": "sg:person.0711321331.20", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0711321331.20"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Tarbiat Modares University", 
          "id": "https://www.grid.ac/institutes/grid.412266.5", 
          "name": [
            "Department of Physical Therapy, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ravanbod", 
        "givenName": "Roya", 
        "id": "sg:person.0627706332.00", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0627706332.00"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Academic Center for Education, Culture and Research", 
          "id": "https://www.grid.ac/institutes/grid.417689.5", 
          "name": [
            "Reproductive Biotechnology Research Center, Avicenna Research Institute, Academic Center for Education, Culture and Research (ACECR), P.O. Box: 19615-1177, Tehran, Iran"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Heidari-Vala", 
        "givenName": "Hamed", 
        "id": "sg:person.0700447670.58", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0700447670.58"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Iran University of Medical Sciences", 
          "id": "https://www.grid.ac/institutes/grid.411746.1", 
          "name": [
            "Razi Drug Research Center, Iran University of Medical Sciences, Tehran, Iran"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Moshiri", 
        "givenName": "Ali", 
        "id": "sg:person.01350616172.00", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01350616172.00"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Tehran University of Medical Sciences", 
          "id": "https://www.grid.ac/institutes/grid.411705.6", 
          "name": [
            "Orthopedic Department, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Tahmasebi", 
        "givenName": "Mohammad-Naghi", 
        "id": "sg:person.0751705432.41", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0751705432.41"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Academic Center for Education, Culture and Research", 
          "id": "https://www.grid.ac/institutes/grid.417689.5", 
          "name": [
            "Reproductive Biotechnology Research Center, Avicenna Research Institute, Academic Center for Education, Culture and Research (ACECR), P.O. Box: 19615-1177, Tehran, Iran"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Akhondi", 
        "givenName": "Mohammad-Mehdi", 
        "id": "sg:person.015610621747.52", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015610621747.52"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1053/joca.1997.0092", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001429888"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.1188936", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002257404"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/10_013", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004128903", 
          "https://doi.org/10.1007/10_013"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1525-1594.2005.00137.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005255291"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1525-1594.2005.00137.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005255291"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1177/1947603510366027", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009012733"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1177/1947603510366027", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009012733"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.actbio.2014.10.021", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010350354"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/7651_2013_9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014139500", 
          "https://doi.org/10.1007/7651_2013_9"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.biotechadv.2012.11.004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015536301"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.biomaterials.2012.06.058", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015543267"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0142-9612(97)00190-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017618751"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.biomaterials.2013.04.055", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017702671"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.biomaterials.2008.05.002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018314625"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00006534-199906000-00001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018333273"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00006534-199906000-00001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018333273"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jbiomech.2006.03.008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019531333"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1053/joca.2001.0438", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020080860"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/jbm.b.31571", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021684323"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/jbm.b.31571", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021684323"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.biomaterials.2012.09.017", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023007257"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.biomaterials.2004.01.066", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024139372"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00167-012-1891-z", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024994157", 
          "https://doi.org/10.1007/s00167-012-1891-z"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nbt0794-689", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026197737", 
          "https://doi.org/10.1038/nbt0794-689"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/jbm.a.34537", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029473293"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.biomaterials.2009.01.016", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030394320"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nmat1822", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034972931", 
          "https://doi.org/10.1038/nmat1822"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nmat1822", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034972931", 
          "https://doi.org/10.1038/nmat1822"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.progpolymsci.2007.05.013", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039308756"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0142-9612(96)00117-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040067754"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jbiosc.2014.05.001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040388276"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.biomaterials.2006.07.008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042455575"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1177/0363546503259616", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043483314"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1177/0363546503259616", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043483314"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.addr.2012.09.043", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045806998"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.biomaterials.2004.09.020", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045808018"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0080004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046664664"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10856-013-4944-z", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048733090", 
          "https://doi.org/10.1007/s10856-013-4944-z"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0142-9612(02)00353-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048889849"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0142-9612(00)00121-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048945344"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00167-008-0663-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049889875", 
          "https://doi.org/10.1007/s00167-008-0663-2"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00167-008-0663-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049889875", 
          "https://doi.org/10.1007/s00167-008-0663-2"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/sap.0b013e3181d6e38b", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051601989"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/sap.0b013e3181d6e38b", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051601989"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/sap.0b013e3181d6e38b", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051601989"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1089/ten.1998.4.429", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1059313133"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1089/ten.2006.0181", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1059313561"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2106/jbjs.k.00748", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1068902588"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2106/jbjs.k.00748", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1068902588"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2106/jbjs.k.00748", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1068902588"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3791/4423", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1071423498"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.4161/org.6116", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1072306931"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1089/cell.2012.0002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1078597127"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2016-06", 
    "datePublishedReg": "2016-06-01", 
    "description": "The reconstruction capability of osteochondral (OCD) defects using silk-based scaffolds has been demonstrated in a few studies. However, improvement in the mechanical properties of natural scaffolds is still challengeable. Here, we investigate the in vivo repair capacity of OCD defects using a novel Bombyx mori silk-based composite scaffold with great mechanical properties and porosity during 36\u00a0weeks. After evaluation of the in vivo biocompatibility and degradation rate of these scaffolds, we examined the effectiveness of these fabricated scaffolds accompanied with/without autologous chondrocytes in the repair of OCD lesions of rabbit knees after 12 and 36\u00a0weeks. Moreover, the efficiency of these scaffolds was compared with fibrin glue (FG) as a natural carrier of chondrocytes using parallel clinical, histopathological and mechanical examinations. The data on subcutaneous implantation in mice showed that the designed scaffolds have a suitable in vivo degradation rate and regenerative capacity. The repair ability of chondrocyte-seeded scaffolds was typically higher than the scaffolds alone. After 36\u00a0weeks of implantation, most parts of the defects reconstructed by chondrocytes-seeded silk scaffolds (SFC) were hyaline-like cartilage. However, spontaneous healing and filling with a scaffold alone did not eventuate in typical repair. We could not find significant differences between quantitative histopathological and mechanical data of SFC and FGC. The fabricated constructs consisting of regenerated silk fiber scaffolds and chondrocytes are safe and suitable for in vivo repair of OCD defects and promising for future clinical trial studies. ", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s00441-015-2355-9", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1019675", 
        "issn": [
          "0302-766X", 
          "1432-0878"
        ], 
        "name": "Cell and Tissue Research", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "3", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "364"
      }
    ], 
    "name": "Comparative repair capacity of knee osteochondral defects using regenerated silk fiber scaffolds and fibrin glue with/without autologous chondrocytes during 36 weeks in rabbit model", 
    "pagination": "559-572", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "989443645e082a42ec04dbe995535bb145999c5d2f6495a6c1fff1f65e2cc7e7"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "26822846"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "0417625"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s00441-015-2355-9"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1032028622"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s00441-015-2355-9", 
      "https://app.dimensions.ai/details/publication/pub.1032028622"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T10:39", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000349_0000000349/records_113679_00000001.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://link.springer.com/10.1007%2Fs00441-015-2355-9"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00441-015-2355-9'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00441-015-2355-9'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00441-015-2355-9'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00441-015-2355-9'


 

This table displays all metadata directly associated to this object as RDF triples.

374 TRIPLES      21 PREDICATES      90 URIs      40 LITERALS      28 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s00441-015-2355-9 schema:about N00aea97d84b048788d5e365b553ba289
2 N1008e12434c248afac4821f1711fc4e1
3 N114be6e0f5b24f3695c7f8097715dea3
4 N2137eafacfbd490c891c6ecc1e789308
5 N27f3c261c6014ccd9a8797d21fe5138e
6 N2e7ea03ef79c4ca8bed2cb8bb72a1d29
7 N35c77bcf14144c7eb620e4dc73adaec8
8 N40ebdaa769b54230850ff61393a25417
9 N5c06425a3bb64419a0668fb8a9f14369
10 N6b1724ab8d2c46c9a8e6aa0347d6856a
11 N766dd4125b66419280e4ad6deb26dafc
12 N881ba6e0432b43d2bc8fee875c43aa45
13 Na2f6c531f25f457a9251222a79e81c07
14 Naca2d858bc8a46a98f47032adc92e3dd
15 Nc520bd5bc785466cb3773c3c0255b648
16 Nc598b2fdfa4644a489872133bfa68f2e
17 Ndbde6216c6a04c448cf572d084a2206f
18 Ne9c667e37dd74ba28347bca010211c5d
19 Nfb558d1b0b20416085a25606cdf5533f
20 anzsrc-for:11
21 anzsrc-for:1103
22 schema:author N34e6c2ae6e8b4f80823956c7ed0bdf1c
23 schema:citation sg:pub.10.1007/10_013
24 sg:pub.10.1007/7651_2013_9
25 sg:pub.10.1007/s00167-008-0663-2
26 sg:pub.10.1007/s00167-012-1891-z
27 sg:pub.10.1007/s10856-013-4944-z
28 sg:pub.10.1038/nbt0794-689
29 sg:pub.10.1038/nmat1822
30 https://doi.org/10.1002/jbm.a.34537
31 https://doi.org/10.1002/jbm.b.31571
32 https://doi.org/10.1016/j.actbio.2014.10.021
33 https://doi.org/10.1016/j.addr.2012.09.043
34 https://doi.org/10.1016/j.biomaterials.2004.01.066
35 https://doi.org/10.1016/j.biomaterials.2004.09.020
36 https://doi.org/10.1016/j.biomaterials.2006.07.008
37 https://doi.org/10.1016/j.biomaterials.2008.05.002
38 https://doi.org/10.1016/j.biomaterials.2009.01.016
39 https://doi.org/10.1016/j.biomaterials.2012.06.058
40 https://doi.org/10.1016/j.biomaterials.2012.09.017
41 https://doi.org/10.1016/j.biomaterials.2013.04.055
42 https://doi.org/10.1016/j.biotechadv.2012.11.004
43 https://doi.org/10.1016/j.jbiomech.2006.03.008
44 https://doi.org/10.1016/j.jbiosc.2014.05.001
45 https://doi.org/10.1016/j.progpolymsci.2007.05.013
46 https://doi.org/10.1016/s0142-9612(00)00121-6
47 https://doi.org/10.1016/s0142-9612(02)00353-8
48 https://doi.org/10.1016/s0142-9612(96)00117-2
49 https://doi.org/10.1016/s0142-9612(97)00190-7
50 https://doi.org/10.1053/joca.1997.0092
51 https://doi.org/10.1053/joca.2001.0438
52 https://doi.org/10.1089/cell.2012.0002
53 https://doi.org/10.1089/ten.1998.4.429
54 https://doi.org/10.1089/ten.2006.0181
55 https://doi.org/10.1097/00006534-199906000-00001
56 https://doi.org/10.1097/sap.0b013e3181d6e38b
57 https://doi.org/10.1111/j.1525-1594.2005.00137.x
58 https://doi.org/10.1126/science.1188936
59 https://doi.org/10.1177/0363546503259616
60 https://doi.org/10.1177/1947603510366027
61 https://doi.org/10.1371/journal.pone.0080004
62 https://doi.org/10.2106/jbjs.k.00748
63 https://doi.org/10.3791/4423
64 https://doi.org/10.4161/org.6116
65 schema:datePublished 2016-06
66 schema:datePublishedReg 2016-06-01
67 schema:description The reconstruction capability of osteochondral (OCD) defects using silk-based scaffolds has been demonstrated in a few studies. However, improvement in the mechanical properties of natural scaffolds is still challengeable. Here, we investigate the in vivo repair capacity of OCD defects using a novel Bombyx mori silk-based composite scaffold with great mechanical properties and porosity during 36 weeks. After evaluation of the in vivo biocompatibility and degradation rate of these scaffolds, we examined the effectiveness of these fabricated scaffolds accompanied with/without autologous chondrocytes in the repair of OCD lesions of rabbit knees after 12 and 36 weeks. Moreover, the efficiency of these scaffolds was compared with fibrin glue (FG) as a natural carrier of chondrocytes using parallel clinical, histopathological and mechanical examinations. The data on subcutaneous implantation in mice showed that the designed scaffolds have a suitable in vivo degradation rate and regenerative capacity. The repair ability of chondrocyte-seeded scaffolds was typically higher than the scaffolds alone. After 36 weeks of implantation, most parts of the defects reconstructed by chondrocytes-seeded silk scaffolds (SFC) were hyaline-like cartilage. However, spontaneous healing and filling with a scaffold alone did not eventuate in typical repair. We could not find significant differences between quantitative histopathological and mechanical data of SFC and FGC. The fabricated constructs consisting of regenerated silk fiber scaffolds and chondrocytes are safe and suitable for in vivo repair of OCD defects and promising for future clinical trial studies.
68 schema:genre research_article
69 schema:inLanguage en
70 schema:isAccessibleForFree false
71 schema:isPartOf Nc95c5812aa4741eda458d700464c9d51
72 Nf1ad2eb5f1c34495a6aebb193dda6bca
73 sg:journal.1019675
74 schema:name Comparative repair capacity of knee osteochondral defects using regenerated silk fiber scaffolds and fibrin glue with/without autologous chondrocytes during 36 weeks in rabbit model
75 schema:pagination 559-572
76 schema:productId N07c390ae36704f6099e47891ebe65c4f
77 N27911837865e44ce9d9a942852747968
78 N8c0dc49b17b6423bbbfe2a023363140a
79 Nf6a89627ea474446a97fa99d73c9d2ba
80 Nf9a106761f75422995c4dade7a63956c
81 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032028622
82 https://doi.org/10.1007/s00441-015-2355-9
83 schema:sdDatePublished 2019-04-11T10:39
84 schema:sdLicense https://scigraph.springernature.com/explorer/license/
85 schema:sdPublisher N19de401f657d4dc6be93fa3c2c84f953
86 schema:url https://link.springer.com/10.1007%2Fs00441-015-2355-9
87 sgo:license sg:explorer/license/
88 sgo:sdDataset articles
89 rdf:type schema:ScholarlyArticle
90 N004e9c8db48e48cdb6d2e9854909581d rdf:first sg:person.0751705432.41
91 rdf:rest Necad4ffbaede4aecb33dbf3e83e633e3
92 N00aea97d84b048788d5e365b553ba289 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
93 schema:name Wound Healing
94 rdf:type schema:DefinedTerm
95 N07c390ae36704f6099e47891ebe65c4f schema:name nlm_unique_id
96 schema:value 0417625
97 rdf:type schema:PropertyValue
98 N1008e12434c248afac4821f1711fc4e1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
99 schema:name Cartilage, Articular
100 rdf:type schema:DefinedTerm
101 N114be6e0f5b24f3695c7f8097715dea3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
102 schema:name Male
103 rdf:type schema:DefinedTerm
104 N19de401f657d4dc6be93fa3c2c84f953 schema:name Springer Nature - SN SciGraph project
105 rdf:type schema:Organization
106 N2137eafacfbd490c891c6ecc1e789308 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
107 schema:name Silk
108 rdf:type schema:DefinedTerm
109 N27911837865e44ce9d9a942852747968 schema:name dimensions_id
110 schema:value pub.1032028622
111 rdf:type schema:PropertyValue
112 N27f3c261c6014ccd9a8797d21fe5138e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
113 schema:name Fibrin Tissue Adhesive
114 rdf:type schema:DefinedTerm
115 N2e7ea03ef79c4ca8bed2cb8bb72a1d29 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
116 schema:name Transplantation, Autologous
117 rdf:type schema:DefinedTerm
118 N34e6c2ae6e8b4f80823956c7ed0bdf1c rdf:first sg:person.0641532123.05
119 rdf:rest N40a654f6d82945258007c42480fdcde8
120 N35c77bcf14144c7eb620e4dc73adaec8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
121 schema:name Biomechanical Phenomena
122 rdf:type schema:DefinedTerm
123 N40a654f6d82945258007c42480fdcde8 rdf:first sg:person.01235511471.73
124 rdf:rest Nf1c56cfb83be47e9b384a108517d126c
125 N40ebdaa769b54230850ff61393a25417 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
126 schema:name Immunohistochemistry
127 rdf:type schema:DefinedTerm
128 N56017121de5747baa06b75deb8550c2d rdf:first sg:person.01350616172.00
129 rdf:rest N004e9c8db48e48cdb6d2e9854909581d
130 N5c06425a3bb64419a0668fb8a9f14369 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
131 schema:name Chondrocytes
132 rdf:type schema:DefinedTerm
133 N6b1724ab8d2c46c9a8e6aa0347d6856a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
134 schema:name Collagen Type II
135 rdf:type schema:DefinedTerm
136 N76393c144e084b278d14ad696a5b86a1 rdf:first sg:person.0711321331.20
137 rdf:rest Ne8a88abbb9d943869bc82d5fdd855fc8
138 N766dd4125b66419280e4ad6deb26dafc schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
139 schema:name Tissue Scaffolds
140 rdf:type schema:DefinedTerm
141 N7b89f1d62449456bb414a1d1b34ff3d1 rdf:first sg:person.01036167467.17
142 rdf:rest N76393c144e084b278d14ad696a5b86a1
143 N7ca952943d514387b7e1ad72362a1d66 rdf:first sg:person.01026002725.63
144 rdf:rest N7b89f1d62449456bb414a1d1b34ff3d1
145 N881ba6e0432b43d2bc8fee875c43aa45 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
146 schema:name Disease Models, Animal
147 rdf:type schema:DefinedTerm
148 N8c0dc49b17b6423bbbfe2a023363140a schema:name readcube_id
149 schema:value 989443645e082a42ec04dbe995535bb145999c5d2f6495a6c1fff1f65e2cc7e7
150 rdf:type schema:PropertyValue
151 N8da4c5e832244729b094fb7d983eaa7e rdf:first sg:person.01157671667.76
152 rdf:rest N7ca952943d514387b7e1ad72362a1d66
153 N8e77fe3d6ff3452ba064f950eed1a10a rdf:first sg:person.0700447670.58
154 rdf:rest N56017121de5747baa06b75deb8550c2d
155 Na2f6c531f25f457a9251222a79e81c07 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
156 schema:name Hindlimb
157 rdf:type schema:DefinedTerm
158 Naca2d858bc8a46a98f47032adc92e3dd schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
159 schema:name Subcutaneous Tissue
160 rdf:type schema:DefinedTerm
161 Nc520bd5bc785466cb3773c3c0255b648 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
162 schema:name Animals
163 rdf:type schema:DefinedTerm
164 Nc598b2fdfa4644a489872133bfa68f2e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
165 schema:name Regeneration
166 rdf:type schema:DefinedTerm
167 Nc95c5812aa4741eda458d700464c9d51 schema:volumeNumber 364
168 rdf:type schema:PublicationVolume
169 Ndbde6216c6a04c448cf572d084a2206f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
170 schema:name Rabbits
171 rdf:type schema:DefinedTerm
172 Ne401177146ac42019d27afc57c4115e4 rdf:first sg:person.01230426730.15
173 rdf:rest N8da4c5e832244729b094fb7d983eaa7e
174 Ne8a88abbb9d943869bc82d5fdd855fc8 rdf:first sg:person.0627706332.00
175 rdf:rest N8e77fe3d6ff3452ba064f950eed1a10a
176 Ne9c667e37dd74ba28347bca010211c5d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
177 schema:name Mice, Inbred C57BL
178 rdf:type schema:DefinedTerm
179 Necad4ffbaede4aecb33dbf3e83e633e3 rdf:first sg:person.015610621747.52
180 rdf:rest rdf:nil
181 Nf1ad2eb5f1c34495a6aebb193dda6bca schema:issueNumber 3
182 rdf:type schema:PublicationIssue
183 Nf1c56cfb83be47e9b384a108517d126c rdf:first sg:person.01244541061.29
184 rdf:rest Ne401177146ac42019d27afc57c4115e4
185 Nf6a89627ea474446a97fa99d73c9d2ba schema:name pubmed_id
186 schema:value 26822846
187 rdf:type schema:PropertyValue
188 Nf9a106761f75422995c4dade7a63956c schema:name doi
189 schema:value 10.1007/s00441-015-2355-9
190 rdf:type schema:PropertyValue
191 Nfb558d1b0b20416085a25606cdf5533f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
192 schema:name Prosthesis Implantation
193 rdf:type schema:DefinedTerm
194 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
195 schema:name Medical and Health Sciences
196 rdf:type schema:DefinedTerm
197 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
198 schema:name Clinical Sciences
199 rdf:type schema:DefinedTerm
200 sg:journal.1019675 schema:issn 0302-766X
201 1432-0878
202 schema:name Cell and Tissue Research
203 rdf:type schema:Periodical
204 sg:person.01026002725.63 schema:affiliation https://www.grid.ac/institutes/grid.417689.5
205 schema:familyName Arasteh
206 schema:givenName Shaghayegh
207 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01026002725.63
208 rdf:type schema:Person
209 sg:person.01036167467.17 schema:affiliation https://www.grid.ac/institutes/grid.46072.37
210 schema:familyName Golshahi
211 schema:givenName Hannaneh
212 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01036167467.17
213 rdf:type schema:Person
214 sg:person.01157671667.76 schema:affiliation https://www.grid.ac/institutes/grid.417689.5
215 schema:familyName Khanjani
216 schema:givenName Sayeh
217 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01157671667.76
218 rdf:type schema:Person
219 sg:person.01230426730.15 schema:affiliation https://www.grid.ac/institutes/grid.417689.5
220 schema:familyName Taghizadeh-Jahed
221 schema:givenName Masoud
222 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01230426730.15
223 rdf:type schema:Person
224 sg:person.01235511471.73 schema:affiliation https://www.grid.ac/institutes/grid.417689.5
225 schema:familyName Khanmohammadi
226 schema:givenName Manijeh
227 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01235511471.73
228 rdf:type schema:Person
229 sg:person.01244541061.29 schema:affiliation https://www.grid.ac/institutes/grid.417689.5
230 schema:familyName Mobini
231 schema:givenName Sahba
232 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01244541061.29
233 rdf:type schema:Person
234 sg:person.01350616172.00 schema:affiliation https://www.grid.ac/institutes/grid.411746.1
235 schema:familyName Moshiri
236 schema:givenName Ali
237 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01350616172.00
238 rdf:type schema:Person
239 sg:person.015610621747.52 schema:affiliation https://www.grid.ac/institutes/grid.417689.5
240 schema:familyName Akhondi
241 schema:givenName Mohammad-Mehdi
242 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015610621747.52
243 rdf:type schema:Person
244 sg:person.0627706332.00 schema:affiliation https://www.grid.ac/institutes/grid.412266.5
245 schema:familyName Ravanbod
246 schema:givenName Roya
247 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0627706332.00
248 rdf:type schema:Person
249 sg:person.0641532123.05 schema:affiliation https://www.grid.ac/institutes/grid.417689.5
250 schema:familyName Kazemnejad
251 schema:givenName Somaieh
252 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0641532123.05
253 rdf:type schema:Person
254 sg:person.0700447670.58 schema:affiliation https://www.grid.ac/institutes/grid.417689.5
255 schema:familyName Heidari-Vala
256 schema:givenName Hamed
257 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0700447670.58
258 rdf:type schema:Person
259 sg:person.0711321331.20 schema:affiliation https://www.grid.ac/institutes/grid.412266.5
260 schema:familyName Torkaman
261 schema:givenName Giti
262 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0711321331.20
263 rdf:type schema:Person
264 sg:person.0751705432.41 schema:affiliation https://www.grid.ac/institutes/grid.411705.6
265 schema:familyName Tahmasebi
266 schema:givenName Mohammad-Naghi
267 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0751705432.41
268 rdf:type schema:Person
269 sg:pub.10.1007/10_013 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004128903
270 https://doi.org/10.1007/10_013
271 rdf:type schema:CreativeWork
272 sg:pub.10.1007/7651_2013_9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014139500
273 https://doi.org/10.1007/7651_2013_9
274 rdf:type schema:CreativeWork
275 sg:pub.10.1007/s00167-008-0663-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049889875
276 https://doi.org/10.1007/s00167-008-0663-2
277 rdf:type schema:CreativeWork
278 sg:pub.10.1007/s00167-012-1891-z schema:sameAs https://app.dimensions.ai/details/publication/pub.1024994157
279 https://doi.org/10.1007/s00167-012-1891-z
280 rdf:type schema:CreativeWork
281 sg:pub.10.1007/s10856-013-4944-z schema:sameAs https://app.dimensions.ai/details/publication/pub.1048733090
282 https://doi.org/10.1007/s10856-013-4944-z
283 rdf:type schema:CreativeWork
284 sg:pub.10.1038/nbt0794-689 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026197737
285 https://doi.org/10.1038/nbt0794-689
286 rdf:type schema:CreativeWork
287 sg:pub.10.1038/nmat1822 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034972931
288 https://doi.org/10.1038/nmat1822
289 rdf:type schema:CreativeWork
290 https://doi.org/10.1002/jbm.a.34537 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029473293
291 rdf:type schema:CreativeWork
292 https://doi.org/10.1002/jbm.b.31571 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021684323
293 rdf:type schema:CreativeWork
294 https://doi.org/10.1016/j.actbio.2014.10.021 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010350354
295 rdf:type schema:CreativeWork
296 https://doi.org/10.1016/j.addr.2012.09.043 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045806998
297 rdf:type schema:CreativeWork
298 https://doi.org/10.1016/j.biomaterials.2004.01.066 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024139372
299 rdf:type schema:CreativeWork
300 https://doi.org/10.1016/j.biomaterials.2004.09.020 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045808018
301 rdf:type schema:CreativeWork
302 https://doi.org/10.1016/j.biomaterials.2006.07.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042455575
303 rdf:type schema:CreativeWork
304 https://doi.org/10.1016/j.biomaterials.2008.05.002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018314625
305 rdf:type schema:CreativeWork
306 https://doi.org/10.1016/j.biomaterials.2009.01.016 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030394320
307 rdf:type schema:CreativeWork
308 https://doi.org/10.1016/j.biomaterials.2012.06.058 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015543267
309 rdf:type schema:CreativeWork
310 https://doi.org/10.1016/j.biomaterials.2012.09.017 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023007257
311 rdf:type schema:CreativeWork
312 https://doi.org/10.1016/j.biomaterials.2013.04.055 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017702671
313 rdf:type schema:CreativeWork
314 https://doi.org/10.1016/j.biotechadv.2012.11.004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015536301
315 rdf:type schema:CreativeWork
316 https://doi.org/10.1016/j.jbiomech.2006.03.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019531333
317 rdf:type schema:CreativeWork
318 https://doi.org/10.1016/j.jbiosc.2014.05.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040388276
319 rdf:type schema:CreativeWork
320 https://doi.org/10.1016/j.progpolymsci.2007.05.013 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039308756
321 rdf:type schema:CreativeWork
322 https://doi.org/10.1016/s0142-9612(00)00121-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048945344
323 rdf:type schema:CreativeWork
324 https://doi.org/10.1016/s0142-9612(02)00353-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048889849
325 rdf:type schema:CreativeWork
326 https://doi.org/10.1016/s0142-9612(96)00117-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040067754
327 rdf:type schema:CreativeWork
328 https://doi.org/10.1016/s0142-9612(97)00190-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017618751
329 rdf:type schema:CreativeWork
330 https://doi.org/10.1053/joca.1997.0092 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001429888
331 rdf:type schema:CreativeWork
332 https://doi.org/10.1053/joca.2001.0438 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020080860
333 rdf:type schema:CreativeWork
334 https://doi.org/10.1089/cell.2012.0002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1078597127
335 rdf:type schema:CreativeWork
336 https://doi.org/10.1089/ten.1998.4.429 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059313133
337 rdf:type schema:CreativeWork
338 https://doi.org/10.1089/ten.2006.0181 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059313561
339 rdf:type schema:CreativeWork
340 https://doi.org/10.1097/00006534-199906000-00001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018333273
341 rdf:type schema:CreativeWork
342 https://doi.org/10.1097/sap.0b013e3181d6e38b schema:sameAs https://app.dimensions.ai/details/publication/pub.1051601989
343 rdf:type schema:CreativeWork
344 https://doi.org/10.1111/j.1525-1594.2005.00137.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1005255291
345 rdf:type schema:CreativeWork
346 https://doi.org/10.1126/science.1188936 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002257404
347 rdf:type schema:CreativeWork
348 https://doi.org/10.1177/0363546503259616 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043483314
349 rdf:type schema:CreativeWork
350 https://doi.org/10.1177/1947603510366027 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009012733
351 rdf:type schema:CreativeWork
352 https://doi.org/10.1371/journal.pone.0080004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046664664
353 rdf:type schema:CreativeWork
354 https://doi.org/10.2106/jbjs.k.00748 schema:sameAs https://app.dimensions.ai/details/publication/pub.1068902588
355 rdf:type schema:CreativeWork
356 https://doi.org/10.3791/4423 schema:sameAs https://app.dimensions.ai/details/publication/pub.1071423498
357 rdf:type schema:CreativeWork
358 https://doi.org/10.4161/org.6116 schema:sameAs https://app.dimensions.ai/details/publication/pub.1072306931
359 rdf:type schema:CreativeWork
360 https://www.grid.ac/institutes/grid.411705.6 schema:alternateName Tehran University of Medical Sciences
361 schema:name Orthopedic Department, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran
362 rdf:type schema:Organization
363 https://www.grid.ac/institutes/grid.411746.1 schema:alternateName Iran University of Medical Sciences
364 schema:name Razi Drug Research Center, Iran University of Medical Sciences, Tehran, Iran
365 rdf:type schema:Organization
366 https://www.grid.ac/institutes/grid.412266.5 schema:alternateName Tarbiat Modares University
367 schema:name Department of Physical Therapy, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran
368 rdf:type schema:Organization
369 https://www.grid.ac/institutes/grid.417689.5 schema:alternateName Academic Center for Education, Culture and Research
370 schema:name Reproductive Biotechnology Research Center, Avicenna Research Institute, Academic Center for Education, Culture and Research (ACECR), P.O. Box: 19615-1177, Tehran, Iran
371 rdf:type schema:Organization
372 https://www.grid.ac/institutes/grid.46072.37 schema:alternateName University of Tehran
373 schema:name Department of Pathology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran
374 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...