Refined localization of a gene for pediatric gastroesophageal reflux makes HTR2A an unlikely candidate gene View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2000-11

AUTHORS

Fen Hu, J. Post, Sandra Johnson, Garth Ehrlich, Robert Preston

ABSTRACT

. Our objective in this study was to determine whether mutations in the gene for the 5-hydroxytryptamine receptor 2A (HTR2A) cause the autosomal dominant form of severe pediatric gastroesophageal reflux (GER), which we had previously mapped to a 21-cM region at chromosome 13q14. Direct sequencing of the HTR2A gene was carried out on DNA from affected and unaffected members of families with severe pediatric GER displaying genetic linkage to the HTR2A locus. In addition, we performed high-resolution linkage mapping within the GER gene region using additional polymorphic markers closely linked to HTR2A. Several previously reported polymorphisms in the HTR2A gene were identified in three families affected with GER. In addition, we identified a novel polymorphism at nucleotide –1273 in the HTR2A promoter. No mutant allele cosegregated exclusively with the GER phenotype in any family. Linkage analysis using additional polymorphic markers narrowed the region of the GER gene to a 9 cM interval between markers D13S263 and CAGR1, formally excluding HTR2A as a candidate gene. In conclusion, sequence analysis of HTR2A and linkage analysis argue against mutations in HTR2A being a cause of severe pediatric GER. More... »

PAGES

519-525

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s004390000405

DOI

http://dx.doi.org/10.1007/s004390000405

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1026061586

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/11140952


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0604", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Genetics", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Child", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Chromosome Mapping", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Chromosomes, Human, Pair 13", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Exons", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Family", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Gastroesophageal Reflux", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Genetic Linkage", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Genetic Markers", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Haplotypes", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Pedigree", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Polymerase Chain Reaction", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Polymorphism, Genetic", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Receptor, Serotonin, 5-HT2A", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Receptors, Serotonin", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Reference Values", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Center for Genomic Sciences, Allegheny-Singer Research Institute, Allegheny General Hospital, 320 East North Ave., 10th Floor South Tower, Pittsburgh, PA 15212, USA", 
          "id": "http://www.grid.ac/institutes/grid.413621.3", 
          "name": [
            "Center for Genomic Sciences, Allegheny-Singer Research Institute, Allegheny General Hospital, 320 East North Ave., 10th Floor South Tower, Pittsburgh, PA 15212, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hu", 
        "givenName": "Fen", 
        "id": "sg:person.010625263442.13", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010625263442.13"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Center for Genomic Sciences, Allegheny-Singer Research Institute, Allegheny General Hospital, 320 East North Ave., 10th Floor South Tower, Pittsburgh, PA 15212, USA", 
          "id": "http://www.grid.ac/institutes/grid.413621.3", 
          "name": [
            "Center for Genomic Sciences, Allegheny-Singer Research Institute, Allegheny General Hospital, 320 East North Ave., 10th Floor South Tower, Pittsburgh, PA 15212, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Post", 
        "givenName": "J.", 
        "id": "sg:person.01055120221.02", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01055120221.02"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Center for Genomic Sciences, Allegheny-Singer Research Institute, Allegheny General Hospital, 320 East North Ave., 10th Floor South Tower, Pittsburgh, PA 15212, USA", 
          "id": "http://www.grid.ac/institutes/grid.413621.3", 
          "name": [
            "Center for Genomic Sciences, Allegheny-Singer Research Institute, Allegheny General Hospital, 320 East North Ave., 10th Floor South Tower, Pittsburgh, PA 15212, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Johnson", 
        "givenName": "Sandra", 
        "id": "sg:person.013716663707.66", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013716663707.66"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Center for Genomic Sciences, Allegheny-Singer Research Institute, Allegheny General Hospital, 320 East North Ave., 10th Floor South Tower, Pittsburgh, PA 15212, USA", 
          "id": "http://www.grid.ac/institutes/grid.413621.3", 
          "name": [
            "Center for Genomic Sciences, Allegheny-Singer Research Institute, Allegheny General Hospital, 320 East North Ave., 10th Floor South Tower, Pittsburgh, PA 15212, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ehrlich", 
        "givenName": "Garth", 
        "id": "sg:person.01324252605.57", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01324252605.57"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Center for Genomic Sciences, Allegheny-Singer Research Institute, Allegheny General Hospital, 320 East North Ave., 10th Floor South Tower, Pittsburgh, PA 15212, USA", 
          "id": "http://www.grid.ac/institutes/grid.413621.3", 
          "name": [
            "Center for Genomic Sciences, Allegheny-Singer Research Institute, Allegheny General Hospital, 320 East North Ave., 10th Floor South Tower, Pittsburgh, PA 15212, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Preston", 
        "givenName": "Robert", 
        "id": "sg:person.016613647662.83", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016613647662.83"
        ], 
        "type": "Person"
      }
    ], 
    "datePublished": "2000-11", 
    "datePublishedReg": "2000-11-01", 
    "description": "Abstract. Our objective in this study was to determine whether mutations in the gene for the 5-hydroxytryptamine receptor 2A (HTR2A) cause the autosomal dominant form of severe pediatric gastroesophageal reflux (GER), which we had previously mapped to a 21-cM region at chromosome 13q14. Direct sequencing of the HTR2A gene was carried out on DNA from affected and unaffected members of families with severe pediatric GER displaying genetic linkage to the HTR2A locus. In addition, we performed high-resolution linkage mapping within the GER gene region using additional polymorphic markers closely linked to HTR2A. Several previously reported polymorphisms in the HTR2A gene were identified in three families affected with GER. In addition, we identified a novel polymorphism at nucleotide \u20131273 in the HTR2A promoter. No mutant allele cosegregated exclusively with the GER phenotype in any family. Linkage analysis using additional polymorphic markers narrowed the region of the GER gene to a 9\u00a0cM interval between markers D13S263 and CAGR1, formally excluding HTR2A as a candidate gene. In conclusion, sequence analysis of HTR2A and linkage analysis argue against mutations in HTR2A being a cause of severe pediatric GER.", 
    "genre": "article", 
    "id": "sg:pub.10.1007/s004390000405", 
    "isAccessibleForFree": false, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.2627133", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2488116", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2488487", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2488072", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1085982", 
        "issn": [
          "0340-6717", 
          "1432-1203"
        ], 
        "name": "Human Genetics", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "5", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "107"
      }
    ], 
    "keywords": [
      "Pediatric Gastroesophageal Reflux", 
      "gastroesophageal reflux", 
      "HTR2A locus", 
      "autosomal dominant form", 
      "receptor 2A", 
      "direct sequencing", 
      "candidate genes", 
      "unaffected members", 
      "reflux", 
      "novel polymorphisms", 
      "chromosome 13q14", 
      "markers", 
      "polymorphism", 
      "genes", 
      "mutations", 
      "polymorphic markers", 
      "additional polymorphic markers", 
      "genetic linkage", 
      "D13S263", 
      "mutant alleles", 
      "unlikely candidate gene", 
      "cause", 
      "conclusion", 
      "phenotype", 
      "family", 
      "dominant form", 
      "alleles", 
      "sequence analysis", 
      "interval", 
      "gene region", 
      "addition", 
      "sequencing", 
      "study", 
      "analysis", 
      "localization", 
      "objective", 
      "promoter", 
      "cM interval", 
      "DNA", 
      "region", 
      "members", 
      "nucleotides", 
      "refined localization", 
      "loci", 
      "form", 
      "linkage", 
      "mapping", 
      "linkage mapping", 
      "high-resolution linkage mapping"
    ], 
    "name": "Refined localization of a gene for pediatric gastroesophageal reflux makes HTR2A an unlikely candidate gene", 
    "pagination": "519-525", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1026061586"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s004390000405"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "11140952"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s004390000405", 
      "https://app.dimensions.ai/details/publication/pub.1026061586"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-08-04T16:53", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20220804/entities/gbq_results/article/article_322.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1007/s004390000405"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s004390000405'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s004390000405'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s004390000405'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s004390000405'


 

This table displays all metadata directly associated to this object as RDF triples.

218 TRIPLES      20 PREDICATES      93 URIs      85 LITERALS      25 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s004390000405 schema:about N0b9731d6f76346aa9b95114ec0b2e03e
2 N155a48c41aac46a2a6edef058ea37b72
3 N20db43571d2143daba3f97d6c9a983e3
4 N3c46d376833a4b8580b448c4ff798083
5 N4535f94f23fe4f8a84011feda30046e2
6 N4b7c5fc0ed504508b3c7da50e6569e77
7 N5fb5860a648b43d79a33a8adff43f952
8 N711f9e2b737e4c30b86b2027be9a7111
9 N80d07a9dc44545938a1be6e01b81f333
10 N9569bfd47fc04df592dbc8572c42d1e3
11 N9e803fa3e7c243b9ab9f62ec1d3cdbc4
12 Na54b6783481e49e097531a4b6c4e3279
13 Nadf298ed42d643e8ba8d567f2cd3f771
14 Nc10f90b859114586989938f49cc6527e
15 Ne96bf95d153e47578f487ba15a3153c6
16 Nf0012b112fe248258ea4e30a07d7b167
17 Nf75eec21d0a342258d3b518fb8426032
18 Nfe1d84aa85414422afb268d29f3de56a
19 anzsrc-for:06
20 anzsrc-for:0604
21 schema:author N5ab17f8689804219b8a6323cecb25fa9
22 schema:datePublished 2000-11
23 schema:datePublishedReg 2000-11-01
24 schema:description Abstract. Our objective in this study was to determine whether mutations in the gene for the 5-hydroxytryptamine receptor 2A (HTR2A) cause the autosomal dominant form of severe pediatric gastroesophageal reflux (GER), which we had previously mapped to a 21-cM region at chromosome 13q14. Direct sequencing of the HTR2A gene was carried out on DNA from affected and unaffected members of families with severe pediatric GER displaying genetic linkage to the HTR2A locus. In addition, we performed high-resolution linkage mapping within the GER gene region using additional polymorphic markers closely linked to HTR2A. Several previously reported polymorphisms in the HTR2A gene were identified in three families affected with GER. In addition, we identified a novel polymorphism at nucleotide –1273 in the HTR2A promoter. No mutant allele cosegregated exclusively with the GER phenotype in any family. Linkage analysis using additional polymorphic markers narrowed the region of the GER gene to a 9 cM interval between markers D13S263 and CAGR1, formally excluding HTR2A as a candidate gene. In conclusion, sequence analysis of HTR2A and linkage analysis argue against mutations in HTR2A being a cause of severe pediatric GER.
25 schema:genre article
26 schema:isAccessibleForFree false
27 schema:isPartOf N5a553ab0011d43bba96cf4547f542a4d
28 Nf636e11d24f04e0abd06146c7498f8c6
29 sg:journal.1085982
30 schema:keywords D13S263
31 DNA
32 HTR2A locus
33 Pediatric Gastroesophageal Reflux
34 addition
35 additional polymorphic markers
36 alleles
37 analysis
38 autosomal dominant form
39 cM interval
40 candidate genes
41 cause
42 chromosome 13q14
43 conclusion
44 direct sequencing
45 dominant form
46 family
47 form
48 gastroesophageal reflux
49 gene region
50 genes
51 genetic linkage
52 high-resolution linkage mapping
53 interval
54 linkage
55 linkage mapping
56 localization
57 loci
58 mapping
59 markers
60 members
61 mutant alleles
62 mutations
63 novel polymorphisms
64 nucleotides
65 objective
66 phenotype
67 polymorphic markers
68 polymorphism
69 promoter
70 receptor 2A
71 refined localization
72 reflux
73 region
74 sequence analysis
75 sequencing
76 study
77 unaffected members
78 unlikely candidate gene
79 schema:name Refined localization of a gene for pediatric gastroesophageal reflux makes HTR2A an unlikely candidate gene
80 schema:pagination 519-525
81 schema:productId N2149fb16e45c4cea81462dcd00097ba7
82 N97e8600a03a3473f81aa5785752a1154
83 Nc6f036c6fade42538744ed52448aca75
84 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026061586
85 https://doi.org/10.1007/s004390000405
86 schema:sdDatePublished 2022-08-04T16:53
87 schema:sdLicense https://scigraph.springernature.com/explorer/license/
88 schema:sdPublisher N6e8e321b77914b79a2f4c48b79d176e3
89 schema:url https://doi.org/10.1007/s004390000405
90 sgo:license sg:explorer/license/
91 sgo:sdDataset articles
92 rdf:type schema:ScholarlyArticle
93 N0b9731d6f76346aa9b95114ec0b2e03e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
94 schema:name Polymorphism, Genetic
95 rdf:type schema:DefinedTerm
96 N155a48c41aac46a2a6edef058ea37b72 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
97 schema:name Exons
98 rdf:type schema:DefinedTerm
99 N20db43571d2143daba3f97d6c9a983e3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
100 schema:name Family
101 rdf:type schema:DefinedTerm
102 N2149fb16e45c4cea81462dcd00097ba7 schema:name doi
103 schema:value 10.1007/s004390000405
104 rdf:type schema:PropertyValue
105 N30e2ff0201744a02815f7e0c723d17e8 rdf:first sg:person.01324252605.57
106 rdf:rest N7146377bce2f495c923f812e3da60a4b
107 N3c46d376833a4b8580b448c4ff798083 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
108 schema:name Pedigree
109 rdf:type schema:DefinedTerm
110 N4535f94f23fe4f8a84011feda30046e2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
111 schema:name Child
112 rdf:type schema:DefinedTerm
113 N4b7c5fc0ed504508b3c7da50e6569e77 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
114 schema:name Gastroesophageal Reflux
115 rdf:type schema:DefinedTerm
116 N53f12f2850d84f8d9cd17a8d55c0e03e rdf:first sg:person.013716663707.66
117 rdf:rest N30e2ff0201744a02815f7e0c723d17e8
118 N5a553ab0011d43bba96cf4547f542a4d schema:volumeNumber 107
119 rdf:type schema:PublicationVolume
120 N5ab17f8689804219b8a6323cecb25fa9 rdf:first sg:person.010625263442.13
121 rdf:rest Ne099b9e5e2474da0ac6ff35707046fcd
122 N5fb5860a648b43d79a33a8adff43f952 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
123 schema:name Polymerase Chain Reaction
124 rdf:type schema:DefinedTerm
125 N6e8e321b77914b79a2f4c48b79d176e3 schema:name Springer Nature - SN SciGraph project
126 rdf:type schema:Organization
127 N711f9e2b737e4c30b86b2027be9a7111 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
128 schema:name Genetic Markers
129 rdf:type schema:DefinedTerm
130 N7146377bce2f495c923f812e3da60a4b rdf:first sg:person.016613647662.83
131 rdf:rest rdf:nil
132 N80d07a9dc44545938a1be6e01b81f333 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
133 schema:name Reference Values
134 rdf:type schema:DefinedTerm
135 N9569bfd47fc04df592dbc8572c42d1e3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
136 schema:name Haplotypes
137 rdf:type schema:DefinedTerm
138 N97e8600a03a3473f81aa5785752a1154 schema:name dimensions_id
139 schema:value pub.1026061586
140 rdf:type schema:PropertyValue
141 N9e803fa3e7c243b9ab9f62ec1d3cdbc4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
142 schema:name Genetic Linkage
143 rdf:type schema:DefinedTerm
144 Na54b6783481e49e097531a4b6c4e3279 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
145 schema:name Chromosome Mapping
146 rdf:type schema:DefinedTerm
147 Nadf298ed42d643e8ba8d567f2cd3f771 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
148 schema:name Receptors, Serotonin
149 rdf:type schema:DefinedTerm
150 Nc10f90b859114586989938f49cc6527e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
151 schema:name Female
152 rdf:type schema:DefinedTerm
153 Nc6f036c6fade42538744ed52448aca75 schema:name pubmed_id
154 schema:value 11140952
155 rdf:type schema:PropertyValue
156 Ne099b9e5e2474da0ac6ff35707046fcd rdf:first sg:person.01055120221.02
157 rdf:rest N53f12f2850d84f8d9cd17a8d55c0e03e
158 Ne96bf95d153e47578f487ba15a3153c6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
159 schema:name Male
160 rdf:type schema:DefinedTerm
161 Nf0012b112fe248258ea4e30a07d7b167 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
162 schema:name Humans
163 rdf:type schema:DefinedTerm
164 Nf636e11d24f04e0abd06146c7498f8c6 schema:issueNumber 5
165 rdf:type schema:PublicationIssue
166 Nf75eec21d0a342258d3b518fb8426032 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
167 schema:name Chromosomes, Human, Pair 13
168 rdf:type schema:DefinedTerm
169 Nfe1d84aa85414422afb268d29f3de56a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
170 schema:name Receptor, Serotonin, 5-HT2A
171 rdf:type schema:DefinedTerm
172 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
173 schema:name Biological Sciences
174 rdf:type schema:DefinedTerm
175 anzsrc-for:0604 schema:inDefinedTermSet anzsrc-for:
176 schema:name Genetics
177 rdf:type schema:DefinedTerm
178 sg:grant.2488072 http://pending.schema.org/fundedItem sg:pub.10.1007/s004390000405
179 rdf:type schema:MonetaryGrant
180 sg:grant.2488116 http://pending.schema.org/fundedItem sg:pub.10.1007/s004390000405
181 rdf:type schema:MonetaryGrant
182 sg:grant.2488487 http://pending.schema.org/fundedItem sg:pub.10.1007/s004390000405
183 rdf:type schema:MonetaryGrant
184 sg:grant.2627133 http://pending.schema.org/fundedItem sg:pub.10.1007/s004390000405
185 rdf:type schema:MonetaryGrant
186 sg:journal.1085982 schema:issn 0340-6717
187 1432-1203
188 schema:name Human Genetics
189 schema:publisher Springer Nature
190 rdf:type schema:Periodical
191 sg:person.01055120221.02 schema:affiliation grid-institutes:grid.413621.3
192 schema:familyName Post
193 schema:givenName J.
194 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01055120221.02
195 rdf:type schema:Person
196 sg:person.010625263442.13 schema:affiliation grid-institutes:grid.413621.3
197 schema:familyName Hu
198 schema:givenName Fen
199 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010625263442.13
200 rdf:type schema:Person
201 sg:person.01324252605.57 schema:affiliation grid-institutes:grid.413621.3
202 schema:familyName Ehrlich
203 schema:givenName Garth
204 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01324252605.57
205 rdf:type schema:Person
206 sg:person.013716663707.66 schema:affiliation grid-institutes:grid.413621.3
207 schema:familyName Johnson
208 schema:givenName Sandra
209 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013716663707.66
210 rdf:type schema:Person
211 sg:person.016613647662.83 schema:affiliation grid-institutes:grid.413621.3
212 schema:familyName Preston
213 schema:givenName Robert
214 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016613647662.83
215 rdf:type schema:Person
216 grid-institutes:grid.413621.3 schema:alternateName Center for Genomic Sciences, Allegheny-Singer Research Institute, Allegheny General Hospital, 320 East North Ave., 10th Floor South Tower, Pittsburgh, PA 15212, USA
217 schema:name Center for Genomic Sciences, Allegheny-Singer Research Institute, Allegheny General Hospital, 320 East North Ave., 10th Floor South Tower, Pittsburgh, PA 15212, USA
218 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...