Elevated preoperative C-reactive protein levels are a risk factor for the development of postoperative infectious complications following elective colorectal surgery View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2013-08-29

AUTHORS

Toru Kubo, Satoshi Ono, Hideki Ueno, Eiji Shinto, Junji Yamamoto, Kazuo Hase

ABSTRACT

PurposeThe present study was designed to evaluate the relationship between the preoperative C-reactive protein levels and the incidence of postoperative infectious complications in patients undergoing colorectal surgery.MethodsThis study was a retrospective cohort study of a consecutive series of 464 patients who underwent elective colorectal resection between April 2010 and March 2012. We evaluated the patients’ preoperative conditions, including the preoperative C-reactive protein levels, surgical content, and incidence of postoperative infectious complications.ResultsPostoperative infectious complications occurred in 133 patients (28.7 %). In the univariate analysis, male gender, rectal surgery, open surgery, elevated preoperative white blood cell counts, elevated preoperative C-reactive protein levels, extended operative times, large amounts of blood loss during surgery, and ostomy formation were found to be significantly associated with the incidence of postoperative infectious complications. In the multivariate analysis, elevated preoperative C-reactive protein levels (OR per mg/dl = 1.17, 95 % CI = 1.02–1.37, P = 0.02) and large amounts of blood loss during surgery (OR per 100 g = 1.13, 95 % CI = 1.06–1.23, P < 0.01) were found to be independently associated with the incidence of postoperative infectious complications.ConclusionsThis study provides evidence of an association between the preoperative C-reactive protein level and the incidence of postoperative infectious complications following colorectal surgery, which should be further confirmed in prospective and appropriately designed studies. More... »

PAGES

965-971

References to SciGraph publications

  • 2009-03-24. Preoperative systemic inflammation predicts postoperative infectious complications in patients undergoing curative resection for colorectal cancer in BRITISH JOURNAL OF CANCER
  • 2012-02-21. Tumoral CRP expression in thoracic esophageal squamous cell cancers is associated with poor outcomes in SURGERY TODAY
  • 2000-09. Preoperative plasma plasminogen activator inhibitor type-1 and serum C-reactive protein levels in patients with colorectal cancer in ANNALS OF SURGICAL ONCOLOGY
  • 2005-02-08. The relationship between tumour T-lymphocyte infiltration, the systemic inflammatory response and survival in patients undergoing curative resection for colorectal cancer in BRITISH JOURNAL OF CANCER
  • 2007-10-09. Comparison of the prognostic value of selected markers of the systemic inflammatory response in patients with colorectal cancer in BRITISH JOURNAL OF CANCER
  • 2008-11-27. Impact of Postoperative Infection on Long-Term Survival After Potentially Curative Resection for Gastric Cancer in ANNALS OF SURGICAL ONCOLOGY
  • 2008-04-30. Risk factors associated with surgical site infection in upper and lower gastrointestinal surgery in SURGERY TODAY
  • 2008-11-21. Risk Factors of Surgical Site Infection After Hepatectomy for Liver Cancers in WORLD JOURNAL OF SURGERY
  • 2007-12-01. C-reactive protein as early predictor for infectious postoperative complications in rectal surgery in INTERNATIONAL JOURNAL OF COLORECTAL DISEASE
  • 2007-05-24. The Impact of Postoperative Complications on Long-Term Outcomes Following Curative Resection for Colorectal Cancer in ANNALS OF SURGICAL ONCOLOGY
  • 2007-11-22. Incidence, consequences, and risk factors for anastomotic dehiscence after colorectal surgery: a prospective monocentric study in INTERNATIONAL JOURNAL OF COLORECTAL DISEASE
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    http://scigraph.springernature.com/pub.10.1007/s00423-013-1107-0

    DOI

    http://dx.doi.org/10.1007/s00423-013-1107-0

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1039304825

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/23982867


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