Autosomal dominant cerebellar ataxia type I: oculomotor abnormalities in families with SCA1, SCA2, and SCA3 View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1999-09

AUTHORS

K. Bürk, M. Fetter, M. Abele, F. Laccone, A. Brice, J. Dichgans, T. Klockgether

ABSTRACT

Forty-six patients suffering from autosomal dominant cerebellar ataxia type I (ADCA I) underwent to a genotype-phenotype correlation analysis by molecular genetic assignment to the spinocerebellar ataxia type 1, 2, or 3 (SCA1, SCA2, SCA3) genetic locus and electro-oculography. Oculomotor deficits that are attributed to dysfunction of cerebellar structures occurred in all three mutations without major differences between the groups. Gaze-evoked nystagmus, however, was not found to be associated with SCA2. Square wave jerks were exclusively observed in SCA3. The gain in vestibulo-ocular reflex was significantly impaired in SCA3 and SCA1. In SCA3 the severity of vestibular impairment increased with CAG repeat length. Severe saccade slowing was a highly characteristic feature of SCA2. In SCA3 saccade velocity was normal to mildly reduced while SCA1 fell into an intermediate range. The present data show that each mutation is associated with a distinct syndrome of oculomotor deficits. Reduced saccade velocity and the absence of both square-wave jerks and gaze-evoked nystagmus allow one SCA2 to be distinguished from SCA3 patients in almost all cases. The eye movement disorder of SCA1 patients, however, overlaps with both SCA2 and SCA3. More... »

PAGES

789-797

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s004150050456

DOI

http://dx.doi.org/10.1007/s004150050456

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1034905313

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/10525976


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1109", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Neurosciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adult", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cerebellar Ataxia", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Electrooculography", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Eye Movements", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Middle Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mutation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Nystagmus, Optokinetic", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Oculomotor Muscles", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Pursuit, Smooth", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Reflex, Vestibulo-Ocular", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Saccades", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Vestibule, Labyrinth", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Department of Neurology,  University of T\u00fcbingen,  Hoppe-Seyler-Strasse 3,  D-72076 T\u00fcbingen, Germany e-mail: buerk@uni-tuebingen.de,  Tel.: +49-7071-2982141,  Fax: +49-7071-295260, DE", 
          "id": "http://www.grid.ac/institutes/grid.10392.39", 
          "name": [
            "Department of Neurology,  University of T\u00fcbingen,  Hoppe-Seyler-Strasse 3,  D-72076 T\u00fcbingen, Germany e-mail: buerk@uni-tuebingen.de,  Tel.: +49-7071-2982141,  Fax: +49-7071-295260, DE"
          ], 
          "type": "Organization"
        }, 
        "familyName": "B\u00fcrk", 
        "givenName": "K.", 
        "id": "sg:person.0771470427.54", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0771470427.54"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Neurology,  University of T\u00fcbingen,  Hoppe-Seyler-Strasse 3,  D-72076 T\u00fcbingen, Germany e-mail: buerk@uni-tuebingen.de,  Tel.: +49-7071-2982141,  Fax: +49-7071-295260, DE", 
          "id": "http://www.grid.ac/institutes/grid.10392.39", 
          "name": [
            "Department of Neurology,  University of T\u00fcbingen,  Hoppe-Seyler-Strasse 3,  D-72076 T\u00fcbingen, Germany e-mail: buerk@uni-tuebingen.de,  Tel.: +49-7071-2982141,  Fax: +49-7071-295260, DE"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Fetter", 
        "givenName": "M.", 
        "id": "sg:person.01356335430.25", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01356335430.25"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Neurology,  University of T\u00fcbingen,  Hoppe-Seyler-Strasse 3,  D-72076 T\u00fcbingen, Germany e-mail: buerk@uni-tuebingen.de,  Tel.: +49-7071-2982141,  Fax: +49-7071-295260, DE", 
          "id": "http://www.grid.ac/institutes/grid.10392.39", 
          "name": [
            "Department of Neurology,  University of T\u00fcbingen,  Hoppe-Seyler-Strasse 3,  D-72076 T\u00fcbingen, Germany e-mail: buerk@uni-tuebingen.de,  Tel.: +49-7071-2982141,  Fax: +49-7071-295260, DE"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Abele", 
        "givenName": "M.", 
        "id": "sg:person.01011105161.29", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01011105161.29"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Human Genetics,  University of G\u00f6ttingen,  D-35651 G\u00f6ttingen, Germany, DE", 
          "id": "http://www.grid.ac/institutes/grid.7450.6", 
          "name": [
            "Department of Human Genetics,  University of G\u00f6ttingen,  D-35651 G\u00f6ttingen, Germany, DE"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Laccone", 
        "givenName": "F.", 
        "id": "sg:person.01210641702.78", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01210641702.78"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "INSERM U 289, H\u00f4pital de la Salp\u00eatri\u00e8re, F-75651 Paris Cedex 13, France, FR", 
          "id": "http://www.grid.ac/institutes/grid.411439.a", 
          "name": [
            "INSERM U 289, H\u00f4pital de la Salp\u00eatri\u00e8re, F-75651 Paris Cedex 13, France, FR"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Brice", 
        "givenName": "A.", 
        "id": "sg:person.01022777420.63", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01022777420.63"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Neurology,  University of T\u00fcbingen,  Hoppe-Seyler-Strasse 3,  D-72076 T\u00fcbingen, Germany e-mail: buerk@uni-tuebingen.de,  Tel.: +49-7071-2982141,  Fax: +49-7071-295260, DE", 
          "id": "http://www.grid.ac/institutes/grid.10392.39", 
          "name": [
            "Department of Neurology,  University of T\u00fcbingen,  Hoppe-Seyler-Strasse 3,  D-72076 T\u00fcbingen, Germany e-mail: buerk@uni-tuebingen.de,  Tel.: +49-7071-2982141,  Fax: +49-7071-295260, DE"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Dichgans", 
        "givenName": "J.", 
        "id": "sg:person.01162526546.32", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01162526546.32"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Neurology,  University of T\u00fcbingen,  Hoppe-Seyler-Strasse 3,  D-72076 T\u00fcbingen, Germany e-mail: buerk@uni-tuebingen.de,  Tel.: +49-7071-2982141,  Fax: +49-7071-295260, DE", 
          "id": "http://www.grid.ac/institutes/grid.10392.39", 
          "name": [
            "Department of Neurology,  University of T\u00fcbingen,  Hoppe-Seyler-Strasse 3,  D-72076 T\u00fcbingen, Germany e-mail: buerk@uni-tuebingen.de,  Tel.: +49-7071-2982141,  Fax: +49-7071-295260, DE"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Klockgether", 
        "givenName": "T.", 
        "id": "sg:person.01327524222.39", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01327524222.39"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1038/ng1194-221", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036365552", 
          "https://doi.org/10.1038/ng1194-221"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ng0793-295", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013454954", 
          "https://doi.org/10.1038/ng0793-295"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00341710", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033757011", 
          "https://doi.org/10.1007/bf00341710"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s004150050081", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025045611", 
          "https://doi.org/10.1007/s004150050081"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ng0793-221", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024789892", 
          "https://doi.org/10.1038/ng0793-221"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ng1196-285", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019198906", 
          "https://doi.org/10.1038/ng1196-285"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "1999-09", 
    "datePublishedReg": "1999-09-01", 
    "description": "Abstract Forty-six patients suffering from autosomal dominant cerebellar ataxia type I (ADCA I) underwent to a genotype-phenotype correlation analysis by molecular genetic assignment to the spinocerebellar ataxia type 1, 2, or 3 (SCA1, SCA2, SCA3) genetic locus and electro-oculography. Oculomotor deficits that are attributed to dysfunction of cerebellar structures occurred in all three mutations without major differences between the groups. Gaze-evoked nystagmus, however, was not found to be associated with SCA2. Square wave jerks were exclusively observed in SCA3. The gain in vestibulo-ocular reflex was significantly impaired in SCA3 and SCA1. In SCA3 the severity of vestibular impairment increased with CAG repeat length. Severe saccade slowing was a highly characteristic feature of SCA2. In SCA3 saccade velocity was normal to mildly reduced while SCA1 fell into an intermediate range. The present data show that each mutation is associated with a distinct syndrome of oculomotor deficits. Reduced saccade velocity and the absence of both square-wave jerks and gaze-evoked nystagmus allow one SCA2 to be distinguished from SCA3 patients in almost all cases. The eye movement disorder of SCA1 patients, however, overlaps with both SCA2 and SCA3.", 
    "genre": "article", 
    "id": "sg:pub.10.1007/s004150050456", 
    "inLanguage": "en", 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1014525", 
        "issn": [
          "0340-5354", 
          "1432-1459"
        ], 
        "name": "Journal of Neurology", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "9", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "246"
      }
    ], 
    "keywords": [
      "oculomotor deficits", 
      "saccade velocity", 
      "gaze-evoked nystagmus", 
      "square-wave jerks", 
      "vestibulo-ocular reflex", 
      "eye movement disorders", 
      "square wave jerks", 
      "CAG repeat length", 
      "genotype-phenotype correlation analysis", 
      "molecular genetic assignment", 
      "vestibular impairment", 
      "oculomotor abnormalities", 
      "saccade slowing", 
      "movement disorders", 
      "spinocerebellar ataxia type 1", 
      "SCA3 patients", 
      "distinct syndrome", 
      "type 1", 
      "ataxia type 1", 
      "SCA1 patients", 
      "patients", 
      "cerebellar structures", 
      "autosomal dominant cerebellar ataxia type I", 
      "SCA3", 
      "Abstract Forty", 
      "nystagmus", 
      "SCA2", 
      "type I", 
      "present data", 
      "SCA1", 
      "deficits", 
      "repeat length", 
      "jerks", 
      "dysfunction", 
      "reflex", 
      "syndrome", 
      "abnormalities", 
      "severity", 
      "impairment", 
      "genetic loci", 
      "mutations", 
      "disorders", 
      "major differences", 
      "characteristic features", 
      "correlation analysis", 
      "forties", 
      "group", 
      "slowing", 
      "absence", 
      "differences", 
      "cases", 
      "gaze", 
      "family", 
      "data", 
      "gain", 
      "length", 
      "features", 
      "analysis", 
      "loci", 
      "intermediate range", 
      "velocity", 
      "range", 
      "assignment", 
      "structure", 
      "electro", 
      "genetic assignment", 
      "dominant cerebellar ataxia type I", 
      "cerebellar ataxia type I", 
      "ataxia type I", 
      "wave jerks", 
      "Severe saccade slowing", 
      "SCA3 saccade velocity"
    ], 
    "name": "Autosomal dominant cerebellar ataxia type I: oculomotor abnormalities in families with SCA1, SCA2, and SCA3", 
    "pagination": "789-797", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1034905313"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s004150050456"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "10525976"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s004150050456", 
      "https://app.dimensions.ai/details/publication/pub.1034905313"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-01-01T18:09", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20220101/entities/gbq_results/article/article_312.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1007/s004150050456"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s004150050456'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s004150050456'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s004150050456'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s004150050456'


 

This table displays all metadata directly associated to this object as RDF triples.

274 TRIPLES      22 PREDICATES      122 URIs      107 LITERALS      23 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s004150050456 schema:about N1480047f578b466a90b75c545207f6a7
2 N1ad7f471fa50405dad569a73edbdc7e8
3 N40d32175b03243e58b2f9cd510cf98eb
4 N4b9ebbc0650640b896222b552d57408d
5 N56dcba1a5d1b4585b1fa6c6c26ad7df6
6 N609fe0241ef3420babba8af3e127b049
7 N68a9aa2da3614304bfe908549cd3c08f
8 N6a9408f5cf0241ea8450535df7f4fc4a
9 N6aec8163fc094ee98c26088eaf3da702
10 N86afcba75bce4f52bb7b0fcc56ccf03c
11 Na2a394cb85e94371ba850847ff8240af
12 Na4bc429722d848cab42037047bd66658
13 Nb1aac18193b94758a71393c42692657a
14 Nbd441a41985b498098bd1557ba0bc6c3
15 Ne37fe4b3d0874764a5524e842ee7e76f
16 Nf60a35b8568b4f53a250a70ec005d112
17 anzsrc-for:11
18 anzsrc-for:1103
19 anzsrc-for:1109
20 schema:author Neb305d9feb654492b519a2c41decd457
21 schema:citation sg:pub.10.1007/bf00341710
22 sg:pub.10.1007/s004150050081
23 sg:pub.10.1038/ng0793-221
24 sg:pub.10.1038/ng0793-295
25 sg:pub.10.1038/ng1194-221
26 sg:pub.10.1038/ng1196-285
27 schema:datePublished 1999-09
28 schema:datePublishedReg 1999-09-01
29 schema:description Abstract Forty-six patients suffering from autosomal dominant cerebellar ataxia type I (ADCA I) underwent to a genotype-phenotype correlation analysis by molecular genetic assignment to the spinocerebellar ataxia type 1, 2, or 3 (SCA1, SCA2, SCA3) genetic locus and electro-oculography. Oculomotor deficits that are attributed to dysfunction of cerebellar structures occurred in all three mutations without major differences between the groups. Gaze-evoked nystagmus, however, was not found to be associated with SCA2. Square wave jerks were exclusively observed in SCA3. The gain in vestibulo-ocular reflex was significantly impaired in SCA3 and SCA1. In SCA3 the severity of vestibular impairment increased with CAG repeat length. Severe saccade slowing was a highly characteristic feature of SCA2. In SCA3 saccade velocity was normal to mildly reduced while SCA1 fell into an intermediate range. The present data show that each mutation is associated with a distinct syndrome of oculomotor deficits. Reduced saccade velocity and the absence of both square-wave jerks and gaze-evoked nystagmus allow one SCA2 to be distinguished from SCA3 patients in almost all cases. The eye movement disorder of SCA1 patients, however, overlaps with both SCA2 and SCA3.
30 schema:genre article
31 schema:inLanguage en
32 schema:isAccessibleForFree false
33 schema:isPartOf N9b8d9bb3c5a04f8abcf1c02538490dcc
34 Nec17071c7866435bb278afedca550d2a
35 sg:journal.1014525
36 schema:keywords Abstract Forty
37 CAG repeat length
38 SCA1
39 SCA1 patients
40 SCA2
41 SCA3
42 SCA3 patients
43 SCA3 saccade velocity
44 Severe saccade slowing
45 abnormalities
46 absence
47 analysis
48 assignment
49 ataxia type 1
50 ataxia type I
51 autosomal dominant cerebellar ataxia type I
52 cases
53 cerebellar ataxia type I
54 cerebellar structures
55 characteristic features
56 correlation analysis
57 data
58 deficits
59 differences
60 disorders
61 distinct syndrome
62 dominant cerebellar ataxia type I
63 dysfunction
64 electro
65 eye movement disorders
66 family
67 features
68 forties
69 gain
70 gaze
71 gaze-evoked nystagmus
72 genetic assignment
73 genetic loci
74 genotype-phenotype correlation analysis
75 group
76 impairment
77 intermediate range
78 jerks
79 length
80 loci
81 major differences
82 molecular genetic assignment
83 movement disorders
84 mutations
85 nystagmus
86 oculomotor abnormalities
87 oculomotor deficits
88 patients
89 present data
90 range
91 reflex
92 repeat length
93 saccade slowing
94 saccade velocity
95 severity
96 slowing
97 spinocerebellar ataxia type 1
98 square wave jerks
99 square-wave jerks
100 structure
101 syndrome
102 type 1
103 type I
104 velocity
105 vestibular impairment
106 vestibulo-ocular reflex
107 wave jerks
108 schema:name Autosomal dominant cerebellar ataxia type I: oculomotor abnormalities in families with SCA1, SCA2, and SCA3
109 schema:pagination 789-797
110 schema:productId N795639ef1f63480d8ba527d63a650ec1
111 Ncdaf12e8d7bb4dc7a3160c6a3b2dbf33
112 Nf8c4a6298fee4801a499b1dbca623c6d
113 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034905313
114 https://doi.org/10.1007/s004150050456
115 schema:sdDatePublished 2022-01-01T18:09
116 schema:sdLicense https://scigraph.springernature.com/explorer/license/
117 schema:sdPublisher Nea54e6c189014c66b391c72845fa9d7a
118 schema:url https://doi.org/10.1007/s004150050456
119 sgo:license sg:explorer/license/
120 sgo:sdDataset articles
121 rdf:type schema:ScholarlyArticle
122 N1480047f578b466a90b75c545207f6a7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
123 schema:name Middle Aged
124 rdf:type schema:DefinedTerm
125 N1ad7f471fa50405dad569a73edbdc7e8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
126 schema:name Nystagmus, Optokinetic
127 rdf:type schema:DefinedTerm
128 N39189743c8fe43638a2eca317514d195 rdf:first sg:person.01327524222.39
129 rdf:rest rdf:nil
130 N40d32175b03243e58b2f9cd510cf98eb schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
131 schema:name Female
132 rdf:type schema:DefinedTerm
133 N44b49238040648b48dfa7ec3814b1626 rdf:first sg:person.01210641702.78
134 rdf:rest N8f628e3331d14d74aa3db9b6e3de3e6f
135 N4b9ebbc0650640b896222b552d57408d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
136 schema:name Eye Movements
137 rdf:type schema:DefinedTerm
138 N56dcba1a5d1b4585b1fa6c6c26ad7df6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
139 schema:name Reflex, Vestibulo-Ocular
140 rdf:type schema:DefinedTerm
141 N609fe0241ef3420babba8af3e127b049 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
142 schema:name Aged
143 rdf:type schema:DefinedTerm
144 N68a9aa2da3614304bfe908549cd3c08f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
145 schema:name Cerebellar Ataxia
146 rdf:type schema:DefinedTerm
147 N6a9408f5cf0241ea8450535df7f4fc4a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
148 schema:name Oculomotor Muscles
149 rdf:type schema:DefinedTerm
150 N6aec8163fc094ee98c26088eaf3da702 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
151 schema:name Mutation
152 rdf:type schema:DefinedTerm
153 N795639ef1f63480d8ba527d63a650ec1 schema:name dimensions_id
154 schema:value pub.1034905313
155 rdf:type schema:PropertyValue
156 N86afcba75bce4f52bb7b0fcc56ccf03c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
157 schema:name Saccades
158 rdf:type schema:DefinedTerm
159 N878e58b516844ce39165bafdd639e3a7 rdf:first sg:person.01356335430.25
160 rdf:rest Na842ef6f6dd2487f82d784ca1cca4f78
161 N8f628e3331d14d74aa3db9b6e3de3e6f rdf:first sg:person.01022777420.63
162 rdf:rest Nc40ca9d4edd14829a6cf72c483ea66dc
163 N9b8d9bb3c5a04f8abcf1c02538490dcc schema:issueNumber 9
164 rdf:type schema:PublicationIssue
165 Na2a394cb85e94371ba850847ff8240af schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
166 schema:name Electrooculography
167 rdf:type schema:DefinedTerm
168 Na4bc429722d848cab42037047bd66658 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
169 schema:name Adult
170 rdf:type schema:DefinedTerm
171 Na842ef6f6dd2487f82d784ca1cca4f78 rdf:first sg:person.01011105161.29
172 rdf:rest N44b49238040648b48dfa7ec3814b1626
173 Nb1aac18193b94758a71393c42692657a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
174 schema:name Male
175 rdf:type schema:DefinedTerm
176 Nbd441a41985b498098bd1557ba0bc6c3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
177 schema:name Pursuit, Smooth
178 rdf:type schema:DefinedTerm
179 Nc40ca9d4edd14829a6cf72c483ea66dc rdf:first sg:person.01162526546.32
180 rdf:rest N39189743c8fe43638a2eca317514d195
181 Ncdaf12e8d7bb4dc7a3160c6a3b2dbf33 schema:name pubmed_id
182 schema:value 10525976
183 rdf:type schema:PropertyValue
184 Ne37fe4b3d0874764a5524e842ee7e76f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
185 schema:name Humans
186 rdf:type schema:DefinedTerm
187 Nea54e6c189014c66b391c72845fa9d7a schema:name Springer Nature - SN SciGraph project
188 rdf:type schema:Organization
189 Neb305d9feb654492b519a2c41decd457 rdf:first sg:person.0771470427.54
190 rdf:rest N878e58b516844ce39165bafdd639e3a7
191 Nec17071c7866435bb278afedca550d2a schema:volumeNumber 246
192 rdf:type schema:PublicationVolume
193 Nf60a35b8568b4f53a250a70ec005d112 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
194 schema:name Vestibule, Labyrinth
195 rdf:type schema:DefinedTerm
196 Nf8c4a6298fee4801a499b1dbca623c6d schema:name doi
197 schema:value 10.1007/s004150050456
198 rdf:type schema:PropertyValue
199 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
200 schema:name Medical and Health Sciences
201 rdf:type schema:DefinedTerm
202 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
203 schema:name Clinical Sciences
204 rdf:type schema:DefinedTerm
205 anzsrc-for:1109 schema:inDefinedTermSet anzsrc-for:
206 schema:name Neurosciences
207 rdf:type schema:DefinedTerm
208 sg:journal.1014525 schema:issn 0340-5354
209 1432-1459
210 schema:name Journal of Neurology
211 schema:publisher Springer Nature
212 rdf:type schema:Periodical
213 sg:person.01011105161.29 schema:affiliation grid-institutes:grid.10392.39
214 schema:familyName Abele
215 schema:givenName M.
216 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01011105161.29
217 rdf:type schema:Person
218 sg:person.01022777420.63 schema:affiliation grid-institutes:grid.411439.a
219 schema:familyName Brice
220 schema:givenName A.
221 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01022777420.63
222 rdf:type schema:Person
223 sg:person.01162526546.32 schema:affiliation grid-institutes:grid.10392.39
224 schema:familyName Dichgans
225 schema:givenName J.
226 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01162526546.32
227 rdf:type schema:Person
228 sg:person.01210641702.78 schema:affiliation grid-institutes:grid.7450.6
229 schema:familyName Laccone
230 schema:givenName F.
231 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01210641702.78
232 rdf:type schema:Person
233 sg:person.01327524222.39 schema:affiliation grid-institutes:grid.10392.39
234 schema:familyName Klockgether
235 schema:givenName T.
236 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01327524222.39
237 rdf:type schema:Person
238 sg:person.01356335430.25 schema:affiliation grid-institutes:grid.10392.39
239 schema:familyName Fetter
240 schema:givenName M.
241 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01356335430.25
242 rdf:type schema:Person
243 sg:person.0771470427.54 schema:affiliation grid-institutes:grid.10392.39
244 schema:familyName Bürk
245 schema:givenName K.
246 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0771470427.54
247 rdf:type schema:Person
248 sg:pub.10.1007/bf00341710 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033757011
249 https://doi.org/10.1007/bf00341710
250 rdf:type schema:CreativeWork
251 sg:pub.10.1007/s004150050081 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025045611
252 https://doi.org/10.1007/s004150050081
253 rdf:type schema:CreativeWork
254 sg:pub.10.1038/ng0793-221 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024789892
255 https://doi.org/10.1038/ng0793-221
256 rdf:type schema:CreativeWork
257 sg:pub.10.1038/ng0793-295 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013454954
258 https://doi.org/10.1038/ng0793-295
259 rdf:type schema:CreativeWork
260 sg:pub.10.1038/ng1194-221 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036365552
261 https://doi.org/10.1038/ng1194-221
262 rdf:type schema:CreativeWork
263 sg:pub.10.1038/ng1196-285 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019198906
264 https://doi.org/10.1038/ng1196-285
265 rdf:type schema:CreativeWork
266 grid-institutes:grid.10392.39 schema:alternateName Department of Neurology, University of Tübingen, Hoppe-Seyler-Strasse 3, D-72076 Tübingen, Germany e-mail: buerk@uni-tuebingen.de, Tel.: +49-7071-2982141, Fax: +49-7071-295260, DE
267 schema:name Department of Neurology, University of Tübingen, Hoppe-Seyler-Strasse 3, D-72076 Tübingen, Germany e-mail: buerk@uni-tuebingen.de, Tel.: +49-7071-2982141, Fax: +49-7071-295260, DE
268 rdf:type schema:Organization
269 grid-institutes:grid.411439.a schema:alternateName INSERM U 289, Hôpital de la Salpêtrière, F-75651 Paris Cedex 13, France, FR
270 schema:name INSERM U 289, Hôpital de la Salpêtrière, F-75651 Paris Cedex 13, France, FR
271 rdf:type schema:Organization
272 grid-institutes:grid.7450.6 schema:alternateName Department of Human Genetics, University of Göttingen, D-35651 Göttingen, Germany, DE
273 schema:name Department of Human Genetics, University of Göttingen, D-35651 Göttingen, Germany, DE
274 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...