Src/ERK but not phospholipase D is involved in keratinocyte growth factor-stimulated secretion of matrix metalloprotease-9 and urokinase-type plasminogen activator in ... View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2002-11

AUTHORS

Eun-Young Shin, Eun-Kyung Ma, Chi-Kyung Kim, Sahng-June Kwak, Eung-Gook Kim

ABSTRACT

PURPOSE: We investigated the signaling pathway for keratinocyte growth factor (KGF)-induced invasion using human stomach cancer cell line, SNU-16. METHODS: Alterations in the activities of Src, extracellular signal-regulated kinase (ERK), and phospholipase D (PLD) were measured using [gamma-(32)P] ATP for autophosphorylation of Src, phospho-specific ERK antibody, and [9,10-(3)H] myristic acid, respectively, while herbimycin A, PD98059 and butan-1-ol were used to inhibit their activities. Matrix metalloproteases (MMPs) and urokinase-type plasminogen activator (uPA) were quantified with zymography and Matrigel-coated Transwell was employed to estimate the invasiveness of SNU-16 cells. RESULTS: Src, ERK, and PLD were activated in response to KGF treatment, and inhibition of these enzymes - by their specific inhibitors - decreased KGF-induced invasion in a dose-dependent manner. However, only inhibition of Src and ERK could block KGF-stimulated secretion of uPA and MMP-9. CONCLUSION: Src, ERK, and PLD are suggested as mediators of KGF-induced invasion in SNU-16. uPA and MMP-9 are considered as downstream targets of Src and ERK whereas PLD is thought to utilize different pathways. More... »

PAGES

596-602

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00432-002-0388-4

DOI

http://dx.doi.org/10.1007/s00432-002-0388-4

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1052599593

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/12458339


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0601", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biochemistry and Cell Biology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Calcium-Calmodulin-Dependent Protein Kinases", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Collagen", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Drug Combinations", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Enzyme Inhibitors", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Fibroblast Growth Factor 7", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Fibroblast Growth Factors", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Flavonoids", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Laminin", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Matrix Metalloproteinase 9", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mitogen-Activated Protein Kinases", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Neoplasm Invasiveness", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Phospholipase D", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Phosphorylation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Proteoglycans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Proto-Oncogene Proteins pp60(c-src)", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Receptor, Fibroblast Growth Factor, Type 2", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Receptors, Fibroblast Growth Factor", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Signal Transduction", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Stomach Neoplasms", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Tumor Cells, Cultured", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Urokinase-Type Plasminogen Activator", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Chungbuk National University", 
          "id": "https://www.grid.ac/institutes/grid.254229.a", 
          "name": [
            "Department of Biochemistry, College of Medicine, Medical Research Institute and Biotechnology Research Institute, Chungbuk National University, San 48, Gaesin-dong, Heungduk-ku, Cheongju, 361\u2013763, Korea"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Shin", 
        "givenName": "Eun-Young", 
        "id": "sg:person.010546405112.63", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010546405112.63"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Chungbuk National University", 
          "id": "https://www.grid.ac/institutes/grid.254229.a", 
          "name": [
            "Department of Microbiology and Biotechnology, and Biotechnology Research Institute, Chungbuk National University, Cheongju, 361-763, Korea"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ma", 
        "givenName": "Eun-Kyung", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Chungbuk National University", 
          "id": "https://www.grid.ac/institutes/grid.254229.a", 
          "name": [
            "Department of Microbiology and Biotechnology, and Biotechnology Research Institute, Chungbuk National University, Cheongju, 361-763, Korea"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kim", 
        "givenName": "Chi-Kyung", 
        "id": "sg:person.0746541674.54", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0746541674.54"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Dankook University", 
          "id": "https://www.grid.ac/institutes/grid.411982.7", 
          "name": [
            "Department of Biochemistry, College of Medicine, Dankook University, Cheonan, 330\u2013714, Korea"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kwak", 
        "givenName": "Sahng-June", 
        "id": "sg:person.0771422613.08", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0771422613.08"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Chungbuk National University", 
          "id": "https://www.grid.ac/institutes/grid.254229.a", 
          "name": [
            "Department of Biochemistry, College of Medicine, Medical Research Institute and Biotechnology Research Institute, Chungbuk National University, San 48, Gaesin-dong, Heungduk-ku, Cheongju, 361\u2013763, Korea"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kim", 
        "givenName": "Eung-Gook", 
        "id": "sg:person.01266456772.16", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01266456772.16"
        ], 
        "type": "Person"
      }
    ], 
    "datePublished": "2002-11", 
    "datePublishedReg": "2002-11-01", 
    "description": "PURPOSE: We investigated the signaling pathway for keratinocyte growth factor (KGF)-induced invasion using human stomach cancer cell line, SNU-16.\nMETHODS: Alterations in the activities of Src, extracellular signal-regulated kinase (ERK), and phospholipase D (PLD) were measured using [gamma-(32)P] ATP for autophosphorylation of Src, phospho-specific ERK antibody, and [9,10-(3)H] myristic acid, respectively, while herbimycin A, PD98059 and butan-1-ol were used to inhibit their activities. Matrix metalloproteases (MMPs) and urokinase-type plasminogen activator (uPA) were quantified with zymography and Matrigel-coated Transwell was employed to estimate the invasiveness of SNU-16 cells.\nRESULTS: Src, ERK, and PLD were activated in response to KGF treatment, and inhibition of these enzymes - by their specific inhibitors - decreased KGF-induced invasion in a dose-dependent manner. However, only inhibition of Src and ERK could block KGF-stimulated secretion of uPA and MMP-9.\nCONCLUSION: Src, ERK, and PLD are suggested as mediators of KGF-induced invasion in SNU-16. uPA and MMP-9 are considered as downstream targets of Src and ERK whereas PLD is thought to utilize different pathways.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s00432-002-0388-4", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1313647", 
        "issn": [
          "0171-5216", 
          "1432-1335"
        ], 
        "name": "Journal of Cancer Research and Clinical Oncology", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "11", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "128"
      }
    ], 
    "name": "Src/ERK but not phospholipase D is involved in keratinocyte growth factor-stimulated secretion of matrix metalloprotease-9 and urokinase-type plasminogen activator in SNU-16 human stomach cancer cell", 
    "pagination": "596-602", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "fa8c812ab77ee3f27441f77b895680f46beae5d0fbb26d1f975a458ecec4a1b7"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "12458339"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "7902060"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s00432-002-0388-4"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1052599593"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s00432-002-0388-4", 
      "https://app.dimensions.ai/details/publication/pub.1052599593"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T19:04", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8678_00000492.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1007/s00432-002-0388-4"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00432-002-0388-4'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00432-002-0388-4'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00432-002-0388-4'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00432-002-0388-4'


 

This table displays all metadata directly associated to this object as RDF triples.

188 TRIPLES      20 PREDICATES      51 URIs      43 LITERALS      31 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s00432-002-0388-4 schema:about N05ef4bb6959243fc8791ff3478d72ab8
2 N1aeed69eba6f42faa785f2071bad700a
3 N2a1561ee2b2c4d50904576d23ce29b12
4 N2bb7956e144742dc9484096c2412c2b2
5 N4149f12271fa4086ab4e3ba679d93f47
6 N4690a3ccbd8b41cf8613162f01427139
7 N52b01f25dd6040f780a4ee6be14050cb
8 N55333c32ee604482a6c0459556a5db84
9 N69e4f8a69c5c49ceb357a9c1ff3c4897
10 N728432ff290647dab800d6e0277f87a8
11 N89284c947bd44e65ad946062a3386a5c
12 N9f2554729ef5457aaa0863c374a2fcda
13 Na136e2ef212c4371b28dccc564299c93
14 Nac1bc5ca3748433ba7cc5fb14cec2da8
15 Naf343f77b96242ebbb077c3d458f1855
16 Nb3028edf9ad1489189b241efeb62de8a
17 Nbd253f45d4c64677bfa37f281174244b
18 Nbeb6bc7f6bbd49f7938ea8639f01bbbb
19 Ncb55666ba27348a1b4d0be3cc9a4ac44
20 Ne327534bd50943ceb6660a330c86863e
21 Ne41b872004af4f9784afb1f0411b0d9a
22 Neb6957ff06224adfb2f3858edba68ec2
23 anzsrc-for:06
24 anzsrc-for:0601
25 schema:author N6abb74e173d34ed7bc634e373963ee09
26 schema:datePublished 2002-11
27 schema:datePublishedReg 2002-11-01
28 schema:description PURPOSE: We investigated the signaling pathway for keratinocyte growth factor (KGF)-induced invasion using human stomach cancer cell line, SNU-16. METHODS: Alterations in the activities of Src, extracellular signal-regulated kinase (ERK), and phospholipase D (PLD) were measured using [gamma-(32)P] ATP for autophosphorylation of Src, phospho-specific ERK antibody, and [9,10-(3)H] myristic acid, respectively, while herbimycin A, PD98059 and butan-1-ol were used to inhibit their activities. Matrix metalloproteases (MMPs) and urokinase-type plasminogen activator (uPA) were quantified with zymography and Matrigel-coated Transwell was employed to estimate the invasiveness of SNU-16 cells. RESULTS: Src, ERK, and PLD were activated in response to KGF treatment, and inhibition of these enzymes - by their specific inhibitors - decreased KGF-induced invasion in a dose-dependent manner. However, only inhibition of Src and ERK could block KGF-stimulated secretion of uPA and MMP-9. CONCLUSION: Src, ERK, and PLD are suggested as mediators of KGF-induced invasion in SNU-16. uPA and MMP-9 are considered as downstream targets of Src and ERK whereas PLD is thought to utilize different pathways.
29 schema:genre research_article
30 schema:inLanguage en
31 schema:isAccessibleForFree false
32 schema:isPartOf N3a3ddd4d17f54b38a1a5c3e05a9e1ae3
33 N4ea6be6c437a459fabb4458df8392710
34 sg:journal.1313647
35 schema:name Src/ERK but not phospholipase D is involved in keratinocyte growth factor-stimulated secretion of matrix metalloprotease-9 and urokinase-type plasminogen activator in SNU-16 human stomach cancer cell
36 schema:pagination 596-602
37 schema:productId N55d2e20b211b4690b12434b0eff644b8
38 N707db77ffe4548ad8d79d8680980b908
39 N8d92d5b180cd405cacaef3662988302c
40 Nc07962599713445ea8aee351fd1aeec5
41 Ned502bcb7db94952ab2bc19df80f1b35
42 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052599593
43 https://doi.org/10.1007/s00432-002-0388-4
44 schema:sdDatePublished 2019-04-10T19:04
45 schema:sdLicense https://scigraph.springernature.com/explorer/license/
46 schema:sdPublisher N2ee520105ca24e6390d150f27f42c6aa
47 schema:url http://link.springer.com/10.1007/s00432-002-0388-4
48 sgo:license sg:explorer/license/
49 sgo:sdDataset articles
50 rdf:type schema:ScholarlyArticle
51 N05ef4bb6959243fc8791ff3478d72ab8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
52 schema:name Matrix Metalloproteinase 9
53 rdf:type schema:DefinedTerm
54 N06f0b40f2ae14596807009635668e556 rdf:first sg:person.01266456772.16
55 rdf:rest rdf:nil
56 N1aeed69eba6f42faa785f2071bad700a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
57 schema:name Phosphorylation
58 rdf:type schema:DefinedTerm
59 N2a1561ee2b2c4d50904576d23ce29b12 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
60 schema:name Signal Transduction
61 rdf:type schema:DefinedTerm
62 N2bb7956e144742dc9484096c2412c2b2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
63 schema:name Stomach Neoplasms
64 rdf:type schema:DefinedTerm
65 N2ee520105ca24e6390d150f27f42c6aa schema:name Springer Nature - SN SciGraph project
66 rdf:type schema:Organization
67 N3a3ddd4d17f54b38a1a5c3e05a9e1ae3 schema:volumeNumber 128
68 rdf:type schema:PublicationVolume
69 N4149f12271fa4086ab4e3ba679d93f47 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
70 schema:name Enzyme Inhibitors
71 rdf:type schema:DefinedTerm
72 N4690a3ccbd8b41cf8613162f01427139 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
73 schema:name Drug Combinations
74 rdf:type schema:DefinedTerm
75 N4ea6be6c437a459fabb4458df8392710 schema:issueNumber 11
76 rdf:type schema:PublicationIssue
77 N52b01f25dd6040f780a4ee6be14050cb schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
78 schema:name Laminin
79 rdf:type schema:DefinedTerm
80 N55333c32ee604482a6c0459556a5db84 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
81 schema:name Receptor, Fibroblast Growth Factor, Type 2
82 rdf:type schema:DefinedTerm
83 N55d2e20b211b4690b12434b0eff644b8 schema:name doi
84 schema:value 10.1007/s00432-002-0388-4
85 rdf:type schema:PropertyValue
86 N61c8e4e056d44f698eb1f0eb4d73d142 rdf:first Na9966e1df02c498899628e1c103436ac
87 rdf:rest Ncea68d02b4104cb68c230b20a3eb32ea
88 N69e4f8a69c5c49ceb357a9c1ff3c4897 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
89 schema:name Urokinase-Type Plasminogen Activator
90 rdf:type schema:DefinedTerm
91 N6abb74e173d34ed7bc634e373963ee09 rdf:first sg:person.010546405112.63
92 rdf:rest N61c8e4e056d44f698eb1f0eb4d73d142
93 N707db77ffe4548ad8d79d8680980b908 schema:name pubmed_id
94 schema:value 12458339
95 rdf:type schema:PropertyValue
96 N728432ff290647dab800d6e0277f87a8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
97 schema:name Phospholipase D
98 rdf:type schema:DefinedTerm
99 N7d9463072b7b4a9cb774a50d5fa096cf rdf:first sg:person.0771422613.08
100 rdf:rest N06f0b40f2ae14596807009635668e556
101 N89284c947bd44e65ad946062a3386a5c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
102 schema:name Proto-Oncogene Proteins pp60(c-src)
103 rdf:type schema:DefinedTerm
104 N8d92d5b180cd405cacaef3662988302c schema:name dimensions_id
105 schema:value pub.1052599593
106 rdf:type schema:PropertyValue
107 N9f2554729ef5457aaa0863c374a2fcda schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
108 schema:name Fibroblast Growth Factors
109 rdf:type schema:DefinedTerm
110 Na136e2ef212c4371b28dccc564299c93 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
111 schema:name Neoplasm Invasiveness
112 rdf:type schema:DefinedTerm
113 Na9966e1df02c498899628e1c103436ac schema:affiliation https://www.grid.ac/institutes/grid.254229.a
114 schema:familyName Ma
115 schema:givenName Eun-Kyung
116 rdf:type schema:Person
117 Nac1bc5ca3748433ba7cc5fb14cec2da8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
118 schema:name Humans
119 rdf:type schema:DefinedTerm
120 Naf343f77b96242ebbb077c3d458f1855 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
121 schema:name Fibroblast Growth Factor 7
122 rdf:type schema:DefinedTerm
123 Nb3028edf9ad1489189b241efeb62de8a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
124 schema:name Mitogen-Activated Protein Kinases
125 rdf:type schema:DefinedTerm
126 Nbd253f45d4c64677bfa37f281174244b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
127 schema:name Tumor Cells, Cultured
128 rdf:type schema:DefinedTerm
129 Nbeb6bc7f6bbd49f7938ea8639f01bbbb schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
130 schema:name Calcium-Calmodulin-Dependent Protein Kinases
131 rdf:type schema:DefinedTerm
132 Nc07962599713445ea8aee351fd1aeec5 schema:name readcube_id
133 schema:value fa8c812ab77ee3f27441f77b895680f46beae5d0fbb26d1f975a458ecec4a1b7
134 rdf:type schema:PropertyValue
135 Ncb55666ba27348a1b4d0be3cc9a4ac44 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
136 schema:name Collagen
137 rdf:type schema:DefinedTerm
138 Ncea68d02b4104cb68c230b20a3eb32ea rdf:first sg:person.0746541674.54
139 rdf:rest N7d9463072b7b4a9cb774a50d5fa096cf
140 Ne327534bd50943ceb6660a330c86863e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
141 schema:name Proteoglycans
142 rdf:type schema:DefinedTerm
143 Ne41b872004af4f9784afb1f0411b0d9a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
144 schema:name Receptors, Fibroblast Growth Factor
145 rdf:type schema:DefinedTerm
146 Neb6957ff06224adfb2f3858edba68ec2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
147 schema:name Flavonoids
148 rdf:type schema:DefinedTerm
149 Ned502bcb7db94952ab2bc19df80f1b35 schema:name nlm_unique_id
150 schema:value 7902060
151 rdf:type schema:PropertyValue
152 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
153 schema:name Biological Sciences
154 rdf:type schema:DefinedTerm
155 anzsrc-for:0601 schema:inDefinedTermSet anzsrc-for:
156 schema:name Biochemistry and Cell Biology
157 rdf:type schema:DefinedTerm
158 sg:journal.1313647 schema:issn 0171-5216
159 1432-1335
160 schema:name Journal of Cancer Research and Clinical Oncology
161 rdf:type schema:Periodical
162 sg:person.010546405112.63 schema:affiliation https://www.grid.ac/institutes/grid.254229.a
163 schema:familyName Shin
164 schema:givenName Eun-Young
165 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010546405112.63
166 rdf:type schema:Person
167 sg:person.01266456772.16 schema:affiliation https://www.grid.ac/institutes/grid.254229.a
168 schema:familyName Kim
169 schema:givenName Eung-Gook
170 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01266456772.16
171 rdf:type schema:Person
172 sg:person.0746541674.54 schema:affiliation https://www.grid.ac/institutes/grid.254229.a
173 schema:familyName Kim
174 schema:givenName Chi-Kyung
175 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0746541674.54
176 rdf:type schema:Person
177 sg:person.0771422613.08 schema:affiliation https://www.grid.ac/institutes/grid.411982.7
178 schema:familyName Kwak
179 schema:givenName Sahng-June
180 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0771422613.08
181 rdf:type schema:Person
182 https://www.grid.ac/institutes/grid.254229.a schema:alternateName Chungbuk National University
183 schema:name Department of Biochemistry, College of Medicine, Medical Research Institute and Biotechnology Research Institute, Chungbuk National University, San 48, Gaesin-dong, Heungduk-ku, Cheongju, 361–763, Korea
184 Department of Microbiology and Biotechnology, and Biotechnology Research Institute, Chungbuk National University, Cheongju, 361-763, Korea
185 rdf:type schema:Organization
186 https://www.grid.ac/institutes/grid.411982.7 schema:alternateName Dankook University
187 schema:name Department of Biochemistry, College of Medicine, Dankook University, Cheonan, 330–714, Korea
188 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...