Changes in grey matter development in autism spectrum disorder View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2013-07

AUTHORS

Ellen Greimel, Barbara Nehrkorn, Martin Schulte-Rüther, Gereon R. Fink, Thomas Nickl-Jockschat, Beate Herpertz-Dahlmann, Kerstin Konrad, Simon B. Eickhoff

ABSTRACT

Results on grey matter (GM) structural alterations in autism spectrum disorder (ASD) are inconclusive. Moreover, little is known about age effects on brain-structure abnormalities in ASD beyond childhood. Here, we aimed to examine regional GM volumes in a large sample of children, adolescents, and adults with ASD. Magnetic resonance imaging scans were obtained in 47 male ASD subjects and 51 matched healthy controls aged 8-50 years. We used whole-brain voxel-based morphometry to first assess group differences in regional GM volume across age. Moreover, taking a cross-sectional approach, group differences in age effects on regional GM volume were investigated. Compared to controls, ASD subjects showed reduced GM volumes in the anterior cingulate cortex, posterior superior temporal sulcus, and middle temporal gyrus. Investigation of group differences in age effects on regional GM volume revealed complex, region-specific alterations in ASD. While GM volumes in the amygdala, temporoparietal junction, septal nucleus and middle cingulate cortex increased in a negative quadratic fashion in both groups, data indicated that GM volume curves in ASD subjects were shifted to the left along the age axis. Moreover, while GM volume in the right precentral gyrus decreased linearly with age in ASD individuals, GM volume development in controls followed a U-shaped pattern. Based on a large sample, our voxel-based morphometry results on group differences in regional GM volumes help to resolve inconclusive findings from previous studies in ASD. Results on age-related changes of regional GM volumes suggest that ASD is characterized by complex alterations in lifetime trajectories of several brain regions that underpin social-cognitive and motor functions. More... »

PAGES

929-942

References to SciGraph publications

  • 2006-12. Regional gray matter volumetric changes in autism associated with social and repetitive behavior symptoms in BMC PSYCHIATRY
  • 2006-09. Minicolumnar abnormalities in autism in ACTA NEUROPATHOLOGICA
  • 2000-06. The Autism Diagnostic Observation Schedule—Generic: A Standard Measure of Social and Communication Deficits Associated with the Spectrum of Autism in JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS
  • 2010-06. Development of neural correlates of empathy from childhood to early adulthood: an fMRI study in boys and adult men in JOURNAL OF NEURAL TRANSMISSION
  • 2001-02. The Autism-Spectrum Quotient (AQ): Evidence from Asperger Syndrome/High-Functioning Autism, Malesand Females, Scientists and Mathematicians in JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS
  • 1996-02. Brief report: Planning problems in autism at the level of motor control in JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS
  • 1999-10. Brain development during childhood and adolescence: a longitudinal MRI study in NATURE NEUROSCIENCE
  • 1989-09. Autism diagnostic interview: A standardized investigator-based instrument in JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS
  • 2006-07. Motor Signs Distinguish Children with High Functioning Autism and Asperger’s Syndrome from Controls in JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS
  • 2003-03. Mapping cortical change across the human life span in NATURE NEUROSCIENCE
  • 2002-06. Reading the Mind in the Voice: A Study with Normal Adults and Adults with Asperger Syndrome and High Functioning Autism in JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS
  • 2008-03. Dissociation of Cognitive and Emotional Empathy in Adults with Asperger Syndrome Using the Multifaceted Empathy Test (MET) in JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS
  • 2009-06. Pilot evaluation of the Frankfurt Social Skills Training for children and adolescents with autism spectrum disorder in EUROPEAN CHILD & ADOLESCENT PSYCHIATRY
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s00429-012-0439-9

    DOI

    http://dx.doi.org/10.1007/s00429-012-0439-9

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1006312067

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/22777602


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