Stomach cancer mortality among workers exposed to asbestos: a meta-analysis View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2015-07

AUTHORS

Wen-jia Peng, Xian-jie Jia, Bing-gan Wei, Lin-sheng Yang, Ying Yu, Lei Zhang

ABSTRACT

BACKGROUND: The relationship between asbestos and stomach cancer is not well understood because of small number of cases. This study aimed to determine the incidence and mortality of stomach cancer among workers exposed to asbestos based on a systematic review and meta-analysis approach. METHODS: Relevant English electronic databases were systematically searched for published studies characterizing the risk of developing stomach cancer as a result of asbestos exposure. Standardized mortality rate (SMR) for stomach cancer with its 95% confidence interval (CI) was pooled using a fixed-/random-effect model in STATA. RESULTS: A total of 32 independent studies were included for the analysis. The overall SMR for stomach cancer was 1.19 (95% CI 1.06-1.34), with a moderate degree of heterogeneity across the studies (I(2) = 37.6%, P = 0.011). Being male, exposure to crocidolite, miners, studies conducted in Europe and Oceania, and long study follow-up (≥ 25 years) all contribute to significantly higher SMR. Significant publication bias was observed. CONCLUSION: Elevated risk of stomach cancer mortality was evidenced among workers exposed to crocidolite, especially male miners. More... »

PAGES

1141-1149

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00432-014-1791-3

DOI

http://dx.doi.org/10.1007/s00432-014-1791-3

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1012832543

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/25115694


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