Alu insertion polymorphisms in NW Africa and the Iberian Peninsula: evidence for a strong genetic boundary through the Gibraltar Straits View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2000-10

AUTHORS

David Comas, Francesc Calafell, Noufissa Benchemsi, Ahmed Helal, Gerard Lefranc, Mark Stoneking, Mark A. Batzer, Jaume Bertranpetit, Antti Sajantila

ABSTRACT

An analysis of 11 I Alu insertion polymorphisms (ACE, TPA25, PV92, APO, FXIIIB, D1, A25, B65, HS2.43, HS3.23, and HS4.65) has been performed in several NW African (Northern, Western, and Southeastern Moroccans, Saharawi; Algerians; Tunisians) and Iberian (Basques, Catalans, and Andalusians) populations. Genetic distances and principal component analyses show a clear differentiation of NW African and Iberian groups of samples, suggesting a strong genetic barrier matching the geographical Mediterranean Sea barrier. The restriction to gene flow may be attributed to the navigational hazards across the Straits, but cultural factors must also have played a role. Some degree of gene flow from sub-Saharan Africa can be detected in the southern part of North Africa and in Saharawi and Southeastern Moroccans, as a result of a continuous gene flow across the Sahara desert that has created a south-north cline of sub-Saharan Africa influence in North Africa. Iberian samples show a substantial degree of homogeneity and fall within the cluster of European-based genetic diversity. More... »

PAGES

312-319

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s004390000370

DOI

http://dx.doi.org/10.1007/s004390000370

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1027002286

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/11129330


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