Y chromosome STR haplotypes in four populations from northwest Africa View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2000-12

AUTHORS

E. Bosch, F. Calafell, A. Pérez-Lezaun, D. Comas, H. Izaabel, O. Akhayat, A. Sefiani, G. Hariti, J. M. Dugoujon, J. Bertranpetit

ABSTRACT

The eight short tandem repeat (STR) polymorphic systems mapping on the male-specific region of the human Y chromosome, DYS19, DYS388, DYS389I, DYS389II, DYS390, DYS391, DYS392 and DYS393, were typed in four populations from northwest (NW) Africa (Moroccan Arabs, southern Moroccan Berbers, Saharawis and Mozabites). Allele frequency distributions showed statistically significant differences for all loci among all the populations except for DYS19. Complete typing was obtained for 185 chromosomes, which showed 74 different haplotypes. The two most frequent haplotypes were found in 16.2% and 15.1% of the individuals, although the latter was almost exclusively found in the Mozabites. Locus and haplotype informativeness were measured by means of the gene diversity (D). The haplotype diversity ranged from 0.856 (Mozabites) to 0.967 (southern Moroccan Berbers). For some loci, allele frequencies in NW Africans were clearly different from those in Europeans. The most common NW African haplotype was found only in one individual out of a total of 494 Europeans typed for the whole STR set. Thus, NW African and European Y chromosomes are clearly differentiated. More... »

PAGES

36-40

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s004140000136

DOI

http://dx.doi.org/10.1007/s004140000136

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1034732026

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/11197625


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