Recurrence patterns and their effects on clinical outcomes after R1 resection of colorectal liver metastases: a propensity score–matched analysis View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2021-05-24

AUTHORS

Nozomu Sakai, Katsunori Furukawa, Tsukasa Takayashiki, Satoshi Kuboki, Shigetsugu Takano, Masayuki Ohtsuka

ABSTRACT

PurposeThe prognostic significance of the surgical margin status remains controversial for patients who undergo hepatectomy for colorectal liver metastases. This study evaluated the influence of R1 resection on recurrence patterns and prognosis in these patients.MethodsBetween January 2001 and December 2016, 232 consecutive Japanese patients underwent initial hepatic resection for colorectal liver metastases. Their medical records were reviewed to evaluate recurrence and survival outcomes.ResultsRelative to patients with R0 resection, patients with R1 resection had significantly poorer recurrence-free survival (RFS) and overall survival (OS). However, after propensity score matching, there were no significant differences in RFS and OS associated with the margin status. Nevertheless, R1 resection was associated with a significantly higher incidence of intrahepatic recurrence and early recurrence, while R0 resection was associated with a significantly higher re-resection rate for hepatic recurrence. Only eight of 55 patients with R1 resection developed recurrence at the R1 resection margin, whereas 36 patients developed recurrence at other sites/organs.ConclusionAmong patients with similar characteristics, R1 resection does not affect long-term outcomes. This suggests that R1 resection itself is not a cause of a poor prognosis, but rather a potent indicator of aggressive tumor biology. More... »

PAGES

2739-2747

References to SciGraph publications

  • 2011-10-18. Outcome of Microscopic Incomplete Resection (R1) of Colorectal Liver Metastases in the Era of Neoadjuvant Chemotherapy in ANNALS OF SURGICAL ONCOLOGY
  • 2009-10-22. Resection Margin and Recurrence-Free Survival After Liver Resection of Colorectal Metastases in ANNALS OF SURGICAL ONCOLOGY
  • 2019-06-13. Survival Benefit of and Indications for Adjuvant Chemotherapy for Resected Colorectal Liver Metastases—a Japanese Nationwide Survey in JOURNAL OF GASTROINTESTINAL SURGERY
  • 2017-09-25. Repeated Resections of Hepatic and Pulmonary Metastases from Colorectal Cancer Provide Long-Term Survival in WORLD JOURNAL OF SURGERY
  • 2018-01-15. Colorectal cancer liver metastases – a population-based study on incidence, management and survival in BMC CANCER
  • 2014-10-18. Pulmonary Metastasectomy in Colorectal Cancer Patients with Previously Resected Liver Metastasis: Pooled Analysis in ANNALS OF SURGICAL ONCOLOGY
  • 2013-08-28. Prognostic Impact of Positive Surgical Margins After Resection of Colorectal Cancer Liver Metastases: Reappraisal in the Era of Modern Chemotherapy in WORLD JOURNAL OF SURGERY
  • 2016-01-12. Significance of R1 Resection for Advanced Colorectal Liver Metastases in the Era of Modern Effective Chemotherapy in WORLD JOURNAL OF SURGERY
  • 2014-03-11. Adjuvant therapy after resection of colorectal liver metastases: the predictive value of the MSKCC clinical risk score in the era of modern chemotherapy in BMC CANCER
  • 2015-12-29. Is Tumor Detachment from Vascular Structures Equivalent to R0 Resection in Surgery for Colorectal Liver Metastases? An Observational Cohort in ANNALS OF SURGICAL ONCOLOGY
  • 2016-09-30. KRAS Mutation Status Dictates Optimal Surgical Margin Width in Patients Undergoing Resection of Colorectal Liver Metastases in ANNALS OF SURGICAL ONCOLOGY
  • Identifiers

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    http://scigraph.springernature.com/pub.10.1007/s00423-021-02096-x

    DOI

    http://dx.doi.org/10.1007/s00423-021-02096-x

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1138301507

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/34031728


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