Genetic abnormalities in oligodendroglial and ependymal tumours View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2001-12

AUTHORS

Ann C. Goussia, Athanassios P. Kyritsis, Paraskevi Mitlianga, Janet M. Bruner

ABSTRACT

Oligodendroglial and ependymal tumours are not the most common glial neoplasms; however, they are important subtypes of gliomas with different tumour biologies. Cytogenetic information has suggested that losses of chromosomes 1 p and 19 q are the most frequent genetic alterations in oligodendroglial tumours. Combined loss of these chromosomes has been associated with better chemotherapeutic response and prolonged overall survival. Loss of chromosome 22 is a well defined abnormality in ependymomas. In addition, deletion of chromosome 6 q may be another frequent chromosomic aberration in paediatric ependymomas. More... »

PAGES

1030-1035

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s004150170021

DOI

http://dx.doi.org/10.1007/s004150170021

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1031329089

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/12013578


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