Modified radical lymphadenectomy (D1.5) for T2–3 gastric cancer View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2005-07-22

AUTHORS

Takashi Ichikura, Kentaro Chochi, Hidekazu Sugasawa, Hidetaka Mochizuki

ABSTRACT

BackgroundThe operative mortality in gastric cancer surgery has been reported to be higher with D2 lymphadenectomy than with D1 in the West. The modified radical lymphadenectomy (D1.5) may be safer than D2 under these circumstances. This study was aimed to determine whether D1.5 would deteriorate long-term survival as compared with D2.MethodSince the concept of the extent of lymphadenectomy varied among the surgeons, 461 patients who underwent curative gastrectomy for T2–4 gastric adenocarcinoma were retrospectively categorized into three groups according to the surgeon: D1 with dissection along the left gastric and common hepatic arteries (D1.5); lymphadenectomy between D1.5 and D2; D2 or more extended dissection.ResultsNo differences were found in the survival rates among the three groups within each of the T2a, T2b, and T3 categories. According to a multivariate analysis using Cox’s proportional hazard model, the classification according to the surgeons had no survival impact (p>0.8).ConclusionD1.5 lymphadenectomy resulted in a survival rate that was almost equal to that of D2. The use of D1.5 instead of D2 can be an attractive option to be compared with D1 in future trials. More... »

PAGES

397-402

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00423-005-0570-7

DOI

http://dx.doi.org/10.1007/s00423-005-0570-7

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1007903848

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/16041552


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