Phospholipids and inositol phosphates linked to the epigenome View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2018-09

AUTHORS

Lívia Uličná, Darina Paprčková, Veronika Fáberová, Pavel Hozák

ABSTRACT

Even though the majority of knowledge about phospholipids comes from their cytoplasmic functions, in the last decade, it has been shown that nuclear phospholipids and their building blocks, inositol phosphates, have many important roles in the cell nucleus. There are clear connections of phospholipids with the regulation of gene expression and chromatin biology, however, this review focuses on less known functions of nuclear phospholipids in connection with the epigenome regulation. In particular, we highlight the roles of nuclear phospholipids and inositol phosphates that involve histone modifications, such as acetylation or methylation, tightly connected with the cell physiology. This demonstrates the importance of nuclear phospholipids in the regulation of cellular processes, and should encourage further research of nuclear phospholipids and inositol phosphates. More... »

PAGES

245-253

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00418-018-1690-9

DOI

http://dx.doi.org/10.1007/s00418-018-1690-9

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1105406691

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/29982846


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