Symptomatic paroxysmal dysarthria-ataxia in demyelinating diseases View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2010-03-30

AUTHORS

Christophe Marcel, Mathieu Anheim, Constance Flamand-Rouvière, Françoise Heran, Pascal Masnou, Clotilde Boulay, Ivan Mari, Christine Tranchant, Emmanuel Roze

ABSTRACT

Paroxysmal dysarthria-ataxia syndrome (PDA) is a rare neurological disorder that can be either primary or symptomatic of acute neurological dysfunction. Episodes of symptomatic PDA are poorly documented and there are no video reports. We describe the cases of two patients with symptomatic PDA related to demyelinating diseases. Detailed studies of the patients’ speech disorders showed that the dysarthria and gait disorders were of the ataxic type in both cases. Both patients had midbrain lesions at or below the level of the red nucleus, confirming that this area is critically involved in PDA. The best clinical signs for distinguishing between symptomatic and primary PDA are adult onset and short (<1 min) episodes in the former. If these signs are present, brain MRI should be used to identify a cause of symptomatic PDA. More... »

PAGES

1369-1372

References to SciGraph publications

  • 1974-03. Paroxysmale Dysarthrie und Ataxie in JOURNAL OF NEUROLOGY
  • 1995-05. Paroxysmal dysarthria and ataxia in a patient with Behçet's disease in JOURNAL OF NEUROLOGY
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s00415-010-5534-3

    DOI

    http://dx.doi.org/10.1007/s00415-010-5534-3

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1027344539

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/20352251


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