The efficacy of nebulized salbutamol, magnesium sulfate, and salbutamol/magnesium sulfate combination in moderate bronchiolitis View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2014-09

AUTHORS

Mehmet Kose, Mehmet Adnan Ozturk, Hakan Poyrazoğlu, Tuba Elmas, Duygu Ekinci, Filiz Tubas, Tuba Kurt, Mehmet Akif Goktas

ABSTRACT

The aim of this paper is to compare the effect of nebulized magnesium sulfate to nebulized salbutamol and salbutamol/magnesium sulfate on successful discharge from the emergency department. A total of 56 infants were included in this double-blinded, prospective study. Infants were grouped according to the nebulized treatment they received: group 1-salbutamol/normal saline, group 2-magnesium sulfate and normal saline, and group 3-salbutamol plus magnesium sulfate. Heart beat, bronchiolitis, clinical severity scores (CSS), and oxygen saturation of the patients were determined before and after nebulization (0, 1, 4 h). The patients were monitored for adverse reactions. Post-treatment mean CSS results were significantly lower than pre-treatment scores in all groups at 4 h with no significant difference within groups. CSS scores were lower in the salbutamol/magnesium sulfate group when compared with the magnesium sulfate and salbutamol groups (3.4 (2.4-4.3), 4.7 (3.8-5.7), 4.0 (3.2-4.3)). CSS were significantly lower than those from the magnesium sulfate group. CONCLUSION: Nebulized magnesium sulfate plus salbutamol may have additive effects for improving the short-term CSS. More... »

PAGES

1157-1160

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00431-014-2309-3

DOI

http://dx.doi.org/10.1007/s00431-014-2309-3

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1001178427

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/24687251


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