Concomitant external pneumatic compression treatment with consecutive days of high intensity interval training reduces markers of proteolysis View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2017-10-26

AUTHORS

Cody T. Haun, Michael D. Roberts, Matthew A. Romero, Shelby C. Osburn, James C. Healy, Angelique N. Moore, Christopher B. Mobley, Paul A. Roberson, Wesley C. Kephart, Petey W. Mumford, Michael D. Goodlett, David D. Pascoe, Jeffrey S. Martin

ABSTRACT

PurposeTo compare the effects of external pneumatic compression (EPC) and sham when used concurrently with high intensity interval training (HIIT) on performance-related outcomes and recovery-related molecular measures.MethodsEighteen recreationally endurance-trained male participants (age: 21.6 ± 2.4 years, BMI: 25.7 ± 0.5 kg/m2, VO2peak: 51.3 ± 0.9 mL/kg/min) were randomized to balanced sham and EPC treatment groups. Three consecutive days of HIIT followed by EPC/sham treatment (Days 2–4) and 3 consecutive days of recovery (Days 5–7) with EPC/sham only on Days 5–6 were employed. Venipuncture, flexibility and pressure-to-pain threshold (PPT) measurements were made throughout. Vastus lateralis muscle was biopsied at PRE (i.e., Day 1), 1-h post-EPC/sham treatment on Day 2 (POST1), and 24-h post-EPC/sham treatment on Day 7 (POST2). 6-km run time trial performance was tested at PRE and POST2.ResultsNo group × time interaction was observed for flexibility, PPT, or serum measures of creatine kinase (CK), hsCRP, and 8-isoprostane. However, there was a main effect of time for serum CK (p = 0.005). Change from PRE in 6-km run times at POST2 were not significantly different between groups. Significant between-groups differences existed for change from PRE in atrogin-1 mRNA (p = 0.018) at the POST1 time point (EPC: − 19.7 ± 8.1%, sham: + 7.7 ± 5.9%) and atrogin-1 protein concentration (p = 0.013) at the POST2 time point (EPC: − 31.8 ± 7.5%, sham: + 96.0 ± 34.7%). In addition, change from PRE in poly-Ub proteins was significantly different between groups at both the POST1 (EPC: − 26.0 ± 10.3%, sham: + 34.8 ± 28.5%; p = 0.046) and POST2 (EPC: − 33.7 ± 17.2%, sham: + 21.4 ± 14.9%; p = 0.037) time points.ConclusionsEPC when used concurrently with HIIT and in subsequent recovery days reduces skeletal muscle markers of proteolysis. More... »

PAGES

2587-2600

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00421-017-3746-2

DOI

http://dx.doi.org/10.1007/s00421-017-3746-2

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1092403878

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/29075862


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adult", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "C-Reactive Protein", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Creatine Kinase", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Dinoprost", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "High-Intensity Interval Training", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Intermittent Pneumatic Compression Devices", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Muscle Proteins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Proteolysis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Quadriceps Muscle", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "SKP Cullin F-Box Protein Ligases", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Ubiquitination", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "School of Kinesiology, Auburn University, Auburn, AL, USA", 
          "id": "http://www.grid.ac/institutes/grid.252546.2", 
          "name": [
            "School of Kinesiology, Auburn University, Auburn, AL, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Haun", 
        "givenName": "Cody T.", 
        "id": "sg:person.014650750541.38", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014650750541.38"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Cell Biology and Physiology, Edward Via College of Osteopathic Medicine, Auburn Campus, 910 S. Donahue Drive, 36832, Auburn, AL, USA", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "School of Kinesiology, Auburn University, Auburn, AL, USA", 
            "Department of Cell Biology and Physiology, Edward Via College of Osteopathic Medicine, Auburn Campus, 910 S. Donahue Drive, 36832, Auburn, AL, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Roberts", 
        "givenName": "Michael D.", 
        "id": "sg:person.01366257433.24", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01366257433.24"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "School of Kinesiology, Auburn University, Auburn, AL, USA", 
          "id": "http://www.grid.ac/institutes/grid.252546.2", 
          "name": [
            "School of Kinesiology, Auburn University, Auburn, AL, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Romero", 
        "givenName": "Matthew A.", 
        "id": "sg:person.015561661163.44", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015561661163.44"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "School of Kinesiology, Auburn University, Auburn, AL, USA", 
          "id": "http://www.grid.ac/institutes/grid.252546.2", 
          "name": [
            "School of Kinesiology, Auburn University, Auburn, AL, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Osburn", 
        "givenName": "Shelby C.", 
        "id": "sg:person.016357241563.51", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016357241563.51"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Cell Biology and Physiology, Edward Via College of Osteopathic Medicine, Auburn Campus, 910 S. Donahue Drive, 36832, Auburn, AL, USA", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Department of Cell Biology and Physiology, Edward Via College of Osteopathic Medicine, Auburn Campus, 910 S. Donahue Drive, 36832, Auburn, AL, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Healy", 
        "givenName": "James C.", 
        "id": "sg:person.01350325772.02", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01350325772.02"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "College of Human Sciences, Auburn University, 36849, Auburn, AL, USA", 
          "id": "http://www.grid.ac/institutes/grid.252546.2", 
          "name": [
            "Department of Cell Biology and Physiology, Edward Via College of Osteopathic Medicine, Auburn Campus, 910 S. Donahue Drive, 36832, Auburn, AL, USA", 
            "College of Human Sciences, Auburn University, 36849, Auburn, AL, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Moore", 
        "givenName": "Angelique N.", 
        "id": "sg:person.013021022047.78", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013021022047.78"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "School of Kinesiology, Auburn University, Auburn, AL, USA", 
          "id": "http://www.grid.ac/institutes/grid.252546.2", 
          "name": [
            "School of Kinesiology, Auburn University, Auburn, AL, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Mobley", 
        "givenName": "Christopher B.", 
        "id": "sg:person.01154064651.37", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01154064651.37"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "School of Kinesiology, Auburn University, Auburn, AL, USA", 
          "id": "http://www.grid.ac/institutes/grid.252546.2", 
          "name": [
            "School of Kinesiology, Auburn University, Auburn, AL, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Roberson", 
        "givenName": "Paul A.", 
        "id": "sg:person.011121607313.63", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011121607313.63"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "School of Kinesiology, Auburn University, Auburn, AL, USA", 
          "id": "http://www.grid.ac/institutes/grid.252546.2", 
          "name": [
            "School of Kinesiology, Auburn University, Auburn, AL, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kephart", 
        "givenName": "Wesley C.", 
        "id": "sg:person.01105751451.72", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01105751451.72"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "School of Kinesiology, Auburn University, Auburn, AL, USA", 
          "id": "http://www.grid.ac/institutes/grid.252546.2", 
          "name": [
            "School of Kinesiology, Auburn University, Auburn, AL, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Mumford", 
        "givenName": "Petey W.", 
        "id": "sg:person.01062370067.57", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01062370067.57"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Athletics Department, Auburn University, Auburn, AL, USA", 
          "id": "http://www.grid.ac/institutes/grid.252546.2", 
          "name": [
            "Department of Cell Biology and Physiology, Edward Via College of Osteopathic Medicine, Auburn Campus, 910 S. Donahue Drive, 36832, Auburn, AL, USA", 
            "Athletics Department, Auburn University, Auburn, AL, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Goodlett", 
        "givenName": "Michael D.", 
        "id": "sg:person.0661135551.43", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0661135551.43"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "School of Kinesiology, Auburn University, Auburn, AL, USA", 
          "id": "http://www.grid.ac/institutes/grid.252546.2", 
          "name": [
            "School of Kinesiology, Auburn University, Auburn, AL, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Pascoe", 
        "givenName": "David D.", 
        "id": "sg:person.01270313251.04", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01270313251.04"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Cell Biology and Physiology, Edward Via College of Osteopathic Medicine, Auburn Campus, 910 S. Donahue Drive, 36832, Auburn, AL, USA", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "School of Kinesiology, Auburn University, Auburn, AL, USA", 
            "Department of Cell Biology and Physiology, Edward Via College of Osteopathic Medicine, Auburn Campus, 910 S. Donahue Drive, 36832, Auburn, AL, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Martin", 
        "givenName": "Jeffrey S.", 
        "id": "sg:person.012143622537.90", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012143622537.90"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/s00421-015-3187-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041197553", 
          "https://doi.org/10.1007/s00421-015-3187-8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00726-010-0765-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031819481", 
          "https://doi.org/10.1007/s00726-010-0765-2"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.2165/00007256-200333020-00005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029092051", 
          "https://doi.org/10.2165/00007256-200333020-00005"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00421-003-0857-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052682625", 
          "https://doi.org/10.1007/s00421-003-0857-8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nprot.2008.73", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005355981", 
          "https://doi.org/10.1038/nprot.2008.73"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2017-10-26", 
    "datePublishedReg": "2017-10-26", 
    "description": "PurposeTo compare the effects of external pneumatic compression (EPC) and sham when used concurrently with high intensity interval training (HIIT) on performance-related outcomes and recovery-related molecular measures.MethodsEighteen recreationally endurance-trained male participants (age: 21.6\u2009\u00b1\u20092.4\u00a0years, BMI: 25.7\u2009\u00b1\u20090.5\u00a0kg/m2, VO2peak: 51.3\u2009\u00b1\u20090.9\u00a0mL/kg/min) were randomized to balanced sham and EPC treatment groups. Three consecutive days of HIIT followed by EPC/sham treatment (Days 2\u20134) and 3 consecutive days of recovery (Days 5\u20137) with EPC/sham only on Days 5\u20136 were employed. Venipuncture, flexibility and pressure-to-pain threshold (PPT) measurements were made throughout. Vastus lateralis muscle was biopsied at PRE (i.e., Day 1), 1-h post-EPC/sham treatment on Day 2 (POST1), and 24-h post-EPC/sham treatment on Day 7 (POST2). 6-km run time trial performance was tested at PRE and POST2.ResultsNo group\u2009\u00d7\u2009time interaction was observed for flexibility, PPT, or serum measures of creatine kinase (CK), hsCRP, and 8-isoprostane. However, there was a main effect of time for serum CK (p\u2009=\u20090.005). Change from PRE in 6-km run times at POST2 were not significantly different between groups. Significant between-groups differences existed for change from PRE in atrogin-1 mRNA (p\u2009=\u20090.018) at the POST1 time point (EPC: \u2212\u200919.7\u2009\u00b1\u20098.1%, sham: +\u20097.7\u2009\u00b1\u20095.9%) and atrogin-1 protein concentration (p\u2009=\u20090.013) at the POST2 time point (EPC: \u2212\u200931.8\u2009\u00b1\u20097.5%, sham: +\u00a096.0\u2009\u00b1\u200934.7%). In addition, change from PRE in poly-Ub proteins was significantly different between groups at both the POST1 (EPC: \u2212\u200926.0\u2009\u00b1\u200910.3%, sham: +\u00a034.8\u2009\u00b1\u200928.5%; p\u2009=\u20090.046) and POST2 (EPC: \u2212\u00a033.7\u2009\u00b1\u200917.2%, sham: +\u200921.4\u2009\u00b1\u200914.9%; p\u2009=\u20090.037) time points.ConclusionsEPC when used concurrently with HIIT and in subsequent recovery days reduces skeletal muscle markers of proteolysis.", 
    "genre": "article", 
    "id": "sg:pub.10.1007/s00421-017-3746-2", 
    "inLanguage": "en", 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1319730", 
        "issn": [
          "1439-6319", 
          "1432-1025"
        ], 
        "name": "European Journal of Applied Physiology", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "12", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "117"
      }
    ], 
    "keywords": [
      "high intensity interval training", 
      "external pneumatic compression", 
      "intensity interval training", 
      "sham treatment", 
      "consecutive days", 
      "creatine kinase", 
      "interval training", 
      "time points", 
      "markers of proteolysis", 
      "pain threshold measurements", 
      "serum creatine kinase", 
      "vastus lateralis muscle", 
      "time trial performance", 
      "skeletal muscle markers", 
      "subsequent recovery days", 
      "pneumatic compression", 
      "serum measures", 
      "treatment groups", 
      "lateralis muscle", 
      "day 2", 
      "day 5", 
      "day 7", 
      "atrogin-1 mRNA", 
      "recovery days", 
      "muscle markers", 
      "sham", 
      "compression treatment", 
      "trial performance", 
      "time interaction", 
      "group differences", 
      "male participants", 
      "treatment", 
      "days", 
      "pre", 
      "threshold measurements", 
      "group", 
      "markers", 
      "protein concentration", 
      "hsCRP", 
      "molecular measures", 
      "venipuncture", 
      "PurposeTo", 
      "muscle", 
      "main effect", 
      "POST1", 
      "outcomes", 
      "POST2", 
      "MethodsEighteen", 
      "changes", 
      "training", 
      "measures", 
      "effect", 
      "participants", 
      "mRNA", 
      "proteolysis", 
      "performance-related outcomes", 
      "kinase", 
      "recovery", 
      "differences", 
      "time", 
      "protein", 
      "pressure", 
      "concentration", 
      "ppt", 
      "addition", 
      "point", 
      "compression", 
      "measurements", 
      "interaction", 
      "run time", 
      "performance", 
      "flexibility", 
      "recovery-related molecular measures", 
      "endurance-trained male participants", 
      "balanced sham", 
      "EPC treatment groups", 
      "EPC/sham treatment", 
      "EPC/sham", 
      "POST1 time point", 
      "atrogin-1 protein concentration", 
      "POST2 time point", 
      "poly-Ub proteins", 
      "ConclusionsEPC", 
      "Concomitant external pneumatic compression treatment", 
      "external pneumatic compression treatment", 
      "pneumatic compression treatment"
    ], 
    "name": "Concomitant external pneumatic compression treatment with consecutive days of high intensity interval training reduces markers of proteolysis", 
    "pagination": "2587-2600", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1092403878"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s00421-017-3746-2"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "29075862"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s00421-017-3746-2", 
      "https://app.dimensions.ai/details/publication/pub.1092403878"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2021-11-01T18:31", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20211101/entities/gbq_results/article/article_740.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1007/s00421-017-3746-2"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00421-017-3746-2'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00421-017-3746-2'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00421-017-3746-2'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00421-017-3746-2'


 

This table displays all metadata directly associated to this object as RDF triples.

313 TRIPLES      22 PREDICATES      130 URIs      117 LITERALS      20 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s00421-017-3746-2 schema:about N015933377fb940e59f5b3d95933cff9e
2 N3ab12002df34403490e5b2397edc8f25
3 N3d009931e4a34d65a43dee334b9754df
4 N41696ef70573416b84898aa8f2bcdd43
5 N48782a7ca0fc4213836a269864e00a3a
6 N5e41562a76b54aa2804dca16d5e0615f
7 N5f00466502ce4294a13bf13e70175a0c
8 N643803948ea84937829836809fd90b07
9 N7f4325cfac3d48f38a3a5e32d1ec3061
10 N97430eedeabe4f25a309bc4dbb18ab92
11 N9cfe2b2acc684164a3a6ee2545b92d35
12 Nb7187425829a47fda6a2107853d74d70
13 Nf5cdcf81a78442f3856bd3701af398aa
14 anzsrc-for:11
15 anzsrc-for:1103
16 schema:author N54353e3ef7424eb6b95abf6044415169
17 schema:citation sg:pub.10.1007/s00421-003-0857-8
18 sg:pub.10.1007/s00421-015-3187-8
19 sg:pub.10.1007/s00726-010-0765-2
20 sg:pub.10.1038/nprot.2008.73
21 sg:pub.10.2165/00007256-200333020-00005
22 schema:datePublished 2017-10-26
23 schema:datePublishedReg 2017-10-26
24 schema:description PurposeTo compare the effects of external pneumatic compression (EPC) and sham when used concurrently with high intensity interval training (HIIT) on performance-related outcomes and recovery-related molecular measures.MethodsEighteen recreationally endurance-trained male participants (age: 21.6 ± 2.4 years, BMI: 25.7 ± 0.5 kg/m2, VO2peak: 51.3 ± 0.9 mL/kg/min) were randomized to balanced sham and EPC treatment groups. Three consecutive days of HIIT followed by EPC/sham treatment (Days 2–4) and 3 consecutive days of recovery (Days 5–7) with EPC/sham only on Days 5–6 were employed. Venipuncture, flexibility and pressure-to-pain threshold (PPT) measurements were made throughout. Vastus lateralis muscle was biopsied at PRE (i.e., Day 1), 1-h post-EPC/sham treatment on Day 2 (POST1), and 24-h post-EPC/sham treatment on Day 7 (POST2). 6-km run time trial performance was tested at PRE and POST2.ResultsNo group × time interaction was observed for flexibility, PPT, or serum measures of creatine kinase (CK), hsCRP, and 8-isoprostane. However, there was a main effect of time for serum CK (p = 0.005). Change from PRE in 6-km run times at POST2 were not significantly different between groups. Significant between-groups differences existed for change from PRE in atrogin-1 mRNA (p = 0.018) at the POST1 time point (EPC: − 19.7 ± 8.1%, sham: + 7.7 ± 5.9%) and atrogin-1 protein concentration (p = 0.013) at the POST2 time point (EPC: − 31.8 ± 7.5%, sham: + 96.0 ± 34.7%). In addition, change from PRE in poly-Ub proteins was significantly different between groups at both the POST1 (EPC: − 26.0 ± 10.3%, sham: + 34.8 ± 28.5%; p = 0.046) and POST2 (EPC: − 33.7 ± 17.2%, sham: + 21.4 ± 14.9%; p = 0.037) time points.ConclusionsEPC when used concurrently with HIIT and in subsequent recovery days reduces skeletal muscle markers of proteolysis.
25 schema:genre article
26 schema:inLanguage en
27 schema:isAccessibleForFree false
28 schema:isPartOf N1edcc0ae963a42eb93c20c5acbdb3e76
29 Ndda7defb27cd4455a198ce3b519a6de9
30 sg:journal.1319730
31 schema:keywords ConclusionsEPC
32 Concomitant external pneumatic compression treatment
33 EPC treatment groups
34 EPC/sham
35 EPC/sham treatment
36 MethodsEighteen
37 POST1
38 POST1 time point
39 POST2
40 POST2 time point
41 PurposeTo
42 addition
43 atrogin-1 mRNA
44 atrogin-1 protein concentration
45 balanced sham
46 changes
47 compression
48 compression treatment
49 concentration
50 consecutive days
51 creatine kinase
52 day 2
53 day 5
54 day 7
55 days
56 differences
57 effect
58 endurance-trained male participants
59 external pneumatic compression
60 external pneumatic compression treatment
61 flexibility
62 group
63 group differences
64 high intensity interval training
65 hsCRP
66 intensity interval training
67 interaction
68 interval training
69 kinase
70 lateralis muscle
71 mRNA
72 main effect
73 male participants
74 markers
75 markers of proteolysis
76 measurements
77 measures
78 molecular measures
79 muscle
80 muscle markers
81 outcomes
82 pain threshold measurements
83 participants
84 performance
85 performance-related outcomes
86 pneumatic compression
87 pneumatic compression treatment
88 point
89 poly-Ub proteins
90 ppt
91 pre
92 pressure
93 protein
94 protein concentration
95 proteolysis
96 recovery
97 recovery days
98 recovery-related molecular measures
99 run time
100 serum creatine kinase
101 serum measures
102 sham
103 sham treatment
104 skeletal muscle markers
105 subsequent recovery days
106 threshold measurements
107 time
108 time interaction
109 time points
110 time trial performance
111 training
112 treatment
113 treatment groups
114 trial performance
115 vastus lateralis muscle
116 venipuncture
117 schema:name Concomitant external pneumatic compression treatment with consecutive days of high intensity interval training reduces markers of proteolysis
118 schema:pagination 2587-2600
119 schema:productId N533039d566de4b5a993c18cb607cd4db
120 Nbadcf271ae48403690443ac775ad0096
121 Nbe00d0c13f3e4bf0aed0d19d7c88c63e
122 schema:sameAs https://app.dimensions.ai/details/publication/pub.1092403878
123 https://doi.org/10.1007/s00421-017-3746-2
124 schema:sdDatePublished 2021-11-01T18:31
125 schema:sdLicense https://scigraph.springernature.com/explorer/license/
126 schema:sdPublisher N4df22ce1936f44ee8d11d968a1995fb9
127 schema:url https://doi.org/10.1007/s00421-017-3746-2
128 sgo:license sg:explorer/license/
129 sgo:sdDataset articles
130 rdf:type schema:ScholarlyArticle
131 N015933377fb940e59f5b3d95933cff9e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
132 schema:name C-Reactive Protein
133 rdf:type schema:DefinedTerm
134 N1edcc0ae963a42eb93c20c5acbdb3e76 schema:volumeNumber 117
135 rdf:type schema:PublicationVolume
136 N3ab12002df34403490e5b2397edc8f25 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
137 schema:name Proteolysis
138 rdf:type schema:DefinedTerm
139 N3d009931e4a34d65a43dee334b9754df schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
140 schema:name Ubiquitination
141 rdf:type schema:DefinedTerm
142 N41696ef70573416b84898aa8f2bcdd43 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
143 schema:name Adult
144 rdf:type schema:DefinedTerm
145 N48782a7ca0fc4213836a269864e00a3a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
146 schema:name Creatine Kinase
147 rdf:type schema:DefinedTerm
148 N4df22ce1936f44ee8d11d968a1995fb9 schema:name Springer Nature - SN SciGraph project
149 rdf:type schema:Organization
150 N533039d566de4b5a993c18cb607cd4db schema:name dimensions_id
151 schema:value pub.1092403878
152 rdf:type schema:PropertyValue
153 N537312bcbc6c43f187941d8a6ac7879d rdf:first sg:person.016357241563.51
154 rdf:rest Nb00a7093fc2f4ea787ea41989f1f1f2a
155 N5388195448b048b5a54553216fd7e2e7 rdf:first sg:person.01270313251.04
156 rdf:rest Nfcefd3e951b6430facf7652eee3f328a
157 N54353e3ef7424eb6b95abf6044415169 rdf:first sg:person.014650750541.38
158 rdf:rest Ne90800b0bab8403e82a5609c69050db1
159 N5d6ddcb7b7ac4766a378aa8ffaa81e5f rdf:first sg:person.0661135551.43
160 rdf:rest N5388195448b048b5a54553216fd7e2e7
161 N5e41562a76b54aa2804dca16d5e0615f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
162 schema:name SKP Cullin F-Box Protein Ligases
163 rdf:type schema:DefinedTerm
164 N5f00466502ce4294a13bf13e70175a0c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
165 schema:name Muscle Proteins
166 rdf:type schema:DefinedTerm
167 N643803948ea84937829836809fd90b07 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
168 schema:name Quadriceps Muscle
169 rdf:type schema:DefinedTerm
170 N691545f8b7df42a3930f10ca173e5419 rdf:first sg:person.013021022047.78
171 rdf:rest N6bc3bdfbc02a41808e77af6423f4c756
172 N6bc3bdfbc02a41808e77af6423f4c756 rdf:first sg:person.01154064651.37
173 rdf:rest N82c9a3c925c645ccb59cb52a0ce6923c
174 N7af98da9d14347ccafcea5b9f6e9ba4a rdf:first sg:person.01105751451.72
175 rdf:rest N947e5083b472468d8fc549d494175fa6
176 N7f4325cfac3d48f38a3a5e32d1ec3061 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
177 schema:name Intermittent Pneumatic Compression Devices
178 rdf:type schema:DefinedTerm
179 N82c9a3c925c645ccb59cb52a0ce6923c rdf:first sg:person.011121607313.63
180 rdf:rest N7af98da9d14347ccafcea5b9f6e9ba4a
181 N947e5083b472468d8fc549d494175fa6 rdf:first sg:person.01062370067.57
182 rdf:rest N5d6ddcb7b7ac4766a378aa8ffaa81e5f
183 N97430eedeabe4f25a309bc4dbb18ab92 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
184 schema:name High-Intensity Interval Training
185 rdf:type schema:DefinedTerm
186 N9cfe2b2acc684164a3a6ee2545b92d35 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
187 schema:name Humans
188 rdf:type schema:DefinedTerm
189 Nb00a7093fc2f4ea787ea41989f1f1f2a rdf:first sg:person.01350325772.02
190 rdf:rest N691545f8b7df42a3930f10ca173e5419
191 Nb7187425829a47fda6a2107853d74d70 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
192 schema:name Dinoprost
193 rdf:type schema:DefinedTerm
194 Nbadcf271ae48403690443ac775ad0096 schema:name doi
195 schema:value 10.1007/s00421-017-3746-2
196 rdf:type schema:PropertyValue
197 Nbe00d0c13f3e4bf0aed0d19d7c88c63e schema:name pubmed_id
198 schema:value 29075862
199 rdf:type schema:PropertyValue
200 Ndda7defb27cd4455a198ce3b519a6de9 schema:issueNumber 12
201 rdf:type schema:PublicationIssue
202 Ne90800b0bab8403e82a5609c69050db1 rdf:first sg:person.01366257433.24
203 rdf:rest Ned86d2b51a0a467fa629d0e629321ea7
204 Ned86d2b51a0a467fa629d0e629321ea7 rdf:first sg:person.015561661163.44
205 rdf:rest N537312bcbc6c43f187941d8a6ac7879d
206 Nf5cdcf81a78442f3856bd3701af398aa schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
207 schema:name Male
208 rdf:type schema:DefinedTerm
209 Nfcefd3e951b6430facf7652eee3f328a rdf:first sg:person.012143622537.90
210 rdf:rest rdf:nil
211 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
212 schema:name Medical and Health Sciences
213 rdf:type schema:DefinedTerm
214 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
215 schema:name Clinical Sciences
216 rdf:type schema:DefinedTerm
217 sg:journal.1319730 schema:issn 1432-1025
218 1439-6319
219 schema:name European Journal of Applied Physiology
220 schema:publisher Springer Nature
221 rdf:type schema:Periodical
222 sg:person.01062370067.57 schema:affiliation grid-institutes:grid.252546.2
223 schema:familyName Mumford
224 schema:givenName Petey W.
225 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01062370067.57
226 rdf:type schema:Person
227 sg:person.01105751451.72 schema:affiliation grid-institutes:grid.252546.2
228 schema:familyName Kephart
229 schema:givenName Wesley C.
230 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01105751451.72
231 rdf:type schema:Person
232 sg:person.011121607313.63 schema:affiliation grid-institutes:grid.252546.2
233 schema:familyName Roberson
234 schema:givenName Paul A.
235 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011121607313.63
236 rdf:type schema:Person
237 sg:person.01154064651.37 schema:affiliation grid-institutes:grid.252546.2
238 schema:familyName Mobley
239 schema:givenName Christopher B.
240 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01154064651.37
241 rdf:type schema:Person
242 sg:person.012143622537.90 schema:affiliation grid-institutes:None
243 schema:familyName Martin
244 schema:givenName Jeffrey S.
245 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012143622537.90
246 rdf:type schema:Person
247 sg:person.01270313251.04 schema:affiliation grid-institutes:grid.252546.2
248 schema:familyName Pascoe
249 schema:givenName David D.
250 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01270313251.04
251 rdf:type schema:Person
252 sg:person.013021022047.78 schema:affiliation grid-institutes:grid.252546.2
253 schema:familyName Moore
254 schema:givenName Angelique N.
255 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013021022047.78
256 rdf:type schema:Person
257 sg:person.01350325772.02 schema:affiliation grid-institutes:None
258 schema:familyName Healy
259 schema:givenName James C.
260 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01350325772.02
261 rdf:type schema:Person
262 sg:person.01366257433.24 schema:affiliation grid-institutes:None
263 schema:familyName Roberts
264 schema:givenName Michael D.
265 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01366257433.24
266 rdf:type schema:Person
267 sg:person.014650750541.38 schema:affiliation grid-institutes:grid.252546.2
268 schema:familyName Haun
269 schema:givenName Cody T.
270 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014650750541.38
271 rdf:type schema:Person
272 sg:person.015561661163.44 schema:affiliation grid-institutes:grid.252546.2
273 schema:familyName Romero
274 schema:givenName Matthew A.
275 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015561661163.44
276 rdf:type schema:Person
277 sg:person.016357241563.51 schema:affiliation grid-institutes:grid.252546.2
278 schema:familyName Osburn
279 schema:givenName Shelby C.
280 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016357241563.51
281 rdf:type schema:Person
282 sg:person.0661135551.43 schema:affiliation grid-institutes:grid.252546.2
283 schema:familyName Goodlett
284 schema:givenName Michael D.
285 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0661135551.43
286 rdf:type schema:Person
287 sg:pub.10.1007/s00421-003-0857-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052682625
288 https://doi.org/10.1007/s00421-003-0857-8
289 rdf:type schema:CreativeWork
290 sg:pub.10.1007/s00421-015-3187-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041197553
291 https://doi.org/10.1007/s00421-015-3187-8
292 rdf:type schema:CreativeWork
293 sg:pub.10.1007/s00726-010-0765-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031819481
294 https://doi.org/10.1007/s00726-010-0765-2
295 rdf:type schema:CreativeWork
296 sg:pub.10.1038/nprot.2008.73 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005355981
297 https://doi.org/10.1038/nprot.2008.73
298 rdf:type schema:CreativeWork
299 sg:pub.10.2165/00007256-200333020-00005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029092051
300 https://doi.org/10.2165/00007256-200333020-00005
301 rdf:type schema:CreativeWork
302 grid-institutes:None schema:alternateName Department of Cell Biology and Physiology, Edward Via College of Osteopathic Medicine, Auburn Campus, 910 S. Donahue Drive, 36832, Auburn, AL, USA
303 schema:name Department of Cell Biology and Physiology, Edward Via College of Osteopathic Medicine, Auburn Campus, 910 S. Donahue Drive, 36832, Auburn, AL, USA
304 School of Kinesiology, Auburn University, Auburn, AL, USA
305 rdf:type schema:Organization
306 grid-institutes:grid.252546.2 schema:alternateName Athletics Department, Auburn University, Auburn, AL, USA
307 College of Human Sciences, Auburn University, 36849, Auburn, AL, USA
308 School of Kinesiology, Auburn University, Auburn, AL, USA
309 schema:name Athletics Department, Auburn University, Auburn, AL, USA
310 College of Human Sciences, Auburn University, 36849, Auburn, AL, USA
311 Department of Cell Biology and Physiology, Edward Via College of Osteopathic Medicine, Auburn Campus, 910 S. Donahue Drive, 36832, Auburn, AL, USA
312 School of Kinesiology, Auburn University, Auburn, AL, USA
313 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...