Genome-wide association of familial prostate cancer cases identifies evidence for a rare segregating haplotype at 8q24.21 View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2016-08

AUTHORS

Craig C. Teerlink, Daniel Leongamornlert, Tokhir Dadaev, Alun Thomas, James Farnham, Robert A. Stephenson, Shaun Riska, Shannon K. McDonnell, Daniel J. Schaid, William J. Catalona, S. Lilly Zheng, Kathleen A. Cooney, Anna M. Ray, Kimberly A. Zuhlke, Ethan M. Lange, Graham G. Giles, Melissa C. Southey, Liesel M. Fitzgerald, Antje Rinckleb, Manuel Luedeke, Christiane Maier, Janet L. Stanford, Elaine A. Ostrander, Elina M. Kaikkonen, Csilla Sipeky, Teuvo Tammela, Johanna Schleutker, Kathleen E. Wiley, Sarah D. Isaacs, Patrick C. Walsh, William B. Isaacs, Jianfeng Xu, Geraldine Cancel-Tassin, Olivier Cussenot, Diptasri Mandal, Cecelia Laurie, Cathy Laurie, The PRACTICAL consortium, International Consortium for Prostate Cancer Genetics, Stephen N. Thibodeau, Rosalind A. Eeles, Zsofia Kote-Jarai, Lisa Cannon-Albright

ABSTRACT

Previous genome-wide association studies (GWAS) of prostate cancer risk focused on cases unselected for family history and have reported over 100 significant associations. The International Consortium for Prostate Cancer Genetics (ICPCG) has now performed a GWAS of 2511 (unrelated) familial prostate cancer cases and 1382 unaffected controls from 12 member sites. All samples were genotyped on the Illumina 5M+exome single nucleotide polymorphism (SNP) platform. The GWAS identified a significant evidence for association for SNPs in six regions previously associated with prostate cancer in population-based cohorts, including 3q26.2, 6q25.3, 8q24.21, 10q11.23, 11q13.3, and 17q12. Of note, SNP rs138042437 (p = 1.7e(-8)) at 8q24.21 achieved a large estimated effect size in this cohort (odds ratio = 13.3). 116 previously sampled affected relatives of 62 risk-allele carriers from the GWAS cohort were genotyped for this SNP, identifying 78 additional affected carriers in 62 pedigrees. A test for an excess number of affected carriers among relatives exhibited strong evidence for co-segregation of the variant with disease (p = 8.5e(-11)). The majority (92 %) of risk-allele carriers at rs138042437 had a consistent estimated haplotype spanning approximately 100 kb of 8q24.21 that contained the minor alleles of three rare SNPs (dosage minor allele frequencies <1.7 %), rs183373024 (PRNCR1), previously associated SNP rs188140481, and rs138042437 (CASC19). Strong evidence for co-segregation of a SNP on the haplotype further characterizes the haplotype as a prostate cancer predisposition locus. More... »

PAGES

923-938

References to SciGraph publications

  • 2007-05. Genome-wide association study of prostate cancer identifies a second risk locus at 8q24 in NATURE GENETICS
  • 2013-04. Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array in NATURE GENETICS
  • 2014-02. G84E mutation in HOXB13 is firmly associated with prostate cancer risk: a meta-analysis in TUMOR BIOLOGY
  • 2011-08. Seven prostate cancer susceptibility loci identified by a multi-stage genome-wide association study in NATURE GENETICS
  • 2007-08. Two variants on chromosome 17 confer prostate cancer risk, and the one in TCF2 protects against type 2 diabetes in NATURE GENETICS
  • 2010-07. New approaches to population stratification in genome-wide association studies in NATURE REVIEWS GENETICS
  • 2007-05. Genome-wide association study identifies a second prostate cancer susceptibility variant at 8q24 in NATURE GENETICS
  • 2009-10. Multiple loci on 8q24 associated with prostate cancer susceptibility in NATURE GENETICS
  • 2008-03. Multiple loci identified in a genome-wide association study of prostate cancer in NATURE GENETICS
  • 2008-03. Multiple newly identified loci associated with prostate cancer susceptibility in NATURE GENETICS
  • 2012-02. A linear complexity phasing method for thousands of genomes in NATURE METHODS
  • 2015-12. Two susceptibility loci identified for prostate cancer aggressiveness in NATURE COMMUNICATIONS
  • 2014-10. A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer in NATURE GENETICS
  • 2012-12. A study based on whole-genome sequencing yields a rare variant at 8q24 associated with prostate cancer in NATURE GENETICS
  • 2007-05. Multiple regions within 8q24 independently affect risk for prostate cancer in NATURE GENETICS
  • 2006-06. A common variant associated with prostate cancer in European and African populations in NATURE GENETICS
  • 2011-06. Genome-wide association study of prostate cancer in men of African ancestry identifies a susceptibility locus at 17q21 in NATURE GENETICS
  • 2006-11. Pooled genome linkage scan of aggressive prostate cancer: results from the International Consortium for Prostate Cancer Genetics in HUMAN GENETICS
  • 2009-10. Genome-wide association and replication studies identify four variants associated with prostate cancer susceptibility in NATURE GENETICS
  • 2015-04. Associations of prostate cancer risk variants with disease aggressiveness: results of the NCI-SPORE Genetics Working Group analysis of 18,343 cases in HUMAN GENETICS
  • 2008-10. Evidence for two independent prostate cancer risk–associated loci in the HNF1B gene at 17q12 in NATURE GENETICS
  • 2008-03. Common sequence variants on 2p15 and Xp11.22 confer susceptibility to prostate cancer in NATURE GENETICS
  • 2012-11. An integrated map of genetic variation from 1,092 human genomes in NATURE
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s00439-016-1690-6

    DOI

    http://dx.doi.org/10.1007/s00439-016-1690-6

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1011561241

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/27262462


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1112", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Oncology and Carcinogenesis", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Medical and Health Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Aged", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Gene Frequency", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Genetic Predisposition to Disease", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Genome-Wide Association Study", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Genotype", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Haplotypes", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Heterozygote", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Humans", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Male", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Middle Aged", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Pedigree", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Polymorphism, Single Nucleotide", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Prostatic Neoplasms", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "RNA, Long Noncoding", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Risk Factors", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Tumor Suppressor Proteins", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "affiliation": {
              "alternateName": "University of Utah", 
              "id": "https://www.grid.ac/institutes/grid.223827.e", 
              "name": [
                "Department of Internal Medicine, University of Utah School of Medicine, 84108, Salt Lake City, UT, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Teerlink", 
            "givenName": "Craig C.", 
            "id": "sg:person.01016504312.27", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01016504312.27"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Institute of Cancer Research", 
              "id": "https://www.grid.ac/institutes/grid.18886.3f", 
              "name": [
                "Division of Genetics and Epidemiology, Institute of Cancer Research, SW7 3RP, London, UK"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Leongamornlert", 
            "givenName": "Daniel", 
            "id": "sg:person.01070241414.27", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01070241414.27"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Institute of Cancer Research", 
              "id": "https://www.grid.ac/institutes/grid.18886.3f", 
              "name": [
                "Division of Genetics and Epidemiology, Institute of Cancer Research, SW7 3RP, London, UK"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Dadaev", 
            "givenName": "Tokhir", 
            "id": "sg:person.01003416206.40", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01003416206.40"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Utah", 
              "id": "https://www.grid.ac/institutes/grid.223827.e", 
              "name": [
                "Department of Internal Medicine, University of Utah School of Medicine, 84108, Salt Lake City, UT, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Thomas", 
            "givenName": "Alun", 
            "id": "sg:person.01237602223.31", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01237602223.31"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Utah", 
              "id": "https://www.grid.ac/institutes/grid.223827.e", 
              "name": [
                "Department of Internal Medicine, University of Utah School of Medicine, 84108, Salt Lake City, UT, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Farnham", 
            "givenName": "James", 
            "id": "sg:person.012350263567.50", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012350263567.50"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Utah Health Care", 
              "id": "https://www.grid.ac/institutes/grid.412722.0", 
              "name": [
                "Department of Urology, University of Utah School of Medicine, 84132, Salt Lake City, UT, USA", 
                "Department of Surgery, University of Utah School of Medicine, 84132, Salt Lake City, UT, USA", 
                "Huntsman Cancer Institute, University of Utah, 84112, Salt Lake City, UT, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Stephenson", 
            "givenName": "Robert A.", 
            "id": "sg:person.01257674522.66", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01257674522.66"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Mayo Clinic", 
              "id": "https://www.grid.ac/institutes/grid.66875.3a", 
              "name": [
                "Department of Health Sciences Research, Mayo Clinic, 55905, Rochester, MN, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Riska", 
            "givenName": "Shaun", 
            "id": "sg:person.0750731602.70", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0750731602.70"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Mayo Clinic", 
              "id": "https://www.grid.ac/institutes/grid.66875.3a", 
              "name": [
                "Department of Health Sciences Research, Mayo Clinic, 55905, Rochester, MN, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "McDonnell", 
            "givenName": "Shannon K.", 
            "id": "sg:person.01177163404.55", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01177163404.55"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Mayo Clinic", 
              "id": "https://www.grid.ac/institutes/grid.66875.3a", 
              "name": [
                "Department of Health Sciences Research, Mayo Clinic, 55905, Rochester, MN, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Schaid", 
            "givenName": "Daniel J.", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Northwestern University", 
              "id": "https://www.grid.ac/institutes/grid.16753.36", 
              "name": [
                "Feinberg School of Medicine, Northwestern University, 60611, Chicago, IL, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Catalona", 
            "givenName": "William J.", 
            "id": "sg:person.01170256773.00", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01170256773.00"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Northwestern University", 
              "id": "https://www.grid.ac/institutes/grid.16753.36", 
              "name": [
                "Feinberg School of Medicine, Northwestern University, 60611, Chicago, IL, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Zheng", 
            "givenName": "S. Lilly", 
            "id": "sg:person.014056437627.94", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014056437627.94"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Michigan\u2013Ann Arbor", 
              "id": "https://www.grid.ac/institutes/grid.214458.e", 
              "name": [
                "Department of Internal Medicine, University of Michigan Medical School, 48109, Ann Arbor, MI, USA", 
                "Department of Urology, University of Michigan Medical School, 48109, Ann Arbor, MI, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Cooney", 
            "givenName": "Kathleen A.", 
            "id": "sg:person.01355260210.43", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01355260210.43"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Michigan\u2013Ann Arbor", 
              "id": "https://www.grid.ac/institutes/grid.214458.e", 
              "name": [
                "Department of Internal Medicine, University of Michigan Medical School, 48109, Ann Arbor, MI, USA", 
                "Department of Urology, University of Michigan Medical School, 48109, Ann Arbor, MI, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Ray", 
            "givenName": "Anna M.", 
            "id": "sg:person.01113677032.85", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01113677032.85"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Michigan\u2013Ann Arbor", 
              "id": "https://www.grid.ac/institutes/grid.214458.e", 
              "name": [
                "Department of Internal Medicine, University of Michigan Medical School, 48109, Ann Arbor, MI, USA", 
                "Department of Urology, University of Michigan Medical School, 48109, Ann Arbor, MI, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Zuhlke", 
            "givenName": "Kimberly A.", 
            "id": "sg:person.01241031610.88", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01241031610.88"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of North Carolina System", 
              "id": "https://www.grid.ac/institutes/grid.410711.2", 
              "name": [
                "Department of Genetics, University of North Carolina, 27599, Chapel Hill, NC, USA", 
                "Department of Biostatistics, University of North Carolina, 27599, Chapel Hill, NC, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Lange", 
            "givenName": "Ethan M.", 
            "id": "sg:person.01340276667.21", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01340276667.21"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Monash University", 
              "id": "https://www.grid.ac/institutes/grid.1002.3", 
              "name": [
                "Cancer Epidemiology Centre, Cancer Council Victoria, 3004, Melbourne, Australia", 
                "Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, 3010, Melbourne, VIC, Australia", 
                "Department of Epidemiology and Preventive Medicine, Monash University, 3004, Melbourne, VIC, Australia"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Giles", 
            "givenName": "Graham G.", 
            "id": "sg:person.0732505060.44", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0732505060.44"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Melbourne", 
              "id": "https://www.grid.ac/institutes/grid.1008.9", 
              "name": [
                "Department of Pathology, University of Melbourne, 3010, Melbourne, Australia"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Southey", 
            "givenName": "Melissa C.", 
            "id": "sg:person.014514614637.17", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014514614637.17"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Cancer Council Victoria", 
              "id": "https://www.grid.ac/institutes/grid.3263.4", 
              "name": [
                "Cancer Epidemiology Centre, Cancer Council Victoria, 3004, Melbourne, Australia"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Fitzgerald", 
            "givenName": "Liesel M.", 
            "id": "sg:person.01116216607.59", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01116216607.59"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University Hospital Ulm", 
              "id": "https://www.grid.ac/institutes/grid.410712.1", 
              "name": [
                "Department of Urology, University Hospital Ulm, 53179, Ulm, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Rinckleb", 
            "givenName": "Antje", 
            "id": "sg:person.0721307601.00", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0721307601.00"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University Hospital Ulm", 
              "id": "https://www.grid.ac/institutes/grid.410712.1", 
              "name": [
                "Department of Urology, University Hospital Ulm, 53179, Ulm, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Luedeke", 
            "givenName": "Manuel", 
            "id": "sg:person.01215575561.02", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01215575561.02"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Ulm", 
              "id": "https://www.grid.ac/institutes/grid.6582.9", 
              "name": [
                "Institute for Human Genetics, University of Ulm, 89081, Ulm, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Maier", 
            "givenName": "Christiane", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Fred Hutchinson Cancer Research Center", 
              "id": "https://www.grid.ac/institutes/grid.270240.3", 
              "name": [
                "Division of Public Health Sciences, Fred Hutchinson Cancer Research Center (FHCRC), 98109, Seattle, WA, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Stanford", 
            "givenName": "Janet L.", 
            "id": "sg:person.0623267507.88", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0623267507.88"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "National Human Genome Research Institute", 
              "id": "https://www.grid.ac/institutes/grid.280128.1", 
              "name": [
                "Cancer Genetics Branch, National Human Genome Research Institute (NHGRI), National Institutes of Health (NIH), 20892, Bethesda, MD, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Ostrander", 
            "givenName": "Elaine A.", 
            "id": "sg:person.013347276237.81", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013347276237.81"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Turku", 
              "id": "https://www.grid.ac/institutes/grid.1374.1", 
              "name": [
                "Department of Medical Biochemistry and Genetics, University of Turku, 20520, Turku, Finland"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Kaikkonen", 
            "givenName": "Elina M.", 
            "id": "sg:person.015660611161.08", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015660611161.08"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Turku", 
              "id": "https://www.grid.ac/institutes/grid.1374.1", 
              "name": [
                "Department of Medical Biochemistry and Genetics, University of Turku, 20520, Turku, Finland"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Sipeky", 
            "givenName": "Csilla", 
            "id": "sg:person.01123520621.15", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01123520621.15"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Tampere University Hospital", 
              "id": "https://www.grid.ac/institutes/grid.412330.7", 
              "name": [
                "Department of Urology, University of Tampere and Tampere University Hospital, 33520, Tampere, Finland"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Tammela", 
            "givenName": "Teuvo", 
            "id": "sg:person.0701403642.35", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0701403642.35"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Turku University Hospital", 
              "id": "https://www.grid.ac/institutes/grid.410552.7", 
              "name": [
                "Tyks Microbiology and Genetics, Department of Medical Genetics, Turku University Hospital, 20520, Turku, Finland"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Schleutker", 
            "givenName": "Johanna", 
            "id": "sg:person.0735116427.86", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0735116427.86"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Johns Hopkins University", 
              "id": "https://www.grid.ac/institutes/grid.21107.35", 
              "name": [
                "Brady Urological Institute, Johns Hopkins University, 21287, Baltimore, MD, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Wiley", 
            "givenName": "Kathleen E.", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Johns Hopkins University", 
              "id": "https://www.grid.ac/institutes/grid.21107.35", 
              "name": [
                "Brady Urological Institute, Johns Hopkins University, 21287, Baltimore, MD, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Isaacs", 
            "givenName": "Sarah D.", 
            "id": "sg:person.010145071237.85", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010145071237.85"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Johns Hopkins University", 
              "id": "https://www.grid.ac/institutes/grid.21107.35", 
              "name": [
                "Brady Urological Institute, Johns Hopkins University, 21287, Baltimore, MD, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Walsh", 
            "givenName": "Patrick C.", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Johns Hopkins University", 
              "id": "https://www.grid.ac/institutes/grid.21107.35", 
              "name": [
                "Brady Urological Institute, Johns Hopkins University, 21287, Baltimore, MD, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Isaacs", 
            "givenName": "William B.", 
            "id": "sg:person.01145536753.98", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01145536753.98"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "NorthShore University HealthSystem", 
              "id": "https://www.grid.ac/institutes/grid.240372.0", 
              "name": [
                "Program for Personalized Cancer Care, NorthShore University Health System, 60201, Evanston, IL, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Xu", 
            "givenName": "Jianfeng", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "name": [
                "CeRePP, Hopital Tenon, Assistance Publique-Hopitaux de Paris, 75020, Paris, France"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Cancel-Tassin", 
            "givenName": "Geraldine", 
            "id": "sg:person.0762626142.06", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0762626142.06"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "name": [
                "CeRePP, Hopital Tenon, Assistance Publique-Hopitaux de Paris, 75020, Paris, France"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Cussenot", 
            "givenName": "Olivier", 
            "id": "sg:person.013241233644.08", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013241233644.08"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Louisiana State University Health Sciences Center New Orleans", 
              "id": "https://www.grid.ac/institutes/grid.279863.1", 
              "name": [
                "Department of Genetics, Louisiana State University Health Sciences Center, 70112, New Orleans, LA, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Mandal", 
            "givenName": "Diptasri", 
            "id": "sg:person.01231257611.17", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01231257611.17"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Washington", 
              "id": "https://www.grid.ac/institutes/grid.34477.33", 
              "name": [
                "Department of Biostatistics, University of Washington, 98195, Seattle, WA, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Laurie", 
            "givenName": "Cecelia", 
            "id": "sg:person.015051420117.50", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015051420117.50"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Washington", 
              "id": "https://www.grid.ac/institutes/grid.34477.33", 
              "name": [
                "Department of Biostatistics, University of Washington, 98195, Seattle, WA, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Laurie", 
            "givenName": "Cathy", 
            "id": "sg:person.014254037517.83", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014254037517.83"
            ], 
            "type": "Person"
          }, 
          {
            "familyName": "The PRACTICAL consortium", 
            "type": "Person"
          }, 
          {
            "familyName": "International Consortium for Prostate Cancer Genetics", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Mayo Clinic", 
              "id": "https://www.grid.ac/institutes/grid.66875.3a", 
              "name": [
                "Department of Lab Medicine and Pathology, Mayo Clinic, 55905, Rochester, MN, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Thibodeau", 
            "givenName": "Stephen N.", 
            "id": "sg:person.011206006064.48", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011206006064.48"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Institute of Cancer Research", 
              "id": "https://www.grid.ac/institutes/grid.18886.3f", 
              "name": [
                "Division of Genetics and Epidemiology, Institute of Cancer Research, SW7 3RP, London, UK"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Eeles", 
            "givenName": "Rosalind A.", 
            "id": "sg:person.010370267737.55", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010370267737.55"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Institute of Cancer Research", 
              "id": "https://www.grid.ac/institutes/grid.18886.3f", 
              "name": [
                "Division of Genetics and Epidemiology, Institute of Cancer Research, SW7 3RP, London, UK"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Kote-Jarai", 
            "givenName": "Zsofia", 
            "id": "sg:person.01157661566.11", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01157661566.11"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "George E. Wahlen Department of VA Medical Center", 
              "id": "https://www.grid.ac/institutes/grid.413886.0", 
              "name": [
                "Department of Internal Medicine, University of Utah School of Medicine, 84108, Salt Lake City, UT, USA", 
                "George E. Wahlen Department of Veterans Affairs Medical Center, 84148, Salt Lake City, UT, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Cannon-Albright", 
            "givenName": "Lisa", 
            "id": "sg:person.0621671247.41", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0621671247.41"
            ], 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "sg:pub.10.1038/nature11632", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1000661742", 
              "https://doi.org/10.1038/nature11632"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.1400350111", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1000708053"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nmeth.1785", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002640757", 
              "https://doi.org/10.1038/nmeth.1785"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng.452", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003124418", 
              "https://doi.org/10.1038/ng.452"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng.452", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003124418", 
              "https://doi.org/10.1038/ng.452"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng2022", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003791570", 
              "https://doi.org/10.1038/ng2022"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng2022", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003791570", 
              "https://doi.org/10.1038/ng2022"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/nar/29.1.308", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1005817660"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng.882", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006950108", 
              "https://doi.org/10.1038/ng.882"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s13277-013-1157-5", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1007021967", 
              "https://doi.org/10.1007/s13277-013-1157-5"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng1808", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008387561", 
              "https://doi.org/10.1038/ng1808"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng1808", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008387561", 
              "https://doi.org/10.1038/ng1808"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/gepi.20303", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008645052"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ncomms7889", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1011227333", 
              "https://doi.org/10.1038/ncomms7889"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/bioinformatics/btp698", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1012031985"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/jnci/djm250", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1013631931"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/hmg/dds425", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1016105467"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng2015", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018455308", 
              "https://doi.org/10.1038/ng2015"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng2015", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018455308", 
              "https://doi.org/10.1038/ng2015"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1086/519795", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1019061180"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/nar/gkq603", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1020792304"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng.839", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021122270", 
              "https://doi.org/10.1038/ng.839"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng.2437", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1022658783", 
              "https://doi.org/10.1038/ng.2437"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng1999", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1023573468", 
              "https://doi.org/10.1038/ng1999"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng1999", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1023573468", 
              "https://doi.org/10.1038/ng1999"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00439-006-0219-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024641060", 
              "https://doi.org/10.1007/s00439-006-0219-9"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00439-006-0219-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024641060", 
              "https://doi.org/10.1007/s00439-006-0219-9"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00439-006-0219-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024641060", 
              "https://doi.org/10.1007/s00439-006-0219-9"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/pros.23008", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1026304378"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng.214", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1026972650", 
              "https://doi.org/10.1038/ng.214"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/bioinformatics/btu198", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1027097495"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng.3094", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1027844356", 
              "https://doi.org/10.1038/ng.3094"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1158/1055-9965.epi-08-0317", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1028148017"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1101/gr.107524.110", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1032096953"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.gde.2015.07.001", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1032104348"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/hmg/ddr295", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1032391731"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1467-9868.2011.01004.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1037593897"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1158/1078-0432.ccr-08-1822", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039132303"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1086/345310", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039137551"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1086/345310", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039137551"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/pros.20554", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039721829"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1158/1055-9965.epi-07-2811", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040721315"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrg2813", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043354004", 
              "https://doi.org/10.1038/nrg2813"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrg2813", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043354004", 
              "https://doi.org/10.1038/nrg2813"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1371/journal.pgen.1000529", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043446290"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1056/nejmoa1110000", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043805171"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/hmg/ddv203", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046680127"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/bioinformatics/btv690", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046684308"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00439-015-1534-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1047998074", 
              "https://doi.org/10.1007/s00439-015-1534-9"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00439-015-1534-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1047998074", 
              "https://doi.org/10.1007/s00439-015-1534-9"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng.90", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048595961", 
              "https://doi.org/10.1038/ng.90"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng.448", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048989600", 
              "https://doi.org/10.1038/ng.448"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng.448", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048989600", 
              "https://doi.org/10.1038/ng.448"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng2062", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049412903", 
              "https://doi.org/10.1038/ng2062"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/gepi.20516", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049458939"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/gepi.20516", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049458939"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng.2560", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049745027", 
              "https://doi.org/10.1038/ng.2560"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng.91", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1051674872", 
              "https://doi.org/10.1038/ng.91"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng.89", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1052903822", 
              "https://doi.org/10.1038/ng.89"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/jnci/djv431", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1059821632"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.18637/jss.v033.i01", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1068672496"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.18637/jss.v033.i01", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1068672496"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3892/or.2015.4364", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1071534091"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3892/or.2015.4364", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1071534091"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.4161/cc.23201", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1072297049"
            ], 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "2016-08", 
        "datePublishedReg": "2016-08-01", 
        "description": "Previous genome-wide association studies (GWAS) of prostate cancer risk focused on cases unselected for family history and have reported over 100 significant associations. The International Consortium for Prostate Cancer Genetics (ICPCG) has now performed a GWAS of 2511 (unrelated) familial prostate cancer cases and 1382 unaffected controls from 12 member sites. All samples were genotyped on the Illumina 5M+exome single nucleotide polymorphism (SNP) platform. The GWAS identified a significant evidence for association for SNPs in six regions previously associated with prostate cancer in population-based cohorts, including 3q26.2, 6q25.3, 8q24.21, 10q11.23, 11q13.3, and 17q12. Of note, SNP rs138042437 (p\u00a0=\u00a01.7e(-8)) at 8q24.21 achieved a large estimated effect size in this cohort (odds ratio\u00a0=\u00a013.3). 116 previously sampled affected relatives of 62 risk-allele carriers from the GWAS cohort were genotyped for this SNP, identifying 78 additional affected carriers in 62 pedigrees. A test for an excess number of affected carriers among relatives exhibited strong evidence for co-segregation of the variant with disease (p\u00a0=\u00a08.5e(-11)). The majority (92\u00a0%) of risk-allele carriers at rs138042437 had a consistent estimated haplotype spanning approximately 100\u00a0kb of 8q24.21 that contained the minor alleles of three rare SNPs (dosage minor allele frequencies <1.7\u00a0%), rs183373024 (PRNCR1), previously associated SNP rs188140481, and rs138042437 (CASC19). Strong evidence for co-segregation of a SNP on the haplotype further characterizes the haplotype as a prostate cancer predisposition locus.", 
        "genre": "research_article", 
        "id": "sg:pub.10.1007/s00439-016-1690-6", 
        "inLanguage": [
          "en"
        ], 
        "isAccessibleForFree": true, 
        "isFundedItemOf": [
          {
            "id": "sg:grant.2695966", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.5136722", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2471099", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2474042", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2695968", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2475725", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.5143529", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.3772173", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.5138083", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2695970", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.5140726", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.5135789", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2479403", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2438861", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.5140591", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2725727", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2688957", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.4242185", 
            "type": "MonetaryGrant"
          }
        ], 
        "isPartOf": [
          {
            "id": "sg:journal.1085982", 
            "issn": [
              "0340-6717", 
              "1432-1203"
            ], 
            "name": "Human Genetics", 
            "type": "Periodical"
          }, 
          {
            "issueNumber": "8", 
            "type": "PublicationIssue"
          }, 
          {
            "type": "PublicationVolume", 
            "volumeNumber": "135"
          }
        ], 
        "name": "Genome-wide association of familial prostate cancer cases identifies evidence for a rare segregating haplotype at 8q24.21", 
        "pagination": "923-938", 
        "productId": [
          {
            "name": "readcube_id", 
            "type": "PropertyValue", 
            "value": [
              "37153e69281d6a81a2b614d592ce3cd340bfa6203c6492906f29936f5d8b68e5"
            ]
          }, 
          {
            "name": "pubmed_id", 
            "type": "PropertyValue", 
            "value": [
              "27262462"
            ]
          }, 
          {
            "name": "nlm_unique_id", 
            "type": "PropertyValue", 
            "value": [
              "7613873"
            ]
          }, 
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1007/s00439-016-1690-6"
            ]
          }, 
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1011561241"
            ]
          }
        ], 
        "sameAs": [
          "https://doi.org/10.1007/s00439-016-1690-6", 
          "https://app.dimensions.ai/details/publication/pub.1011561241"
        ], 
        "sdDataset": "articles", 
        "sdDatePublished": "2019-04-11T12:24", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000362_0000000362/records_87097_00000000.jsonl", 
        "type": "ScholarlyArticle", 
        "url": "https://link.springer.com/10.1007%2Fs00439-016-1690-6"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00439-016-1690-6'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00439-016-1690-6'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00439-016-1690-6'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00439-016-1690-6'


     

    This table displays all metadata directly associated to this object as RDF triples.

    703 TRIPLES      21 PREDICATES      96 URIs      37 LITERALS      25 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1007/s00439-016-1690-6 schema:about N0c67fa6f5e3e488ea41bc51782899377
    2 N248a115e890b470bb3e8d94c404aca5d
    3 N2c3c3a43e09d4822a223ee60e69f3540
    4 N55491b7586f7465fb59621f4ba812694
    5 N6f8d795d42f943678c356bc889c3c64c
    6 N70786434a0a740c8ac46417923afafca
    7 N76a6859a30f842208064552ef252809c
    8 N7bab2700ad3540a7abe73068f186c96d
    9 N7d6ce2c8eef5400d8c0af5e9ad4dbc54
    10 N83175b9abfee430caaecdfebddd56a39
    11 N9c646d4f981b43599583e61d62684317
    12 Na1a58f5f4e1341959d8bd060c51ad623
    13 Nc1e88839a4fa4e39b460b1f78e85f11a
    14 Nd38580da1e6a42b7bfa4eb762b01d6e5
    15 Nf244f5e52ab24579a5e40b9eb7650e09
    16 Nfcdee97765b040f6baeba77ebc15a0e6
    17 anzsrc-for:11
    18 anzsrc-for:1112
    19 schema:author Nb26f0d28ad2d449bb76dfcbf625dcb38
    20 schema:citation sg:pub.10.1007/s00439-006-0219-9
    21 sg:pub.10.1007/s00439-015-1534-9
    22 sg:pub.10.1007/s13277-013-1157-5
    23 sg:pub.10.1038/nature11632
    24 sg:pub.10.1038/ncomms7889
    25 sg:pub.10.1038/ng.214
    26 sg:pub.10.1038/ng.2437
    27 sg:pub.10.1038/ng.2560
    28 sg:pub.10.1038/ng.3094
    29 sg:pub.10.1038/ng.448
    30 sg:pub.10.1038/ng.452
    31 sg:pub.10.1038/ng.839
    32 sg:pub.10.1038/ng.882
    33 sg:pub.10.1038/ng.89
    34 sg:pub.10.1038/ng.90
    35 sg:pub.10.1038/ng.91
    36 sg:pub.10.1038/ng1808
    37 sg:pub.10.1038/ng1999
    38 sg:pub.10.1038/ng2015
    39 sg:pub.10.1038/ng2022
    40 sg:pub.10.1038/ng2062
    41 sg:pub.10.1038/nmeth.1785
    42 sg:pub.10.1038/nrg2813
    43 https://doi.org/10.1002/gepi.20303
    44 https://doi.org/10.1002/gepi.20516
    45 https://doi.org/10.1002/pros.20554
    46 https://doi.org/10.1002/pros.23008
    47 https://doi.org/10.1016/j.gde.2015.07.001
    48 https://doi.org/10.1056/nejmoa1110000
    49 https://doi.org/10.1073/pnas.1400350111
    50 https://doi.org/10.1086/345310
    51 https://doi.org/10.1086/519795
    52 https://doi.org/10.1093/bioinformatics/btp698
    53 https://doi.org/10.1093/bioinformatics/btu198
    54 https://doi.org/10.1093/bioinformatics/btv690
    55 https://doi.org/10.1093/hmg/ddr295
    56 https://doi.org/10.1093/hmg/dds425
    57 https://doi.org/10.1093/hmg/ddv203
    58 https://doi.org/10.1093/jnci/djm250
    59 https://doi.org/10.1093/jnci/djv431
    60 https://doi.org/10.1093/nar/29.1.308
    61 https://doi.org/10.1093/nar/gkq603
    62 https://doi.org/10.1101/gr.107524.110
    63 https://doi.org/10.1111/j.1467-9868.2011.01004.x
    64 https://doi.org/10.1158/1055-9965.epi-07-2811
    65 https://doi.org/10.1158/1055-9965.epi-08-0317
    66 https://doi.org/10.1158/1078-0432.ccr-08-1822
    67 https://doi.org/10.1371/journal.pgen.1000529
    68 https://doi.org/10.18637/jss.v033.i01
    69 https://doi.org/10.3892/or.2015.4364
    70 https://doi.org/10.4161/cc.23201
    71 schema:datePublished 2016-08
    72 schema:datePublishedReg 2016-08-01
    73 schema:description Previous genome-wide association studies (GWAS) of prostate cancer risk focused on cases unselected for family history and have reported over 100 significant associations. The International Consortium for Prostate Cancer Genetics (ICPCG) has now performed a GWAS of 2511 (unrelated) familial prostate cancer cases and 1382 unaffected controls from 12 member sites. All samples were genotyped on the Illumina 5M+exome single nucleotide polymorphism (SNP) platform. The GWAS identified a significant evidence for association for SNPs in six regions previously associated with prostate cancer in population-based cohorts, including 3q26.2, 6q25.3, 8q24.21, 10q11.23, 11q13.3, and 17q12. Of note, SNP rs138042437 (p = 1.7e(-8)) at 8q24.21 achieved a large estimated effect size in this cohort (odds ratio = 13.3). 116 previously sampled affected relatives of 62 risk-allele carriers from the GWAS cohort were genotyped for this SNP, identifying 78 additional affected carriers in 62 pedigrees. A test for an excess number of affected carriers among relatives exhibited strong evidence for co-segregation of the variant with disease (p = 8.5e(-11)). The majority (92 %) of risk-allele carriers at rs138042437 had a consistent estimated haplotype spanning approximately 100 kb of 8q24.21 that contained the minor alleles of three rare SNPs (dosage minor allele frequencies <1.7 %), rs183373024 (PRNCR1), previously associated SNP rs188140481, and rs138042437 (CASC19). Strong evidence for co-segregation of a SNP on the haplotype further characterizes the haplotype as a prostate cancer predisposition locus.
    74 schema:genre research_article
    75 schema:inLanguage en
    76 schema:isAccessibleForFree true
    77 schema:isPartOf N35dc232ac9a247079cb31506e57b716d
    78 Nee1248f2543747c3850d47080213c908
    79 sg:journal.1085982
    80 schema:name Genome-wide association of familial prostate cancer cases identifies evidence for a rare segregating haplotype at 8q24.21
    81 schema:pagination 923-938
    82 schema:productId N40128a61540341b7a5ae430b5dfb97a5
    83 N58e2798fcd384c70ae8a42292d6958ec
    84 N6cba3bf86d994275957b9e66d7262f13
    85 Nb1e6d4cd91ac4b9a9d47263365dfbf70
    86 Nc8deca0af45d45f38ea877a9a0d9af78
    87 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011561241
    88 https://doi.org/10.1007/s00439-016-1690-6
    89 schema:sdDatePublished 2019-04-11T12:24
    90 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    91 schema:sdPublisher Na7f5925c245640e38e567b80d15f544a
    92 schema:url https://link.springer.com/10.1007%2Fs00439-016-1690-6
    93 sgo:license sg:explorer/license/
    94 sgo:sdDataset articles
    95 rdf:type schema:ScholarlyArticle
    96 N042f5bac5b7042f8a4471a127ceaf64f rdf:first sg:person.015660611161.08
    97 rdf:rest N41b102cdf9fc484194150cdc98961c63
    98 N0503c5ba1f48490ab5fdf3d3f2e0cb51 rdf:first sg:person.01145536753.98
    99 rdf:rest Nae85c3ad65b64a3c865e97412f697daf
    100 N050a3e1c96494544bab349d9c816d0ca rdf:first sg:person.0735116427.86
    101 rdf:rest Nd3cc51afd1b74cbfb436942adfd54967
    102 N061b953a795d43c2af99e43245e580e5 rdf:first sg:person.0750731602.70
    103 rdf:rest N83b7f703a01e4aaf8486172b438f9a07
    104 N0c67fa6f5e3e488ea41bc51782899377 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    105 schema:name Gene Frequency
    106 rdf:type schema:DefinedTerm
    107 N0e56eab8894142b78df5cfd1e9ba70d0 rdf:first sg:person.01355260210.43
    108 rdf:rest Nf1e91953910b4de898ff060877d143cf
    109 N1448257de32c49dfa0317d7b875d4644 rdf:first sg:person.0621671247.41
    110 rdf:rest rdf:nil
    111 N156161afbc674367b1af9448633e0723 rdf:first Ndb2fbc5d878d4e1abdbb28232d9c5116
    112 rdf:rest N3a86f0f1e4c94706a7ee09f27bc196c9
    113 N15dc6ce1f0914974ad445b3fb45e6beb rdf:first sg:person.012350263567.50
    114 rdf:rest N1e969aa174354cca8bbaf58d9c378d50
    115 N1e969aa174354cca8bbaf58d9c378d50 rdf:first sg:person.01257674522.66
    116 rdf:rest N061b953a795d43c2af99e43245e580e5
    117 N1f6da6d3953b499c98023a8a20fda51b rdf:first Ne2f0637905a940679471964237ddc430
    118 rdf:rest N0503c5ba1f48490ab5fdf3d3f2e0cb51
    119 N248a115e890b470bb3e8d94c404aca5d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    120 schema:name Risk Factors
    121 rdf:type schema:DefinedTerm
    122 N282a68e928c640aeb8a3dea972c36277 rdf:first sg:person.015051420117.50
    123 rdf:rest Nc8d4a3d211b04e8fa7106be3abd0fb42
    124 N2c3c3a43e09d4822a223ee60e69f3540 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    125 schema:name Prostatic Neoplasms
    126 rdf:type schema:DefinedTerm
    127 N35dc232ac9a247079cb31506e57b716d schema:volumeNumber 135
    128 rdf:type schema:PublicationVolume
    129 N38ca1bc40fbd4d9b87cefa6dede456ac rdf:first sg:person.0732505060.44
    130 rdf:rest Na8a04bf39ec74fd3be96ee57227e5940
    131 N3a86f0f1e4c94706a7ee09f27bc196c9 rdf:first sg:person.011206006064.48
    132 rdf:rest N7a76d015194c4aadaf9b4a407dbd5de8
    133 N40128a61540341b7a5ae430b5dfb97a5 schema:name dimensions_id
    134 schema:value pub.1011561241
    135 rdf:type schema:PropertyValue
    136 N41b102cdf9fc484194150cdc98961c63 rdf:first sg:person.01123520621.15
    137 rdf:rest Na664804bdcb74ba897a30976cb70a729
    138 N4635864ee67c426bbd74c5a08b761c36 schema:affiliation https://www.grid.ac/institutes/grid.21107.35
    139 schema:familyName Wiley
    140 schema:givenName Kathleen E.
    141 rdf:type schema:Person
    142 N497c2d2bafd3480aad4a2b62838da1f6 rdf:first sg:person.01003416206.40
    143 rdf:rest N6333a5c77a574c6ea2491953e7dc05da
    144 N55491b7586f7465fb59621f4ba812694 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    145 schema:name Genotype
    146 rdf:type schema:DefinedTerm
    147 N58e2798fcd384c70ae8a42292d6958ec schema:name readcube_id
    148 schema:value 37153e69281d6a81a2b614d592ce3cd340bfa6203c6492906f29936f5d8b68e5
    149 rdf:type schema:PropertyValue
    150 N6333a5c77a574c6ea2491953e7dc05da rdf:first sg:person.01237602223.31
    151 rdf:rest N15dc6ce1f0914974ad445b3fb45e6beb
    152 N66557162ced74eaabb6df2c136dea429 rdf:first sg:person.013241233644.08
    153 rdf:rest Ne6b52b8686134c21a95b360ac94f5690
    154 N6cba3bf86d994275957b9e66d7262f13 schema:name pubmed_id
    155 schema:value 27262462
    156 rdf:type schema:PropertyValue
    157 N6f8d795d42f943678c356bc889c3c64c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    158 schema:name Genetic Predisposition to Disease
    159 rdf:type schema:DefinedTerm
    160 N70786434a0a740c8ac46417923afafca schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    161 schema:name Haplotypes
    162 rdf:type schema:DefinedTerm
    163 N76a6859a30f842208064552ef252809c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    164 schema:name Aged
    165 rdf:type schema:DefinedTerm
    166 N79dfea72eaa2438da7ccda976bb9aec8 rdf:first Nca976d8eef5149798c9336e874bb41c0
    167 rdf:rest Na95adede54b74d2fbba756bcd0ee662c
    168 N7a76d015194c4aadaf9b4a407dbd5de8 rdf:first sg:person.010370267737.55
    169 rdf:rest Naef5b78d48044681b1557757f3153fb0
    170 N7bab2700ad3540a7abe73068f186c96d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    171 schema:name Pedigree
    172 rdf:type schema:DefinedTerm
    173 N7d6ce2c8eef5400d8c0af5e9ad4dbc54 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    174 schema:name Humans
    175 rdf:type schema:DefinedTerm
    176 N83175b9abfee430caaecdfebddd56a39 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    177 schema:name Male
    178 rdf:type schema:DefinedTerm
    179 N83b7f703a01e4aaf8486172b438f9a07 rdf:first sg:person.01177163404.55
    180 rdf:rest N79dfea72eaa2438da7ccda976bb9aec8
    181 N899a4981c0964cafa4220bed3410358b schema:name CeRePP, Hopital Tenon, Assistance Publique-Hopitaux de Paris, 75020, Paris, France
    182 rdf:type schema:Organization
    183 N89cd1733126045bb9796b46ae7115004 rdf:first sg:person.013347276237.81
    184 rdf:rest N042f5bac5b7042f8a4471a127ceaf64f
    185 N94c9d0965df9478a8c7140fcbb1c3fda rdf:first sg:person.0721307601.00
    186 rdf:rest Nd5504191dd81455a8b3fb7a65de1cd16
    187 N954a2c44e8c6401ead43fbffedb1e01d schema:name CeRePP, Hopital Tenon, Assistance Publique-Hopitaux de Paris, 75020, Paris, France
    188 rdf:type schema:Organization
    189 N9b586c00dc4845efbf08f79543afb4c8 rdf:first Ncc76f647a1c649b5b7e09bf632f811ec
    190 rdf:rest N156161afbc674367b1af9448633e0723
    191 N9c646d4f981b43599583e61d62684317 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    192 schema:name Middle Aged
    193 rdf:type schema:DefinedTerm
    194 Na1a58f5f4e1341959d8bd060c51ad623 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    195 schema:name Heterozygote
    196 rdf:type schema:DefinedTerm
    197 Na664804bdcb74ba897a30976cb70a729 rdf:first sg:person.0701403642.35
    198 rdf:rest N050a3e1c96494544bab349d9c816d0ca
    199 Na6b5a8e706b847858bc490e0e6300a55 rdf:first sg:person.0762626142.06
    200 rdf:rest N66557162ced74eaabb6df2c136dea429
    201 Na7f5925c245640e38e567b80d15f544a schema:name Springer Nature - SN SciGraph project
    202 rdf:type schema:Organization
    203 Na8a04bf39ec74fd3be96ee57227e5940 rdf:first sg:person.014514614637.17
    204 rdf:rest Nc468603e2a054402ab24a52eef153dc4
    205 Na95adede54b74d2fbba756bcd0ee662c rdf:first sg:person.01170256773.00
    206 rdf:rest Nf0c258e167c94465a5bf3e941edc4a17
    207 Nae85c3ad65b64a3c865e97412f697daf rdf:first Nc043aed604e5453da68d1ded699abf6a
    208 rdf:rest Na6b5a8e706b847858bc490e0e6300a55
    209 Naef5b78d48044681b1557757f3153fb0 rdf:first sg:person.01157661566.11
    210 rdf:rest N1448257de32c49dfa0317d7b875d4644
    211 Nb1e6d4cd91ac4b9a9d47263365dfbf70 schema:name doi
    212 schema:value 10.1007/s00439-016-1690-6
    213 rdf:type schema:PropertyValue
    214 Nb26f0d28ad2d449bb76dfcbf625dcb38 rdf:first sg:person.01016504312.27
    215 rdf:rest Nfd64249e169a49a19b63a80244e1ff7e
    216 Nb30e704c3d664845a9e250e2365d29db rdf:first sg:person.01340276667.21
    217 rdf:rest N38ca1bc40fbd4d9b87cefa6dede456ac
    218 Nb5f001bca6d94fe5990634a0e12cbf5f schema:affiliation https://www.grid.ac/institutes/grid.6582.9
    219 schema:familyName Maier
    220 schema:givenName Christiane
    221 rdf:type schema:Person
    222 Nb7766ca9df164da6a16e470b9beae01a rdf:first sg:person.01241031610.88
    223 rdf:rest Nb30e704c3d664845a9e250e2365d29db
    224 Nc043aed604e5453da68d1ded699abf6a schema:affiliation https://www.grid.ac/institutes/grid.240372.0
    225 schema:familyName Xu
    226 schema:givenName Jianfeng
    227 rdf:type schema:Person
    228 Nc1e88839a4fa4e39b460b1f78e85f11a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    229 schema:name Tumor Suppressor Proteins
    230 rdf:type schema:DefinedTerm
    231 Nc468603e2a054402ab24a52eef153dc4 rdf:first sg:person.01116216607.59
    232 rdf:rest N94c9d0965df9478a8c7140fcbb1c3fda
    233 Nc8d4a3d211b04e8fa7106be3abd0fb42 rdf:first sg:person.014254037517.83
    234 rdf:rest N9b586c00dc4845efbf08f79543afb4c8
    235 Nc8deca0af45d45f38ea877a9a0d9af78 schema:name nlm_unique_id
    236 schema:value 7613873
    237 rdf:type schema:PropertyValue
    238 Nca976d8eef5149798c9336e874bb41c0 schema:affiliation https://www.grid.ac/institutes/grid.66875.3a
    239 schema:familyName Schaid
    240 schema:givenName Daniel J.
    241 rdf:type schema:Person
    242 Ncc6e29fd97d8484594b2045d8a7558ca rdf:first Nb5f001bca6d94fe5990634a0e12cbf5f
    243 rdf:rest Nd3198ffc7bf143a0bd94b8d2ba3fe794
    244 Ncc76f647a1c649b5b7e09bf632f811ec schema:familyName The PRACTICAL consortium
    245 rdf:type schema:Person
    246 Nd3198ffc7bf143a0bd94b8d2ba3fe794 rdf:first sg:person.0623267507.88
    247 rdf:rest N89cd1733126045bb9796b46ae7115004
    248 Nd38580da1e6a42b7bfa4eb762b01d6e5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    249 schema:name Genome-Wide Association Study
    250 rdf:type schema:DefinedTerm
    251 Nd3cc51afd1b74cbfb436942adfd54967 rdf:first N4635864ee67c426bbd74c5a08b761c36
    252 rdf:rest Ne0494e517cce4fbc83b58964b1f3a7a3
    253 Nd5504191dd81455a8b3fb7a65de1cd16 rdf:first sg:person.01215575561.02
    254 rdf:rest Ncc6e29fd97d8484594b2045d8a7558ca
    255 Ndb2fbc5d878d4e1abdbb28232d9c5116 schema:familyName International Consortium for Prostate Cancer Genetics
    256 rdf:type schema:Person
    257 Ne0494e517cce4fbc83b58964b1f3a7a3 rdf:first sg:person.010145071237.85
    258 rdf:rest N1f6da6d3953b499c98023a8a20fda51b
    259 Ne2f0637905a940679471964237ddc430 schema:affiliation https://www.grid.ac/institutes/grid.21107.35
    260 schema:familyName Walsh
    261 schema:givenName Patrick C.
    262 rdf:type schema:Person
    263 Ne6b52b8686134c21a95b360ac94f5690 rdf:first sg:person.01231257611.17
    264 rdf:rest N282a68e928c640aeb8a3dea972c36277
    265 Nee1248f2543747c3850d47080213c908 schema:issueNumber 8
    266 rdf:type schema:PublicationIssue
    267 Nf0c258e167c94465a5bf3e941edc4a17 rdf:first sg:person.014056437627.94
    268 rdf:rest N0e56eab8894142b78df5cfd1e9ba70d0
    269 Nf1e91953910b4de898ff060877d143cf rdf:first sg:person.01113677032.85
    270 rdf:rest Nb7766ca9df164da6a16e470b9beae01a
    271 Nf244f5e52ab24579a5e40b9eb7650e09 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    272 schema:name RNA, Long Noncoding
    273 rdf:type schema:DefinedTerm
    274 Nfcdee97765b040f6baeba77ebc15a0e6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    275 schema:name Polymorphism, Single Nucleotide
    276 rdf:type schema:DefinedTerm
    277 Nfd64249e169a49a19b63a80244e1ff7e rdf:first sg:person.01070241414.27
    278 rdf:rest N497c2d2bafd3480aad4a2b62838da1f6
    279 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
    280 schema:name Medical and Health Sciences
    281 rdf:type schema:DefinedTerm
    282 anzsrc-for:1112 schema:inDefinedTermSet anzsrc-for:
    283 schema:name Oncology and Carcinogenesis
    284 rdf:type schema:DefinedTerm
    285 sg:grant.2438861 http://pending.schema.org/fundedItem sg:pub.10.1007/s00439-016-1690-6
    286 rdf:type schema:MonetaryGrant
    287 sg:grant.2471099 http://pending.schema.org/fundedItem sg:pub.10.1007/s00439-016-1690-6
    288 rdf:type schema:MonetaryGrant
    289 sg:grant.2474042 http://pending.schema.org/fundedItem sg:pub.10.1007/s00439-016-1690-6
    290 rdf:type schema:MonetaryGrant
    291 sg:grant.2475725 http://pending.schema.org/fundedItem sg:pub.10.1007/s00439-016-1690-6
    292 rdf:type schema:MonetaryGrant
    293 sg:grant.2479403 http://pending.schema.org/fundedItem sg:pub.10.1007/s00439-016-1690-6
    294 rdf:type schema:MonetaryGrant
    295 sg:grant.2688957 http://pending.schema.org/fundedItem sg:pub.10.1007/s00439-016-1690-6
    296 rdf:type schema:MonetaryGrant
    297 sg:grant.2695966 http://pending.schema.org/fundedItem sg:pub.10.1007/s00439-016-1690-6
    298 rdf:type schema:MonetaryGrant
    299 sg:grant.2695968 http://pending.schema.org/fundedItem sg:pub.10.1007/s00439-016-1690-6
    300 rdf:type schema:MonetaryGrant
    301 sg:grant.2695970 http://pending.schema.org/fundedItem sg:pub.10.1007/s00439-016-1690-6
    302 rdf:type schema:MonetaryGrant
    303 sg:grant.2725727 http://pending.schema.org/fundedItem sg:pub.10.1007/s00439-016-1690-6
    304 rdf:type schema:MonetaryGrant
    305 sg:grant.3772173 http://pending.schema.org/fundedItem sg:pub.10.1007/s00439-016-1690-6
    306 rdf:type schema:MonetaryGrant
    307 sg:grant.4242185 http://pending.schema.org/fundedItem sg:pub.10.1007/s00439-016-1690-6
    308 rdf:type schema:MonetaryGrant
    309 sg:grant.5135789 http://pending.schema.org/fundedItem sg:pub.10.1007/s00439-016-1690-6
    310 rdf:type schema:MonetaryGrant
    311 sg:grant.5136722 http://pending.schema.org/fundedItem sg:pub.10.1007/s00439-016-1690-6
    312 rdf:type schema:MonetaryGrant
    313 sg:grant.5138083 http://pending.schema.org/fundedItem sg:pub.10.1007/s00439-016-1690-6
    314 rdf:type schema:MonetaryGrant
    315 sg:grant.5140591 http://pending.schema.org/fundedItem sg:pub.10.1007/s00439-016-1690-6
    316 rdf:type schema:MonetaryGrant
    317 sg:grant.5140726 http://pending.schema.org/fundedItem sg:pub.10.1007/s00439-016-1690-6
    318 rdf:type schema:MonetaryGrant
    319 sg:grant.5143529 http://pending.schema.org/fundedItem sg:pub.10.1007/s00439-016-1690-6
    320 rdf:type schema:MonetaryGrant
    321 sg:journal.1085982 schema:issn 0340-6717
    322 1432-1203
    323 schema:name Human Genetics
    324 rdf:type schema:Periodical
    325 sg:person.01003416206.40 schema:affiliation https://www.grid.ac/institutes/grid.18886.3f
    326 schema:familyName Dadaev
    327 schema:givenName Tokhir
    328 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01003416206.40
    329 rdf:type schema:Person
    330 sg:person.010145071237.85 schema:affiliation https://www.grid.ac/institutes/grid.21107.35
    331 schema:familyName Isaacs
    332 schema:givenName Sarah D.
    333 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010145071237.85
    334 rdf:type schema:Person
    335 sg:person.01016504312.27 schema:affiliation https://www.grid.ac/institutes/grid.223827.e
    336 schema:familyName Teerlink
    337 schema:givenName Craig C.
    338 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01016504312.27
    339 rdf:type schema:Person
    340 sg:person.010370267737.55 schema:affiliation https://www.grid.ac/institutes/grid.18886.3f
    341 schema:familyName Eeles
    342 schema:givenName Rosalind A.
    343 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010370267737.55
    344 rdf:type schema:Person
    345 sg:person.01070241414.27 schema:affiliation https://www.grid.ac/institutes/grid.18886.3f
    346 schema:familyName Leongamornlert
    347 schema:givenName Daniel
    348 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01070241414.27
    349 rdf:type schema:Person
    350 sg:person.01113677032.85 schema:affiliation https://www.grid.ac/institutes/grid.214458.e
    351 schema:familyName Ray
    352 schema:givenName Anna M.
    353 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01113677032.85
    354 rdf:type schema:Person
    355 sg:person.01116216607.59 schema:affiliation https://www.grid.ac/institutes/grid.3263.4
    356 schema:familyName Fitzgerald
    357 schema:givenName Liesel M.
    358 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01116216607.59
    359 rdf:type schema:Person
    360 sg:person.011206006064.48 schema:affiliation https://www.grid.ac/institutes/grid.66875.3a
    361 schema:familyName Thibodeau
    362 schema:givenName Stephen N.
    363 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011206006064.48
    364 rdf:type schema:Person
    365 sg:person.01123520621.15 schema:affiliation https://www.grid.ac/institutes/grid.1374.1
    366 schema:familyName Sipeky
    367 schema:givenName Csilla
    368 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01123520621.15
    369 rdf:type schema:Person
    370 sg:person.01145536753.98 schema:affiliation https://www.grid.ac/institutes/grid.21107.35
    371 schema:familyName Isaacs
    372 schema:givenName William B.
    373 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01145536753.98
    374 rdf:type schema:Person
    375 sg:person.01157661566.11 schema:affiliation https://www.grid.ac/institutes/grid.18886.3f
    376 schema:familyName Kote-Jarai
    377 schema:givenName Zsofia
    378 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01157661566.11
    379 rdf:type schema:Person
    380 sg:person.01170256773.00 schema:affiliation https://www.grid.ac/institutes/grid.16753.36
    381 schema:familyName Catalona
    382 schema:givenName William J.
    383 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01170256773.00
    384 rdf:type schema:Person
    385 sg:person.01177163404.55 schema:affiliation https://www.grid.ac/institutes/grid.66875.3a
    386 schema:familyName McDonnell
    387 schema:givenName Shannon K.
    388 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01177163404.55
    389 rdf:type schema:Person
    390 sg:person.01215575561.02 schema:affiliation https://www.grid.ac/institutes/grid.410712.1
    391 schema:familyName Luedeke
    392 schema:givenName Manuel
    393 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01215575561.02
    394 rdf:type schema:Person
    395 sg:person.01231257611.17 schema:affiliation https://www.grid.ac/institutes/grid.279863.1
    396 schema:familyName Mandal
    397 schema:givenName Diptasri
    398 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01231257611.17
    399 rdf:type schema:Person
    400 sg:person.012350263567.50 schema:affiliation https://www.grid.ac/institutes/grid.223827.e
    401 schema:familyName Farnham
    402 schema:givenName James
    403 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012350263567.50
    404 rdf:type schema:Person
    405 sg:person.01237602223.31 schema:affiliation https://www.grid.ac/institutes/grid.223827.e
    406 schema:familyName Thomas
    407 schema:givenName Alun
    408 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01237602223.31
    409 rdf:type schema:Person
    410 sg:person.01241031610.88 schema:affiliation https://www.grid.ac/institutes/grid.214458.e
    411 schema:familyName Zuhlke
    412 schema:givenName Kimberly A.
    413 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01241031610.88
    414 rdf:type schema:Person
    415 sg:person.01257674522.66 schema:affiliation https://www.grid.ac/institutes/grid.412722.0
    416 schema:familyName Stephenson
    417 schema:givenName Robert A.
    418 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01257674522.66
    419 rdf:type schema:Person
    420 sg:person.013241233644.08 schema:affiliation N899a4981c0964cafa4220bed3410358b
    421 schema:familyName Cussenot
    422 schema:givenName Olivier
    423 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013241233644.08
    424 rdf:type schema:Person
    425 sg:person.013347276237.81 schema:affiliation https://www.grid.ac/institutes/grid.280128.1
    426 schema:familyName Ostrander
    427 schema:givenName Elaine A.
    428 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013347276237.81
    429 rdf:type schema:Person
    430 sg:person.01340276667.21 schema:affiliation https://www.grid.ac/institutes/grid.410711.2
    431 schema:familyName Lange
    432 schema:givenName Ethan M.
    433 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01340276667.21
    434 rdf:type schema:Person
    435 sg:person.01355260210.43 schema:affiliation https://www.grid.ac/institutes/grid.214458.e
    436 schema:familyName Cooney
    437 schema:givenName Kathleen A.
    438 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01355260210.43
    439 rdf:type schema:Person
    440 sg:person.014056437627.94 schema:affiliation https://www.grid.ac/institutes/grid.16753.36
    441 schema:familyName Zheng
    442 schema:givenName S. Lilly
    443 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014056437627.94
    444 rdf:type schema:Person
    445 sg:person.014254037517.83 schema:affiliation https://www.grid.ac/institutes/grid.34477.33
    446 schema:familyName Laurie
    447 schema:givenName Cathy
    448 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014254037517.83
    449 rdf:type schema:Person
    450 sg:person.014514614637.17 schema:affiliation https://www.grid.ac/institutes/grid.1008.9
    451 schema:familyName Southey
    452 schema:givenName Melissa C.
    453 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014514614637.17
    454 rdf:type schema:Person
    455 sg:person.015051420117.50 schema:affiliation https://www.grid.ac/institutes/grid.34477.33
    456 schema:familyName Laurie
    457 schema:givenName Cecelia
    458 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015051420117.50
    459 rdf:type schema:Person
    460 sg:person.015660611161.08 schema:affiliation https://www.grid.ac/institutes/grid.1374.1
    461 schema:familyName Kaikkonen
    462 schema:givenName Elina M.
    463 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015660611161.08
    464 rdf:type schema:Person
    465 sg:person.0621671247.41 schema:affiliation https://www.grid.ac/institutes/grid.413886.0
    466 schema:familyName Cannon-Albright
    467 schema:givenName Lisa
    468 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0621671247.41
    469 rdf:type schema:Person
    470 sg:person.0623267507.88 schema:affiliation https://www.grid.ac/institutes/grid.270240.3
    471 schema:familyName Stanford
    472 schema:givenName Janet L.
    473 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0623267507.88
    474 rdf:type schema:Person
    475 sg:person.0701403642.35 schema:affiliation https://www.grid.ac/institutes/grid.412330.7
    476 schema:familyName Tammela
    477 schema:givenName Teuvo
    478 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0701403642.35
    479 rdf:type schema:Person
    480 sg:person.0721307601.00 schema:affiliation https://www.grid.ac/institutes/grid.410712.1
    481 schema:familyName Rinckleb
    482 schema:givenName Antje
    483 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0721307601.00
    484 rdf:type schema:Person
    485 sg:person.0732505060.44 schema:affiliation https://www.grid.ac/institutes/grid.1002.3
    486 schema:familyName Giles
    487 schema:givenName Graham G.
    488 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0732505060.44
    489 rdf:type schema:Person
    490 sg:person.0735116427.86 schema:affiliation https://www.grid.ac/institutes/grid.410552.7
    491 schema:familyName Schleutker
    492 schema:givenName Johanna
    493 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0735116427.86
    494 rdf:type schema:Person
    495 sg:person.0750731602.70 schema:affiliation https://www.grid.ac/institutes/grid.66875.3a
    496 schema:familyName Riska
    497 schema:givenName Shaun
    498 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0750731602.70
    499 rdf:type schema:Person
    500 sg:person.0762626142.06 schema:affiliation N954a2c44e8c6401ead43fbffedb1e01d
    501 schema:familyName Cancel-Tassin
    502 schema:givenName Geraldine
    503 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0762626142.06
    504 rdf:type schema:Person
    505 sg:pub.10.1007/s00439-006-0219-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024641060
    506 https://doi.org/10.1007/s00439-006-0219-9
    507 rdf:type schema:CreativeWork
    508 sg:pub.10.1007/s00439-015-1534-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047998074
    509 https://doi.org/10.1007/s00439-015-1534-9
    510 rdf:type schema:CreativeWork
    511 sg:pub.10.1007/s13277-013-1157-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007021967
    512 https://doi.org/10.1007/s13277-013-1157-5
    513 rdf:type schema:CreativeWork
    514 sg:pub.10.1038/nature11632 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000661742
    515 https://doi.org/10.1038/nature11632
    516 rdf:type schema:CreativeWork
    517 sg:pub.10.1038/ncomms7889 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011227333
    518 https://doi.org/10.1038/ncomms7889
    519 rdf:type schema:CreativeWork
    520 sg:pub.10.1038/ng.214 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026972650
    521 https://doi.org/10.1038/ng.214
    522 rdf:type schema:CreativeWork
    523 sg:pub.10.1038/ng.2437 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022658783
    524 https://doi.org/10.1038/ng.2437
    525 rdf:type schema:CreativeWork
    526 sg:pub.10.1038/ng.2560 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049745027
    527 https://doi.org/10.1038/ng.2560
    528 rdf:type schema:CreativeWork
    529 sg:pub.10.1038/ng.3094 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027844356
    530 https://doi.org/10.1038/ng.3094
    531 rdf:type schema:CreativeWork
    532 sg:pub.10.1038/ng.448 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048989600
    533 https://doi.org/10.1038/ng.448
    534 rdf:type schema:CreativeWork
    535 sg:pub.10.1038/ng.452 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003124418
    536 https://doi.org/10.1038/ng.452
    537 rdf:type schema:CreativeWork
    538 sg:pub.10.1038/ng.839 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021122270
    539 https://doi.org/10.1038/ng.839
    540 rdf:type schema:CreativeWork
    541 sg:pub.10.1038/ng.882 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006950108
    542 https://doi.org/10.1038/ng.882
    543 rdf:type schema:CreativeWork
    544 sg:pub.10.1038/ng.89 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052903822
    545 https://doi.org/10.1038/ng.89
    546 rdf:type schema:CreativeWork
    547 sg:pub.10.1038/ng.90 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048595961
    548 https://doi.org/10.1038/ng.90
    549 rdf:type schema:CreativeWork
    550 sg:pub.10.1038/ng.91 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051674872
    551 https://doi.org/10.1038/ng.91
    552 rdf:type schema:CreativeWork
    553 sg:pub.10.1038/ng1808 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008387561
    554 https://doi.org/10.1038/ng1808
    555 rdf:type schema:CreativeWork
    556 sg:pub.10.1038/ng1999 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023573468
    557 https://doi.org/10.1038/ng1999
    558 rdf:type schema:CreativeWork
    559 sg:pub.10.1038/ng2015 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018455308
    560 https://doi.org/10.1038/ng2015
    561 rdf:type schema:CreativeWork
    562 sg:pub.10.1038/ng2022 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003791570
    563 https://doi.org/10.1038/ng2022
    564 rdf:type schema:CreativeWork
    565 sg:pub.10.1038/ng2062 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049412903
    566 https://doi.org/10.1038/ng2062
    567 rdf:type schema:CreativeWork
    568 sg:pub.10.1038/nmeth.1785 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002640757
    569 https://doi.org/10.1038/nmeth.1785
    570 rdf:type schema:CreativeWork
    571 sg:pub.10.1038/nrg2813 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043354004
    572 https://doi.org/10.1038/nrg2813
    573 rdf:type schema:CreativeWork
    574 https://doi.org/10.1002/gepi.20303 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008645052
    575 rdf:type schema:CreativeWork
    576 https://doi.org/10.1002/gepi.20516 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049458939
    577 rdf:type schema:CreativeWork
    578 https://doi.org/10.1002/pros.20554 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039721829
    579 rdf:type schema:CreativeWork
    580 https://doi.org/10.1002/pros.23008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026304378
    581 rdf:type schema:CreativeWork
    582 https://doi.org/10.1016/j.gde.2015.07.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032104348
    583 rdf:type schema:CreativeWork
    584 https://doi.org/10.1056/nejmoa1110000 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043805171
    585 rdf:type schema:CreativeWork
    586 https://doi.org/10.1073/pnas.1400350111 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000708053
    587 rdf:type schema:CreativeWork
    588 https://doi.org/10.1086/345310 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039137551
    589 rdf:type schema:CreativeWork
    590 https://doi.org/10.1086/519795 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019061180
    591 rdf:type schema:CreativeWork
    592 https://doi.org/10.1093/bioinformatics/btp698 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012031985
    593 rdf:type schema:CreativeWork
    594 https://doi.org/10.1093/bioinformatics/btu198 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027097495
    595 rdf:type schema:CreativeWork
    596 https://doi.org/10.1093/bioinformatics/btv690 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046684308
    597 rdf:type schema:CreativeWork
    598 https://doi.org/10.1093/hmg/ddr295 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032391731
    599 rdf:type schema:CreativeWork
    600 https://doi.org/10.1093/hmg/dds425 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016105467
    601 rdf:type schema:CreativeWork
    602 https://doi.org/10.1093/hmg/ddv203 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046680127
    603 rdf:type schema:CreativeWork
    604 https://doi.org/10.1093/jnci/djm250 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013631931
    605 rdf:type schema:CreativeWork
    606 https://doi.org/10.1093/jnci/djv431 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059821632
    607 rdf:type schema:CreativeWork
    608 https://doi.org/10.1093/nar/29.1.308 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005817660
    609 rdf:type schema:CreativeWork
    610 https://doi.org/10.1093/nar/gkq603 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020792304
    611 rdf:type schema:CreativeWork
    612 https://doi.org/10.1101/gr.107524.110 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032096953
    613 rdf:type schema:CreativeWork
    614 https://doi.org/10.1111/j.1467-9868.2011.01004.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1037593897
    615 rdf:type schema:CreativeWork
    616 https://doi.org/10.1158/1055-9965.epi-07-2811 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040721315
    617 rdf:type schema:CreativeWork
    618 https://doi.org/10.1158/1055-9965.epi-08-0317 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028148017
    619 rdf:type schema:CreativeWork
    620 https://doi.org/10.1158/1078-0432.ccr-08-1822 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039132303
    621 rdf:type schema:CreativeWork
    622 https://doi.org/10.1371/journal.pgen.1000529 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043446290
    623 rdf:type schema:CreativeWork
    624 https://doi.org/10.18637/jss.v033.i01 schema:sameAs https://app.dimensions.ai/details/publication/pub.1068672496
    625 rdf:type schema:CreativeWork
    626 https://doi.org/10.3892/or.2015.4364 schema:sameAs https://app.dimensions.ai/details/publication/pub.1071534091
    627 rdf:type schema:CreativeWork
    628 https://doi.org/10.4161/cc.23201 schema:sameAs https://app.dimensions.ai/details/publication/pub.1072297049
    629 rdf:type schema:CreativeWork
    630 https://www.grid.ac/institutes/grid.1002.3 schema:alternateName Monash University
    631 schema:name Cancer Epidemiology Centre, Cancer Council Victoria, 3004, Melbourne, Australia
    632 Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, 3010, Melbourne, VIC, Australia
    633 Department of Epidemiology and Preventive Medicine, Monash University, 3004, Melbourne, VIC, Australia
    634 rdf:type schema:Organization
    635 https://www.grid.ac/institutes/grid.1008.9 schema:alternateName University of Melbourne
    636 schema:name Department of Pathology, University of Melbourne, 3010, Melbourne, Australia
    637 rdf:type schema:Organization
    638 https://www.grid.ac/institutes/grid.1374.1 schema:alternateName University of Turku
    639 schema:name Department of Medical Biochemistry and Genetics, University of Turku, 20520, Turku, Finland
    640 rdf:type schema:Organization
    641 https://www.grid.ac/institutes/grid.16753.36 schema:alternateName Northwestern University
    642 schema:name Feinberg School of Medicine, Northwestern University, 60611, Chicago, IL, USA
    643 rdf:type schema:Organization
    644 https://www.grid.ac/institutes/grid.18886.3f schema:alternateName Institute of Cancer Research
    645 schema:name Division of Genetics and Epidemiology, Institute of Cancer Research, SW7 3RP, London, UK
    646 rdf:type schema:Organization
    647 https://www.grid.ac/institutes/grid.21107.35 schema:alternateName Johns Hopkins University
    648 schema:name Brady Urological Institute, Johns Hopkins University, 21287, Baltimore, MD, USA
    649 rdf:type schema:Organization
    650 https://www.grid.ac/institutes/grid.214458.e schema:alternateName University of Michigan–Ann Arbor
    651 schema:name Department of Internal Medicine, University of Michigan Medical School, 48109, Ann Arbor, MI, USA
    652 Department of Urology, University of Michigan Medical School, 48109, Ann Arbor, MI, USA
    653 rdf:type schema:Organization
    654 https://www.grid.ac/institutes/grid.223827.e schema:alternateName University of Utah
    655 schema:name Department of Internal Medicine, University of Utah School of Medicine, 84108, Salt Lake City, UT, USA
    656 rdf:type schema:Organization
    657 https://www.grid.ac/institutes/grid.240372.0 schema:alternateName NorthShore University HealthSystem
    658 schema:name Program for Personalized Cancer Care, NorthShore University Health System, 60201, Evanston, IL, USA
    659 rdf:type schema:Organization
    660 https://www.grid.ac/institutes/grid.270240.3 schema:alternateName Fred Hutchinson Cancer Research Center
    661 schema:name Division of Public Health Sciences, Fred Hutchinson Cancer Research Center (FHCRC), 98109, Seattle, WA, USA
    662 rdf:type schema:Organization
    663 https://www.grid.ac/institutes/grid.279863.1 schema:alternateName Louisiana State University Health Sciences Center New Orleans
    664 schema:name Department of Genetics, Louisiana State University Health Sciences Center, 70112, New Orleans, LA, USA
    665 rdf:type schema:Organization
    666 https://www.grid.ac/institutes/grid.280128.1 schema:alternateName National Human Genome Research Institute
    667 schema:name Cancer Genetics Branch, National Human Genome Research Institute (NHGRI), National Institutes of Health (NIH), 20892, Bethesda, MD, USA
    668 rdf:type schema:Organization
    669 https://www.grid.ac/institutes/grid.3263.4 schema:alternateName Cancer Council Victoria
    670 schema:name Cancer Epidemiology Centre, Cancer Council Victoria, 3004, Melbourne, Australia
    671 rdf:type schema:Organization
    672 https://www.grid.ac/institutes/grid.34477.33 schema:alternateName University of Washington
    673 schema:name Department of Biostatistics, University of Washington, 98195, Seattle, WA, USA
    674 rdf:type schema:Organization
    675 https://www.grid.ac/institutes/grid.410552.7 schema:alternateName Turku University Hospital
    676 schema:name Tyks Microbiology and Genetics, Department of Medical Genetics, Turku University Hospital, 20520, Turku, Finland
    677 rdf:type schema:Organization
    678 https://www.grid.ac/institutes/grid.410711.2 schema:alternateName University of North Carolina System
    679 schema:name Department of Biostatistics, University of North Carolina, 27599, Chapel Hill, NC, USA
    680 Department of Genetics, University of North Carolina, 27599, Chapel Hill, NC, USA
    681 rdf:type schema:Organization
    682 https://www.grid.ac/institutes/grid.410712.1 schema:alternateName University Hospital Ulm
    683 schema:name Department of Urology, University Hospital Ulm, 53179, Ulm, Germany
    684 rdf:type schema:Organization
    685 https://www.grid.ac/institutes/grid.412330.7 schema:alternateName Tampere University Hospital
    686 schema:name Department of Urology, University of Tampere and Tampere University Hospital, 33520, Tampere, Finland
    687 rdf:type schema:Organization
    688 https://www.grid.ac/institutes/grid.412722.0 schema:alternateName University of Utah Health Care
    689 schema:name Department of Surgery, University of Utah School of Medicine, 84132, Salt Lake City, UT, USA
    690 Department of Urology, University of Utah School of Medicine, 84132, Salt Lake City, UT, USA
    691 Huntsman Cancer Institute, University of Utah, 84112, Salt Lake City, UT, USA
    692 rdf:type schema:Organization
    693 https://www.grid.ac/institutes/grid.413886.0 schema:alternateName George E. Wahlen Department of VA Medical Center
    694 schema:name Department of Internal Medicine, University of Utah School of Medicine, 84108, Salt Lake City, UT, USA
    695 George E. Wahlen Department of Veterans Affairs Medical Center, 84148, Salt Lake City, UT, USA
    696 rdf:type schema:Organization
    697 https://www.grid.ac/institutes/grid.6582.9 schema:alternateName University of Ulm
    698 schema:name Institute for Human Genetics, University of Ulm, 89081, Ulm, Germany
    699 rdf:type schema:Organization
    700 https://www.grid.ac/institutes/grid.66875.3a schema:alternateName Mayo Clinic
    701 schema:name Department of Health Sciences Research, Mayo Clinic, 55905, Rochester, MN, USA
    702 Department of Lab Medicine and Pathology, Mayo Clinic, 55905, Rochester, MN, USA
    703 rdf:type schema:Organization
     




    Preview window. Press ESC to close (or click here)


    ...