Changes in the crystalline lens resulting from insertion of a phakic IOL (ICL) into the porcine eye View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2007-01

AUTHORS

Kunitoshi Fujisawa, Kimiya Shimizu, Shigekazu Uga, Masanobu Suzuki, Koichi Nagano, Yuuki Murakami, Hiroko Goseki

ABSTRACT

BACKGROUND: Insertion of a phakic IOL offers these advantages: the corneal optical zone is not dissected or resected; preservation of the crystalline lens results in preservation of the accommodation force; and since the phakic IOL is removable, any error or change in refraction can be countered by exchanging it. However, the cause of secondary cataracts has never been clarified or discussed to date. METHODS: The following ICL lenses were inserted under general anaesthesia into 20 eyes of ten 3-month-old miniature pigs: a minus lens without holes into five eyes, a plus lens in two eyes, a minus lens with four holes around the lens haptics in three eyes, and a minus lens with a central hole in the optic in three eyes; and seven eyes were used as controls. The anterior segments were then photographed 1 week, 1 month and 3 months after surgery. At 3 months after surgery, Evans blue (EB) was infused into the vitreous under general anaesthesia, and after 30 min, the eyeball was enucleated, fixed and examined. RESULTS: In the case of the ICL without holes, the anterior subcapsular opacities were observed in all the eyes, and the anterior surfaces of the crystalline lenses were not stained with EB. Use of the ICL with four holes around the lens haptics resulted in light staining of the anterior surface of the crystalline lens, but the anterior subcapsular opacities observed were mild. As for the ICL with a hole in the centre of the optic, the anterior surface of the crystalline lens was stained and no anterior subcapsular opacities were observed. CONCLUSION: The results suggested that the insertion of an ICL brings about a change in the dynamics of the intraocular aqueous humour, reducing its circulation to the anterior surface of the crystalline lens. This is considered to cause a metabolic disturbance of the crystalline lens, resulting in anterior subcapsular opacification. More... »

PAGES

114-122

References to SciGraph publications

  • 1994-04. Serum albumin enters the posterior chamber of the eye permeating the blood-aqueous barrier in GRAEFE'S ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s00417-006-0338-y

    DOI

    http://dx.doi.org/10.1007/s00417-006-0338-y

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1006414600

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/16639622


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1113", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Ophthalmology and Optometry", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Medical and Health Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Animals", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Aqueous Humor", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Cataract", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Lens Capsule, Crystalline", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Lens Implantation, Intraocular", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Lens, Crystalline", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Lenses, Intraocular", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Postoperative Complications", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Swine", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Swine, Miniature", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "affiliation": {
              "alternateName": "Kitasato University", 
              "id": "https://www.grid.ac/institutes/grid.410786.c", 
              "name": [
                "Department of Ophthalmology, School of Medicine, Kitasato University, 1-15-1 Kitasato, 228-8555, Sagamihara, Kanagawa, Japan"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Fujisawa", 
            "givenName": "Kunitoshi", 
            "id": "sg:person.0727561715.18", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0727561715.18"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Kitasato University", 
              "id": "https://www.grid.ac/institutes/grid.410786.c", 
              "name": [
                "Department of Ophthalmology, School of Medicine, Kitasato University, 1-15-1 Kitasato, 228-8555, Sagamihara, Kanagawa, Japan"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Shimizu", 
            "givenName": "Kimiya", 
            "id": "sg:person.01173355062.13", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01173355062.13"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "International University of Health and Welfare", 
              "id": "https://www.grid.ac/institutes/grid.411731.1", 
              "name": [
                "Department of Orthoptic & Visual Science, School of Health Sciences, International University of Health and Welfare, Otawara, Tochigi, Japan"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Uga", 
            "givenName": "Shigekazu", 
            "id": "sg:person.0772164322.12", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0772164322.12"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Kitasato University", 
              "id": "https://www.grid.ac/institutes/grid.410786.c", 
              "name": [
                "Department of Ophthalmology, School of Medicine, Kitasato University, 1-15-1 Kitasato, 228-8555, Sagamihara, Kanagawa, Japan"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Suzuki", 
            "givenName": "Masanobu", 
            "id": "sg:person.01152561020.16", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01152561020.16"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Kitasato University", 
              "id": "https://www.grid.ac/institutes/grid.410786.c", 
              "name": [
                "Department of Ophthalmology, School of Medicine, Kitasato University, 1-15-1 Kitasato, 228-8555, Sagamihara, Kanagawa, Japan"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Nagano", 
            "givenName": "Koichi", 
            "id": "sg:person.01044010315.13", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01044010315.13"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Kitasato University", 
              "id": "https://www.grid.ac/institutes/grid.410786.c", 
              "name": [
                "Department of Ophthalmology, School of Medicine, Kitasato University, 1-15-1 Kitasato, 228-8555, Sagamihara, Kanagawa, Japan"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Murakami", 
            "givenName": "Yuuki", 
            "id": "sg:person.01112123515.62", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01112123515.62"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Kitasato University", 
              "id": "https://www.grid.ac/institutes/grid.410786.c", 
              "name": [
                "Department of Ophthalmology, School of Medicine, Kitasato University, 1-15-1 Kitasato, 228-8555, Sagamihara, Kanagawa, Japan"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Goseki", 
            "givenName": "Hiroko", 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "https://doi.org/10.1016/s0886-3350(02)01210-5", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1000809495"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.jcrs.2003.09.047", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003191461"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0002-9394(77)90382-8", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003889314"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0021-5155(03)00075-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006837318"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0021-5155(03)00075-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006837318"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0886-3350(00)00759-8", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1011189678"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0161-6420(02)01771-2", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1020169495"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0886-3350(03)00065-8", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1020338318"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0886-3350(03)00065-8", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1020338318"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0161-6420(02)01973-5", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1023142436"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0161-6420(02)01973-5", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1023142436"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf00184013", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1028233729", 
              "https://doi.org/10.1007/bf00184013"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0014-4835(03)00110-6", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1029831732"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0014-4835(03)00110-6", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1029831732"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1159/000063654", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031623803"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0014-4835(78)90113-6", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1032060386"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0886-3350(01)01218-4", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035874283"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0014-4835(81)90006-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039591313"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0886-3350(99)00417-4", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1042124103"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0161-6420(03)00830-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1042124281"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0161-6420(03)00830-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1042124281"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0886-3350(96)80007-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1044764561"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0886-3350(99)80139-4", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1045978434"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.jcrs.2003.06.004", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048173529"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0014-4835(90)90107-6", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048524469"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0886-3350(01)01229-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1051239283"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1074517140", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1076995288", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1081336395", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1083282433", 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "2007-01", 
        "datePublishedReg": "2007-01-01", 
        "description": "BACKGROUND: Insertion of a phakic IOL offers these advantages: the corneal optical zone is not dissected or resected; preservation of the crystalline lens results in preservation of the accommodation force; and since the phakic IOL is removable, any error or change in refraction can be countered by exchanging it. However, the cause of secondary cataracts has never been clarified or discussed to date.\nMETHODS: The following ICL lenses were inserted under general anaesthesia into 20 eyes of ten 3-month-old miniature pigs: a minus lens without holes into five eyes, a plus lens in two eyes, a minus lens with four holes around the lens haptics in three eyes, and a minus lens with a central hole in the optic in three eyes; and seven eyes were used as controls. The anterior segments were then photographed 1 week, 1 month and 3 months after surgery. At 3 months after surgery, Evans blue (EB) was infused into the vitreous under general anaesthesia, and after 30 min, the eyeball was enucleated, fixed and examined.\nRESULTS: In the case of the ICL without holes, the anterior subcapsular opacities were observed in all the eyes, and the anterior surfaces of the crystalline lenses were not stained with EB. Use of the ICL with four holes around the lens haptics resulted in light staining of the anterior surface of the crystalline lens, but the anterior subcapsular opacities observed were mild. As for the ICL with a hole in the centre of the optic, the anterior surface of the crystalline lens was stained and no anterior subcapsular opacities were observed.\nCONCLUSION: The results suggested that the insertion of an ICL brings about a change in the dynamics of the intraocular aqueous humour, reducing its circulation to the anterior surface of the crystalline lens. This is considered to cause a metabolic disturbance of the crystalline lens, resulting in anterior subcapsular opacification.", 
        "genre": "research_article", 
        "id": "sg:pub.10.1007/s00417-006-0338-y", 
        "inLanguage": [
          "en"
        ], 
        "isAccessibleForFree": false, 
        "isPartOf": [
          {
            "id": "sg:journal.1005670", 
            "issn": [
              "0941-2921", 
              "1435-702X"
            ], 
            "name": "Graefe's Archive for Clinical and Experimental Ophthalmology", 
            "type": "Periodical"
          }, 
          {
            "issueNumber": "1", 
            "type": "PublicationIssue"
          }, 
          {
            "type": "PublicationVolume", 
            "volumeNumber": "245"
          }
        ], 
        "name": "Changes in the crystalline lens resulting from insertion of a phakic IOL (ICL) into the porcine eye", 
        "pagination": "114-122", 
        "productId": [
          {
            "name": "readcube_id", 
            "type": "PropertyValue", 
            "value": [
              "1e8e2aa281d9148c91184038194299c35f1d8e8d47352263ed0aa3f947a41dc2"
            ]
          }, 
          {
            "name": "pubmed_id", 
            "type": "PropertyValue", 
            "value": [
              "16639622"
            ]
          }, 
          {
            "name": "nlm_unique_id", 
            "type": "PropertyValue", 
            "value": [
              "8205248"
            ]
          }, 
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1007/s00417-006-0338-y"
            ]
          }, 
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1006414600"
            ]
          }
        ], 
        "sameAs": [
          "https://doi.org/10.1007/s00417-006-0338-y", 
          "https://app.dimensions.ai/details/publication/pub.1006414600"
        ], 
        "sdDataset": "articles", 
        "sdDatePublished": "2019-04-11T14:32", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000373_0000000373/records_13102_00000000.jsonl", 
        "type": "ScholarlyArticle", 
        "url": "http://link.springer.com/10.1007%2Fs00417-006-0338-y"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00417-006-0338-y'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00417-006-0338-y'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00417-006-0338-y'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00417-006-0338-y'


     

    This table displays all metadata directly associated to this object as RDF triples.

    225 TRIPLES      21 PREDICATES      64 URIs      31 LITERALS      19 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1007/s00417-006-0338-y schema:about N08d9351d78d94e38a149916772c62421
    2 N292c6aaa57c8486eadd23fac7fa451e1
    3 N49e72a8041e94745aed46f237170b817
    4 N8a9bde5407bd4bbfaf32f84f9ba02662
    5 Nbc8e3bde8ad348ea8f1ba500e603d9e2
    6 Nc386203d24904720ad6ad5a0372f1306
    7 Ncb96b8eed67f4093b8434b0b1a77bedb
    8 Ne6ec52acd2954f32ac49f84934985f42
    9 Nf8d660fcb51d465586aa40df34475cd8
    10 Nfa8051b580214e0eb85df82872344123
    11 anzsrc-for:11
    12 anzsrc-for:1113
    13 schema:author N17eca9811bb04ad693a05ba18c2ad599
    14 schema:citation sg:pub.10.1007/bf00184013
    15 https://app.dimensions.ai/details/publication/pub.1074517140
    16 https://app.dimensions.ai/details/publication/pub.1076995288
    17 https://app.dimensions.ai/details/publication/pub.1081336395
    18 https://app.dimensions.ai/details/publication/pub.1083282433
    19 https://doi.org/10.1016/0002-9394(77)90382-8
    20 https://doi.org/10.1016/0014-4835(78)90113-6
    21 https://doi.org/10.1016/0014-4835(81)90006-3
    22 https://doi.org/10.1016/0014-4835(90)90107-6
    23 https://doi.org/10.1016/j.jcrs.2003.06.004
    24 https://doi.org/10.1016/j.jcrs.2003.09.047
    25 https://doi.org/10.1016/s0014-4835(03)00110-6
    26 https://doi.org/10.1016/s0021-5155(03)00075-3
    27 https://doi.org/10.1016/s0161-6420(02)01771-2
    28 https://doi.org/10.1016/s0161-6420(02)01973-5
    29 https://doi.org/10.1016/s0161-6420(03)00830-3
    30 https://doi.org/10.1016/s0886-3350(00)00759-8
    31 https://doi.org/10.1016/s0886-3350(01)01218-4
    32 https://doi.org/10.1016/s0886-3350(01)01229-9
    33 https://doi.org/10.1016/s0886-3350(02)01210-5
    34 https://doi.org/10.1016/s0886-3350(03)00065-8
    35 https://doi.org/10.1016/s0886-3350(96)80007-1
    36 https://doi.org/10.1016/s0886-3350(99)00417-4
    37 https://doi.org/10.1016/s0886-3350(99)80139-4
    38 https://doi.org/10.1159/000063654
    39 schema:datePublished 2007-01
    40 schema:datePublishedReg 2007-01-01
    41 schema:description BACKGROUND: Insertion of a phakic IOL offers these advantages: the corneal optical zone is not dissected or resected; preservation of the crystalline lens results in preservation of the accommodation force; and since the phakic IOL is removable, any error or change in refraction can be countered by exchanging it. However, the cause of secondary cataracts has never been clarified or discussed to date. METHODS: The following ICL lenses were inserted under general anaesthesia into 20 eyes of ten 3-month-old miniature pigs: a minus lens without holes into five eyes, a plus lens in two eyes, a minus lens with four holes around the lens haptics in three eyes, and a minus lens with a central hole in the optic in three eyes; and seven eyes were used as controls. The anterior segments were then photographed 1 week, 1 month and 3 months after surgery. At 3 months after surgery, Evans blue (EB) was infused into the vitreous under general anaesthesia, and after 30 min, the eyeball was enucleated, fixed and examined. RESULTS: In the case of the ICL without holes, the anterior subcapsular opacities were observed in all the eyes, and the anterior surfaces of the crystalline lenses were not stained with EB. Use of the ICL with four holes around the lens haptics resulted in light staining of the anterior surface of the crystalline lens, but the anterior subcapsular opacities observed were mild. As for the ICL with a hole in the centre of the optic, the anterior surface of the crystalline lens was stained and no anterior subcapsular opacities were observed. CONCLUSION: The results suggested that the insertion of an ICL brings about a change in the dynamics of the intraocular aqueous humour, reducing its circulation to the anterior surface of the crystalline lens. This is considered to cause a metabolic disturbance of the crystalline lens, resulting in anterior subcapsular opacification.
    42 schema:genre research_article
    43 schema:inLanguage en
    44 schema:isAccessibleForFree false
    45 schema:isPartOf N167e0621019644bf9bb4743727b99ddb
    46 N50f3defb7b9545d49b860b2f2f52db41
    47 sg:journal.1005670
    48 schema:name Changes in the crystalline lens resulting from insertion of a phakic IOL (ICL) into the porcine eye
    49 schema:pagination 114-122
    50 schema:productId N3535c0fea07a4353ab5e5fce5e3cc3f1
    51 N4d9b8fee3fd1488eadb0ea4ca52762d3
    52 Nd0d94b7add034e81924375f4153cd7c2
    53 Ne430e35c3ac041e4b644194495823b70
    54 Nfcc5e8313a3e4a17adf72d1f4db1108a
    55 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006414600
    56 https://doi.org/10.1007/s00417-006-0338-y
    57 schema:sdDatePublished 2019-04-11T14:32
    58 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    59 schema:sdPublisher N3b5cbc11faa149a7916aab5ec93f15ac
    60 schema:url http://link.springer.com/10.1007%2Fs00417-006-0338-y
    61 sgo:license sg:explorer/license/
    62 sgo:sdDataset articles
    63 rdf:type schema:ScholarlyArticle
    64 N08d9351d78d94e38a149916772c62421 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    65 schema:name Lens, Crystalline
    66 rdf:type schema:DefinedTerm
    67 N167e0621019644bf9bb4743727b99ddb schema:issueNumber 1
    68 rdf:type schema:PublicationIssue
    69 N17eca9811bb04ad693a05ba18c2ad599 rdf:first sg:person.0727561715.18
    70 rdf:rest Nbb3aa300e78044f38fc99e6bc9aa7494
    71 N292c6aaa57c8486eadd23fac7fa451e1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    72 schema:name Swine, Miniature
    73 rdf:type schema:DefinedTerm
    74 N31c751d9c3dc407f8b44a7ab90d16798 rdf:first sg:person.0772164322.12
    75 rdf:rest Nc83b2678dab247e0bebb75e5b12e8973
    76 N3535c0fea07a4353ab5e5fce5e3cc3f1 schema:name readcube_id
    77 schema:value 1e8e2aa281d9148c91184038194299c35f1d8e8d47352263ed0aa3f947a41dc2
    78 rdf:type schema:PropertyValue
    79 N3b5cbc11faa149a7916aab5ec93f15ac schema:name Springer Nature - SN SciGraph project
    80 rdf:type schema:Organization
    81 N49e72a8041e94745aed46f237170b817 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    82 schema:name Animals
    83 rdf:type schema:DefinedTerm
    84 N4d9b8fee3fd1488eadb0ea4ca52762d3 schema:name dimensions_id
    85 schema:value pub.1006414600
    86 rdf:type schema:PropertyValue
    87 N50f3defb7b9545d49b860b2f2f52db41 schema:volumeNumber 245
    88 rdf:type schema:PublicationVolume
    89 N8a9bde5407bd4bbfaf32f84f9ba02662 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    90 schema:name Postoperative Complications
    91 rdf:type schema:DefinedTerm
    92 Nb9b8d2497f384eb4be5cb1463589676f rdf:first sg:person.01112123515.62
    93 rdf:rest Ned0d79165cd447c5a9fa18981d6c1703
    94 Nbb3aa300e78044f38fc99e6bc9aa7494 rdf:first sg:person.01173355062.13
    95 rdf:rest N31c751d9c3dc407f8b44a7ab90d16798
    96 Nbc8e3bde8ad348ea8f1ba500e603d9e2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    97 schema:name Swine
    98 rdf:type schema:DefinedTerm
    99 Nc386203d24904720ad6ad5a0372f1306 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    100 schema:name Aqueous Humor
    101 rdf:type schema:DefinedTerm
    102 Nc83b2678dab247e0bebb75e5b12e8973 rdf:first sg:person.01152561020.16
    103 rdf:rest Nd376a77e50b546bfbda8ce114bc21c45
    104 Nc89bc88e480d4776b9c458eb993e449f schema:affiliation https://www.grid.ac/institutes/grid.410786.c
    105 schema:familyName Goseki
    106 schema:givenName Hiroko
    107 rdf:type schema:Person
    108 Ncb96b8eed67f4093b8434b0b1a77bedb schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    109 schema:name Cataract
    110 rdf:type schema:DefinedTerm
    111 Nd0d94b7add034e81924375f4153cd7c2 schema:name doi
    112 schema:value 10.1007/s00417-006-0338-y
    113 rdf:type schema:PropertyValue
    114 Nd376a77e50b546bfbda8ce114bc21c45 rdf:first sg:person.01044010315.13
    115 rdf:rest Nb9b8d2497f384eb4be5cb1463589676f
    116 Ne430e35c3ac041e4b644194495823b70 schema:name nlm_unique_id
    117 schema:value 8205248
    118 rdf:type schema:PropertyValue
    119 Ne6ec52acd2954f32ac49f84934985f42 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    120 schema:name Lenses, Intraocular
    121 rdf:type schema:DefinedTerm
    122 Ned0d79165cd447c5a9fa18981d6c1703 rdf:first Nc89bc88e480d4776b9c458eb993e449f
    123 rdf:rest rdf:nil
    124 Nf8d660fcb51d465586aa40df34475cd8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    125 schema:name Lens Implantation, Intraocular
    126 rdf:type schema:DefinedTerm
    127 Nfa8051b580214e0eb85df82872344123 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    128 schema:name Lens Capsule, Crystalline
    129 rdf:type schema:DefinedTerm
    130 Nfcc5e8313a3e4a17adf72d1f4db1108a schema:name pubmed_id
    131 schema:value 16639622
    132 rdf:type schema:PropertyValue
    133 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
    134 schema:name Medical and Health Sciences
    135 rdf:type schema:DefinedTerm
    136 anzsrc-for:1113 schema:inDefinedTermSet anzsrc-for:
    137 schema:name Ophthalmology and Optometry
    138 rdf:type schema:DefinedTerm
    139 sg:journal.1005670 schema:issn 0941-2921
    140 1435-702X
    141 schema:name Graefe's Archive for Clinical and Experimental Ophthalmology
    142 rdf:type schema:Periodical
    143 sg:person.01044010315.13 schema:affiliation https://www.grid.ac/institutes/grid.410786.c
    144 schema:familyName Nagano
    145 schema:givenName Koichi
    146 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01044010315.13
    147 rdf:type schema:Person
    148 sg:person.01112123515.62 schema:affiliation https://www.grid.ac/institutes/grid.410786.c
    149 schema:familyName Murakami
    150 schema:givenName Yuuki
    151 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01112123515.62
    152 rdf:type schema:Person
    153 sg:person.01152561020.16 schema:affiliation https://www.grid.ac/institutes/grid.410786.c
    154 schema:familyName Suzuki
    155 schema:givenName Masanobu
    156 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01152561020.16
    157 rdf:type schema:Person
    158 sg:person.01173355062.13 schema:affiliation https://www.grid.ac/institutes/grid.410786.c
    159 schema:familyName Shimizu
    160 schema:givenName Kimiya
    161 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01173355062.13
    162 rdf:type schema:Person
    163 sg:person.0727561715.18 schema:affiliation https://www.grid.ac/institutes/grid.410786.c
    164 schema:familyName Fujisawa
    165 schema:givenName Kunitoshi
    166 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0727561715.18
    167 rdf:type schema:Person
    168 sg:person.0772164322.12 schema:affiliation https://www.grid.ac/institutes/grid.411731.1
    169 schema:familyName Uga
    170 schema:givenName Shigekazu
    171 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0772164322.12
    172 rdf:type schema:Person
    173 sg:pub.10.1007/bf00184013 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028233729
    174 https://doi.org/10.1007/bf00184013
    175 rdf:type schema:CreativeWork
    176 https://app.dimensions.ai/details/publication/pub.1074517140 schema:CreativeWork
    177 https://app.dimensions.ai/details/publication/pub.1076995288 schema:CreativeWork
    178 https://app.dimensions.ai/details/publication/pub.1081336395 schema:CreativeWork
    179 https://app.dimensions.ai/details/publication/pub.1083282433 schema:CreativeWork
    180 https://doi.org/10.1016/0002-9394(77)90382-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003889314
    181 rdf:type schema:CreativeWork
    182 https://doi.org/10.1016/0014-4835(78)90113-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032060386
    183 rdf:type schema:CreativeWork
    184 https://doi.org/10.1016/0014-4835(81)90006-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039591313
    185 rdf:type schema:CreativeWork
    186 https://doi.org/10.1016/0014-4835(90)90107-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048524469
    187 rdf:type schema:CreativeWork
    188 https://doi.org/10.1016/j.jcrs.2003.06.004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048173529
    189 rdf:type schema:CreativeWork
    190 https://doi.org/10.1016/j.jcrs.2003.09.047 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003191461
    191 rdf:type schema:CreativeWork
    192 https://doi.org/10.1016/s0014-4835(03)00110-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029831732
    193 rdf:type schema:CreativeWork
    194 https://doi.org/10.1016/s0021-5155(03)00075-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006837318
    195 rdf:type schema:CreativeWork
    196 https://doi.org/10.1016/s0161-6420(02)01771-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020169495
    197 rdf:type schema:CreativeWork
    198 https://doi.org/10.1016/s0161-6420(02)01973-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023142436
    199 rdf:type schema:CreativeWork
    200 https://doi.org/10.1016/s0161-6420(03)00830-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042124281
    201 rdf:type schema:CreativeWork
    202 https://doi.org/10.1016/s0886-3350(00)00759-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011189678
    203 rdf:type schema:CreativeWork
    204 https://doi.org/10.1016/s0886-3350(01)01218-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035874283
    205 rdf:type schema:CreativeWork
    206 https://doi.org/10.1016/s0886-3350(01)01229-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051239283
    207 rdf:type schema:CreativeWork
    208 https://doi.org/10.1016/s0886-3350(02)01210-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000809495
    209 rdf:type schema:CreativeWork
    210 https://doi.org/10.1016/s0886-3350(03)00065-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020338318
    211 rdf:type schema:CreativeWork
    212 https://doi.org/10.1016/s0886-3350(96)80007-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044764561
    213 rdf:type schema:CreativeWork
    214 https://doi.org/10.1016/s0886-3350(99)00417-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042124103
    215 rdf:type schema:CreativeWork
    216 https://doi.org/10.1016/s0886-3350(99)80139-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045978434
    217 rdf:type schema:CreativeWork
    218 https://doi.org/10.1159/000063654 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031623803
    219 rdf:type schema:CreativeWork
    220 https://www.grid.ac/institutes/grid.410786.c schema:alternateName Kitasato University
    221 schema:name Department of Ophthalmology, School of Medicine, Kitasato University, 1-15-1 Kitasato, 228-8555, Sagamihara, Kanagawa, Japan
    222 rdf:type schema:Organization
    223 https://www.grid.ac/institutes/grid.411731.1 schema:alternateName International University of Health and Welfare
    224 schema:name Department of Orthoptic & Visual Science, School of Health Sciences, International University of Health and Welfare, Otawara, Tochigi, Japan
    225 rdf:type schema:Organization
     




    Preview window. Press ESC to close (or click here)


    ...