Clinical features and outcome of patients with primary central nervous system lymphoma admitted to the intensive care unit: a French ... View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2021-01-16

AUTHORS

Maxens Decavèle, Aliénor Dreyfus, Nicolas Gatulle, Nicolas Weiss, Caroline Houillier, Sophie Demeret, Julien Mayaux, Isabelle Rivals, Martin Dres, Julie Delemazure, Elise Morawiec, Charles-Edouard Luyt, Khe Hoang-Xuan, Sylvain Choquet, Thomas Similowski, Alexandre Demoule

ABSTRACT

IntroductionTo describe the reasons for intensive care unit (ICU) admission and to evaluate the outcomes and prognostic factors of patients with primary central nervous system lymphoma (PCNSL) admitted to the ICU.Patients and methodsRetrospective observational cohort study of 101 PCNSL patients admitted to 3 ICUs over a two-decade period.ResultsAcute respiratory failure, mainly secondary to aspiration pneumonia and Pneumocystis jirovecii pneumonia, was the leading reason for ICU admission (33%). Aspiration pneumonia was more common in patients with brainstem tumor (67% vs. 0%, p < 0.001), whereas patients with intracranial hypertension were more frequently admitted for coma without seizures (61% vs. 9%, p = 0.004). Hospital and 6-month mortality were 47% and 53%, respectively. In multivariate analysis, admission for coma without seizures (OR 7.28), cancer progression (OR 3.47), mechanical ventilation (OR 6.58) and vasopressors (OR 4.07) were associated with higher 6-month mortality. Karnofsky performance status prior to ICU admission was independently associated with lower 6-month mortality (OR 0.96).DiscussionSix-month survival of PCNSL patients admitted to the ICU appears to be relatively favorable (around 50%) and the presence of PCNSL alone is not a relevant criterion for ICU refusal. Predictive factors of mortality may help clinicians to make optimal triage decisions. More... »

PAGES

2141-2150

References to SciGraph publications

  • 2014-06-06. Evaluation of hydrocephalus and other cerebrospinal fluid disorders with MRI: An update in INSIGHTS INTO IMAGING
  • 2010-06-06. Primary CNS lymphoma in HIV positive and negative patients: comparison of clinical characteristics, outcome and prognostic factors in JOURNAL OF NEURO-ONCOLOGY
  • 2003. Pneumocystis carinii pneumonia in HIV negative patients with primary brain tumors in JOURNAL OF NEURO-ONCOLOGY
  • 2017-10-09. Prognosis of patients with primary malignant brain tumors admitted to the intensive care unit: a two-decade experience in JOURNAL OF NEUROLOGY
  • 2009-09-19. Six-month prognosis of patients with lung cancer admitted to the intensive care unit in INTENSIVE CARE MEDICINE
  • 2018-12-07. Etiology and prognosis of acute respiratory failure in patients with primary malignant brain tumors admitted to the intensive care unit in JOURNAL OF NEURO-ONCOLOGY
  • 2015-11-25. Neuro-oncological patients admitted in intensive-care unit: predictive factors and functional outcome in JOURNAL OF NEURO-ONCOLOGY
  • 1996-07. The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure in INTENSIVE CARE MEDICINE
  • 2017-04-21. Rituximab, methotrexate, procarbazine, vincristine and intensified cytarabine consolidation for primary central nervous system lymphoma (PCNSL) in the elderly: a LOC network study in JOURNAL OF NEURO-ONCOLOGY
  • 2017-04-28. Improved survival in primary central nervous system lymphoma up to age 70 only: a population-based study on incidence, primary treatment and survival in the Netherlands, 1989–2015 in LEUKEMIA
  • 2016-05-09. The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary in ACTA NEUROPATHOLOGICA
  • 2009-12-18. Monotherapy with methotrexate for primary central nervous lymphoma has single agent activity in the absence of radiotherapy: a single institution cohort in JOURNAL OF NEURO-ONCOLOGY
  • 2002-10-25. Impact of neutropenia duration on short-term mortality in neutropenic critically ill cancer patients in INTENSIVE CARE MEDICINE
  • 2020-06-13. High-dose methotrexate in ICU patients: a retrospective study in ANNALS OF INTENSIVE CARE
  • 2019-05-29. Changes in critically ill cancer patients’ short-term outcome over the last decades: results of systematic review with meta-analysis on individual data in INTENSIVE CARE MEDICINE
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s00415-021-10396-x

    DOI

    http://dx.doi.org/10.1007/s00415-021-10396-x

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1134631915

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/33452932


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