Neurological outcome in adult patients with early-treated phenylketonuria View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1998-09

AUTHORS

J. Pietz, R. Dunckelmann, A. Rupp, D. Rating, H.-M. Meinck, H. Schmidt, H. J. Bremer

ABSTRACT

Due to the observation of severe neurological symptoms in single patients as well as brain imaging, neuropsychological and neurophysiological abnormalities, the long-term prognosis of treated phenylketonuria is still under discussion. We investigated the neurological outcome of 57 (24 male, 33 female) patients with phenylketonuria (diet onset < 3 months) at a mean age of 23.6 (17-33) years in comparison to control subjects. Methods used were a clinical-neurological examination, tests for fine motor abilities, IQ test (WAIS-R), a neuropsychological attention task and MRI (30 patients only). Tremor was increased in the patients (28%) compared to controls (15%). Fine motor abilities were significantly reduced in three areas: hand-wrist steadiness, finger-hand dexterity and hand-wrist speed. Tremor as well as reduced fine motor skills were not associated with treatment-related variables, e.g. diet onset, strictness of biochemical control or amount of MRI white matter change. IQ was lower in patients (mean 97.6) compared to matched control subjects (mean 105.5). IQ at 12 years was correlated with biochemical control from birth up to the age of 12 and remained stable up to adult age, independent of biochemical control after 12 years of age. In contrast to the other outcome parameters, the performance in a neuropsychological attention task was influenced by the concurrent plasma phenylalanine concentration. Specific late-onset neurological impairment was not identified in this sample of early-treated adults with phenylketonuria. CONCLUSION: Careful neurological investigation revealed subtle symptoms of brain damage even after early-initiated treatment in adult patients with phenylketonuria. At present it cannot be excluded that further neurological deterioration could emerge later in life. Thus, patients with phenylketonuria - either on or off diet - should be monitored throughout life. More... »

PAGES

824-830

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s004310050945

DOI

http://dx.doi.org/10.1007/s004310050945

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1026447070

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/9809823


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1109", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Neurosciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adolescent", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adult", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Attention", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cross-Sectional Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Motor Skills", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Nervous System Diseases", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Neurobehavioral Manifestations", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Neuropsychological Tests", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Phenylketonurias", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Heidelberg University", 
          "id": "https://www.grid.ac/institutes/grid.7700.0", 
          "name": [
            "Department of Paediatric Neurology, University of Heidelberg, Im Neuenheimer Feld 150, D-69120 Heidelberg, Germany Tel.: +49-6221-562311  Fax: +49-6221-565744, DE"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Pietz", 
        "givenName": "J.", 
        "id": "sg:person.0643257562.30", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0643257562.30"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Heidelberg University", 
          "id": "https://www.grid.ac/institutes/grid.7700.0", 
          "name": [
            "Department of Paediatric Neurology, University of Heidelberg, Im Neuenheimer Feld 150, D-69120 Heidelberg, Germany Tel.: +49-6221-562311  Fax: +49-6221-565744, DE"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Dunckelmann", 
        "givenName": "R.", 
        "id": "sg:person.0753751540.72", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0753751540.72"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Heidelberg University", 
          "id": "https://www.grid.ac/institutes/grid.7700.0", 
          "name": [
            "Department of Paediatric Neurology, University of Heidelberg, Im Neuenheimer Feld 150, D-69120 Heidelberg, Germany Tel.: +49-6221-562311  Fax: +49-6221-565744, DE"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Rupp", 
        "givenName": "A.", 
        "id": "sg:person.01011361550.80", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01011361550.80"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Heidelberg University", 
          "id": "https://www.grid.ac/institutes/grid.7700.0", 
          "name": [
            "Department of Paediatric Neurology, University of Heidelberg, Im Neuenheimer Feld 150, D-69120 Heidelberg, Germany Tel.: +49-6221-562311  Fax: +49-6221-565744, DE"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Rating", 
        "givenName": "D.", 
        "id": "sg:person.01233310642.63", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01233310642.63"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Heidelberg University", 
          "id": "https://www.grid.ac/institutes/grid.7700.0", 
          "name": [
            "Department of Neurology, University of Heidelberg, Im Neuenheimer Feld 150, D-69120 Heidelberg, Germany, DE"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Meinck", 
        "givenName": "H.-M.", 
        "id": "sg:person.0642523006.25", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0642523006.25"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Heidelberg University", 
          "id": "https://www.grid.ac/institutes/grid.7700.0", 
          "name": [
            "Department of General Paediatric, University of Heidelberg, Im Neuenheimer Feld 150, D-69120 Heidelberg, Germany, DE"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Schmidt", 
        "givenName": "H.", 
        "id": "sg:person.01344555646.31", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01344555646.31"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Heidelberg University", 
          "id": "https://www.grid.ac/institutes/grid.7700.0", 
          "name": [
            "Department of General Paediatric, University of Heidelberg, Im Neuenheimer Feld 150, D-69120 Heidelberg, Germany, DE"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Bremer", 
        "givenName": "H. J.", 
        "id": "sg:person.0105362105.51", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0105362105.51"
        ], 
        "type": "Person"
      }
    ], 
    "datePublished": "1998-09", 
    "datePublishedReg": "1998-09-01", 
    "description": "Due to the observation of severe neurological symptoms in single patients as well as brain imaging, neuropsychological and neurophysiological abnormalities, the long-term prognosis of treated phenylketonuria is still under discussion. We investigated the neurological outcome of 57 (24 male, 33 female) patients with phenylketonuria (diet onset < 3 months) at a mean age of 23.6 (17-33) years in comparison to control subjects. Methods used were a clinical-neurological examination, tests for fine motor abilities, IQ test (WAIS-R), a neuropsychological attention task and MRI (30 patients only). Tremor was increased in the patients (28%) compared to controls (15%). Fine motor abilities were significantly reduced in three areas: hand-wrist steadiness, finger-hand dexterity and hand-wrist speed. Tremor as well as reduced fine motor skills were not associated with treatment-related variables, e.g. diet onset, strictness of biochemical control or amount of MRI white matter change. IQ was lower in patients (mean 97.6) compared to matched control subjects (mean 105.5). IQ at 12 years was correlated with biochemical control from birth up to the age of 12 and remained stable up to adult age, independent of biochemical control after 12 years of age. In contrast to the other outcome parameters, the performance in a neuropsychological attention task was influenced by the concurrent plasma phenylalanine concentration. Specific late-onset neurological impairment was not identified in this sample of early-treated adults with phenylketonuria.\nCONCLUSION: Careful neurological investigation revealed subtle symptoms of brain damage even after early-initiated treatment in adult patients with phenylketonuria. At present it cannot be excluded that further neurological deterioration could emerge later in life. Thus, patients with phenylketonuria - either on or off diet - should be monitored throughout life.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s004310050945", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1017354", 
        "issn": [
          "0340-6199", 
          "1432-1076"
        ], 
        "name": "European Journal of Pediatrics", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "10", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "157"
      }
    ], 
    "name": "Neurological outcome in adult patients with early-treated phenylketonuria", 
    "pagination": "824-830", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "7dfe03ab468338368b343c40a5031573557ce9389c30b54a595ce77beffaab43"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "9809823"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "7603873"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s004310050945"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1026447070"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s004310050945", 
      "https://app.dimensions.ai/details/publication/pub.1026447070"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T15:46", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8664_00000488.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1007/s004310050945"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s004310050945'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s004310050945'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s004310050945'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s004310050945'


 

This table displays all metadata directly associated to this object as RDF triples.

161 TRIPLES      20 PREDICATES      41 URIs      33 LITERALS      21 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s004310050945 schema:about N07aa0c6b6618401eba774a75a3f7cfa0
2 N37e585b5f4b64e0f93c6ab3b4e1403d9
3 N38f87d517d4d4027a7c91cf2b8af5f7e
4 N437cc6319e1743bc85dea3e5d11167e4
5 N61a79a33f33a4da698f32df2c49231b9
6 N68458834f2cc483995cb9932784853cb
7 N81c9926f917f4f55898539d7d04481df
8 N8a2c534cf3cb46fd89eb458081468e97
9 Na3a427c6c291497ebe7ed39bdc471838
10 Naad678ef9dd3417aabb7bd4279cc5b5d
11 Ned55aba78bed4316b8febb23be9005e9
12 Nf1320d45e38c4c3f987ba605ede1871a
13 anzsrc-for:11
14 anzsrc-for:1109
15 schema:author Nd187106c14b44c9e9c8a8ef13cf39121
16 schema:datePublished 1998-09
17 schema:datePublishedReg 1998-09-01
18 schema:description Due to the observation of severe neurological symptoms in single patients as well as brain imaging, neuropsychological and neurophysiological abnormalities, the long-term prognosis of treated phenylketonuria is still under discussion. We investigated the neurological outcome of 57 (24 male, 33 female) patients with phenylketonuria (diet onset < 3 months) at a mean age of 23.6 (17-33) years in comparison to control subjects. Methods used were a clinical-neurological examination, tests for fine motor abilities, IQ test (WAIS-R), a neuropsychological attention task and MRI (30 patients only). Tremor was increased in the patients (28%) compared to controls (15%). Fine motor abilities were significantly reduced in three areas: hand-wrist steadiness, finger-hand dexterity and hand-wrist speed. Tremor as well as reduced fine motor skills were not associated with treatment-related variables, e.g. diet onset, strictness of biochemical control or amount of MRI white matter change. IQ was lower in patients (mean 97.6) compared to matched control subjects (mean 105.5). IQ at 12 years was correlated with biochemical control from birth up to the age of 12 and remained stable up to adult age, independent of biochemical control after 12 years of age. In contrast to the other outcome parameters, the performance in a neuropsychological attention task was influenced by the concurrent plasma phenylalanine concentration. Specific late-onset neurological impairment was not identified in this sample of early-treated adults with phenylketonuria. CONCLUSION: Careful neurological investigation revealed subtle symptoms of brain damage even after early-initiated treatment in adult patients with phenylketonuria. At present it cannot be excluded that further neurological deterioration could emerge later in life. Thus, patients with phenylketonuria - either on or off diet - should be monitored throughout life.
19 schema:genre research_article
20 schema:inLanguage en
21 schema:isAccessibleForFree false
22 schema:isPartOf N024d97f11fca43a3b448270a679f48ce
23 N909420808bfe42b1974bd8e17f3511f9
24 sg:journal.1017354
25 schema:name Neurological outcome in adult patients with early-treated phenylketonuria
26 schema:pagination 824-830
27 schema:productId N24165ecc15a6440fb31c3e50b4ba4ac7
28 N5ac2f563d4b6474789a09be2c8316119
29 N636d3c35e5cf4a08807143e446d0cc4b
30 N6a3fb94104524d35a6a3a2bd25f17e3c
31 N6f5418fbe81348f6b296089ec1d68c4e
32 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026447070
33 https://doi.org/10.1007/s004310050945
34 schema:sdDatePublished 2019-04-10T15:46
35 schema:sdLicense https://scigraph.springernature.com/explorer/license/
36 schema:sdPublisher N68b6a4a514d94463ad1fa2e4be9188d8
37 schema:url http://link.springer.com/10.1007/s004310050945
38 sgo:license sg:explorer/license/
39 sgo:sdDataset articles
40 rdf:type schema:ScholarlyArticle
41 N024d97f11fca43a3b448270a679f48ce schema:volumeNumber 157
42 rdf:type schema:PublicationVolume
43 N07aa0c6b6618401eba774a75a3f7cfa0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
44 schema:name Nervous System Diseases
45 rdf:type schema:DefinedTerm
46 N24165ecc15a6440fb31c3e50b4ba4ac7 schema:name dimensions_id
47 schema:value pub.1026447070
48 rdf:type schema:PropertyValue
49 N37e585b5f4b64e0f93c6ab3b4e1403d9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
50 schema:name Male
51 rdf:type schema:DefinedTerm
52 N38f87d517d4d4027a7c91cf2b8af5f7e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
53 schema:name Adolescent
54 rdf:type schema:DefinedTerm
55 N437cc6319e1743bc85dea3e5d11167e4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
56 schema:name Female
57 rdf:type schema:DefinedTerm
58 N45728d031abe4856ab1193c24fc41c0f rdf:first sg:person.01233310642.63
59 rdf:rest N59f375accb4e4cc4b2cb569131125da4
60 N59f375accb4e4cc4b2cb569131125da4 rdf:first sg:person.0642523006.25
61 rdf:rest Nee2bd84aa4804671a9f6ceb2d4e4e670
62 N5ac2f563d4b6474789a09be2c8316119 schema:name doi
63 schema:value 10.1007/s004310050945
64 rdf:type schema:PropertyValue
65 N5c3e130527184f3c9b4ca315ab221f0f rdf:first sg:person.01011361550.80
66 rdf:rest N45728d031abe4856ab1193c24fc41c0f
67 N61a79a33f33a4da698f32df2c49231b9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
68 schema:name Adult
69 rdf:type schema:DefinedTerm
70 N636d3c35e5cf4a08807143e446d0cc4b schema:name pubmed_id
71 schema:value 9809823
72 rdf:type schema:PropertyValue
73 N68458834f2cc483995cb9932784853cb schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
74 schema:name Motor Skills
75 rdf:type schema:DefinedTerm
76 N68b6a4a514d94463ad1fa2e4be9188d8 schema:name Springer Nature - SN SciGraph project
77 rdf:type schema:Organization
78 N6a3fb94104524d35a6a3a2bd25f17e3c schema:name readcube_id
79 schema:value 7dfe03ab468338368b343c40a5031573557ce9389c30b54a595ce77beffaab43
80 rdf:type schema:PropertyValue
81 N6f5418fbe81348f6b296089ec1d68c4e schema:name nlm_unique_id
82 schema:value 7603873
83 rdf:type schema:PropertyValue
84 N81c9926f917f4f55898539d7d04481df schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
85 schema:name Phenylketonurias
86 rdf:type schema:DefinedTerm
87 N8a2c534cf3cb46fd89eb458081468e97 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
88 schema:name Attention
89 rdf:type schema:DefinedTerm
90 N909420808bfe42b1974bd8e17f3511f9 schema:issueNumber 10
91 rdf:type schema:PublicationIssue
92 Na3a427c6c291497ebe7ed39bdc471838 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
93 schema:name Humans
94 rdf:type schema:DefinedTerm
95 Naad678ef9dd3417aabb7bd4279cc5b5d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
96 schema:name Neuropsychological Tests
97 rdf:type schema:DefinedTerm
98 Nb482b6480d5a43b8956422673e2cab31 rdf:first sg:person.0105362105.51
99 rdf:rest rdf:nil
100 Nbb83d1675c694f28ba74d17995e7c53e rdf:first sg:person.0753751540.72
101 rdf:rest N5c3e130527184f3c9b4ca315ab221f0f
102 Nd187106c14b44c9e9c8a8ef13cf39121 rdf:first sg:person.0643257562.30
103 rdf:rest Nbb83d1675c694f28ba74d17995e7c53e
104 Ned55aba78bed4316b8febb23be9005e9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
105 schema:name Cross-Sectional Studies
106 rdf:type schema:DefinedTerm
107 Nee2bd84aa4804671a9f6ceb2d4e4e670 rdf:first sg:person.01344555646.31
108 rdf:rest Nb482b6480d5a43b8956422673e2cab31
109 Nf1320d45e38c4c3f987ba605ede1871a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
110 schema:name Neurobehavioral Manifestations
111 rdf:type schema:DefinedTerm
112 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
113 schema:name Medical and Health Sciences
114 rdf:type schema:DefinedTerm
115 anzsrc-for:1109 schema:inDefinedTermSet anzsrc-for:
116 schema:name Neurosciences
117 rdf:type schema:DefinedTerm
118 sg:journal.1017354 schema:issn 0340-6199
119 1432-1076
120 schema:name European Journal of Pediatrics
121 rdf:type schema:Periodical
122 sg:person.01011361550.80 schema:affiliation https://www.grid.ac/institutes/grid.7700.0
123 schema:familyName Rupp
124 schema:givenName A.
125 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01011361550.80
126 rdf:type schema:Person
127 sg:person.0105362105.51 schema:affiliation https://www.grid.ac/institutes/grid.7700.0
128 schema:familyName Bremer
129 schema:givenName H. J.
130 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0105362105.51
131 rdf:type schema:Person
132 sg:person.01233310642.63 schema:affiliation https://www.grid.ac/institutes/grid.7700.0
133 schema:familyName Rating
134 schema:givenName D.
135 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01233310642.63
136 rdf:type schema:Person
137 sg:person.01344555646.31 schema:affiliation https://www.grid.ac/institutes/grid.7700.0
138 schema:familyName Schmidt
139 schema:givenName H.
140 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01344555646.31
141 rdf:type schema:Person
142 sg:person.0642523006.25 schema:affiliation https://www.grid.ac/institutes/grid.7700.0
143 schema:familyName Meinck
144 schema:givenName H.-M.
145 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0642523006.25
146 rdf:type schema:Person
147 sg:person.0643257562.30 schema:affiliation https://www.grid.ac/institutes/grid.7700.0
148 schema:familyName Pietz
149 schema:givenName J.
150 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0643257562.30
151 rdf:type schema:Person
152 sg:person.0753751540.72 schema:affiliation https://www.grid.ac/institutes/grid.7700.0
153 schema:familyName Dunckelmann
154 schema:givenName R.
155 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0753751540.72
156 rdf:type schema:Person
157 https://www.grid.ac/institutes/grid.7700.0 schema:alternateName Heidelberg University
158 schema:name Department of General Paediatric, University of Heidelberg, Im Neuenheimer Feld 150, D-69120 Heidelberg, Germany, DE
159 Department of Neurology, University of Heidelberg, Im Neuenheimer Feld 150, D-69120 Heidelberg, Germany, DE
160 Department of Paediatric Neurology, University of Heidelberg, Im Neuenheimer Feld 150, D-69120 Heidelberg, Germany Tel.: +49-6221-562311 Fax: +49-6221-565744, DE
161 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...