Laparoscopic radioisotope-guided sentinel lymph node mapping and excision of the rectum—an experimental study View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2009-05

AUTHORS

S. Shah, A. Scholz, H. Reber, M. Schreckenberger, R. Viebahn, H. Lang, M. Korenkov

ABSTRACT

BACKGROUND: Patients with a low-risk T1 rectal carcinoma can undergo the therapy of a local excision. In these patients the lymph node (LN) status remains unknown. There is a potential risk of up to 7% for nodal metastasis. To investigate the possibility of using the sentinel lymph node (SLN) concept, an experimental study on pigs was undertaken. The objective was to laparoscopically identify and extract SLNs from the rectum using a radioisotope (RI). METHODS: The experiment was conducted in 30 pigs, since the sample size calculation indicated that with 30 animals a two-sided 95% confidence interval for a single proportion using the large sample normal approximation would extend at most 0.107 from the observed proportion of 0.9. One milliliter of a mixture of the RI Technetium 99 m (Tc99 m) and patent blue V dye was administered in the rectum endoscopically and after the lapse of 1 h, we laparoscopically identified and excised all SLNs using a laparoscopic gamma camera probe. RESULTS: We found in all operated pigs (n = 30) at least one SLN (lymph node with highest measured counts per second (cps)). In mean we detected 1.6 SLN (range one to three SLNs). In 28 cases, the SLN concept was successful. Sensitivity for detecting SLNs was 93% (n = 28/30), the probe count rate ranged from 600-10,000 cps with a median of 3,800. CONCLUSION: Minimal invasive mapping and excision of SLN of the rectum using a RI is feasible. The sensitivity for detecting SLN was high (93%). The application of this procedure on humans seems to be possible. More... »

PAGES

483-487

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00423-009-0477-9

DOI

http://dx.doi.org/10.1007/s00423-009-0477-9

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1004806989

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/19274469


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Coloring Agents", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Disease Models, Animal", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Gamma Cameras", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Laparoscopy", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Radionuclide Imaging", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Radiopharmaceuticals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Rectum", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Rosaniline Dyes", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Sensitivity and Specificity", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Sentinel Lymph Node Biopsy", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Swine", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Technetium Tc 99m Aggregated Albumin", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Ruhr University Bochum", 
          "id": "https://www.grid.ac/institutes/grid.5570.7", 
          "name": [
            "Department of Surgery, Knappschafts-Hospital, University of Bochum, In der Schornau 23\u201325, 44892, Bochum, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Shah", 
        "givenName": "S.", 
        "id": "sg:person.0626510165.59", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0626510165.59"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Johannes Gutenberg University of Mainz", 
          "id": "https://www.grid.ac/institutes/grid.5802.f", 
          "name": [
            "Department of Anesthesiology, University of Mainz, Mainz, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Scholz", 
        "givenName": "A.", 
        "id": "sg:person.0637274616.67", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0637274616.67"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Johannes Gutenberg University of Mainz", 
          "id": "https://www.grid.ac/institutes/grid.5802.f", 
          "name": [
            "Department of Nuclear medicine, University of Mainz, Mainz, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Reber", 
        "givenName": "H.", 
        "id": "sg:person.01156500711.09", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01156500711.09"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Johannes Gutenberg University of Mainz", 
          "id": "https://www.grid.ac/institutes/grid.5802.f", 
          "name": [
            "Department of Nuclear medicine, University of Mainz, Mainz, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Schreckenberger", 
        "givenName": "M.", 
        "id": "sg:person.011012064137.92", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011012064137.92"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Ruhr University Bochum", 
          "id": "https://www.grid.ac/institutes/grid.5570.7", 
          "name": [
            "Department of Surgery, Knappschafts-Hospital, University of Bochum, In der Schornau 23\u201325, 44892, Bochum, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Viebahn", 
        "givenName": "R.", 
        "id": "sg:person.01261171662.38", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01261171662.38"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Johannes Gutenberg University of Mainz", 
          "id": "https://www.grid.ac/institutes/grid.5802.f", 
          "name": [
            "Department of General and Abdominal Surgery, University of Mainz, Mainz, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lang", 
        "givenName": "H.", 
        "id": "sg:person.0657422174.53", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0657422174.53"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Johannes Gutenberg University of Mainz", 
          "id": "https://www.grid.ac/institutes/grid.5802.f", 
          "name": [
            "Department of General and Abdominal Surgery, University of Mainz, Mainz, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Korenkov", 
        "givenName": "M.", 
        "id": "sg:person.0630035720.54", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0630035720.54"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/bf02305790", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004389873", 
          "https://doi.org/10.1007/bf02305790"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf02305790", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004389873", 
          "https://doi.org/10.1007/bf02305790"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0959-8049(02)00058-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004483688"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s1055-3207(02)00005-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012425391"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10350-004-6453-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012578626", 
          "https://doi.org/10.1007/s10350-004-6453-0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1007/s10350-004-6453-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012578626"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/jso.10065", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013852516"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf02234796", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014394033", 
          "https://doi.org/10.1007/bf02234796"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1007/bf02234796", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014394033"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1007/bf02234796", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014394033"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s001040050646", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017076297", 
          "https://doi.org/10.1007/s001040050646"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00000658-199409000-00015", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025844838"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00000658-199409000-00015", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025844838"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/1097-0142(19891101)64:9<1937::aid-cncr2820640929>3.0.co;2-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026013475"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/archsurg.1992.01420040034005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027788056"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00130404-200211000-00008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028531661"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00130404-200211000-00008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028531661"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1148/radiol.2272011747", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033208601"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/bjs.1800600908", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034071250"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10350-005-0305-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036232405", 
          "https://doi.org/10.1007/s10350-005-0305-4"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1007/s10350-005-0305-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036232405"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00268-005-7867-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036764971", 
          "https://doi.org/10.1007/s00268-005-7867-0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00268-005-7867-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036764971", 
          "https://doi.org/10.1007/s00268-005-7867-0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf02237095", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041389457", 
          "https://doi.org/10.1007/bf02237095"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1007/bf02237095", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041389457"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1007/bf02237095", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041389457"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00423-007-0211-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043103737", 
          "https://doi.org/10.1007/s00423-007-0211-4"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00423-007-0211-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043103737", 
          "https://doi.org/10.1007/s00423-007-0211-4"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10434-000-0120-z", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049227818", 
          "https://doi.org/10.1007/s10434-000-0120-z"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0002-9610(82)90018-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049657483"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0002-9610(01)00658-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050623922"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2001.19.4.1128", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1074754835"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1075089937", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1076976974", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1077499695", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1083281245", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2009-05", 
    "datePublishedReg": "2009-05-01", 
    "description": "BACKGROUND: Patients with a low-risk T1 rectal carcinoma can undergo the therapy of a local excision. In these patients the lymph node (LN) status remains unknown. There is a potential risk of up to 7% for nodal metastasis. To investigate the possibility of using the sentinel lymph node (SLN) concept, an experimental study on pigs was undertaken. The objective was to laparoscopically identify and extract SLNs from the rectum using a radioisotope (RI).\nMETHODS: The experiment was conducted in 30 pigs, since the sample size calculation indicated that with 30 animals a two-sided 95% confidence interval for a single proportion using the large sample normal approximation would extend at most 0.107 from the observed proportion of 0.9. One milliliter of a mixture of the RI Technetium 99 m (Tc99 m) and patent blue V dye was administered in the rectum endoscopically and after the lapse of 1 h, we laparoscopically identified and excised all SLNs using a laparoscopic gamma camera probe.\nRESULTS: We found in all operated pigs (n = 30) at least one SLN (lymph node with highest measured counts per second (cps)). In mean we detected 1.6 SLN (range one to three SLNs). In 28 cases, the SLN concept was successful. Sensitivity for detecting SLNs was 93% (n = 28/30), the probe count rate ranged from 600-10,000 cps with a median of 3,800.\nCONCLUSION: Minimal invasive mapping and excision of SLN of the rectum using a RI is feasible. The sensitivity for detecting SLN was high (93%). The application of this procedure on humans seems to be possible.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s00423-009-0477-9", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1295031", 
        "issn": [
          "1435-2443", 
          "1435-2451"
        ], 
        "name": "Langenbeck's Archives of Surgery", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "3", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "394"
      }
    ], 
    "name": "Laparoscopic radioisotope-guided sentinel lymph node mapping and excision of the rectum\u2014an experimental study", 
    "pagination": "483-487", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "16e79d4a8ff004c5b67a4594b7fd93d8df6a1cbb360eb6c1e294629a7d6efcb3"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "19274469"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "9808285"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s00423-009-0477-9"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1004806989"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s00423-009-0477-9", 
      "https://app.dimensions.ai/details/publication/pub.1004806989"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T14:27", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000373_0000000373/records_13078_00000000.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1007/s00423-009-0477-9"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00423-009-0477-9'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00423-009-0477-9'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00423-009-0477-9'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00423-009-0477-9'


 

This table displays all metadata directly associated to this object as RDF triples.

260 TRIPLES      21 PREDICATES      71 URIs      34 LITERALS      22 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s00423-009-0477-9 schema:about N10fd6c9ac3124ffa8197b4b948451930
2 N1b92fe9e41e048f9b357ba1e49d50ad7
3 N4e2fd58eba70435d9a448a0339304779
4 N5fb67209be864240919cfeb4a3451565
5 N692a3d266d1b4bc4a24d89e9ded716ba
6 N72c85a29c9db41cb8bb26357e0985a6a
7 N97548decd67b4986b9da5155f37f5f8e
8 Na17b5da641dc4968beb70e0e4b68028b
9 Na5ba49e1b0974bef8a9756b660f02805
10 Nbb24f4ad271b4d1299c82fa5d5deba08
11 Nbbba20aba57641dcb0fc9c7c93f74a87
12 Nc118252876974ebe8017300368fd9903
13 Nf020b5983cd9457fb7f2e76591fcf7c3
14 anzsrc-for:11
15 anzsrc-for:1103
16 schema:author N18b64286fb4f43b5a3693deb024fac4f
17 schema:citation sg:pub.10.1007/bf02234796
18 sg:pub.10.1007/bf02237095
19 sg:pub.10.1007/bf02305790
20 sg:pub.10.1007/s001040050646
21 sg:pub.10.1007/s00268-005-7867-0
22 sg:pub.10.1007/s00423-007-0211-4
23 sg:pub.10.1007/s10350-004-6453-0
24 sg:pub.10.1007/s10350-005-0305-4
25 sg:pub.10.1007/s10434-000-0120-z
26 https://app.dimensions.ai/details/publication/pub.1075089937
27 https://app.dimensions.ai/details/publication/pub.1076976974
28 https://app.dimensions.ai/details/publication/pub.1077499695
29 https://app.dimensions.ai/details/publication/pub.1083281245
30 https://doi.org/10.1001/archsurg.1992.01420040034005
31 https://doi.org/10.1002/1097-0142(19891101)64:9<1937::aid-cncr2820640929>3.0.co;2-x
32 https://doi.org/10.1002/bjs.1800600908
33 https://doi.org/10.1002/jso.10065
34 https://doi.org/10.1007/bf02234796
35 https://doi.org/10.1007/bf02237095
36 https://doi.org/10.1007/s10350-004-6453-0
37 https://doi.org/10.1007/s10350-005-0305-4
38 https://doi.org/10.1016/0002-9610(82)90018-6
39 https://doi.org/10.1016/s0002-9610(01)00658-4
40 https://doi.org/10.1016/s0959-8049(02)00058-8
41 https://doi.org/10.1016/s1055-3207(02)00005-4
42 https://doi.org/10.1097/00000658-199409000-00015
43 https://doi.org/10.1097/00130404-200211000-00008
44 https://doi.org/10.1148/radiol.2272011747
45 https://doi.org/10.1200/jco.2001.19.4.1128
46 schema:datePublished 2009-05
47 schema:datePublishedReg 2009-05-01
48 schema:description BACKGROUND: Patients with a low-risk T1 rectal carcinoma can undergo the therapy of a local excision. In these patients the lymph node (LN) status remains unknown. There is a potential risk of up to 7% for nodal metastasis. To investigate the possibility of using the sentinel lymph node (SLN) concept, an experimental study on pigs was undertaken. The objective was to laparoscopically identify and extract SLNs from the rectum using a radioisotope (RI). METHODS: The experiment was conducted in 30 pigs, since the sample size calculation indicated that with 30 animals a two-sided 95% confidence interval for a single proportion using the large sample normal approximation would extend at most 0.107 from the observed proportion of 0.9. One milliliter of a mixture of the RI Technetium 99 m (Tc99 m) and patent blue V dye was administered in the rectum endoscopically and after the lapse of 1 h, we laparoscopically identified and excised all SLNs using a laparoscopic gamma camera probe. RESULTS: We found in all operated pigs (n = 30) at least one SLN (lymph node with highest measured counts per second (cps)). In mean we detected 1.6 SLN (range one to three SLNs). In 28 cases, the SLN concept was successful. Sensitivity for detecting SLNs was 93% (n = 28/30), the probe count rate ranged from 600-10,000 cps with a median of 3,800. CONCLUSION: Minimal invasive mapping and excision of SLN of the rectum using a RI is feasible. The sensitivity for detecting SLN was high (93%). The application of this procedure on humans seems to be possible.
49 schema:genre research_article
50 schema:inLanguage en
51 schema:isAccessibleForFree false
52 schema:isPartOf N62f6cfb35f0b41adb65083bb1ca18367
53 Na2757cc4540246dfbd0b62ac9a3651a1
54 sg:journal.1295031
55 schema:name Laparoscopic radioisotope-guided sentinel lymph node mapping and excision of the rectum—an experimental study
56 schema:pagination 483-487
57 schema:productId N49d9375b5de74ef3a89bec1f4b815d04
58 N6565a0e0046943b1a34e0bdc6fdd9ad3
59 Nabbaaabbd6df412db6e7f715b446011d
60 Nc650033aa03842a1a3ad8b44a3fea91c
61 Ne2501f43202e46b9af054c4d0ac7c47c
62 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004806989
63 https://doi.org/10.1007/s00423-009-0477-9
64 schema:sdDatePublished 2019-04-11T14:27
65 schema:sdLicense https://scigraph.springernature.com/explorer/license/
66 schema:sdPublisher N5136be7be8a24088a1d68e4f171a0823
67 schema:url http://link.springer.com/10.1007/s00423-009-0477-9
68 sgo:license sg:explorer/license/
69 sgo:sdDataset articles
70 rdf:type schema:ScholarlyArticle
71 N10fd6c9ac3124ffa8197b4b948451930 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
72 schema:name Radiopharmaceuticals
73 rdf:type schema:DefinedTerm
74 N18b64286fb4f43b5a3693deb024fac4f rdf:first sg:person.0626510165.59
75 rdf:rest N26e424ca784644339f22d12eb107d3c1
76 N1944050d87ec43a3b18d10eaa33a1c6b rdf:first sg:person.0657422174.53
77 rdf:rest Neb5c2f610168441f8350f57ba903eafd
78 N1b92fe9e41e048f9b357ba1e49d50ad7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
79 schema:name Swine
80 rdf:type schema:DefinedTerm
81 N26e424ca784644339f22d12eb107d3c1 rdf:first sg:person.0637274616.67
82 rdf:rest N2be6c33b473e45b88bad686beaa187a2
83 N2be6c33b473e45b88bad686beaa187a2 rdf:first sg:person.01156500711.09
84 rdf:rest N667f16a154714055aa76a9abaabfbc5d
85 N49d9375b5de74ef3a89bec1f4b815d04 schema:name dimensions_id
86 schema:value pub.1004806989
87 rdf:type schema:PropertyValue
88 N4e2fd58eba70435d9a448a0339304779 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
89 schema:name Sentinel Lymph Node Biopsy
90 rdf:type schema:DefinedTerm
91 N5136be7be8a24088a1d68e4f171a0823 schema:name Springer Nature - SN SciGraph project
92 rdf:type schema:Organization
93 N5fb67209be864240919cfeb4a3451565 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
94 schema:name Sensitivity and Specificity
95 rdf:type schema:DefinedTerm
96 N62f6cfb35f0b41adb65083bb1ca18367 schema:issueNumber 3
97 rdf:type schema:PublicationIssue
98 N6565a0e0046943b1a34e0bdc6fdd9ad3 schema:name nlm_unique_id
99 schema:value 9808285
100 rdf:type schema:PropertyValue
101 N667f16a154714055aa76a9abaabfbc5d rdf:first sg:person.011012064137.92
102 rdf:rest Na23b72ca7cbc4230b20d41f297113c09
103 N692a3d266d1b4bc4a24d89e9ded716ba schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
104 schema:name Disease Models, Animal
105 rdf:type schema:DefinedTerm
106 N72c85a29c9db41cb8bb26357e0985a6a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
107 schema:name Radionuclide Imaging
108 rdf:type schema:DefinedTerm
109 N97548decd67b4986b9da5155f37f5f8e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
110 schema:name Rosaniline Dyes
111 rdf:type schema:DefinedTerm
112 Na17b5da641dc4968beb70e0e4b68028b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
113 schema:name Technetium Tc 99m Aggregated Albumin
114 rdf:type schema:DefinedTerm
115 Na23b72ca7cbc4230b20d41f297113c09 rdf:first sg:person.01261171662.38
116 rdf:rest N1944050d87ec43a3b18d10eaa33a1c6b
117 Na2757cc4540246dfbd0b62ac9a3651a1 schema:volumeNumber 394
118 rdf:type schema:PublicationVolume
119 Na5ba49e1b0974bef8a9756b660f02805 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
120 schema:name Coloring Agents
121 rdf:type schema:DefinedTerm
122 Nabbaaabbd6df412db6e7f715b446011d schema:name doi
123 schema:value 10.1007/s00423-009-0477-9
124 rdf:type schema:PropertyValue
125 Nbb24f4ad271b4d1299c82fa5d5deba08 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
126 schema:name Laparoscopy
127 rdf:type schema:DefinedTerm
128 Nbbba20aba57641dcb0fc9c7c93f74a87 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
129 schema:name Gamma Cameras
130 rdf:type schema:DefinedTerm
131 Nc118252876974ebe8017300368fd9903 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
132 schema:name Animals
133 rdf:type schema:DefinedTerm
134 Nc650033aa03842a1a3ad8b44a3fea91c schema:name pubmed_id
135 schema:value 19274469
136 rdf:type schema:PropertyValue
137 Ne2501f43202e46b9af054c4d0ac7c47c schema:name readcube_id
138 schema:value 16e79d4a8ff004c5b67a4594b7fd93d8df6a1cbb360eb6c1e294629a7d6efcb3
139 rdf:type schema:PropertyValue
140 Neb5c2f610168441f8350f57ba903eafd rdf:first sg:person.0630035720.54
141 rdf:rest rdf:nil
142 Nf020b5983cd9457fb7f2e76591fcf7c3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
143 schema:name Rectum
144 rdf:type schema:DefinedTerm
145 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
146 schema:name Medical and Health Sciences
147 rdf:type schema:DefinedTerm
148 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
149 schema:name Clinical Sciences
150 rdf:type schema:DefinedTerm
151 sg:journal.1295031 schema:issn 1435-2443
152 1435-2451
153 schema:name Langenbeck's Archives of Surgery
154 rdf:type schema:Periodical
155 sg:person.011012064137.92 schema:affiliation https://www.grid.ac/institutes/grid.5802.f
156 schema:familyName Schreckenberger
157 schema:givenName M.
158 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011012064137.92
159 rdf:type schema:Person
160 sg:person.01156500711.09 schema:affiliation https://www.grid.ac/institutes/grid.5802.f
161 schema:familyName Reber
162 schema:givenName H.
163 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01156500711.09
164 rdf:type schema:Person
165 sg:person.01261171662.38 schema:affiliation https://www.grid.ac/institutes/grid.5570.7
166 schema:familyName Viebahn
167 schema:givenName R.
168 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01261171662.38
169 rdf:type schema:Person
170 sg:person.0626510165.59 schema:affiliation https://www.grid.ac/institutes/grid.5570.7
171 schema:familyName Shah
172 schema:givenName S.
173 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0626510165.59
174 rdf:type schema:Person
175 sg:person.0630035720.54 schema:affiliation https://www.grid.ac/institutes/grid.5802.f
176 schema:familyName Korenkov
177 schema:givenName M.
178 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0630035720.54
179 rdf:type schema:Person
180 sg:person.0637274616.67 schema:affiliation https://www.grid.ac/institutes/grid.5802.f
181 schema:familyName Scholz
182 schema:givenName A.
183 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0637274616.67
184 rdf:type schema:Person
185 sg:person.0657422174.53 schema:affiliation https://www.grid.ac/institutes/grid.5802.f
186 schema:familyName Lang
187 schema:givenName H.
188 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0657422174.53
189 rdf:type schema:Person
190 sg:pub.10.1007/bf02234796 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014394033
191 https://doi.org/10.1007/bf02234796
192 rdf:type schema:CreativeWork
193 sg:pub.10.1007/bf02237095 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041389457
194 https://doi.org/10.1007/bf02237095
195 rdf:type schema:CreativeWork
196 sg:pub.10.1007/bf02305790 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004389873
197 https://doi.org/10.1007/bf02305790
198 rdf:type schema:CreativeWork
199 sg:pub.10.1007/s001040050646 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017076297
200 https://doi.org/10.1007/s001040050646
201 rdf:type schema:CreativeWork
202 sg:pub.10.1007/s00268-005-7867-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036764971
203 https://doi.org/10.1007/s00268-005-7867-0
204 rdf:type schema:CreativeWork
205 sg:pub.10.1007/s00423-007-0211-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043103737
206 https://doi.org/10.1007/s00423-007-0211-4
207 rdf:type schema:CreativeWork
208 sg:pub.10.1007/s10350-004-6453-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012578626
209 https://doi.org/10.1007/s10350-004-6453-0
210 rdf:type schema:CreativeWork
211 sg:pub.10.1007/s10350-005-0305-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036232405
212 https://doi.org/10.1007/s10350-005-0305-4
213 rdf:type schema:CreativeWork
214 sg:pub.10.1007/s10434-000-0120-z schema:sameAs https://app.dimensions.ai/details/publication/pub.1049227818
215 https://doi.org/10.1007/s10434-000-0120-z
216 rdf:type schema:CreativeWork
217 https://app.dimensions.ai/details/publication/pub.1075089937 schema:CreativeWork
218 https://app.dimensions.ai/details/publication/pub.1076976974 schema:CreativeWork
219 https://app.dimensions.ai/details/publication/pub.1077499695 schema:CreativeWork
220 https://app.dimensions.ai/details/publication/pub.1083281245 schema:CreativeWork
221 https://doi.org/10.1001/archsurg.1992.01420040034005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027788056
222 rdf:type schema:CreativeWork
223 https://doi.org/10.1002/1097-0142(19891101)64:9<1937::aid-cncr2820640929>3.0.co;2-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1026013475
224 rdf:type schema:CreativeWork
225 https://doi.org/10.1002/bjs.1800600908 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034071250
226 rdf:type schema:CreativeWork
227 https://doi.org/10.1002/jso.10065 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013852516
228 rdf:type schema:CreativeWork
229 https://doi.org/10.1007/bf02234796 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014394033
230 rdf:type schema:CreativeWork
231 https://doi.org/10.1007/bf02237095 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041389457
232 rdf:type schema:CreativeWork
233 https://doi.org/10.1007/s10350-004-6453-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012578626
234 rdf:type schema:CreativeWork
235 https://doi.org/10.1007/s10350-005-0305-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036232405
236 rdf:type schema:CreativeWork
237 https://doi.org/10.1016/0002-9610(82)90018-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049657483
238 rdf:type schema:CreativeWork
239 https://doi.org/10.1016/s0002-9610(01)00658-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050623922
240 rdf:type schema:CreativeWork
241 https://doi.org/10.1016/s0959-8049(02)00058-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004483688
242 rdf:type schema:CreativeWork
243 https://doi.org/10.1016/s1055-3207(02)00005-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012425391
244 rdf:type schema:CreativeWork
245 https://doi.org/10.1097/00000658-199409000-00015 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025844838
246 rdf:type schema:CreativeWork
247 https://doi.org/10.1097/00130404-200211000-00008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028531661
248 rdf:type schema:CreativeWork
249 https://doi.org/10.1148/radiol.2272011747 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033208601
250 rdf:type schema:CreativeWork
251 https://doi.org/10.1200/jco.2001.19.4.1128 schema:sameAs https://app.dimensions.ai/details/publication/pub.1074754835
252 rdf:type schema:CreativeWork
253 https://www.grid.ac/institutes/grid.5570.7 schema:alternateName Ruhr University Bochum
254 schema:name Department of Surgery, Knappschafts-Hospital, University of Bochum, In der Schornau 23–25, 44892, Bochum, Germany
255 rdf:type schema:Organization
256 https://www.grid.ac/institutes/grid.5802.f schema:alternateName Johannes Gutenberg University of Mainz
257 schema:name Department of Anesthesiology, University of Mainz, Mainz, Germany
258 Department of General and Abdominal Surgery, University of Mainz, Mainz, Germany
259 Department of Nuclear medicine, University of Mainz, Mainz, Germany
260 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...