Ontology type: schema:ScholarlyArticle
2010-10
AUTHORSAmelia Guadalupe-Grau, Ignacio Ara, Cecilia Dorado, German Vicente-Rodríguez, Jorge Perez-Gomez, Javier Chavarren Cabrero, José A. Serrano-Sanchez, Alfredo Santana, Jose A. L. Calbet
ABSTRACTOsteocalcin is a hormone produced by osteoblasts which acts as a negative regulator of fat mass, protecting against diet induced obesity and insulin resistance in rodents. To determine if an acute increase in osteocalcin concentration is associated with opposed changes in circulating leptin levels and insulin resistance we studied 15 middle and long distance male triathletes, (age 32.1 ± 6.9 years), before and 48 h after an Olympic (OT) or an Ironman (IT) triathlon competition. Muscle power, anaerobic capacity, body composition (dual-energy X-ray absorptiometry), and serum concentrations of testosterone, dihydrotestosterone, osteocalcin, leptin, glucose, insulin and insulin resistance (HOMA) were determined pre- and post-race. Pre- and 48 h post-race total and regional lean body mass was not altered, but fat mass was similarly increased (~250 g) 48 h after the competitions. This elicited an increase in plasma leptin of 33% after the IT while it remained unchanged after the OT, likely due to a 25% increase in plasma osteocalcin which occurred only after the OT (all p < 0.05). Post-race HOMA remained unchanged in OT and IT. Performance was normalized 48 h after the competitions, with the exception of a slightly lower jumping capacity after the IT. Serum testosterone concentration tended to decrease by 10% after the IT whilst dihydrotestosterone was reduced by 24% after the IT. In conclusion, an acute increase in serum osteocalcin concentration blunts the expected increase of serum leptin concentration that should occur with fat mass gain. This study provides evidence for osteocalcin as a negative regulator of serum leptin in humans. More... »
PAGES635-643
http://scigraph.springernature.com/pub.10.1007/s00421-010-1550-3
DOIhttp://dx.doi.org/10.1007/s00421-010-1550-3
DIMENSIONShttps://app.dimensions.ai/details/publication/pub.1051446036
PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/20574675
JSON-LD is the canonical representation for SciGraph data.
TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT
[
{
"@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json",
"about": [
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Clinical Sciences",
"type": "DefinedTerm"
},
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Medical and Health Sciences",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Adipose Tissue",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Adult",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Athletes",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Athletic Performance",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Bicycling",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Blood Glucose",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Body Composition",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Dihydrotestosterone",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Humans",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Insulin",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Insulin Resistance",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Leptin",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Male",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Osteocalcin",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Running",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Sports",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Swimming",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Testosterone",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Time Factors",
"type": "DefinedTerm"
}
],
"author": [
{
"affiliation": {
"alternateName": "University of Las Palmas de Gran Canaria",
"id": "https://www.grid.ac/institutes/grid.4521.2",
"name": [
"Department of Physical Education, University of Las Palmas de Gran Canaria, Campus Universitario de Tafira s/n, 35017, Las Palmas de Gran Canaria, Canary Island, Spain"
],
"type": "Organization"
},
"familyName": "Guadalupe-Grau",
"givenName": "Amelia",
"id": "sg:person.01117314417.77",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01117314417.77"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Las Palmas de Gran Canaria",
"id": "https://www.grid.ac/institutes/grid.4521.2",
"name": [
"Department of Physical Education, University of Las Palmas de Gran Canaria, Campus Universitario de Tafira s/n, 35017, Las Palmas de Gran Canaria, Canary Island, Spain"
],
"type": "Organization"
},
"familyName": "Ara",
"givenName": "Ignacio",
"id": "sg:person.01020740137.46",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01020740137.46"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Las Palmas de Gran Canaria",
"id": "https://www.grid.ac/institutes/grid.4521.2",
"name": [
"Department of Physical Education, University of Las Palmas de Gran Canaria, Campus Universitario de Tafira s/n, 35017, Las Palmas de Gran Canaria, Canary Island, Spain"
],
"type": "Organization"
},
"familyName": "Dorado",
"givenName": "Cecilia",
"id": "sg:person.0714055113.48",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0714055113.48"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Las Palmas de Gran Canaria",
"id": "https://www.grid.ac/institutes/grid.4521.2",
"name": [
"Department of Physical Education, University of Las Palmas de Gran Canaria, Campus Universitario de Tafira s/n, 35017, Las Palmas de Gran Canaria, Canary Island, Spain"
],
"type": "Organization"
},
"familyName": "Vicente-Rodr\u00edguez",
"givenName": "German",
"id": "sg:person.01313667237.61",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01313667237.61"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Las Palmas de Gran Canaria",
"id": "https://www.grid.ac/institutes/grid.4521.2",
"name": [
"Department of Physical Education, University of Las Palmas de Gran Canaria, Campus Universitario de Tafira s/n, 35017, Las Palmas de Gran Canaria, Canary Island, Spain"
],
"type": "Organization"
},
"familyName": "Perez-Gomez",
"givenName": "Jorge",
"id": "sg:person.0705467200.06",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0705467200.06"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Las Palmas de Gran Canaria",
"id": "https://www.grid.ac/institutes/grid.4521.2",
"name": [
"Department of Physical Education, University of Las Palmas de Gran Canaria, Campus Universitario de Tafira s/n, 35017, Las Palmas de Gran Canaria, Canary Island, Spain"
],
"type": "Organization"
},
"familyName": "Cabrero",
"givenName": "Javier Chavarren",
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Las Palmas de Gran Canaria",
"id": "https://www.grid.ac/institutes/grid.4521.2",
"name": [
"Department of Physical Education, University of Las Palmas de Gran Canaria, Campus Universitario de Tafira s/n, 35017, Las Palmas de Gran Canaria, Canary Island, Spain"
],
"type": "Organization"
},
"familyName": "Serrano-Sanchez",
"givenName": "Jos\u00e9 A.",
"id": "sg:person.01225672663.50",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01225672663.50"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Las Palmas de Gran Canaria",
"id": "https://www.grid.ac/institutes/grid.4521.2",
"name": [
"Department of Physical Education, University of Las Palmas de Gran Canaria, Campus Universitario de Tafira s/n, 35017, Las Palmas de Gran Canaria, Canary Island, Spain",
"Genetic Unit, Childhood Hospital-Materno Infantil de Las Palmas, Avenida Mar\u00edtima, del Sur s/n, 35016, Las Palmas de Gran Canaria, Spain",
"Research Unit, Hospital de Gran Canaria Doctor Negr\u00edn, Bco Ballena s/n, 35013, Las Palmas de Gran Canaria, Spain"
],
"type": "Organization"
},
"familyName": "Santana",
"givenName": "Alfredo",
"id": "sg:person.01125421727.54",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01125421727.54"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Las Palmas de Gran Canaria",
"id": "https://www.grid.ac/institutes/grid.4521.2",
"name": [
"Department of Physical Education, University of Las Palmas de Gran Canaria, Campus Universitario de Tafira s/n, 35017, Las Palmas de Gran Canaria, Canary Island, Spain"
],
"type": "Organization"
},
"familyName": "Calbet",
"givenName": "Jose A. L.",
"id": "sg:person.013375211604.13",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013375211604.13"
],
"type": "Person"
}
],
"citation": [
{
"id": "https://doi.org/10.1152/japplphysiol.00128.2002",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1002735321"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s004210050492",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1002792347",
"https://doi.org/10.1007/s004210050492"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1080/026404100365009",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1006391231"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.3945/ajcn.2009.28151",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1007989785"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/jcb.10385",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1008134172"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/ijo.2009.282",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1008423326",
"https://doi.org/10.1038/ijo.2009.282"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1515/cclm.2007.282",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1008919060"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1249/mss.0b013e31818313e6",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1010850824"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1249/mss.0b013e31818313e6",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1010850824"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1249/mss.0b013e31818313e6",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1010850824"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s00421-007-0648-8",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1013210791",
"https://doi.org/10.1007/s00421-007-0648-8"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s00421-007-0648-8",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1013210791",
"https://doi.org/10.1007/s00421-007-0648-8"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1373/clinchem.2007.102657",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1013505666"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1249/00005768-198910001-00013",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1016389165"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1080/15438620701878881",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1017120432"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1073/pnas.0711119105",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1017447548"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1515/cclm.2002.023",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1018048068"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.2165/00007256-200131030-00004",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1019016395",
"https://doi.org/10.2165/00007256-200131030-00004"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.2165/00007256-200131030-00004",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1019016395",
"https://doi.org/10.2165/00007256-200131030-00004"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s00421-008-0787-6",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1022059933",
"https://doi.org/10.1007/s00421-008-0787-6"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1080/15438620902900260",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1023222745"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.bone.2009.07.088",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1026479318"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1139/h08-026",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1027761317"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1080/03014460050044865",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1027766520"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/bf00280883",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1027902786",
"https://doi.org/10.1007/bf00280883"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/bf00280883",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1027902786",
"https://doi.org/10.1007/bf00280883"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/bf00280883",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1027902786",
"https://doi.org/10.1007/bf00280883"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s002239900467",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1028753176",
"https://doi.org/10.1007/s002239900467"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1152/japplphysiol.00580.2006",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1029212032"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1210/jc.2004-0386",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1029432893"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1371/journal.pone.0003466",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1032731009"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s00421-002-0731-0",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1033529469",
"https://doi.org/10.1007/s00421-002-0731-0"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/00042752-200211000-00012",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1037759909"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/bf00298720",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1040830349",
"https://doi.org/10.1007/bf00298720"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1152/japplphysiol.91469.2008",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1041144954"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.2165/00007256-200232060-00001",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1041593744",
"https://doi.org/10.2165/00007256-200232060-00001"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.2165/00007256-200232060-00001",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1041593744",
"https://doi.org/10.2165/00007256-200232060-00001"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s00198-010-1184-7",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1041684407",
"https://doi.org/10.1007/s00198-010-1184-7"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s00198-010-1184-7",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1041684407",
"https://doi.org/10.1007/s00198-010-1184-7"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0009-8981(00)00427-7",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1043613521"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s11932-007-0039-2",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1048094852",
"https://doi.org/10.1007/s11932-007-0039-2"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s11932-007-0039-2",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1048094852",
"https://doi.org/10.1007/s11932-007-0039-2"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1136/bjsm.2003.007187",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1049999235"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/bf00428958",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1050121216",
"https://doi.org/10.1007/bf00428958"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1359/jbmr.081234",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1052024262"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1136/bjsm.2007.038034",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1053487544"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1055/s-0030-1248331",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1057214109"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1055/s-2005-837621",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1057441100"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1055/s-2007-964841",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1057498101"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1055/s-2007-972628",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1057504920"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1055/s-2007-972982",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1057505272"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1055/s-2008-1025914",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1057526672"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1123/ijsnem.12.1.47",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1062421343"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1210/jc.2002-020037",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1064286177"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1210/jc.2008-0270",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1064290560"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1210/jc.2008-1422",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1064290852"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1210/jc.2008-1455",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1064290861"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1210/jc.83.9.3243",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1064300406"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1210/jc.85.1.124",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1064301005"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.3748/wjg.v10.i18.2711",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1071362475"
],
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1076848774",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1077442628",
"type": "CreativeWork"
}
],
"datePublished": "2010-10",
"datePublishedReg": "2010-10-01",
"description": "Osteocalcin is a hormone produced by osteoblasts which acts as a negative regulator of fat mass, protecting against diet induced obesity and insulin resistance in rodents. To determine if an acute increase in osteocalcin concentration is associated with opposed changes in circulating leptin levels and insulin resistance we studied 15 middle and long distance male triathletes, (age 32.1 \u00b1 6.9 years), before and 48 h after an Olympic (OT) or an Ironman (IT) triathlon competition. Muscle power, anaerobic capacity, body composition (dual-energy X-ray absorptiometry), and serum concentrations of testosterone, dihydrotestosterone, osteocalcin, leptin, glucose, insulin and insulin resistance (HOMA) were determined pre- and post-race. Pre- and 48 h post-race total and regional lean body mass was not altered, but fat mass was similarly increased (~250 g) 48 h after the competitions. This elicited an increase in plasma leptin of 33% after the IT while it remained unchanged after the OT, likely due to a 25% increase in plasma osteocalcin which occurred only after the OT (all p < 0.05). Post-race HOMA remained unchanged in OT and IT. Performance was normalized 48 h after the competitions, with the exception of a slightly lower jumping capacity after the IT. Serum testosterone concentration tended to decrease by 10% after the IT whilst dihydrotestosterone was reduced by 24% after the IT. In conclusion, an acute increase in serum osteocalcin concentration blunts the expected increase of serum leptin concentration that should occur with fat mass gain. This study provides evidence for osteocalcin as a negative regulator of serum leptin in humans.",
"genre": "research_article",
"id": "sg:pub.10.1007/s00421-010-1550-3",
"inLanguage": [
"en"
],
"isAccessibleForFree": false,
"isPartOf": [
{
"id": "sg:journal.1319730",
"issn": [
"1439-6319",
"1432-1025"
],
"name": "European Journal of Applied Physiology",
"type": "Periodical"
},
{
"issueNumber": "3",
"type": "PublicationIssue"
},
{
"type": "PublicationVolume",
"volumeNumber": "110"
}
],
"name": "Osteocalcin as a negative regulator of serum leptin concentration in humans: insight from triathlon competitions",
"pagination": "635-643",
"productId": [
{
"name": "readcube_id",
"type": "PropertyValue",
"value": [
"f5112f99f819ca9a223b4822420719b07e318fab66f2b75ce2a5eb896acdb143"
]
},
{
"name": "pubmed_id",
"type": "PropertyValue",
"value": [
"20574675"
]
},
{
"name": "nlm_unique_id",
"type": "PropertyValue",
"value": [
"100954790"
]
},
{
"name": "doi",
"type": "PropertyValue",
"value": [
"10.1007/s00421-010-1550-3"
]
},
{
"name": "dimensions_id",
"type": "PropertyValue",
"value": [
"pub.1051446036"
]
}
],
"sameAs": [
"https://doi.org/10.1007/s00421-010-1550-3",
"https://app.dimensions.ai/details/publication/pub.1051446036"
],
"sdDataset": "articles",
"sdDatePublished": "2019-04-11T10:33",
"sdLicense": "https://scigraph.springernature.com/explorer/license/",
"sdPublisher": {
"name": "Springer Nature - SN SciGraph project",
"type": "Organization"
},
"sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000349_0000000349/records_113661_00000002.jsonl",
"type": "ScholarlyArticle",
"url": "http://link.springer.com/10.1007%2Fs00421-010-1550-3"
}
]Download the RDF metadata as: json-ld nt turtle xml License info
JSON-LD is a popular format for linked data which is fully compatible with JSON.
curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00421-010-1550-3'
N-Triples is a line-based linked data format ideal for batch operations.
curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00421-010-1550-3'
Turtle is a human-readable linked data format.
curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00421-010-1550-3'
RDF/XML is a standard XML format for linked data.
curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00421-010-1550-3'
This table displays all metadata directly associated to this object as RDF triples.
372 TRIPLES
21 PREDICATES
101 URIs
40 LITERALS
28 BLANK NODES