Ontology type: schema:ScholarlyArticle
2021-11-29
AUTHORSSelcuk Gulmez, Erdal Polat, Ugur Duman, Aziz Serkan Senger, Orhan Uzun, Omer Ozduman, Ayhan Oz, Ismail Ege Subasi, Mustafa Duman
ABSTRACTPurposeThe hepatic bridge as an anatomical variation may lead to recurrence and treatment failure in cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) by constituting an obscure region during surgery. This report aimed to highlight the relationship between the hepatic bridge and various prognostic factors in peritoneal carcinomatosis.MethodsData of 101 patients who underwent CRS/HIPEC for peritoneal carcinomatosis in a single centre were retrospectively reviewed. Demographic characteristics, primary origin of peritoneal carcinomatosis, classification of hepatic bridge, Peritoneal Cancer Index (PCI) score, and completeness of cytoreduction (CC) score were analysed.ResultsThe tumour was proven histopathologically in 18 (28.6%) of 63 patients who underwent distal round ligament (DRL) resection. The PCI score was found to be significantly higher in patients with tumour in DRL compared to the ones without tumour (p < 0.001). The median PCI score of patients with implant positive DRL was 18 (12–20) and this score was 3 (2–6) for patients with implant negative DRL (p < 0.001). The ROC curve concerning the risk of an implant penetrating the round ligament revealed the optimal cut-off value of PCI at 10 with 88.9% sensitivity and 79.3% specificity.ConclusionThe round ligament should be removed, regardless of the PCI score, as a standard in mucinous adenocarcinoma of the appendix and malignant peritoneal mesothelioma. DRL should be removed when PCI is equal or higher than 10 for PC due to colorectal and ovarian cancers. More... »
PAGES1-7
http://scigraph.springernature.com/pub.10.1007/s00423-021-02386-4
DOIhttp://dx.doi.org/10.1007/s00423-021-02386-4
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PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/34845541
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