A propensity score matching study between conventional and soft fiber-optic choledochoscope guided percutaneous transhepatic cholangioscopic lithotripsy for treatment of cholelithiasis View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2021-11-26

AUTHORS

Hao Jin, Min Cui

ABSTRACT

BackgroundPercutaneous transhepatic cholangioscopic lithotripsy (PTCSL) provides an alternative method for cholelithiasis treatment. Since conventional rigid choledochoscope applied in PTCSL lacks high flexibility and high-resolution vision, we developed a new, soft fiber-optic choledochoscope (SFCS) to solve these problems.ObjectiveWe aim to verify the safety and efficacy of PTCSL guided by the newly developed choledochoscope, SCFS.MethodsIn this study, a total of 58 patients undergoing PTCSL from November, 2020 to December, 2020 in Zhuhai People’s Hospital were enrolled, including 32 patients undergoing conventional PTCSL and 26 patients undergoing SFCS-guided PTCSL. A method of propensity score matching was used in order to balance the pre-operative indexes of the two groups. As a result, a total of 21 pairs (1:1) were created. SFCS-guided PTCSL was performed on patients in the SFCS group for the treatment of cholelithiasis. The operation time, intraoperative blood loss, immediate clearance rate, final clearance rate, postoperative hospitalization time, postoperative complication rate, and recurrence rate were compared between the two groups. A 6-month follow-up was performed for the two groups.ResultsSFCS-guided PTCSL represents safe and effective treatment outcomes. The immediate clearance rate and final clearance rate in the SFCS group were significantly higher than that of the conventional group. Operation time, intraoperative blood loss, postoperative hospitalization days, and recurrence rate in the SFCS group were significantly lower than that of the conventional group.ConclusionsSFCS applied in PTCSL appears to be a safe and effective method for the treatment of cholelithiasis.This study has been registered in Chinese Clinical Trial Registry as required by legislation (Registration number: ChiCTR1800016864, Registration time: 2018/02/08). More... »

PAGES

675-683

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00423-021-02359-7

DOI

http://dx.doi.org/10.1007/s00423-021-02359-7

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1143206878

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/34825953


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