Resection of oesophageal and oesophagogastric junction cancer liver metastases — a summary of current evidence View Full Text


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Article Info

DATE

2021-12-03

AUTHORS

Andreas R. R. Weiss, Noel E. Donlon, Hans J. Schlitt, Christina Hackl

ABSTRACT

PurposeMetastatic oesophageal cancer is commonly considered as a palliative situation with a poor prognosis. However, there is increasing evidence that well-selected patients with a limited number of liver metastases (ECLM) may benefit from a multimodal approach including surgery.MethodsA systematic review of the current literature for randomized trials, retrospective studies, and case series with patients undergoing hepatectomies for oesophageal and oesophagogastric junction cancer liver metastases was conducted up to the 31st of August 2021 using the MEDLINE (PubMed) and Cochrane Library databases.ResultsA total of 661 articles were identified. After removal of duplicates, 483 articles were screened, of which 11 met the inclusion criteria. The available literature suggests that ECLM resection in patients with liver oligometastatic disease may lead to improved survival and even long-term survival in some cases. The response to concomitant chemotherapy and liver resection seems to be of significance. Furthermore, a long disease-free interval in metachronous disease, low number of liver metastases, young age, and good overall performance status have been described as potential predictive markers of outcome for the resection of liver metastases.ConclusionSurgery may be offered to carefully selected patients to potentially improve survival rates compared to palliative treatment approaches. Studies with standardized patient selection criteria and treatment protocols are required to further define the role for surgery in ECLM. In this context, particular consideration should be given to neoadjuvant treatment concepts including immunotherapies in stage IVB oesophageal and oesophagogastric junction cancer. More... »

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References to SciGraph publications

  • 2015-09-03. Prognosis and Treatment After Diagnosis of Recurrent Esophageal Carcinoma Following Esophagectomy with Curative Intent in ANNALS OF SURGICAL ONCOLOGY
  • 2012-11-10. Pattern of Postoperative Recurrence and Hepatic and/or Pulmonary Resection for Liver and/or Lung Metastases From Esophageal Carcinoma in WORLD JOURNAL OF SURGERY
  • 2017-03-16. Management of Neuroendocrine Tumor Liver Metastases: Long-Term Outcomes and Prognostic Factors from a Large Prospective Database in ANNALS OF SURGICAL ONCOLOGY
  • 2014-08-23. The benefits of liver resection for non-colorectal, non-neuroendocrine liver metastases: a systematic review in LANGENBECK'S ARCHIVES OF SURGERY
  • 2020-07-21. Modern oncological and operative outcomes in oesophageal cancer: the St. James’s hospital experience in IRISH JOURNAL OF MEDICAL SCIENCE
  • 2014-08-27. Response to Preoperative Chemotherapy Predicts Survival in Patients Undergoing Hepatectomy for Liver Metastases from Gastric and Esophageal Cancer in JOURNAL OF GASTROINTESTINAL SURGERY
  • 2014-05-06. Pulmonary Metastasectomy Secondary to Esophageal Carcinoma: Long-Term Survival and Prognostic Factors in ANNALS OF SURGICAL ONCOLOGY
  • 2017-01-04. Integrated genomic characterization of oesophageal carcinoma in NATURE
  • 2008-09-18. Results of a Multimodal Therapy in Patients with Stage IV Barrett’s Adenocarcinoma in WORLD JOURNAL OF SURGERY
  • 2017-12-28. The RENAISSANCE (AIO-FLOT5) trial: effect of chemotherapy alone vs. chemotherapy followed by surgical resection on survival and quality of life in patients with limited-metastatic adenocarcinoma of the stomach or esophagogastric junction – a phase III trial of the German AIO/CAO-V/CAOGI in BMC CANCER
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    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/34860291


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